Moderna

First dose given inadvertently on 4/7/2021. Error noted during second appt. 2nd dose administered per MD & CDC guidelines. Next day phone encounter with urgent care re: facial swelling, fatigue, nausea, poor PO, Temp 100. MD recommended supportive care, Tylenol, Ibuprofen, Benadryl prn and gave ER precautions.

Within 30 minutes of receiving the vaccine her face swollen up. She was transported to ER. Her sister took her. They treated with an allergic reaction with steroids and Benadryl. She came home after being treated. Today - she starting having body aches and a fever.

Received the Moderna Vaccine at 1549. Presented to the ED at 1635 with c/o localized swelling, lip swelling with right facial swelling.

Swelling, pain and redness for the first few days. Then led to an anaphylactic reaction and had to get IM steroids and Benadryl.

2/9 1pm swelling of rt lymph nodes in neck 8pm 100.4 temp - tylenol & difficulty breathing when laying down - albuterol inhaler, humidifier 02 at 97-99

Patient received vaccine around 430pm. As she was sitting for post-vaccine observation she told an associate to call over Rph due to side effects. After speaking with patient she stated that her arm was numb (vaccinated arm) and that it hurt more than when she got her flu shot. I assessed both arms an her vaccinated arm was slightly swollen. I described the signs of anaphylaxis to her and told her that i would like for her to stay longer for extra monitoring and to alarm me or one of my associates if any anaphylaxis symptoms occur. Patients blood pressure was taken reading - 132/96. Patient was unsure of her baseline so i explained i will check again shortly. Patient was given water and one dose of Benadryl (25mg) at 5:25pm as well as an ice pack to place on her arm. At 6:00pm patients blood pressure was retaken (124/82) and patient stated she was well enough to go home. Her grandma was with her and stated she didn't have Benadryl at home, I recommend her to get some and gave the patient another dose (25mg) before her grandma took her home. Patient has no primary care physician.

Enlarged lymph node under right arm pit. Currently on antibiotics and steroids for it. Not sure outcome quite yet.

Approximately 7-8 minutes after receiving the vaccine, started to feel light-headed, thought she was going to pass out, and her heart was racing extremely high. The health care team at the site took her blood pressure, measured heart rate, gave her water, juice and chocolate and tried to get her heart rate to drop. It was fluctuating up and down and she couldn't stand up without dizziness; we waited 45 minutes and then drove her home as she was unable to drive her own car. She was experiencing significant lightheadedness, and consistent heart racing even while lying down on the sofa/bed. This continued for several days and she stayed home from school and sports. We called her primary care doctor on the 10th and they suggested she wait another day to see how she was feeling. She started to feel a bit better by Friday, was still experiencing a bit of the tiredness, nauseous, light-headed and heart spikes, but was able to drive, move around. On Sunday evening, she started to experience increased heart rate again, lymph nodes were very painful and started experiencing the light headedness all evening. On Monday we took her to her primary care provider and they then referred her to ER for the heart racing and a EKG. The increased light headedness, feeling like she will pass out even while laying in bed, dizziness has all increased and her lymph nodes continue to be swollen and painful. It has been over a week since the vaccine and there is no clear sign of her reaction getting any better, if not worse. The EKG results indicated a new abnormality and we are trying to get her to a cardiologist. She is and had been a very healthy, varsity athlete that runs over 30 hours a week with track, and since receiving the first dose of the Moderna vaccine is unable to move very far within the house without feeling that she is going to pass out or that her heart rate is shooting up uncontrollably.

Low grade fever, shivers, feeling crappy on day one and two. Day 3, 4, and 5 feeling better, but swollen lymph nodes. Today, day 6, low grade fever is back, and lymph nodes are really swollen and painful

About 72 hours after her 2nd Moderna vaccine, patient developed an uncommon condition known as Lipschutz ulcers. It is a non sexually transmitted condition characterized by the rapid onset of painful, necrotic ulcerations of the vulva or lower vagina. Pt presented with moderate unilateral labial swelling, several vulvar ulcers noted to inner labia minora with yellow/bloody discharge. Some ulcers with necrotic appearing tissue. Extremely tender to touch. Pt without hx of EBV infection.

Severe full body ache and fatigue starting around 11pm, fever of 102°, and migraine continuing for about 36 hours. Full body fatigue for about 12 hours following resolution of body aches. Minor and herpetiform vulvar aphthous sores beginning ~60 hours post injection and resolving 7 days after first appearance.

Pt developed fevers > 103F, severe headache, transaminitis, hypoxia (ultimately requiring 7L/min O2 via nasal cannula), and severe pancytopenia resulting in hospitalization and a bone marrow biopsy w/ flow cytometry (ultimately negative for leukemia/lymphoma). Her symptoms improved with IV decadron> oral prednisone, though cytopenias are now recurring 4/14/21. Pt had a positive ANA to 2.72 (but was taking doxycycline for anaplasmosis- now PCR and AB titers are negative for Anaplasma) and a positive ENA AB, Anti-Ro is high at 8.0. She has no family hx of autoimmune disease. Her infectious work-up for HIV, EBV, CMV, Blastomycosis, Histoplasmosis, Coccidioides, tickborne pathogens, & ricketsial disease is negative.

I started feeling feverish around 2:00 am the day after I received the second dose, and I also had a swollen lymph node in the left side of my neck which caused a lot of throat pain and difficulty swallowing. The fever symptoms went away around 24 hours after I received the shot, but my throat continued to hurt until about 72 hours after.

Cannot even walk around normally; swollen lymph nodes; patient cannot walk with out dizziness; Dizziness with room spinning; Unstable blood pressure; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of DIZZINESS POSTURAL (patient cannot walk with out dizziness) in an 18-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 036A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. The patient's past medical history included No adverse event (No medical history reported.). On 09-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 09-Feb-2021, the patient experienced DIZZINESS POSTURAL (patient cannot walk with out dizziness) (seriousness criterion disability), DIZZINESS (Dizziness with room spinning) and BLOOD PRESSURE FLUCTUATION (Unstable blood pressure). On 13-Feb-2021, the patient experienced LYMPHADENOPATHY (swollen lymph nodes). On an unknown date, the patient experienced GAIT INABILITY (Cannot even walk around normally). At the time of the report, DIZZINESS POSTURAL (patient cannot walk with out dizziness), DIZZINESS (Dizziness with room spinning), BLOOD PRESSURE FLUCTUATION (Unstable blood pressure), GAIT INABILITY (Cannot even walk around normally) and LYMPHADENOPATHY (swollen lymph nodes) had not resolved. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 09-Feb-2021, Heart rate: increased (High) increased. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown. Relevant Text: The Patient's mother reported that the patient received their first dose on 9 Feb 2021 and approximately 10 minutes post receiving the vaccine the patient developed severe dizziness and had an increase in their heart rate. The patient also had an unstable blood pressure. Few days later, the patient developed swelling in their lymph nodes. The reporter reported that the symptoms were still ongoing and now the patient cannot even walk without dizziness. It was also reported that the patient cannot even get back to the competitive sports and was not able to walk around anymore normally. The patient had multiple visits to the cardiologist, ENT, and pediatrician with no clear explanation of what happened to the patient. No Concomitant product use was reported. No treatment information was provided. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Looking at the clinical scenario, the event postural dizziness is persisting 6wks from onset with no clear explanation, it is assessed as a SAE (disability). However, medical history and concomitant medications, reports of tests/diagnostics are needed for further assessment. Additional information is requested.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Looking at the clinical scenario, the event postural dizziness is persisting 6wks from onset with no clear explanation, it is assessed as a SAE (disability). However, medical history and concomitant medications, reports of tests/diagnostics are needed for further assessment. Additional information is requested.

Symptoms began with a tingling sensation in the back corner of the mouth, which spread to the rest of the cheek. Pain similar to the tension of muscles was felt upon touching the left jaw and neck area. Soon it was noticed that left cheek/jaw area was swollen.

approximately 3 weeks after the covid vaccination was received, my daughter began not feeling well. She was experiencing extreme fatigue, substantially enlarged lymph nodes, a slight sore throat and mild sinus stuffiness. Depending on the thermometer used, she either had no fever or a very low grade fever (less than 100).

My arm because sore under my armpit on April 27, 2021 and by April 30,2021 my arm became very red and swollen in the arm that was injected. By May 7, 2021 the swelling and pain were gone.

received her 2nd dose and within 3 minutes she complained of Left Arm pain.....by 5 minutes it was moderate pain and her left antecubital area was reddened, swollen with a hard area the size of a quarter. Within 10 minutes, her arm was in severe pain and her left hand was cool and mottled. She was transported to the ER and was diagnosed with "lymphadenopathy reaction" and was sent home. About 12 hours later, she woke up at 3am with shallow breathing and facial swelling, she was transported to Emergency Room and was treated for an "allergic reaction to vaccine" and released.

swelling of throat, difficulty swallowing. patient went to emergency room after leaving and reported diagnosis of anaphylaxis

The first day, I had slight arm soreness with nothing more. When I woke up on day two, I noticed my arm had swelled more than usual (basing off my previous dose in my right arm) and was extremely hot, tender, and had two circular red patches. That night, the redness and swelling had spread into a medium sized circle, and began to itch and still be very hot upon touch. Upon looking later that night, at approximately 11pm EST, the swelling and redness had gotten larger. On day three, the redness only got worse, and is slowly spread more over the area, with intense itching, but no longer is as sore as it was the day prior. I have iced the area, moved my arm around more to help the swelling go down, taken a hot shower, and about 600mg of Ibuprofen each day since the second dose. The only outcome to those treatments has been a significant decrease in pain level, but the swelling and redness still continues. This has all been over about a 48-72 hour time period

Febrile beginning at 1600, 100.5 degrees, peaking at 2100, 104degrees, accompanied with tightness in chest with mild difficulty breathing and extreme muscle weakness most notably in extremities, bilaterally. Needed assistance to stand and could not hold a pencil to write. Also numbness and tingling in hands and fingers. Face slightly swollen and red. 400 mg Ibuprofen was administered at 1530. Pushed fluids as soon as fever began. Cooling measures provided, cool shower, cold compress, change of clothes to light pajamas. We contacted our Insurance 24 hour Nurse line at approximately 2100 when symptoms peaked. The RN on staff instructed us to seek immediate medical care. We attempted to find an open Urgent Care unsuccessfully and tried to go to an ER but they were full. Fever began to come down around 2230, so we returned home. Continued with ibuprofen every six hours and cooling measures.

After the second shot, she has had ongoing headaches and painful swelling in her extremities that comes and goes. For instance, one day her entire palm of her hand, the next day her fingers, the next day the sole of her foot, a few days later it will be just one finger. It is very odd, but she has never had this issue. Also, she has never suffered from headaches until after this second shot. This has been going on for almost a month. We don't know what to do about it.

Continuous headaches and swelling in extremities. Has been ongoing for the past month. Has not received treatment. Have been taking over the counter medication

Site: Pain at Injection Site-Mild, Site: Swelling at Injection Site-Mild, Systemic: Allergic: Swelling of Face / Eyes / Mouth / Tongue-Medium, Additional Details: Patient stated her eyes were extremely swollen post vaccine and she is currently still recovering (Day 3). She has been taking benadryl and the swelling around both eyes has slowly gone down. Her eye sight is not effected, but she was very concerned.

The patient developed progressively worsening dyspnea, GI symptoms and fevers starting 5/16/2021, 3.5 weeks after receiving second Moderna vaccine. She was admitted 5/22/2021 with ARDS requiring intubation, found to have severe systemic inflammation with acute DVT of right right subclavian, axillary, brachial, and upper arm radial veins, chronic DVT of left subclavian, and possible thrombus tricuspid valve. Remains intubated with ongoing evidence of systemic inflammation. Working diagnosis EVALI.

Shaking and being severely cold - June 15,2021 around 10 pm (took 2 Advil to try and relieve symptoms) Feeling very lightheaded and feeling close to passing out - June 16,2021 (took 2 Advil to help with symptoms) Left underarm lymph node beginning to swell up - June 17,2021

On June 7th, I took the Second Dose Moderna, after that I have fever on the next two day, which is the 8 and the 9. Nothing happens on the 10, however after my mom came home from work she recognized a strange circle on my neck, it seems like an Adam?s apple. But it is really big. And I visited my doctor at the 14th the same month at 3:45, at first he suspect that I have a Thyromegaly. And I took the Blood Test. However after a several day, the test came out and it says I have a Hyperthyroidism. He advice me to report to VAERS and give me an orders to take the Thyroid Ultrasound, and the Thyroid Uptake Scan. I already made appointments, and I will do it the next 2 weeks.

The very next morning after the vaccination around 7:00 AM , my right arm was hurting, it was not red, or there wasn't any bruising. I had tightness in my throat, it was pretty much like an anaphylactic shock is how the doctors described it. I had white bumps, like welts, on the back of my throat and tongue. And the roof of my mouth and my tongue, my lips everything in my mouth was swollen. My eyes were almost swollen shut. On 12/27/2021, I had a doctor video visit. He advised me to take Benadryl, and Tylenol, I used my albuterol inhaler several times because I couldn't breath. So around 3:00 pm I went to the Emergency Room because I was still having a hard time breathing and the swelling wasn't going down. The doctor immediately gave me an Epi pen. and told me i had an allergic reaction to the vaccination. The doctor advised me that it was up to me to take the 2nd vaccination . He said it was up to me.

My arm became incredibly sore within an hour. I woke up in the middle of the night aching like I had the flu. The body aches were so intense I couldn?t dress myself in the morning. All of my lymph nodes in my neck, ribs, and collar bones were incredibly swollen and hurt when touched. I rotated Tylenol and Advil with no relief. My fatigue was like no other. My headache wouldn?t go away either. 48 hours after the vaccine, I still had body aches and swollen lymph nodes in my neck to the point of pain when turning my neck.

Begin with abdominal pain on December 30 when she woke up, continued with nausea, then headaches, loss of appetite and by Sunday January 3, 2021 swollen lymph node in left arm pit. Was seen on January 4, 2021, told to call or return if it gets worse. As of today she still has a swollen lymph node and swelling and redness around her injection site.

injection site has been itchy since i got the shot. i noticed about four days ago that my lymph nodes in my left armpit were super tender. about six days after injection left neck lymph nodes became extremely swollen and tender. on day seven i noticed a rash all over my upper left arm from top of shoulder to about half way down my upper arm. extremely red and super itchy.

My arm was extremely sore and red with a large bump..it then get better starting January 13 2021 I noticed the bump and red spot coming back it is now very large and swollen itchy and sore i have a headache and am very fatigue a week after

Swollen lymph node above my left clavicle, tender and warm. First felt when I woke up around 8:00 AM on 1/17/21.

One week after the shot (1-14-2021) Patient (19 y.o.)reported side pain and appeared constipated, Laxatives given along with Tylenol, on further assessment Patient was noted to have left leg redness and abdominal fullness. Dr. was updated and we had orders for close monitoring, the next day when she got up, her leg appeared better, and she had passed a small BM, but by lunch she had developed significant pain and edema in her left leg, and the color of her leg was reddened again. She was sent to the emergency room with her symptoms. She was admitted back to our facility yesterday, her diagnoses included Acute provoked left external illiac, femoral, popliteal, and peroneal DVT. Elevated Factor II levels, Elevated APC resistant, May-Thurner Syndrome, history of developmental disabilities, fecal impaction and urinary retention - suspected related to her fecal impaction. Vascular surgery was consulted, and pt. was started on a heparin drip, and mechanical thrombectomy was needed for both legs due to multiple clots. She was started on Eliquis and Plavix, and thigh high compression stockings were ordered, ace wraps being used until these are supplied. Her Fecal impaction was addressed also and the urinary retention resolved.

For two days after injection, I simply had regular, dull, pain in my arm from the injection. This got better and I had no other symptoms. One week from the date of my vaccine, I woke up with a swollen and red arm below the injection site. It was itchy and painful. This has persisted for two days and I saw a physician for it. We are currently monitoring the site for possible cellulitis.

10:00pm on 1/26/21 (day of vaccination): Fever over 100, severe chills. After 12:30 am on 1/27/21 and lasting all day: neck and back stiffness and severe pain, joint pain, Fever over 100, chills, fatigue, and swollen lymph node in axillary area. Fever and majority of symptoms subside with acetaminophen but fever and symptoms return when Tylenol wears off.

Sore arm (resolved), weakness, fatigue, racing heart, nasal congestion, swollen lymph nodes, severe sinus headache and pressure continuing past day 5.

Swelled lymph nodes in left neck and left axilla. Treatment-PCP notified. naproxen for discomfort and warm compresses applied to sites. Nodes still swelled, not as painful on 2/5/2021

Patient is a 19yo female presenting to the ED with chest pain. Patient received her second Moderna vaccine two days. Since then she has been having symptoms of chills and myalgias. This morning she had severe chest pain in the middle of her chest. It made it difficult to breathe. Patient had no side effects from 1st dose of vaccine and denies any symptoms prior to receiving 2nd dose.

Sore throat (difficulty swallowing), swollen glands, joint pain, low grade fever (99.8), sore arm, for 7 days. Day 9 delayed COVID arm with 8 x 8cm outer ring, and inner bullseye of 4cm x 3cm hot to touch, pain on site, swollen . Returned low grade fever on Day 15.

The site of the injection felt itchy for days following the injection. On February 12, I noticed an itchy bump on my right hip. The next morning, there were itchy, hard bumps on my feet and right ring finger. The bumps on my feet have become swollen and warm and seem to be growing larger, especially today on February 14. Two small bumps have also developed on my hands. I am not sure whether this is related to the vaccine, but it has become painful to walk.

I developed an initial fever of 101.2° and was completely bed bound, then that same initial day I began to develop extremely painful and unexplainable mouth sores and lesions. Some developed on my cheeks, some developed on my tongue and they were so painful that I could not eat, drink water, or even talk. I continued to spike fevers for an entire week without being able to control it. The pain was so unbearable and nothing was helping the pain go away, I am still unable to eat solid foods although I no longer have fevers. My throat also really hurt and my neck lymph nodes felt sore to the touch. The lesions in my mouth are beginning to heal but I am still bed bound and am trying to recover. Only thing I can bring myself to eat is chicken broth. I saw multiple doctors, not one of them was able to figure out the source of these awful lesions. They put me on acyclovir and cefuroximeacetil as an antibiotic.

SWELLING AND SECONDARY BACTERIAL INFECTION OF RIGHT ARM WITHIN WEEK OF ADMINISTRATION; TREATED SUCCESSFULLY WITH CIPROFLOXACIN AT EMERGENCY ROOM. WITHIN 1 WEEK OF RECEIVING VACCINE, PT NOTICED INCREASED WORK OF BREATHING AND PROCURED ALBUTEROL INHALER AFTER SEVERAL YEARS OF NO ASTHMA SYMPTOMS. SYMPTOMS WORSENED DAILY. SHE WAS SEEN @ CLINIC 02/13/2021 WITH ACUTE ASTHMA EXACERBATION: RX'D QVAR 80, ALBUTEROL NEBULIZER, SHORT-COURSE PREDNISONE, AND SINGULAIR. 02/14/21: ADMITTED TO HOSPITAL FOR WORSENING SYMPTOMS RELEASED AMA THE NEXT DAY. 02/20/21: URGENT CARE VISIT FOR WORSENING SYMPTOMS. RX FOR IPRATROPRIUM INHALER AND ZPACK 02/23/21: HOSPITAL ED FOR WORSENING SYMPTOMS; NOT ADMITTED

Approximately 36 hours after the second vaccine the patient began to experience palpitations, tachycardia, shortness of breath, dizziness and left arm/scapula pain.

Angioedema, Urticaria, hives, shortness of breath Developed facial swelling approx 3h after receipt of 1st-dose Moderna COVID-19 vaccine. Subsequently developed hives and trouble breathing.

The day of vaccination my top lip started to swell and small rashes formed on my arms, neck and butt around 8:30 pm. The following day my bottom lip started to swell and so did my left cheek at 8:30pm. Around 11:30 pm I started to develop a fever, feel soreness and weakness throughout my whole body, and a migraine. In the morning at around 8 am I noticed that I broke out in a severe rash all over my body. It has continues to spread all over.

My arm really hurts, it feels like I got beat with a bat. It swelled a little too and feels hard to touch. I cannot love my arm without it hurting. I?m also really tired

Syncopal Episode - VSS Fell from chair, hit L forehead. Ice applied, large swollen red knot noted. Medic called to ER for evaluation.

Swelling beneath left axilla following Moderna vaccine on03/29/21. Pt. first noted swelling 2 days ago worsening through the night. No known fever. Pt. also received tattoo to left forearm on 03/28/21. Modified activity for lifting.. Symptomatic care.

Patient is experiencing body aches and severe throat pain and vomiting for 6 days so far. 2 ER visits and 1 visit for family care doctor. Given IV fluids for dehydration and Toradol injections for throat pain and swelling 2 times. Her lymph nodes in throat are very swollen and swallowing is extremely painful.

"Alerted to reaction by vaccine administrative staff on 03/09/2021 after they had received a message from the patient's mother. Note that patient received dose on 01/01/2021 and had already cancelled her 2nd-dose appt. Per phone conversation with the patient: Approx 3h after receiving 1st dose Moderna COVID-19 vaccine developed facial swelling (more on the left side of her face). Next day, awoke with some difficulty breathing and hives. + difficulty swallowing. Self treated with ibuprofen and antihistamine without significant improvement. Saw PMD, who prescribed PO steroids. Sxs resolved approx 1.5 wks after onset. Did not require hospitalization. PMD rec'd that patient not receive 2nd dose."

fatigue; difficulty swallowing.; allergic reaction; chest pain; shortness of breath; not feeling good; Weakness in Lower half of body; Difficulty breathing, brain is foggy, swelling in throat, excessive sweating, puffy face,having difficulty talking and her face became puffy; Feverish; This spontaneous case was reported by a consumer and describes the occurrence of ANAPHYLACTIC REACTION (Difficulty breathing, brain is foggy, swelling in throat, excessive sweating, puffy face,having difficulty talking and her face became puffy), CHEST PAIN (chest pain), DYSPNOEA (shortness of breath) and FEELING ABNORMAL (not feeling good) in a 19-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 041L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. The patient's past medical history included No adverse event (No reported medical history). Concomitant products included ISOTRETINOIN (ACCUTANE) and ESCITALOPRAM OXALATE (LEXAPRO) for an unknown indication. On 19-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 19-Jan-2021, the patient experienced ANAPHYLACTIC REACTION (Difficulty breathing, brain is foggy, swelling in throat, excessive sweating, puffy face,having difficulty talking and her face became puffy) (seriousness criteria medically significant and life threatening), MUSCULAR WEAKNESS (Weakness in Lower half of body) and PYREXIA (Feverish). On 21-Jan-2021, the patient experienced CHEST PAIN (chest pain) (seriousness criterion medically significant), DYSPNOEA (shortness of breath) (seriousness criterion medically significant), FEELING ABNORMAL (not feeling good) (seriousness criterion medically significant) and HYPERSENSITIVITY (allergic reaction). On 22-Jan-2021, the patient experienced DYSPHAGIA (difficulty swallowing.). On an unknown date, the patient experienced FATIGUE (fatigue). At the time of the report, ANAPHYLACTIC REACTION (Difficulty breathing, brain is foggy, swelling in throat, excessive sweating, puffy face,having difficulty talking and her face became puffy), CHEST PAIN (chest pain), DYSPNOEA (shortness of breath), FEELING ABNORMAL (not feeling good), MUSCULAR WEAKNESS (Weakness in Lower half of body), HYPERSENSITIVITY (allergic reaction), DYSPHAGIA (difficulty swallowing.), FATIGUE (fatigue) and PYREXIA (Feverish) had resolved. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. Concomitant product included birth control. Treatment information included anti nausea pills, aspirin, epiPen, benadryl, tylenol, injection for breathing and surmonside. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

Two swollen supraclavicular lymph nodes on the side of injection (left clavicle). Spots at first were painful, moveable, and soft. It's been four weeks and they are still present, but with less pain and movement. They only shrink in size when taking ibuprofen, but swell again when the medicine wears off.

the patient unknowingly had COVID19 at the time of vaccination. on 4/13 the patient experienced non-lifethreatening facial swelling and sought medical care with facility on 4/15. the patient was prescribed a course of prednisone and she reports that worked to bring the swelling down. per the patient, the patient's allergist has recommended waiting 90 days to receive the second dose and has prescribed an epi-pen for when she does receive the second dose. She has been advised to receive the dose in a healthcare facility.

Systemic: Allergic: Itch Generalized-Medium, Systemic: Allergic: Rash Generalized-Medium, Systemic: Allergic: Swelling of Face/Eyes/Mouth/Tongue-Mild, Systemic: Chills-Mild, Systemic: Exhaustion/Lethargy-Mild, Systemic: Hypotension-Medium, Systemic: Shakiness-Medium, Systemic: Tachycardia-Mild, Systemic: Tingling (specify: facial area, extremities)-Medium, Additional Details: Patient had allergic reaction beginning around 10 minutes after Moderna vaccination. Patient has rash/hives on trunk, arms and legs. She stated she was lightheaded/dizzy, which lasted around 30 minutes. Her hands, arms, body had tremor and were shaky. She had blue/purple coloring of palms, which were cold and swollen. BP was 84/65 on my machine. HR was 110 bpm, minor lip swelling. Patient was given Benadryl oral 25 minutes post vaccine and EMS were called 35 minutes post vaccine due to concern.

chills and fever the night off, tired, the day after her armpit of the arm she was vaccinated in is red and swollen, it is painful,

I became very tired and had body aches two days after my second dose of the Moderna vaccine. After that, it had been about four days since I had received my second dose. I started to notice rashes appear all over my body. They were very itchy at times. So then I went to my local urgent care on May 4th, 2021 to see if they knew what was happening. They prescribed me Hydroxyzine for the itching and Prednisone for the swelling of the rashes. As of May 5th 2021, almost all of the rashes are gone thanks to the medication.

An itchy and sometimes tingly swollen welt/rash at the location of the injection. Firm to touch and about an inch and a half in diameter. Additionally a swollen lymph node along the collarbone.

Pt. c/o hives and swelling of entire right arm developing later the same day of her 2nd Moderna vaccine. By 5/5, she had wheezing, coughing, itchy throat and eyes, and redness of face. As of 5/7, she is still wheezing and has a bruise at the injection site. Was seen at an urgent care center and advised to take Benadryl. It is minimally helpful and wears off quickly and the symptoms return. Pt. is currently uninsured and was given information for low-cost clinics. She was advised to have wheezing evaluated.

At 10:00 pm I started with a stomach ache (12 hrs after my vaccine). By 10:05 pm I was experiencing nausea, vomiting and diarrhea. Within 10 minutes, my face had swollen up, my eyes were swollen and red, and my hands, feet and chest had hives. Paramedics were called and arrived 5 minutes later. At this time I was barely able to walk, was still vomiting and having diarrhea, and was shaking. They put me in the ambulance and took me to a 24hr emergency clinic. In the ambulance, I was given saline, epinephrine, Benadryl and nausea meds. I stayed under observation until 3 am. I was released to go home at that time. Since then I have only experienced weakness and nausea.

Approximately 1 week after vaccine administration in her L deltoid patient noticed two enlarged lymph nodes in her L axilla. When examined today (05/12/2021) nodes are mobile, nontender and approximately 1cm in diameter.

About 6-7 hours after receiving the vaccine, I started to develop hives around my body, including on feet, stomach, ears, face, back, and legs. I had fever and chills, muscle aches, joint pain, headaches, and nausea later that night as well. The next morning, my left eye was swollen, left side of tongue completely swollen, lips swollen, and left side of throat closed (anaphylaxis). I took prednisone, Benadryl, and Tylenol to relieve the symptoms, and the swelling around my left eye, tongue, throat, and lips went away. Throughout the day, more hives have developed around my body and face, including my right eye. I am continuing to take Benadryl and Tylenol and finish doses of prednisone. The fever and chills, muscles aches, joint pains, hives, headache, and nausea are still present.

Itchy, burning, and swollen. If I itched it it would get worse so I avoid touching. When showered I would let my arm stay under the warm/hot water. It would look better for a day or two and it would get worse. It?s been a few days that it healed.

Patient mother called the pharmacy and said her daughter (the patient) experienced face swelling a few hours after the vaccine. She called her doctor and they advised her to take benadryl. She called on 5/19/2021 to ask if her daughter can get a letter from the pharmacy stating that she s exempt from getting the COVID vaccine for school. Also, she stated her daughter is feeling better and swelling is going down, and her daughter did not have any other symptoms. I informed her that I can provide her with a letter saying that she cannot get the 2nd dose of Moderna vaccine due to allergic reaction but that might not exempt her from other covid vaccine.

The subject became symptomatic approximately 24 hours after her study injection. Symptoms included some swelling under her eyes, generalized body aches and apparently some hand swelling, as well as shortness of breath and stridor. She was given epi was given and EMS was called. Admission labs showed hypocalcemia and hypokalemia. She was treated with IV's and labs returned to normal limits, and she was given albuterol. She was hospitalized.

About 2 hours after the vaccine being administered, patient experienced hives, ger face became red and swollen, and she was itching all over her body. She went to the ER , her heart was racing, they gave her benadryl injectable. Soon after, she started to feel tired and sleepy, and during the next day she was feeling still tired. The day after, she is feeling much better, still experience a little bit of itchiness at forehead and arms, seldonly.

First dose of Moderna: received vaccine April 23,2021 woke up April 24th my lips were swollen, blue and itchy. I had hives all over. I called my aunt that?s a doctor she told me to take Benadryl which helped. The swelling on my lips lasted until April 27th, and only one side swelled up . 2nd dose of Moderna: I had a fever, chills, swollen lips, itchy tongue, my lips also turned blue. This time the opposite sides of my lip swelled up and it?s extremely painful when rubbed against. I can breathe so I?m not worried. Allergy medicine seems to help with the swelling and itchiness. My nose is stuffy and i have a lot of abdominal cramping.

Moderna COVID-19 Vaccine EUA Fever of 102.2, swollen face and eyes, cold sweats, diarrhea, and confusion. Lasted from the night I got the second dose (5/27) until today (5/29).

The patient got the injection around 11 AM and experience swelling of the lip and cheek at 6pm. Patient thought it was onset of a cold sore and followed up later after she was experiencing pain trying to chew. The doctors told her there was nothing they could give her and to monitor for severe anaphylaxis per patient mother.

At 2 PM on 6/6/2021 I received the second shot of the Moderna Covid-19 vaccine. At approximately 1 AM early morning of 6/7/2021 patient experienced Chest pain and shortness of breath. At approximately 4 AM I woke up and was itchy in several places on my body and saw rashes which were red and raised located on back of neck, both hands, both arms, her right hip behind both ears, left knee, right thigh and left shoulder, right upper mid-chest area to right side. After that took an immediate shower and then left to go to the Emergency Room and arrived approximately at 5:30 AM. ER Doctors gave Prednisone and Benadryl at 6:10 AM. After a few hours rashes appeared to start to leave.

Seen for OV 6/18/21 A week after second vaccine enlarged lymph node on back of neck base of skull. Pt to schedule follow up appt for lump.

Fever, chills and shaky muscles the night of my second dose. Three days later, I had swollen lips and lymph nodes as well as body aches and a closed throat. Took Benadryl and symptoms went away within a week.

Site: Redness at Injection Site-Medium, Systemic: Allergic: Swelling of Face / Eyes / Mouth / Tongue-Medium, Systemic: Lymph Node Swelling-Mild

I took my daughter to ER twice on July 7th and July 11th and she has been in the hospital ever since. They suspect GBS. She can?t walk, has extreme pain, and is struggling to understand what is happening to her. She was a healthy 19 year old woman jumping on a trampoline and enjoying her life as we hiked through the park just 2 weeks ago. Now she can not walk, has 80% paralysis and has pain that makes her cry constantly. As a reference she is a tough woman - she had her wisdom teeth removed and never used the pain medication they sent home with her. She is in the hospital with no clear path back to a normal life and all of the doctors implied that the most logical cause is the vaccine. She has insurance for the moment (through me) but she can?t work and my insurance may not renew. This will destroy her (and possibly me) financially if there is no help.

Chest pain Trouble breathing Fever Rash on arm around the place the shot was given Itching on hands and feet Swollen fingers Swollen tongue Swollen feet Swollen throat Dizziness Nausea Headache Diarrhea Stomach pain

Shot arm became itchy and small red bump formed. Over the past 24 hours, the bump grew and is still red and warm to the touch. Soreness throughout right arm where I got the shot.

One week after my shot my arm had became itchy and red. Now it is not itchy, but it is red and the swelling spot has grown from a small mosquito bite size to the size of my palm. Very warm to the touch and my right arm is sore.

35 minutes post vaccine, felt light-headed, dizzy, itchy throat, tingly body. O2 @ 2 L NC, lay down, drank water. VS monitored- stable VS. 18:45 continue with symptoms, throat scratchy, face swelling- Benadryl 25 mg PO. By 19:30 she was improved and discharged home to mom. 1/8/21- work up a bit dizzy, nausea. 1/11/21-still with nausea, dizzy- Referred to manager to complete assessment for COVID symptoms. 1/14/21- Per PMD, getting COVID tested, quarantine for 10 days.

Symptoms: Chills, cold sweats, enlarged lymph nodes, enlarged tonsils, mild fever, trouble sleeping, headaches, muscle ache, muscle fatigue, muscle spasms, weakness, dehydration. Chills and cold sweats occurred several hours after receiving the vaccine, other symptoms progressed over 2 days.

Swollen and sore axillary lymph node about the size of a grape in the left arm. Onset on 01/27/2021, 8 days after vaccination. On the day of onset, I felt very fatigued, lethargic, and weak.

Ongoing chills, nausea, diarrhea, fatigue and malaise. On the 7th day after the vaccine was administered, the patient also developed injection site erythema, swelling and tenderness; left supraclavicular and left axillary lymphadenopathy outcome pending

On the night I received the COVID-19 vaccine, I had a fever that went up to 103 degrees Fahrenheit. In the morning 24 hours after I had the second dose of the COVID-19 vaccine, I felt a little better from the night's fever and ate instant ramen, oranges, acetaminophen, and a vitamin C tablet. This was at about 8:45 AM. A few minutes or a minute after I swallowed the acetaminophen and vitamin C, I got a severe allergic reaction that led to me going to the Emergency Room. I have eaten these things before and am not allergic to acetaminophen, vitamin C, or anything in the instant ramen. The reaction was first felt by a shortness of breath and I could barely breath. Then, hives started to form on my face and my lips and face became extremely swollen. I then ended up throwing up after my mom gave be a Benadryl pill and I drank another Benadryl after. My face had become less swollen but it was still difficult to breath and hives started to form all over my body so we decided to rush to the Emergency Room. We got to the Emergency Room at about 9:30 AM and the hives on my body were worse. They were able to calm down the reaction by giving me more Benadryl through an IV and steroids. They knew I had the second dose of the vaccine so they did not give me anything that would suppress my immune system. Timewise, it could be the acetaminophen, but I have taken acetaminophen in the past many times before without a reaction.

I noticed a hard lump on the right side of my neck, in which I assume to be a lymph node. I got my shot in my right arm as well.

Swelling of arm week after vaccine. Red, swollen lump on left arm. As well as swollen lymph ones under left armpit. The day after vaccine, my arm had the normal inflammation related to the vaccine. It went away after 4 days. A few days after my arm started to become itchy. It has been itchy since. On 2/11, my arm swelled up again and became red around the injection site and hard and warm to touch.

Local Redness of Swelling 50 to 120 mm, but not below the elbow. Itching but no other symptoms reported. 50mgs diphenhydramine given IM Right Arm. Observation started for 60 mins. All symptoms subsided.

My entire face was covered with hives. Within 2 hours of the vaccine I developed hives to the bilateral aspect of my face, forehead, cheeks and eyelids. My hives were itchy and red and I have never experienced this before. I did not consume any new food or use any new products. I took Benadryl for the itchiness. I had a telemedicine visit and I also had a Covid-19 test which was negative. I called health and also reported this adverse reaction. Moreover, I had no reaction to my second dose which was on 01-28-2021.

I developed a very large, swollen lymph node under my left axillary. I have never before had a swollen lymph node in either axillary regions of my arm. It was very painful, I could barely put my arm down because of the pressure of it pressing against the side of my body at rest. It has gotten better, there isn?t as much pain but it is still uncomfortable. The lymph node was/is palpable, and hurt upon touch and rest. The pain was an 7/10, but has now gone down to a 2/10. My arm is also still sore from the injection site, but it is not bad.

Flushing, shortness of breath, fast heart rate, sweating, nausea? 10 minutes after-30 minutes after, took Benadryl and tylenol Fatigue, brain fog, body aches, shoulder and elbow pain, sensitive to touch at injection site, red raised site about a size of quarter- 30 min after-36 hrs after, no treatment Intermittent fever in first 36 hrs

1 week after recieving the first shot of the Moderna vaccine, I bumped my right arm about 2 inches below the injection site. Throughout the course of the day, my arm progressively became swollen and sore, to the point where I couldn't move it much or sleep on it. The next day it got progressively better on its own, and then I began taking an antibiotic prescribed by my doctor that helped it heal the rest of the way. I'm not positive if the rest of the healing was on its own, or directly because of the antibiotic.

Localized swelling since injection first administered. About 7-8 days later redness, itching, and fever began at sight of injection swelling.

Painful swelling of toes. 3 weeks so far, does not show signs of stopping. Taking naproxen to help. Difficult to walk.

Left arm swollen, red, hot, itchy, fever of 100.4, 1 day, generally felt bad. The redness, swelling, itchy, and feeling bad lasted 2 weeks. Treated with benadryl and ibuprohin.

Moderna COVID-19 Vaccine EUA bad rash all over body (hives) sore throat fatigue swollen fingers, wrists, eyes, ankles

Exactly eight days after taking the vaccine my arm became really sore again and the lymph nodes under my arm swelled up and are painful to the touch. I have a rash on my arm like a red welt, but it does not itch, it is just sore. On the affected arm my hand shakes and it feels weaker than my other arm.

Awoke in the middle of the night to mild/moderate anaphylaxis - tingling throat and tongue, swelling of throat and tongue, difficulty breathing, nausea, gagging, diarrhea - lasting for about 30 minutes - all symptoms occurred at the same time

Fever started at 11:30pm 4/6/2021. Fever ~100 degrees F. Had chills and couldn't get warm, then was hot and drenched in sweat. Repeated all throughout the night (Hot/cold). Took 500mg Tylenol at 12am that night. Woke up at 2am with a ~102.4 F fever. Took another Tylenol. Got out of bed around 8am 4/7 drenched in sweat. Felt nauseous and vomited almost right away and couldn't stop for a few minutes. Still had around 102 F so took 2 more Tylenols. Throughout that night and until Friday, I was achy all over my body. Also, lymph node under left arm pit was swollen and was sore along with my left arm. Throughout the day on 4/7, laid in bed trying to get rest and too nauseous to eat anything other than some cereal in the morning and plain noodles later in the day. Took another Tylenol in the afternoon because I was still staying at 102 F fever. Was slightly dizzy when standing up or moving too fast. I slept the next night and felt fine 4/8 morning (no fever), but felt worse as the day went on, aching everywhere and feeling more and more dizzy. Friday 4/9, I woke up in the morning and when I first started walking, I fell on the floor because of extreme dizziness. The whole day I was extremely dizzy and I've never had vertigo before, but it seemed like that based on explanations of it. Also had painful headache every time I stood up, but was fine when I wasn't moving. The next day it was mild dizziness and completely gone the day after that. Also, Thursday 4/8 around 7:30pm, I noticed I had hives on the back of my right hand. Not 100% sure if it's due to the vaccine, but I'm not sure what else would have caused it and it's worth noting. It was gone the next day.

DAY AFTER 1ST DOSE MODERNA COVID VACCINE HAD FEVER AND NAUSEA, NONPRODUCTIVE COUGH (MUCOUS) AND PLEURITIC CHEST PAIN. SYMPTOMS CONTINUED 5 DAYS.

Around 9:45p my face and neck broke out in hives, swelled up, was extremely itchy, and hot. Shortly after it became hard to swallow as my throat was closing. I went to Emergency Department around 10p. The doctors administered Epinephrine (via Epi Pen) and Pepcid through an IV. I was prescribed an Epi Pen as well as Claritin and Omeprazole for 14 days.

After first vaccine: History: Moderna COVID vaccine on 3/11/2021. Arm soreness over the first day or two but nothing else that really struck her. A few days after she started to notice axillary pain that progressed up her right neck and down to her right hand. She saw a physician who thought she was having nerve pain brought on by the vaccine. Around the 18th she started to feel a snapping pain in her wrist. Went to ED on the 20th because she started to have arm shaking, she was given ativan, her arm shaking stopped and they discharged her home. That evening her fingers felt clenched. On the 21st she woke up in the morning, went to urinate and dropped to the floor because her legs felt like jello and felt like they kept giving out. They initially thought the ativan was just making her feel out of it. They waited until the evening but then needed to go to the ED. The concern was GBS and transverse myelitis. They ate dinner and decided to drive to ED, on the drive she was kind of falling asleep periodically. Then she suddenly couldn't lift her water bottle. She started to be completely out of it, Mom says she wasn't responding. Pt says that she felt like she knew what was going on, felt a little out of body and wasn't quite responding. Mom couldn't get her out of the car, she was carried into the ED and at that point she started to recover a little bit more. About 10 minutes later she started to feel better. She was admitted because she was still having trouble walking. In the hospital she had a normal CT head and video EEG but she didn't have any events while on the monitor. Discharged home the following day with the diagnosis of functional neurologic disorder and instructions to establish care with an adult PCP. They advised considering CBT as well. Since discharge her legs feels tired, going up the stairs feels much harder than it should. She has not had any falls and no longer feels like she is going to fall. She follows with a therapist, has had dissociative episodes and panic attacks in the past. Assessment: 20 YOF with PMH of panic attack, POTS, IDA and benign heart murmur who developed weakness of b/l LE and altered consciousness approximately 10 days after her first dose of Moderna COVID vaccine. Also had an episode of unilateral arm shaking the day prior that resolved with ativan in the ED. At this point unclear if directly related to vaccination. Differential includes mild Guillain-Barre 2/2 previous infection or vaccination, stress reaction/anxiety, POTS complication, myasthenia gravis, tick bite, infection, heavy metal poisoning, B12 deficiency, seizure disorder, atypical migraine. Functional Neurologic Disorder diagnosed by neurology after overnight admission for video EEG which captured no events. CT head also WNL per neurology discharge summary. Neurologic exam today WNL. After Second Vaccine: History: She had her 2nd vaccine on 4/15 (6 days ago). Had vaccine in right arm again, she did have some arm pain again. She had coffee without breakfast in the morning. Had finished her first virtual class, went to the restroom during her second class, felt strangely in the restroom, went back to her room. She then passed out. Her fall was unwitnessed. She called to her roommate when she came to but her roommate hadn't heard the fall. She thinks she was only out for a few seconds but cannot be sure. Called her Mom who advised her to eat something so she ate an orange sitting on the floor. She got up to make herself breakfast and she passed out again. Again unwitnessed but patient thinks it was very fast. She crawled over to the couch, sat on the couch for for 15 minutes then felt fine for the rest of the day. She did not feel nauseous at all. She denies palpitations, difficulty breathing and chest pain. Today in office after orthostatics and blood draw she fainted again, only out for seconds. BP elevated immediately after the event but WNL minutes later. These syncopal episodes reminded her of her syncopal episodes with IDA and POTS. They do not feel like the episode after the first vaccine when she lost feeling in her legs and was very out of it. She feels like her arm pain from the first vaccine never fully resolved. After the arm pain worsened from the 2nd shot she tried a 3 day course of aleve to see if that helped things. At this point it is mostly just her right wrist that is painful. Overall feels more localized to wrist than prior. She has since stopped the aleve, last was last night. She has not noticed redness or swelling in wrist or arm. LMP was 4/2-4/6. She went almost a year without menses so stopped her OCP, but her menses have returned recently and she has restarted OCP. Assessment: Right arm pain persisted from the first vaccination but otherwise sx had resolved. She got 2nd vaccination on 4/15, only arm pain but yesterday had 2 brief syncopal events and one today in the office. Orthostatic BPs not completely convincing for orthostatic hypotension today.

Patient received the vaccine on Thursday, 4/22/21. Patient started having warmth and redness at injection site on Tuesday, 4/27/21. Patient hasn't take any over-the-counter medications. Patient stated the the swelling has increased. Patient stated the pain has stayed the same. Patient reported side effect to pharmacy on Friday, 4/30/21

Patient received vaccine 5/2/21. Patient went home and noticed swelling, redness, bruising, burning, and numbness (to end of fingertips) in the injected arm. Reported severe dizziness and passed out. She also experienced increased heart rate/blood pressure. On 5/3/21, while experiencing the same symptoms, went to nearby medical facility (urgent care) where she was told that a nerve had been hit or bone had been hit. She was sent home with a heart monitor, in a sling, and was told to stay home from work for 2 days. Her symptoms continued through the day, continuing into 5/4/21. As of 6pm 5/4/21 she is going to go to an emergency room.

After the first shot, April 8th, about two weeks of receiving the first vaccine, I had noticed a bump of my left side collar bone and I got an ultra sound for and it was just an enlarged lymph node. A day after the second vaccine, May 7th, I noticed that the shot area was red, warm and enlarged, with itchiness. Also the left side of my neck where the nodes are, is swelled and tender to the touch.

My arm got red and swollen about 30 mins after. It's been like that for like a week and a half now. It's less red some days and more red others. It has not spread

one episode of blood tinged stool after 1st vaccine then 3 days of bloody stool following second dose

13 minutes after receiving first dose of Moderna Vaccination as patient was waiting observation time she fell out of her chair when she lost consciousness and hit her head on the floor. When she regained consciousness she asked what happened and she was told what happened as described above. Then she states that "this has happened before when she sees other people get shots". She was alert and oriented to person, place, and time. Swelling appeared on her head above her right eye. Blood preasure reading 76/45 pulse 51 respirations 20 and patient states that she is "ok". Due to the fact that she lost consciousness and hit her head on the floor the ambulance was called. Prior to ambulance arrival blood pressure recheck was 125/93 pulse 91.Patient was talking on the phone to her mother when ambulance arrived. Patient was taken to local ER by EMS for further evaluation.

Pt presented with 2-3 days of right-sided chest pain and dyspnea. CT demonstrates bilateral PE. Pt prescribed apixaban.

Intermittent lymphadenopathy of the upper body (pre- and post auricular, submental, cervical, axillary, occipital). Fatigue, ear pain, injection site pain still present at day of report. Treatment for intermittent pain has been NSAIDs PRN and Wellbutrin for the fatigue.

Tingling and swelling to face and hands. Facial flushing to bilateral cheeks. Difficulty swallowing. Patient received Benadryl PO, Pepcid PO, and Decadron Injection for reaction.

Headache onset 3-4 days after vaccine on 4/27/21. Subsequently developed visual changes (right homonymous hemianopsia/visual field cut) on 5/23/21 and presented to ED, diagnosed with cerebral venous thrombosis (left transverse, sigmoid and internal jugular thrombosis). On initial labs also had thrombocytopenia and mild leukocytosis.

one day 5 feet swelled with a red, itchy rash and were painful to stand on. This lasted 5 days. Currently, lymph nodes in neck are swollen and painful.

my symptoms included: migraine, nausea, diarrhea, swollen lymph nodes on same side where injection site is, induced period. I am at home experiencing these currently and am asking if i should see a health professional?

Systemic: Allergic: Difficulty Breathing-Medium, Systemic: Allergic: Difficulty Swallowing, Throat Tightness-Medium, Systemic: Allergic: Swelling of Face / Eyes / Mouth / Tongue-Medium, Systemic: Flushed / Sweating-Medium, Systemic: Hypertension-Medium, Additional Details: patient was given shot. about 5 minutes after she was complaining of chest tightness and difficulty breathing. i took BP at 208pm 177/22 - pulse 99. I spoke to the patient't nephrology nurse, she said patient has many allergies and to start our protocol. At 223pm BP was assesed with a manual device and still high at 170/120, patient still complaining of difficulty breathing and chest tightness, 1 dose of epinephrine 0.3mg was administered intramuscularly in left thigh.

Pain and tenderness in the surrounding area of the injection site. The muscle soreness in the arm started about an hour after receiving the vaccine and worsened into the evening. The tenderness mostly went away by the next morning, the worst of it being the evening of the dosage. Tenderness and slight swelling to the lymph nodes in the same arm as the injection site started in the early afternoon the same day as the dosage. This tenderness lasted for about 5 days. Experienced fatigue and a mild headache the evening of the dosage.

Patient presented 0n 5/25/21 with chest pain, shortness of breath, nausea and headache. Work-up showed pericardial effusion with pericarditis. Drain placed. Patient responded to ibuprofen and colchicine therapy. Patient unsure of dates of vaccination. Stated April-May 2021.

Patient received 2nd dose of Moderna vaccine today (6/12/21) and experienced shortness of breath, raspy voice, visible redness/swelling to face, difficulty speaking approximately 1-1.5 hours post vaccination. She received the 1st Moderna dose on 5/14/21 and did not experience any significant adverse events (only experienced arm pain, redness/swelling at site of injection). Administered epi 0.3mg IM x1, diphenhydramine 50mg IV x1, Solu-Medrol 125mg IV x1, famotidine 20mg IV x1, albuterol 5mg neb x1, and NS 1L bolus for anaphylaxis treatment in the ED. Also O2 4L/min per oxymask.

angioedema with need for epinephrine and transportation via 911 to local ER. Additional unknown treatment provided at ED

having a systemic reaction to her second dose received on 6/16/21 ? She is swollen head to toe and at the urgent treatment center

Patient comes in today concerned about a lump she found in her left axilla. She first noticed her left axilla was swollen and tender yesterday. She has gotten cysts and acne in armpit area before, but this feels different and nothing is seen externally like it normally would be with a cyst. Hasn't noticed any other lumps anywhere else. Got vaccine in left arm one week ago on 06/21. Left axilla appeared mildly swollen/bulging over bra compared to right axilla. Some scarring from previous acne and cysts was noted in the left axilla, but no active lesions were seen. Two lymph nodes were enlarged and palpable. One was 1/2 cm in diameter, tender, and mobile. The second was just superior to it along the axillary chain and was ~3 mm in diameter, mobile, and tender. Right axillary was unremarkable. No lymphadenopathy was noted in the right axilla or any of the lymph node chains on the right side of the neck.

LT arm got swollen Friday morning and throughout the day it started to increase. It felt hot with a sting to it. Saturday AM It was hard to breath and I was unable to take deep breaths since I felt like my inside were really swollen/Inflamed. Sunday AM the swollen had got down leaving a bruise as big as the inflammation had been.

One week after the first dose of the vaccine I started to get hives that spread all over my legs. The next day the rash was on my stomach. Every day they went from the soles of my feet and worked their way up my body until it reaches the palms of my hands. After this point I have been experiencing facial swelling. After the second dose the hives started again but it was much worse. It started the day after and I also had swelling in my face and lips. I have been referred to an immunologist. I still have hives every day after five months. They are mostly on my legs and thighs. They are big raised splotches which cover large areas. I have never had them on my face since the day after the second dose. I have taken Steroids and I still take Zyrtec every day. It is extremely itchy which was not helped by a topical cream. I also take anxiety medication so that I can sleep. Dose 2: 02/05/2021 LOT#012M20A

3 days after second Covid 19 vaccine, June 11, had one nose bleed that bled "a lot"- was bleeding out the front of the nose and just stopped on its own without any treatment. Started back up a week later with usually 2-3 times per day average time it lasts 10-15 minutes. After about 3 days she stopped her Zyrtec and Flonase to see if it would help, it didn't seem to help. She blows her nose, and will get out a larger clot- now the bleeds just fill up the nostril- has a big scab there. She does have a large scab in the nose. Right nostril only. Remote history of nose bleeds- however only 2 times previously- around 7/8 years old related to trauma/dry nostrils-

While receiving my second shot, a drop of the vaccine liquid came into contact with my arm, dripping down. I brushed it off, as well as the pharmacist. A day later the vaccination site started to hurt, which was expected but also itch. On Thursday, two days after I received my shot, my friends pointed out that my arm is in hives, red, and swollen. My arm is still in hives, and itches like crazy. It looks like an allergic reaction. I have pictures

The effects began with pain and inflammation in my right foot on July 4th. The pain and inflammation later escalated to my right arm, and thus I could not move them much. I visited a clinic on July 6th to no avail, and was referred to the hospital for testing. I visited a Medical Center on July 8th and received blood tests, x-rays, and ultrasounds. The tests all came back clear. I was prescribed naproxen for the inflammation. The next day, July 9th, my left foot was then inflamed and painful. I visited another physician on July 13th for a second opinion, and was prescribed furosemide as they had told me I had edema in my feet. On the evening of July 14th, I had begun to get a sharp pain in my right hip and thigh. The pain soon escalated well into midnight (July 15), and at that point, I could no longer move without a shooting pain that was unbearable. I visited the Hospital the same day, and again received multiple tests, including blood, ultrasound, and x-rays. I was there until the next day, and was given an anti-inflammatory shot, and was told to continue to take the naproxen for the rest of the dosage. As of today, July 29th, my swelling and pain have mostly gone down in my feet and arm, but I continue to have flare-ups of pain in the joints, and I now have pain and inflammation in my right knee. Any sort of joint inflammation was rare for me before I was vaccinated.

Started with arm pain, then lymph nodes in armpit were swollen and arm pain increased, could barely move arm because of pain, nausea and vomiting, chills and fever of 100.9, injection site the size of a baseball almost 48 hours after injection, super fatigued

Fever greater than 100 degrees F, full body muscle aches, chills, sore throat, tender armpit (left)- 12/27/2020 (all day) Itchy, blanched, swollen, hard, warm patch on left arm 4.5" x 3" with surrounding redness and tender armpit- 01/02/2021- present

patient experienced rash post vaccination. patient also has raised red welt on arm that is still present 1 week post vaccination and has not improved. patient does report pain in the area but states that it is warm to the touch. patient continue to monitor for resolution and will update staff. patient stated she took advil - for headache but did not see improvement in arm redness. patient declined medical attention from the emergency room today.

Vaccine was administered 12/30/2020 and as of 930am 12/31 I was throwing up and running a fever. I left work at 10:30 after realizing how bad I felt and went home. I slept for roughly five hours, from 11am to 3:30ish and then continued to throw up. I could not life my arm past my chest because it was so swollen and sore. I stayed at home and skipped new year's, going back to sleep around 1030pm. It was not fun

started with swelling at the hands and tingling, she then progressed to flush face with swollen lips and eyelides

Pt reported that at about 7pm the day of her vaccine she developed a rash on her left arm/leg. It was itchy and so she took a Benadryl. She said her "throat felt thicker" but the Benadryl helped. She went to sleep and was fine. When she woke up the next morning on 1-6-2021 she reported the rash had spread. When she got to work and found me about 9:30 am to ask if that was normal I encouraged her to call her PCP and take a Benadryl. At that time she was having no difficulty breathing. She chose to call her PCP and not take a Benadryl as it makes her sleepy. After she called her PCP she ended up leaving work. I found out later that her breathing had become labored and her neck/throat was starting to swell. Per her report, her PCP gave her epi and steroids, and R/X her an epi pen. She took her medicine and Benadryl around the clock and returned to work on 1-8-2021. When I spoke to her on that day she stated all of her symptoms had resolved, but her lymph nodes in her neck were still a little swollen.

Approx. 1.5 hours after vaccination she returned to the COVID site and reported HA, L arm numbness. The RN noted "A/O, VSS, site w/o redness, L arm swollen, can move arm. pulse strong, cap refill WNL, skin W&D. Reports nausea, released with dad to home." Pt was recommended to go to the ED or urgent care with any worsening symptoms, home with family.

Patient stated: "I had a dull headache beginning the evening that I received my vaccination. The following day I had a more severe headache and extreme fatigue. I treated my headache with Tylenol and slept most of the day. Two days after I received my vaccine, my face and neck began to swell and I still had a severe headache and fatigue, which I treated with Tylenol and Benedryl. The Benedryl decreased the swelling in my face and neck and when I woke up on the third day, my headache had resolved. I felt fatigued on the third day, but by the evening, all of my symptoms had resolved."

She reports that the first 2 days after her vaccine her arm was red, swollen and sore then resolved. She now reports that starting around 6-7 days after the vaccine she developed redness, itchy, swelling and soreness at the site. She also has body aches at this time

Pt stated that bruising started almost right off on 1/6/21 but itchiness redness and swelling started approximately a week later on 1/13/21.

Pt noticed itchiness and small bumps covering both forearms in early AM on 1/15, arms proceeded to worsen in redness, slight swelling with bumpiness around the edges, pt took 20 mg of prednisone around noon on 1/15. Pt woke up on 1/16 with rash now in right inner thigh, palm sized, as morning progressed pt noticed rash on top of butt/ lower back, extending up into the armpits on both arms, and on feet. Pt was in a lot of pain, pt took a hot bath, 40 mg of prednisone and 25 mg Benadryl. Pt took 50 mg of Benadryl night of 1/16. Pt awoke on 1/17 with worsened symptoms, pt repeated doses from 1/16.

01/12/21: Severe fatigue and brain fog 01/17/21: Pharyngitis of unknown cause. Fever over 102F, bilaterally swollen tonsils with white coating, bilaterally swollen lymph nodes in the neck, headache, fatigue. Initially prescribed Penicillin 500mg TID x 7 days (Telehealth). After day 3, symptoms continued to get worse. Strep test, Flu test, and COVID-19 tests were all negative. Prescribed Prednisone 40mg x 7 days. Symptoms began to subside on 01/21/21. Cause still unknown - possible viral infection (CMV, EBV). 01/21/21: Swollen, red rash began to develop at injection site. Subsided without treatment within 24 hours.

Dizziness Weakness Chills Body aches High heart rate Body shaking Migraine Arm swelling Hot at ejection site Nausea

Started to feel sx on 1/24 with nausea, fatigue, feeling of warmth, dry mouth, and her face and eyes were swollen. The injection site was red, hot, throbbing and the size of a tennis ball. On 1/25 she was congested, had a headache and the injection site was red, hot, sore to the touch and sensitive. Most likely is an allergic reaction with facial swelling and local reaction, treated with Benadryl Motrin and add Pepcid or Zyrtec. On 1/27 she was better with no fever x > 24 hours and less fatigue. No body aches and no trouble breathing.

Three majorly swollen lymph nodes in armpit of arm that received the vaccination. I noticed this reaction a couple of days after and contacted my PCP. She encouraged me to come in. She ordered an ultrasound of the nodes. Nodes showed no malignancy. Order to follow up in 3-6 months. Nodes are still currently present, but seem to be reducing in size. Second vaccination dose given 1/21/21 on left arm. No nodes in left armpit to date.

About 3-4 hours after the injection was given, my left arm began to hurt at the sight of the injection. It was sore red and beginning to swell. After a couple more hours it was difficult to even move my arm; it felt as if my tricep was almost entirely immobilized. These symptoms persisted for about three days, with increasingly less intensity, and after the fourth day, I had no adverse symptoms. Exactly six days after receiving the vaccine, the area where the injection was given (tricep) began to feel itchy. When I tried to scratch it, the itch was not relieved but only worsened and began to swell and turn red. By the following day (7 days after injection), the site of injection and area surrounding the site of injection (about 6 inches along my upper and 3-4 inches in width) had swelled up more and was significantly more inflamed than my opposite arm which hadn't changed at all. It had a similar swelling, itch, and pain to the sensation one experiences after getting bitten by a mosquito, but in this case a very very large mosquito bite. By the evening of the seventh day, I began feeling very fatigued both mentally and physically and felt very subtle body aches that usually signal the early signs of a fever (at least for me). Upon feeling feverish symptoms I made a drink of turmeric and ginger root powder with honey and laid down for about an hour in an attempt to rest. After an hour, the body aches and fatigue lessened in intensity but my arm was still swelling and now feeling hot in temperature. The itching was unbearable. I went to go take a warm shower later that night and started to feel a mixture of pressure and pain traveling up my arm and into my chest. I began feeling my lymph nodes on the left side of my breast to find that a lymph node in my armpit and another one on the side of my breast had enlarged to about two inches in diameter. They were painful to the touch and noticeably sore when left untouched. These symptoms persisted with no change for about 2 days. After two days, the swelling and itching in my arm went away but my lymph nodes were still inflamed. They did not reduce in size or in pain until about 7 days after the first signs of these symptoms. After a week all symptoms went away.

After the shot, my arm was swollen for 3 days and a small rash but it went away. Then, on Feb 13th a rash started to reappear that was warm to the touch and itchy and burning. I applied cortisone but rash on injection site kept growing. On Feb 14th, I woke up and rash was a bit smaller but every two hours I would have a tingling sensation like when your foot falls asleep but it went up my shoulder and back area up to my neck and occurred every 2 hours. I then was advised to take claratin, add more cortisone, and take Benadryl as well. The itchiness stoped. My rash is still there but it?s very light compared to feb 13th.

Pain under the left arm in armpit - suspected swollen lymph node. Tender to the touch, but does not limit daily activity. Noticed around 10:00pm on February 21, EST. Symptoms still occurring 24 hours later.

Numbness in neck began within 5 minutes of injection. 10 minutes later she started have difficulty with exhalation, tightness in the chest, and sensation of neck swelling. Patient was given 0.5 mL of epinephrine and EMS was called. Patient began to improve within 5 minutes of epinephrine injection. She refused to go to the ER. She was given 25 mg of Benadryl and was monitored for 20 minutes before going home with a friend picked her up. Patient signed an AMA for both the EMS and clinic.

On Day 7, I noticed a large swollen lump where the vaccine was injected. It was red, itchy, and hot. Most of the swelling went down after 24 hours, but 4 days later I still have a very large rash that extends from my shoulder to my elbow. It is red and has clear borders. It is still itchy and slightly warm.

PT WAS GIVEN VACCINE ON 2/27/2021 AND BEGAN HAVING SYMPTOMS ON 3/5/2021. PT ARM BEGAN HURTING AGAIN , ARM WAS RED WITH A KNOT AND WAS WARM TO TOUCH. ALSO HAVING PAIN THAT GOES DOWN ARM. SYMPTOMS ARE SOMEWHAT BETTER TODAY.

Congestion; swelling of face (especially around eyes) and neck/throat area; sore throat; fatigue; Benadryl taken (2 - 25mg pills)

Intense hives that developed over 48 hours into a rash of hundreds of hives on bottom of feet, tops of feet, ankles, back of calves, inner thighs, and under arms near biceps. Hives were symmetrical in nature and mirrored a ?covid rash? or urticaria. Swelling intensified even while on Benadryl. Only steroid began to help diminish redness after 24 hours on 80mg of prednisone. Began 3/10, worsened exponentially until taking prednisone on 3/13. Now (3/14) healing but still experiencing itchiness and red bumps.

The day of the shot I experienced a moderate headache throughout the evening as well as soreness at the injection site. The day after I received the shot I experienced severe muscle fatigue and a red rash, bruising, and swelling around the injection site.

Hives on arms and chest. Swelling and difficult breathing. 24 hours after injection. Headache, fatigue, flu like symptoms.

Approximately 12 hours after the event, I had throat swelling, chills, sweats, temperature of 102.5, headache, muscle soreness, dizziness, lightheadedness. Onset was over the course of about 1 hour. I had previously taken part in the double-blinded Astrazeneca in COVID-19 trials (meaning I did not know I was vaccinated) in November 2019, so the nurse told me that the response could really be from anything: partly due to some interaction between the vaccines, allergy, and/or already producing antibodies. I was unblinded and told I was given the Astrazeneca vaccine. Interestingly, I had none of these responses to just the Astrazeneca vaccines, just a bit of soreness after the first one. I have never had such a strong response, and I believe this is the highest my temperature has ever been, and my lymph nodes are still swollen. I am much better now; however, even last night and this morning, I was feeling unwell.

First day I had immediate swelling at the injection site, red circle form around the site of injection following up with an itch that lasted for 3 days. Along on those immediate symptoms I got the injection on my right arm and I experienced pain shooting up from my right arm into my neck and currently still have those pains from time to time when I move my right arm at an elevated angle. Day 4 of the vaccine I woke up one morning with swollen glands, congestion, swollen nasal glands, low grade fever of 100 degree F, very itchy irritated throat and hard to swallow, visited a clinic to see if I possibly had flu or strep but all my test results returned negative, also I had a covid test done and it was negative, I have never contracted covid 19 prior to vaccine and current day. Additionally, symptoms of congestion worsened and I am now experiencing some laryngitis due to the swelling of my lymph nodes, only sinus medication lessens the congestion to manage, I feel very fatigue, and experiencing some migraines. Today only marks 1 weeks since the vaccine

Within 30 min of the shot, my arm began to swell and itch. My face and some part of my body began to itch as well. Within the next hour, my jaw began to lock and my throat began to burn/tighten. Within this timespan, my body, especially my back began to ache as well as my chest feeling tight. After three hours, I went to the on-campus clinic and they gave me 50mg of Benadryl.

12 hours after injection there was increase swelling around the injection site and spreading into the Lt shoulder and upper back. Nausea, tightness in left neck and left upper back with swelling. Went to bed with ibuprofen and ice on swelling. Woke up 18 hours (5am) feeling sweating, difficult breathing, chest was tight with more swelling in left arm and left upper back. Got up to ask for help and fainted. Called father, mother we checked blood pressure was low (98/40), and was heart rate was low (46). Got her sitting up and blow pressure and heart rate returned to normal.

Around the time of receiving the first dose, I began experiencing hives in a linear pattern. I have been getting hives everyday since I got the shot in my thighs, chest, abdomen, arms, and back. Begins by feeling the urge to itch and once I start itching, raised bumps in a linear pattern will appear every where. Symptoms are only alleviated by taking Zyrtec daily. If I go more than one day without taking a Zyrtec, I begin to break out in hives at random time throughout the day every day. I have no previous allergies to food, no changes in my lifestyle or diet either.

Severe tiredness and fatigue, a bit lightheaded. Was not able to get out of bed for the most of yesterday. Left arm was very swollen, simply moving it was painful.

I concluded my menstrual cycle a few day before the vaccine and two weeks after the vaccine I began my menstrual cycle again. I?m not sure it?s related to the vaccine but it has never happened to me before. So I thought it would be best to report since if heard similar things from other women. It?s heavier than usual and more painful. Also I had pain in my left armpit that went away after a few days that started about a week before my menstrual cycle. I?m guessing it was swollen lymph nodes due to the vaccine because I have seen other women report that as well.

Rash on finger, toes that spread to hands, feet. Immediately very itchy then swelling worsened and heels were painful when standing. Came to clinic on day 3; diagnosed with erythema multiform. Treated with prednisone x 4 days; follow up next day to review lab which only showed mild ESR elevation and improvement of symptoms.

Dermatitis on the right lateral side of the deltoid the following day after the vaccine was given. Rash continued to expand, swollen shoulder, was red, and sore. Rash eventually went away after 5-7 days without any topical creams/ medication. Arm soreness went away after 2 days.

Had all the regular symptoms the day after the second dose such as headache, nausea, bodyache, fever, etc. Two days after vaccine I woke up with hives on both forearms and a little puffiness under my right eye. Three days after I woke up and my right eye and cheek were super puffy and I had a rash on my face that was red and blotchy and itchy. It is now four days later and hives and face rash still persist but due to medications don't seem to be getting worse.

Caller states she received her second dose of Modenra on 4/14/2021 and on 4/15/2021 the area became red, sore and swollen. Caller does not believe it is warm to touch at this time. Caller states it seems to be gettig "redder", advised caller to have PCP or urgent care asses the site to r/o infection

Painful lymph nodes under left arm and behind left knee; swollen, hard, and itchy area about 4in diameter near injection site.

Went to ER, then admitted to hospital with Mesenteric adenitis?not sure it?s related but wanted to pass on as doctor mentioned it could be as swollen lymph nodes seen in other areas after vaccine. Spent nights in hospital with sharp abdomen discomfort, decreased kidney function, nausea, vomiting.

Swollen supraclavicular lymph node on left side (same side as injection). Started 24 hours after the 2nd dose. Now at 2 weeks it is still swollen and one other lymph node in same region is also swollen. Going to clinic in two days to get checked out.

Redness in the face an neck, slight swelling. Mouth going numb. Both lasting only 30 seconds to a minute. Happened 20 minutes after the shot.

I provided the vaccine to the patient. She was very anxious preceding the vaccine per my observation of her behavior, her own report and her grandmother's comments. She said that she tolerated the first vaccine well except for a "dry throat" that was relieved with sips of liquid. Fourteen minutes after the vaccine her grandmother reported that the patient was distressed. I observed that the patient was conscious, able to talk, and panting. She didn't appear pale or sweaty. I offered to call an ambulance and the patient and grandmother agreed. The patient complained of swelling and difficulty breathing. She did not wheeze or complain of dizziness or nausea. The patient's grandmother refused an EpiPen injection. The ambulance arrived and the patient was taken to the ER.

Initial arm pain that went away after 48 hours that spread up the neck and a headache in the first 24 hours. However, it went away and then yesterday (April 28) I noticed the arm soreness returned. This morning (April 29) the spot was itchy and more sore. This evening it is somewhat swollen and very red, continues to be itchy and aches.

Initially with angioedema lips and eyes. Then hives developed. Went to Urgent Care and was given oral methylprednisolone and antihistamines. Seen in our office today for follow up. Stable. No shortness of breath or wheeze. No chest pain. No abdominal symptoms. Never had allergy in the past. No lip fillers.

I had allergic reaction to where my whole left side was swollen and numb to where I couldn?t feel anything plus when I was eating too.

Exactly one week after the shot, I got a bit of covid arm meaning the injection site was visibly red but there was no swelling or itching. Now, starting yesterday, I am dealing with all-over body hives. Yesterday much of my neck was swollen and bright red. Today my hands are swollen and bright red with hives elsewhere on my body. I?ve been taking Benadryl.

Patient states her arm was swollen, red, hot to the touch and itchy. She stated she had fever along with rash.

Pharmacist advised me to report that I felt my lymph nodes swelling. Bump in my left armpit that happened a day or two after vaccine. Went away after a 1-2 days.

40 mins (3:10 pm) after injection, Hands started feeling like they were on fire, discolored, veins over thumb areas were enlarged and swollen. Swelling went up to forearms. Face was flushed and started to swell. Feet initially swelled and then became numb and cold. Went to ER as I'm anaphylaxis to Benadryl. Was given 125mg of IV steroid and 40 mg of IV pepcide @ 3:45pm. Allergic rxn symptoms subsided within 20 minutes of medication. Was given a 3 day dose take 60 mg of Prednisone.

Patient states that she has swelling and hives and the left side of her body. Referred pt to md or urgent care

Right arm is bigger than left arm.; After 1st vaccine my right arm was little bigger than left arm but after 2nd vaccine it got worst; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of PERIPHERAL SWELLING (Right arm is bigger than left arm.) and CONDITION AGGRAVATED (After 1st vaccine my right arm was little bigger than left arm but after 2nd vaccine it got worst) in a 21-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 032M20A and 024M20A) for COVID-19 vaccination. No relevant medical history was reported. Concomitant products included FLUDROCORTISONE for an unknown indication. On 11-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 11-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient experienced PERIPHERAL SWELLING (Right arm is bigger than left arm.) (seriousness criterion hospitalization) and CONDITION AGGRAVATED (After 1st vaccine my right arm was little bigger than left arm but after 2nd vaccine it got worst) (seriousness criterion hospitalization). The patient was hospitalized on 17-Apr-2021 due to CONDITION AGGRAVATED and PERIPHERAL SWELLING. At the time of the report, PERIPHERAL SWELLING (Right arm is bigger than left arm.) and CONDITION AGGRAVATED (After 1st vaccine my right arm was little bigger than left arm but after 2nd vaccine it got worst) outcome was unknown. The patient also reported taking an unspecified birth control pill concomitantly. The patient reported going to the ER on 17-Apr-2021 due to possible blood clot in right arm. The doctor did not find any blood clot, and the patient was not prescribed anything. The patient received both scheduled doses of mRNA-1273 prior to the events therefore, action taken with the drug in response to the event is not applicable. Based on the current available information and temporal association between the use of the product and the start date of these events, a causal relationship cannot be excluded. This case was linked to US-MODERNATX, INC.-MOD-2021-148205 (E2B Linked Report). Most recent FOLLOW-UP information incorporated above includes: On 19-May-2021: No new information provided.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of these events, a causal relationship cannot be excluded. US-MODERNATX, INC.-MOD-2021-148205:First Dose Case

On 12/20/20 i had received the Moderna covid vaccination. 3 days after i had recieved the vaccination i had felt like i had a stiff neck on the same side of my body that i receive the vaccination on. I had just ignored it until i noticed a "bump" on the side of my neck. I felt it and felt a large swollen lymph node. Again I had decided to ignore the reaction as i figured my antibodies were at work. I had decided to not get the second dose 28 days later as the lymph node had not gone down yet. It is now 06.04.2021 and the lymph node is still there, at this point it is causing an uncomfortable pain in my neck as it is growing. I would like a letter stating i am medically except from receiving the second vaccination in order to fly. Thank You.

patient called this morning around 9:00 am. She states that since getting her covid vaccination yesterday, she feels really sick. Fever/achy and she is having facial swelling. She said she didn't feel like this after the first dose. Since facial swelling is an abnormal and dangerous side effect, I recommended she go to the ER (or at least an urgent care) to be evaluated immediately because she doesnt want the facial swelling to get worse or extend to her breathing. She stated at that time she was having no trouble with her throat or breathing. She said she was going to go to the ER. I told her in the meantime she could take liquid benadryl while on her way to the ER

Patient experienced a 104* fever along with nausea and vomiting following her second Moderna COVID-19 vaccination. She also developed hives all over her body and continues to have random moments of anaphylaxis.

Large painful red welt on injection sight appeared around 10 am the next day. Around 11 pm after recieveing the injection at 4:30 pm I became very fatigued more so than normal. My arm started hurting around 6pm progressively getting more painful and inflammed. Around 2 am i starting having chills and shakes, migrane, as well as body aches and progressively got worse around 11 am the following morning the shakes stopped i woke up with congested sinuses and a migrane as well as enlarged lymph nodes in my underarms and under my chin and jaw. I had extreme fatigue all day following. Currently at 7pm the injection site is red, hot to touch, raised in a circle around the size of a half dollar, it also is very painful to move my arm and very painful to touch.

Right after administration, patients arm started bleeding a lot so we cleaned up the blood and were going to switch out the bandaid and noticed her arm was already really swollen and hard (like a big marble under the skin). She then said that she was feeling really dizzy and thought she was going to pass out. She turned white and said she felt very sick. She leaned back in her chair and a cold ice pack was applied to her forehead and the injection site. This continued for about 30 minutes and then colored returned to her face and lips and she said she was feeling much better.

1st shot SOB, tachycardia,, egg allergy once vaccine made effective. I ate eggs day of shot. 2nd shot made lymph nodes in throat swell to where I couldn't eat solid food. Had barium swallow done and had to have esophagus stretched in EGD.

21 yo pregnant woman, at 28 weeks gestation. EDD: 9/10/21. No complications in pregnancy. Completed series of Moderna covid vaccine. Two days after vaccine she started experiencing new onset chest pain and dizziness. Presented to ED on 6/22/21 and found to have spontaneous coronary aortic dissection (SCAD), with elevated troponin levels (3.180). No evidence of myocarditis. Transferred to hospital, with cardiologist. Currently being treated with blood thinner and beta blocker.

Back pain along spine and headache started during the night (about 12 hours after vaccination). It was bad enough to keep me from sleeping. I started running a fever during the night as well. I got up around 5am because I could sleep with the pain , I took my temp it was about 101. I was also nauseas. This lasted a few hours and was relieved with 600mg ibuprofen. My arm has been painful the entire time (4days now). Redness around the site has been getting larger. It started as just a small circle but after two days it started to grow to about 2?x4? and by today (day4) it covers my entire bicep and is starting to wrap around. It is also mildly itchy and swollen. On the 31st I work up with a painfully swollen axillary lymph node on the left side. It stayed swollen and painful for about a day.

I received the Moderna Vaccine on 12/28/2020. I had no immediate reactions. By 6-7pm that night I started having severe pain in my right arm. The next morning 12/29/2020 I woke up with a migraine and still had severe pain in my arm. That night (12/29/2020) I began feeling aches and pains throughout my body and felt that into the next morning (12/30/2020). The evening of 12/30/2020 I noticed a dollar coin sized red spot on my arm that was warm to the touch and was slightly raised. (By this time my arm pain had decreased but was still present.) The red spot had grown slightly by 12/31/2020 but not much. Friday 01/01/2021 I hadn't payed much attention to the spot but it looked the same. The morning of 01/02/2021 I woke up and had noticed that the spot had taken over a large portion of the outer bicep on my right arm.

Moderna COVID-19 Vaccine EUA Chills, headache , fatigue on night of vaccine only 12/31/20 Tired, headache, muscle pain, lymph node in left armpit swollen/painful 1/1/21 Lymph node pain gone 1/2/21 *Shortness of breath/chest pain 12/31/20 - currently

First day 10 mins after injection my left ear popped then at 10PM I started to feel body aches and had a low grade fever of 99.8 at 10:09PM. At 10:28PM my temperature went up to 101.5. Took Tylenol and fell asleep woke up at 3AM fever of 102.3 . Fell asleep and woke up again with a fever of 102.6. I had chills nausea weakness body aches headache. Took Tylenol again and fell asleep only to wake up again at 6:30Am still with a fever of 102. Nothing was making it go away I had no appetite extremely fatigued and nauseous it felt like I had covid again. I also felt swollen lymph nodes under my arm. By Sunday I was feeling way better and my fever was gone. Monday my ear popped again lasting a minute that?s never happened before. Monday today 01-05 still having headaches and now chest pain. I felt so bad I wanted to go to the hospital but did not it really did feel like I had covid all over again I would not want to put my self through that again. Also I did have covid back in October I believe just wanted to put that out there.

Four days after getting the vaccine I developed a hive-like rash in the form of elevated, itchy, red spots all over my left arm. Took Benadryl but did not do much and woke up the next day worse and with more spots. Went to critical care and was given prednisone which has helped alleviate it but is not completely gone yet (1/5/2021).

Patient received Moderna vaccine on 12/29/2020. Complained of slight soreness the next day and then resolved. Patient reports she noticed sore, red raised area last evening, almost 1 week post injection. Area measures 4cm x 3cm induration. Area is not warm to the touch. Patient denies any other symptoms.

I received the Moderna COVID vaccine on 12/29. I had some minor swelling and soreness the first couple days after receiving the vaccine, but these symptoms both went away after a couple of days. A week later on 1/5, I noticed that the area where I had been injected was very swollen, red and itchy. It was localized to this year. There was some slight bruising around the top of where the swelling started. The area was not sore. There is still some redness and itching on 1/7 but the swelling has mostly gone down. I work in a community health center and had a PA I work with look at the reaction. I took some Benadryl as directed on 1/5 but have not treated the symptoms further.

Lymph node swelled in right armpit on Wednesday night is still swollen. On Saturday 01/09 right arm swelled at injection site and had a hive. Benadryl helped with the swelling/hive at injection site.

Approximately 1 week after getting the shot, the patient experienced a red, swollen, itchy arm. Consulted with her doctor who then prescribed Keflex for Cellulitis

Received vax 12/22; 12/23-12/27 dizziness, light headed, fatigue, swollen left arm, left arm tender/warm to touch/red, muscle of injection site swell to x3 of size; 12/27-12/28 muscle/joint pain (felt unbearable to stand), hips/hands/feet/knees achy, hands swollen and hurt to grasp, red bumps appeared that were itchy, painful and turned into a rash over hands; 12/28 noticed same rash from fingers appearing on toes. 1/4 noticed a had lump in my arm; possibly swollen lymph nodes. Muscular/Joint pain has subsided however I still have the rash and my hands are swollen in the mornings/evenings, spots are painful and still have the lump in my arm. I was prescribed a topical steroid by PCP and has the rash is still there.

I developed a swollen supraclavicular lymph node above my left collarbone. It appeared just a few days after receiving the vaccine. No other side effects were noted aside from a sore arm and some itchiness around the injection site that lasted for 5 days after getting the vaccine. The lymph node is still swollen but is not worsening or painful. My sore arm and the itchiness have improved and are no longer an issue.

Slight swelling in my arm, incredibly tender/sore approximately 3 hours after receiving vaccine. Following morning I noticed I had a fever of approximately 100 degrees. Took ibuprofen at approximately 11pm on the day I received the injection.

Pain in left arm at injection site, swelling and pain of lymph node in left armpit, headache, nausea, fever, body aches

Dates 1/1 - 1/4 experienced arm soreness and pain Dates 1/6-1/11: 1/6 experienced onset of soreness and tenderness around L axillary lymph node. 1/7 lymph node began swelling up. 1/8-1/10 experienced swelling and tenderness of lymph node, fatigue, GI upset including abdominal pain and diarrhea, and general malaise, along with redness and itching where the injection site was the week prior. Every symptom except the swollen lymph node faded after 1/11, and the lymph node has gradually and steadily decreased in size up to today. It is still slightly swollen.

Right after the vaccine was administered, my shoulder was swollen and very painful. I was amenable to move my arm. Those symptoms subsidized after 2 days. A week after the vaccine (1/19/2021), a lump appeared on my shoulder where the injection was done. The area is red, itchy and warm. Those symptoms have been observed for 2 days now.

I was born in another country so I received the BCG vaccine. I have a little scar on my arm from when I got the vaccine. After getting the Covid vaccine, I noticed that my BCG vaccine scar was red, raised, and hard. It looked like a little induration.

first dose of moderna vaccine (1/13 on L arm), admitted 1/24/2021 with progressive fever sore throat and odynophagia found to have RIJ lymphadenitis. Now persistently febrile, hypotensive, tachycardic

One week after vaccination, there was swelling in the armpit of the same arm of injection. The swelling was tender, but went away after about 2 days. About 3-4 days later, a red, tender rash developed in the armpit of the same arm of injection. The rash is dry and burns to the touch. There is also a small patch of rash on the right armpit (not arm of injection). The rash on the left armpit completely covers the area.

I got the vaccine the 28th I was fine until I sat down for dinner I started feeling bad, next day I woke up with a migraine which is not abnormal for me. It went away and I had body aches later that day and the next day. Thursday I had a red spot on my arm below the injection site. The following week my whole upper arm was swollen and I couldn't lift it , I went to the urgent care, they gave me antibiotics 500 mg 4x daily. The meds made me really sick and I quit taking it. and I started feeling better

I received my vaccine while I was at work around 1400. Around midnight I woke up shivering and could not get warm. My heart rate was elevated but that could have been related to my anxiety. I layered clothing on and finally managed to sleep. Upon waking up around 6 the next morning, I had a temperature of 102, a sore throat, throbbing headache, and was vomiting. My arm was so sore and swollen that I could hardly touch it. After rest, Tylenol, and fluids, I felt better around 8 that evening.

Immediate dizziness @ 10:00 AM, thought it was related to anxiety. Left after sitting for 20 minutes because I thought the "anxiety" would resolve best at home. Arrived home at 10:25 AM. My lips started itching, and then swelled along with my tongue. My throat felt tight and I tried to take an oral Benadryl. It got stuck in my throat and I was unable to swallow the pill. It was also difficult to swallow water. I arrived at the ED by 10:40 AM, where I was treated with IV Benadryl and Solu-Medrol. I remained swollen all over, especially in my fingers, for the next 4 days. I gained 12 pounds, either from the reaction or the steroids. My airway did not fully close.

Urticarial and facial angioedema without respiratory symptoms treated the in ED with epi and discharged with recrudescence of her rash and angioedema several hours later and admitted for observation and symptomatic treatment

Inflamed supraclavian lymph node and local site injection inflammation. Stated lymph node became inflammed the day after injection, which subsequently was misinterpreted by a physician as a potential aneurysm (pulsating mass), resulting in unnecessary hopsitalization. With reference to the site injection, left deltoid became red, itchy, and hot initally surrounding local site only. However, as days progressed, reddening spread radially to extend to a final diameter of approxiamtely 5 inches, which also required medical intervention. I was presecribed steroids and anitbiotics which alleviated said symptoms. The symtpoms went away 3 weeks after first dose injection. Physicians advised against taking second dose.

Painful raised red bumps on right side of neck. The bumps do not itch or get better with Benadryl. The pain can be described as burning. Pain gets worse if the bumps are touched

I experienced general symptoms like fever, chills, aches (bad), neck lymph pain, fatigue, and nausea but the fever reached 102 degrees Fahrenheit which is slightly high. A concerning side effect was that my resting HR was consistently above 105BPM from about 4:30AM-4PM the day after receiving the second dose. It reached as high as 125BPM without doing much movement at all to account for the high HR.

Chest tightness starting ~4 hours post-injection accompanied by increased HR and mild pain/pressure on deep inspiration. Occurred intermittently for the rest of the evening (1/25/21) and into the next day (1/26/21). Mostly located along the left side of the sternum and at the base of the sternum. In the following 9 days (to today (2/3/21)) symptoms persisted, occurring about once a day and gradually becoming more mild. On day 4 post-injection (1/29/21) enlarged and tender lymph nodes were noticed in the left axillary region and supraclavicular region. They grew in size and increased in tenderness to mild pain until 2/1/21 and have since been steadily decreasing in size and in tenderness although still noticeable in size and uncomfortable today. Symptoms did not prevent me from doing my normal exercise or school activities. No treatment or medications were taken.

One day after the vaccine, I had a horrible sore throat, body aches, joint pain, lymph node swelling under left axilla and left side of throat. Also runny nose, Fatigue and headaches. This only lasted 1 day. I felt better on day 3, after the vaccine.

presenting today for Sore Throat. Got vaccine on 1/22. Started with sore throat. The started with chills, chest pain, abdominal pain, swollen lymph nodes.

First day of the shot immediately I had a headache and my stomach started to hurt really bad. My arm hurt and swelled up for a few days with a large red bump. After a few days the bump went away. Im still having headaches, ive had diarrhea from day 1. I already struggle with my bowels and go to the bathroom way to much already and after given the vaccine those next days and still days continuing after I cant stay out of the bathroom. In 6 hours i had over 7 to 10 bowel movements and I hadnt ate a thing. As i thought I was getting better I woke uo the next day with my throat swelled up and i was all congested like a cold my body is very tired very sore a very light cough formed as well too my breathing is ok so far, my body on the inside feels like its on fire but im cold on the outside, one minute i was cold them im burning up. Its making me very overwhelmed and my nerves are all over the place.

At 6:30PM on 2/6 (29.5 hours after I received my 2nd Moderna vaccine dose), I developed a small cluster of hives on my left arm around the crease of my elbow (4-5 inches away from the injection site). The hives continued to spread outward until they covered about 25% of my arm 2-3 hours after the hives first appeared. This was the height of the pain/swelling/itchiness. The hives gradually moved upward along my arm and are currently an inch or two below my injection site (5 hours after the adverse effects began).

I had a hive outbreak on the back of my thighs, on my elbows, on my arms. Sometimes my hands and feet would swell up.

Systemic: Allergic: Anaphylaxis-Medium, Systemic: Allergic: Difficulty Swallowing, Throat Tightness-Medium, Systemic: Allergic: Swelling of Face / Eyes / Mouth / Tongue-Medium, Systemic: Dizziness / Lightheadness-Mild, Systemic: Fever-Mild, Systemic: Flushed / Sweating-Mild, Systemic: Tachycardia-Mild, Additional Details: Had to use 1 epi pen in left upper thigh

Started getting sore again a week after I got the shot. Then Got an itchy arm 2/14 at night around 10pm, but didn?t think anything of it. Woke up in the middle of the night and realized there was a lump right above my collar bone. Then saw the faint rash in the morning and a little bit swollen. Itchiness is nothing too bad. Soreness started to go away, but lump still there.

My face began swelling around my chin, mouth, & cheeks around five hours after receiving vaccine. I also felt flushed & appeared red. My voice became raspy. Mild GI pain/discomfort.

Anaphylactic reaction; Burning sensation in eyeballs; Wheezing; Rales; Airways were closing; Can't breathe; A spontaneous report was received from a consumer concerning a 22-year-old, female patient, who received Moderna's COVID-19 vaccine (mRNA-1273) and experienced an anaphylactic reaction, burning sensation in eyeballs/abnormal sensation in eye, wheezing, rales, airways were closing/obstructive airways disorder, and can't breathe/dyspnoea. The patient's medical history was not provided. No relevant concomitant medications were reported. On 05 Feb 2021, within 5 minutes prior to the onset of the event, the patient received their second of two planned doses of mRNA-1273 (Lot number: 011J20A) intramuscularly in the left arm for prophylaxis of COVID-19 infection. On 05 Feb 2021, within 5 minutes after receiving her second dose of vaccine, the patient reported a burning sensation in her eyeballs, followed by wheezing and rales in her lungs. She was given epinephrine and taken to the emergency room via an ambulance. She was given a second dose of epinephrine. Her airways were closing and she could not breathe. She was given a steroid, diphenhydramine, H2 antagonist and albuterol. Consent given for follow up calls. Action taken with mRNA-1273 in response to the event was not reported. The outcome of the events, anaphylactic reaction, burning sensation in eyeballs, wheezing, rales, airways were closing, and can't breathe, was not provided.; Reporter's Comments: Based on the current available information and temporal association between the use of the product and the onset date of the events, a causal relationship cannot be excluded.

What appeared to be a welt over injection site. It was itchy, red, raised slightly, warm, and hive like. They are calling it ?covid arm? when researched. It appeared one week after the shot was administered and stayed for four days. I did not take any medicine besides Tylenol. I also had a swollen lymph node in the same armpit for a couple of days.

Red lump showed up on left arm the morning after vaccination. Arm remained sore and swollen for 5 days, after this the lump went away. On 2/18/21 left arm started itching where vaccine was given, and the morning of 2/19/21 red lump and soreness returned.

Vaccination 1: (symptoms onset ~4-6hrs after injection) >>>following morning: severe pain throughout entire body, swelling in hands/feet, chills, tiredness, brain fog, nausea, cold sweats, and fever. Vaccination 2: Allergic reaction about 30+ mins after vaccination after heading back to the car. Cold, clammy, pale, disoriented, hives across skin, dry mouth, and itchiness >>>Next morning: severe pain throughout entire body, swelling in hands/feet, chills, tiredness, brain fog, nausea, cold sweats, and fever.

I noticed Left underarm tenderness as I woke up on 1/25/21. Upon further examination, I discovered that what I believe to be my left lymph node is noticeably swollen and tender to the touch. No treatment has been initiated at this time.

Severe anaphylaxis allergic reaction; Passed out on the ground; A spontaneous report was received from a consumer concerning a 22-year-old female patient who received Moderna's COVID-19 vaccine (mRNA-1273) and passed out on the ground and had a severe anaphylaxis allergic reaction. The patient's medical history was not provided. Concomitant product use was not provided by the reporter. On an unknown date, prior to the onset of the events, the patient received their second of two planned doses of mRNA-1273 intramuscularly for prophylaxis of COVID-19 infection. About 10 minutes after receiving the second dose of the Moderna vaccine, the patient passed out on the ground having a severe anaphylaxis allergic reaction. Treatment for the event included two doses of epinephrine IM in addition to diphenhydramine, ondansetron, and steroids to prevent a rebound reaction. 911 was called and after epinephrine and diphenhydramine were administered, the patient was immediately transported to the hospital where she stayed for 6 more hours for observation, fluids, and further medications. Action taken with mRNA-1273 in response to the events was not applicable. The events, passed out on the ground and severe anaphylaxis allergic reaction, were considered resolved; Reporter's Comments: Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded. Anaphylactic reaction is a listed event in CCDS.

1 hour after shot. Numbness in face, tingling in face; tiredness and fatigue , headache, hand tingling, gradually swelling of the throat, neck tenderness and swelling, trouble swallowing and. breathing, chills and fever, itchiness ; dizziness

Lymphadenopathy- left anterior cervical chain, left supraclavicular, left postauricular, left axillary. no other symptoms

3/5/21, 3/6/21 and still is exhibiting side effects - Fire and burning sensation all throughout my body, shooting pains down my left arm of where I got the vaccine, body chills, low-grade fever, nausea, vomiting, diarrhea, and dizziness, confusion, lightheadedness, and blacked out. Fell and hit my head and got a concussion.

Itchy, red, hard bump on arm about 7 days after my first dose. I know it is normal and known but wanted it documented for stats and my account also. In terms of treatment I?m just using lotion and ice to keep the swelling down. It is not affecting anything else other than more fatigue in the last week.

A week after I received first shot arm swelled, became itchy, hot to touch, and began to hurt a bit again.

pruritic erythematous rash on neck 30 minutes after injection, then blotchy erythematous pruritic rash and swelling of face and eyelids 5 days later

Fever about 100.5 lasting about 26 hours resulting in chills, sweat, and muscle aches. Fatigue lasting about 2 days. Headache lasting 48 hours. Nausea lasted about 5 hours about 18 hours after injection. Pain in left arm where injection was starting about 5 hours after injection and has not gone away yet after 52 hours. Swollen and very painful lymph nodes in arm pit on left side (injection side) starting 36 hours after injection and has not gone away.

Swollen, red, tender, hard, and giving off heat at site of injection. Lymph nodes on same arm are swollen as well. Headache, fatigue, dizziness, random spurts of sweating, and not wanting to eat anything. All started day after vaccine. I have taken Benadryl that helped significantly started taking on Friday(3/12/21). Lymph nodes are still swelling and injection area is starting to itch.

Horrid body aches and chills Trembling Very high fevers Hard spot and rash where vaccine was given Trouble regulating body temp Migraine nonstop Swollen lymph nodes in neck region Stiffness Swelling to fingers with occasional lack of blood flow (turn blue)

Red spots on upper arms on 12/31/2020 at injection site. it was dry, itchy and hot to touch and lump in my left armpit. By the next day it had swollen and was welted. That evening went to ER and was diagnosed with cellulites treated with Keflex. on 1/3 went back to ER as it was not getting better. Diagnosed again with cellulites and give sulfa,

Local soreness to left arm approximately 1 hour after injection. Swollen lymph nodes in left armpit after 2 hours. Night sweats. Both arm soreness and lymph node soreness persisted 18 hours later.

The patient received the vaccine at approximately 8 p.m. on March 16, 2021. She waited the 15 minutes and more in the waiting area with no adverse event taking place at the pharmacy. Later on overnight the patient experienced face swelling that continuously progressed for 48 hours. The swelling eventually subsided, but the patient has concerns about receiving the second dose and wants to know should she proceed with the follow up dose.

I had a swollen lymph node next to my left armpit under my collar bone. It was sore and semi-hard. I explained it to my doctor that if felt as if there was a marble under my skin. After about two weeks the soreness went away and after three weeks (and the second dose) there was no sign of the swelling.

allergy: nuts, dairy - anaphylaxis Hx: asthma Not pregnant Patient was found sitting on ground with swollen face, lips, and hives on bilateral arms, back, chest and abdomen. Patient is aox4. Patient already took 50mg PO Benadryl and used her albuterol. Partner at side. Patient stated she had a sandwich about an hour and a half before that might've cause allergic reaction. Patient does carry an epi pen, but not today. 1230 bp 100/60 hr 97 o2sat 99%. 50mg IM benadryl administered to left arm at 1230. 1240 hr 120, o2 sat 99%> No relief and now patient is coughing, 0.5 mg epi im to left arm. Laid patient down. Ems called. Patient remains conscious and alert. Noted she was feeling better before EMS arrived.

A few days after I notice my lymph nodes in the left side of my neck swole which is still swollen to date but doesnt hurt as bad and my arm at the injection site hurt really bad for a few days but subsided

Early the next morning after the vaccine the scar from a previous turbulosis vaccine I took while a child turned really red, got warm and developed a big hard bump on it but it went away after about about 5 days. It was really really red and the redness was about 10 inches in size

Systemic: Allergic: Anaphylaxis-Medium, Systemic: Allergic: Difficulty Breathing-Medium, Systemic: Allergic: Difficulty Swallowing, Throat Tightness-Medium, Systemic: Allergic: Itch (specify: facial area, extremeties)-Medium

About a week after the vaccine my arm begin to itch super bad. Which presisted to getting hot, red, hard and swollen which made my arm super sore and very painful. Over the next few days it grew to about 6" in in length and a raised bump of about 1cm appeared. I took benedryl and used hydrocortisone cream and ice packs to help and after about 5 days it finally dimished.

within seconds of vaccine administered patient began vigorously itching, visually seeing red hives, swelling around neck area coughing, chest pain, SOB. Within 3 minutes epinephrine was administered and patient was put on oxygen. Medic called for transport and patient became irritated and angry refusing all treatment and ripping off oxygen, pulse ox, BP cuff, ect? At approximately 1409 patient was doing better, hives still visible but walked out of facility.

1/15 vaccination 1/22 At 3am, I woke up and my R arm burned and itched so bad. I went to brush teeth and saw arm; swollen R arm, tender to touch, and tingle if raised. I called my PCM. Set up a telehealth appt. She looked at it and stated to take a antihistamine. By Sat morning, it was gone.

Patient was sitting in observation area 5 minutes post vaccination, scheduled to be observed for 30 minutes total due to history of anaphylaxis. She was seated in the recliner She reported to have itchy watery eyes, chest tightness. Breath sounds were clear, with good air movement bilaterally, no wheezing or crackles, no accessory muscle use, normal speech. Patient's boyfriend noted her tongue and eyelids to appear slightly swollen compared to baseline. Patient denied dizziness, chest pain, shortness of breath, body rash or itching. Patient maintained normal speech and normal unlabored respirations. BP was checked and noted to be normal. O2 sat 99%. Patient received benadryl 50mg PO. She was observed for about 10 minutes before her tongue appeared more swollen and she complained of difficulty breathing. At this point, the patient appeared pale, 911 was activated. EPI-pen was administered via autoinjector in the left lateral thigh. O2 sat was 99%. Patient has increased chest tightness and new onset shortness of breath for which she was given an Albuterol nebulizer. Breath sounds were clear, no wheezing. O2 sat reassessed which decreased to 73%, she had bilateral cramping of hands and digits. Non-rebreather was applied, oxygen saturation improved and hand cramps resolved. 911 was called for a second time to report rapid desaturation. Patient's O2 saturation and HR fluctuated, BP remained stable throughout. EMS arrived. A right AC IV was placed, Solumedrol 125mg IVP was administered by EMS. Patient was transferred onto EMS stretcher, still requiring nonrebreather. Patient was escorted to ED for further management of anaphylxis post Moderna vaccine.

Moderna COVID-19 Vaccine EUA I had swollen lymph nodes in my arm for the week after my vaccination. A week after my first dose (4/9/21) I started getting a rash at the injection site. It travelled around my arm from the spot where the needle injected me, towards the inside of my arm and down toward my elbow. I have been taking a typical antihistamine from drug store and applying hydrocortisone to the area. It provides a little relief but my arm is still swollen, hot, and itchy.

Left upper arm Adema and erythema overlying the deltoid area tender to the touch with small vesicles. Local topical hydrocortisone 2 1/2% and cold compresses advised along with protection of the area and pain medication

Pt returned to clinic on 4/13/21 with report of allergic reaction to vaccine received on 3/15/21. Pt states approx 6-8 hours post vaccine she had sudden onset shortness of breath, chest pain, throat discomfort, skin rash, itchiness, facial and hand swelling. She sought medical attention Emergency Department where she was treated with PO steroids, Benadryl and anti-hypertensives. Symptoms resolved same day and she was subsequently discharged home. Pt followed up with PCP who advised her not to receive the second dose

PT was complaining of numbness and tingling on Rt arm of vaccination site. fingers became swollen on RT side

I had a sore arm for two days after I received my shot. And just recently on 04/12 I started to experience a pain under my skin in my underarm area, I assume a swollen lymph node.

After receiving the shot I was fine for the first few hours. Then my arm started to get really stiff and felt almost swollen. I had my mom check it and it wasn?t swollen but the day after I woke up and felt like something wasn?t quite right. I felt where my lymph nodes are near my clavicle and there were very swollen almost the size of a golf ball, my lymph node under my armpit was also quite swollen. I had a headache on the left side of my head and around my eye. My lymph node near my clavicle is still quite swollen but I?m feeling alittle better. I kept using a cold compress on my arm and lymph nodes as well as taking Tylenol. I did also have a slight fever of about 100 one night but it went away by the next day.

Axillary lymphadenopathy lasting at least through 4/22/21. Initially LAD was painful, but this has resolved.

Patient received her vaccine at 2:13P and was recommended to wait 30 minutes in the observation area. After waiting 30 minutes patient went to the bathroom and then returned at 2:45P and reported mild throat tightness. RN responded. Vitals taken at 2:49P and 2:58P were within normal limits. Patient reports having previous anaphylaxis reactions to mushroom and bee stings. Also, reports mild allergies to peanuts and eggs. Patient reports no history of cardiac issues. Patient has history of asthma and pre-diabetes. Patient reported itching around the injection site but did not have hives present on either arms, chest, or neck upon inspection. Patient reported that she had not had anything to eat today and drank one cup of juice earlier in the morning. Patient reports that the feeling felt similar to her previous mild reactions to peanuts. Recommended that patient wait to be monitored and be seen by a provider due to previous history. Patient was seen by Dr. 50 mg of Benadryl given PO at 3:09P. Patient expressed she would like to stay in observation "a little longer" for further monitoring. At 3:35P patient reported that the swelling had gotten better and was ready to leave. Patient had her personal epi-pen in her purse and verbalized when it was appropriate to use it. ER precautions also given and patient verbalized understanding. Patient left to take bus home at 3:36P.

Rash about 4 inches long by 2 inches wide and swollen lymph nodes in the axillary region. I have taken already medications to try and help improve it.

Following the first dose, I was referred for an EKG by my primary physician. My heartbeat was irregular and the doctors said it was probably from the vaccination. I had severe arm pain and flu-like symptoms. Dose 2, I had intense lymph node swelling and pain of vaccination site, a three-day continuous fever between 99 and 102 degrees, no sleep and horrible body/head pain.

14 hours after my second dose I became nauseous and threw up yellow bile intermittently (about 5 separate times, each retching fit lasting 5 minutes) until 12:30pm. My primary care physician prescribed Zofran helped curb the vomiting. I also had a fever of 103.1 for half an hour before it subsided to 100, body aches, sweating, chills, headache, and nausea. Today, 4/28 over 24 hours after my vaccine, I started presenting a swelling on my right hand that is itchy and discolored, although the side effects from the day before have lessened to a certain degree.

Two days after receiving the IM injection in her left arm, patient developed soreness at the injection site and painful left axillary lymphadenopathy. It was painful to lift her arm, and she felt a "pulling" on her chest. She was very distressed and sought evaluation by her PCP on 4/29/2021 who told her that she had lots of swollen lymph nodes. She was unable to work for four days because of the pain. The soreness in her arm has resolved, but the swelling and discomfort on moving her left arm persist, although they are improved. She did NOT have any fevers, chills or night sweats associated with the event.

After about 10 hours after the vaccine was administered, I got a fever of 102, which then made its way up to 104.7. I knew the fever was a possible side effect, but it got very bad very quickly. I had to call off of work because I could not stay awake and was in so much pain. My fever has lowered 2 days after vaccination, but has not fully gone down. Also, my neck on the side that my vaccine was administered (the left arm) is very swollen and very painful. I cannot lift my arm and there is a noticeable difference between my left and my right neck in regards to swelling.

There was a delayed reaction starting 7 days after first dose. Symptoms included redness and soreness at the site of injection and swollen lymph nodes in the armpit of the arm where the shot was injected. 12 hours after receiving the second dose I was shaking, nauseated, dizzy, sweating one minute and freezing the next, pain all over the body, my breathing slowed down and lastly there was a loud deafening ringing in my ears. These symptoms lasted a frightening 10 or so minutes leaving behind the bodily aches.

Hot/Cold flashes, fever, stomach pain when urinating, nausea, swelling at the injection site, bruising at the injection site, body aches, head/neck aches, muscle pain in upper chest, headache, migraine, extreme fatigue, excessive sweating, swollen lymph nodes, dizziness

Rash on both arms started about an hour after the vaccine, lightheadedness & dizzy, vision was a little blurry, noticed half of right side of the face was swollen around 7 pm same day of vaccination.

Patient obtained her 1st dose of the Moderna vaccine on May 22nd subsequent development erythema roughly 4 fingers below the injection site, roughly 24 hours after the injection. Notes associated swelling, warmth and discomfort. Denies any open wound, fevers, chills or malaise. Since then, erythema and swelling have progressed by increasing roughly 1 cm in diameter. Notes pruritus and discomfort have improved by the time of today's (5/27/21) clinic visit. She has tried no medications or topicals to treat the rash. No additional sites of rash. She denies syncope, lightheadedness, dizziness, lip swelling, tongue swelling, shortness of breath, wheezing, abdominal pain, nausea, vomiting. No PEG allergy history. No documented vaccine allergies. No allergies causing anaphylaxis.

One week after my vaccine I felt a lump under my left underarm. I observed for a week and it gradually got bigger. I went to my physician and I had an ultrasound done and it showed I had a swollen lymph node. Three days after that ultrasound I went to the ER with severe abdominal pain and was told I had apendicitis. I then had an appendectomy.

Systemic: Allergic: Anaphylaxis-Medium, Systemic: Allergic: Itch (specify: facial area, extremeties)-Mild, Systemic: Allergic: Rash (specify: facial area, extremeties)-Mild, Systemic: Confusion-Medium, Systemic: Dizziness / Lightheadness-Medium, Additional Details: Patient noticed redness and itching on chest approximately 20 minutes after injection but no other reported symptoms. Patient had already had a hive like rash on arm prior to injection. Patient was advised to stay in store for further observation. After an hour of observation patient denied any further new symptoms and departed. She was advised to stay near town and to call 911 if she developed any other symptoms. Patient called 911 approximately 2 hours after departure and was taken to ER.

Anaphylactic Shock about 1 hour post vaccination; Hives all over the body; Swollen Throat; Itching all over the body; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of ANAPHYLACTIC SHOCK (Anaphylactic Shock about 1 hour post vaccination) in a 22-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 049B214) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. No Medical History information was reported. On 04-Jun-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 04-Jun-2021, the patient experienced URTICARIA (Hives all over the body), PHARYNGEAL SWELLING (Swollen Throat) and PRURITUS (Itching all over the body). On 04-Jun-2021 at 1:00 PM, after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced ANAPHYLACTIC SHOCK (Anaphylactic Shock about 1 hour post vaccination) (seriousness criteria hospitalization and medically significant). The patient was treated with EPINEPHRINE (EPIPEN) on 04-Jun-2021 for Anaphylactic shock, at a dose of 2 dosage form and DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) on 04-Jun-2021 for Hives, at a dose of 25 milligram every six hours. At the time of the report, ANAPHYLACTIC SHOCK (Anaphylactic Shock about 1 hour post vaccination) and PHARYNGEAL SWELLING (Swollen Throat) outcome was unknown and URTICARIA (Hives all over the body) and PRURITUS (Itching all over the body) had not resolved. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. Concomitant product use was not provided by the reporter. It was reported that as of 07 JUN 2021, the patient still had hives and itchiness. Company comment: Based on the current available information and temporal association between the use of the product and the start date of these events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of these events, a causal relationship cannot be excluded.

pt received 1st dose of moderna covid-19 vaccine on 06/04/21 and presented to pharmacy on 06/16/21 with complaints of soreness and swollen arm. Pt stated that the symptoms started on 06/11/21. Per pt, she was seen by her doctor yesterday and he recommended a "heat patch" for the pain- which the pt had applied over injection site and refused to remove patch for observation of injection site. Pt also stated that the doctor already prescribed muscle relaxant medication and that she only presented to the pharmacy to report the adverse effect.

22F healthy female received Moderna vaccine doses on 2/4 and 3/4. Reports fever/chills, HA, sore throat on 4/7. Had abdominal pain, diarrhea and vomiting on 4/21. She went to the ED on 5/30 for bilateral hand swelling and joint pain. Also saw Ortho on 6/3. Labs notable for: elevated CRP, mildly elevated TSH with normal free T4, proteinuria, ANA 1:1280, lyme panel IgM equivocal with negative IgG. Kidney biopsy showed lupus. Seeing Nephrology, Rheumatology. Started on atovaquone, prednisone, mycophenolate, and hydroxychloroquine.

she received her 2nd Moderna vaccine 5/5/21 at a pharmacy. she presented to my clinic on 5/7/21 with complaints of left sided upper body swelling/itching (including her face, which had improved by time of presentation) and left arm soreness. she had visible erythema, swelling, and tenderness of upper left arm but no other physical exam abnormalities at the time of my evaluation on 5/7/21.

Patient says that she experience swelling under her armpits after receiving her first dose of the moderna vaccine.

My lymph nodes swelled up, but I do not remember when it started but it has been like this for a few months since April. I decided to go to the doctor on June and I had to wait to get in. He did a manual examination and prescribed me an antibiotic called Azithromycin for 5 days to see if my lymph nodes will swelled down but they did not.

10am, shot was administered. 9pm pain in my arm started. 10pm pain became worse and arm began to swell. 11pm body aches began and fever of 100.6, 12am chills began, 1am, headache (mild). Throughout the night I had fevers ranging between 101 and 102.4 I sat at 101.7 for a few hours (without the use of Tylenol). Got up for work by 9am. Did not sleep at all through the night. Body hurt a lot, fever of 100.7, arm is hard, hot, and red. Spot around injection site is growing. Took too Tylenol around 10am to make it possible for me to work. Chills became mild and temp dropped to 99.6 for most of the time I was taking Tylenol. 24 hours after the symptoms started they went from severe to moderate (without the use of Tylenol). Was able to sleep last night. No chills but still had a low fever 100.6 woke up today and my body hurts. Temp was 99.3 at 10am. By 4pm 2 days after getting the vaccine my are is still very hot to the touch, red, and hard. It does not look better. Back to normal temp 96.6 and body hurts in the mild range.

Acute appendicitis, onset morning of 1/1/2021 (Reporting this because Pfizer covid vaccine had 3-4x higher risk of appendicitis, although data not reported for Moderna covid vaccine)

After about 2-3 minutes from vaccination, the patient's hands bilaterally became swollen with erythema. It was clearly visible. The patient also noted "tingling" in her right arm where she received the vaccine. In addition, there was localized erythema at the injection site with about 5 cm in diameter. I gave the patient 37 mg of Benadryl and the edema immediately was reduced in addition to the erythema resolved. She had no more tingling. I observed her for 30 minutes and all was fine with the patient. I then checked on her 1 hour later and all was good.

Redness and pain of the arm., Shortness of breath, relieved with albuterol nebulizer at home. Sensation of swelling in the throat, but normal examination. Lungs were clear auscultation. Pulse oximetry was normal. Patient was prescribed an EpiPen, and instructed to go to the emergency room for any worsening of symptoms. Steroids were not prescribed.

COVID VACCINE: I began with a discomfort in my axillary area. Then it got worse and has caused swelling on my axillary area and upper left chest area. I have lost ROM on my left arm and seen a provider to get anti-inflammatory medication.

Dose 1 administered on 12/28/2020 Fatigue and body aches on 12/29/2020 morning, resolved by afternoon Tender left axillary lymphadenopathy 01/03/2021-present Swelling, warmth, itchiness, soreness at injection site on 01/04/2021-01/06/2021

23 hours after vaccine, had facial and neck swelling and tongue swelling. Had difficulty swallowing. Took Benadryl 50 mg. Happened again after 2 hours (25 hours after vaccine), took another Benadryl 50 mg. Then happened one more time about 36 hours after vaccine, had to use epipen, took Benadryl and Claritin as well. Symptoms improved and throat opened.

On day 1 (day I was vaccinated) I experienced severe pain in my arm where I was injected with the vaccine 3 hours after receiving it. I couldn't use my arm for the rest of the day and had to take Tylenol to help with swelling and pain. Pain was dull and throbbing. The next morning I woke up to body chills, a low grade fever, muscle aches, vomiting, exhaustion/fatigue, coughing, and diarrhea. The injection site was still very tender, sore, and swollen with limited mobility. All symptoms subsided within two days other than fatigue and a sore arm. On day 3 I developed a cough that lasted 4-5 days. Other than a cough, I had no other symptoms after that. My arm was better with no pain and easy to use. Then on day 8 my arm started to swell again and I developed a distinct rash at the injection site. The skin around the area was hot to touch and very hard and tender. I took ibuprofen and rubbed out the arm to help. I contacted my provider and she examined the arm, concerned I was having a reaction and possibly developing cellulitis. On day 9 the rash spread to the whole upper arm and shoulder were hot to touch/feverish, painful, hard, and still swollen. The swelling has continued to move up my arm. I am seeking medical attention today on 1/7/21 for treatment of possible cellulitis.

Fast Heart rate after an hour and half of injection and shortness of breath . Next morning i woke up sweating and my heart rate was 130 and shortness of breath followed. I then developed a rash the same day which was red and bumpy i also felt really lethargic and fatigued. Day three the rash had a line straight through the middle of it and was itchy the rash was spreading horizontally. After day three I felt better with the only side effect being shortness of breath from time to time. Now on the 7th of Jan I develop the rash again except its raised, the line is back and it itches internally. I don't feel bad , it's just concerning that it came back stronger all the sudden. I don't know if I will be allowed to get the second dose.

Moderna COVID-19 Vaccine EUA The day of the vaccine, I was fine besides my arm hurting- the one I got the shot in. That night I went to sleep at 830PM. I woke up a little before 1030PM shaking with chills and nauseated. I couldn't sleep the whole night, going between sweating and shaking. The next day 1/6/21 I was still unwell, didn't go into work, felt weak and sore the whole day and noticed my underarm of the arm I received the shot was swollen and painful,. Today 1/7/21, my underarm is still painful and swollen, but the nausea has subsided. Still slightly going between sweating and being chilled.

Day 8 developed lymph node soreness & swelling in arm of injection, and swelling & redness around injection site. Still slightly swollen today. Patient did have a visit with primary care physician due to worry about lymph node swelling

I received my first dose of the Moderna vaccine on Tuesday, January 5th at 9:00 AM. I felt fine immediately following the vaccine but quickly felt worse throughout the day. I developed a fever of 101.4F with medicine, chills, muscle aches, fatigue, and general malaise. I know these are all common symptoms, so I didn't worry too much. However, my fever has persisted. I stayed home from work Wednesday, Thursday, and Friday due to not feeling well and still having a fever. Thursday, I also developed pain in my armpit with movement and palpation. I am guessing that pain in related to swollen lymph nodes. Friday, the pain in my armpit seemed to spread into my arm. Most of my armpit and the upper inside of my bicep is extremely tender to movement and touch. Today, I still have some tenderness in my arm and my fever is still present. Throughout this week, my fever has remained around 100F, even with Tylenol and ibuprofen. I contacted my PCP yesterday about my concern for my persistent fever and arm pain. They believe that because I tested positive for COVID-19 in October 2020, that I am reacting to the first dose of the vaccine as if I am receiving the second dose of the vaccine. They advised me to continue taking ibuprofen and Tylenol. I am worried that if I receive the second dose of the vaccine, I will be sick for longer.

Headache (began day 1 - consistent through day 4 today), lightheadedness (day 1 - first reaction symptom), nausea (day 1 briefly), total body aches (evening of day 1 severe - through day 4 today but only mild), chills (evening of day 1), subjective fever (evening of day 1), swelling of injection site (noticed the next morning and worsened until day 4 today, started to decrease but still present), rash of injection site (noticed morning after and continued to increase until day 4 today it is less bright red but still present and baseball sized), swollen right axillary lymph nodes (day 3-4), today day 4 injection site began itching. I am continuing to monitor signs and symptoms.

My arm began to feel swollen and when I looked at my arm it had a large area of redness that extended about 4 inches from the injection site. My arm was warm, swollen, and itched.

1/10/21 - Feeling of "pulling a muscle" in armpit in left upper extremity that limited movement. (around 8:00 am). New onset of hives, erythema, warmth, edema, pain, and itching experienced at injection site in left upper extremity (6:34 pm). Call was placed to NP, the provider on call at 6:46 pm. Under advisement of provider, application of hydrocortisone cream at injection site and X2 PO 25 mg benadryl self-administered (around 7:00 pm). Sensation of throat closing and hoarseness/change in voice surfaced (around 7:45 pm). Presented to ED, with complaints as listed (around 8:15 pm). Condition/symptoms treated at ED with 60 mg prednisone and pepcid (8:31 pm) followed by direct observation until 10:08 pm. Prescription for prednisone 20 mg X3/day for 5 days written by MD. 1/11/21 - Arm continued to appear slightly swollen with erythema and warmth at the site. Treatment included observation throughout the day. 1/12/21 - Follow-up appointment attended with provider at 2:10 pm. Told by provider that prednisone would only be necessary in the case of resurfacing symptoms of a hypersensitivity reaction. At this time the cause of said symptoms is undetermined. Tingling sensation experienced in face and direct observation of left-sided facial swelling noticed (5:59 pm). Call placed to provider on call (6:08 pm) . Provider advised to take X2 25 mg benadryl and to take X3 20 mg prednisone stat. Benadryl taken at 6:15 pm and prednisone taken at 6:30 pm. Tingling sensation minimized by 7:30 pm, but left sided facial swelling remains as of 7:40 pm. Plans to follow-up with PCP later in the week and potential for re-visiting ED if symptoms worsen or continue throughout the night.

On the day of (1/5/2021) and day after injection, I experienced pain and a large bump on my arm which I was told is normal On 1/12/2021 at around 6:30pm I noticed that the bump had come back but it was larger than before, hard and itchy. I applied ice to take away the itching and then later applied a Benadryl Creame. 1/13/2021- Today, the bump has spread

Face swelled up, difficulty breathing, fever. Went to ER got Benadryl. Symptoms got worse as time went on about 2hrs after the shot. Congested

Initial vitals: BP: 146/91, HR 115, 100% O2, RR 16 Benadryl 25 mg po given at 9:50am EMS notified and first injection 3mg Epi pen injection given at 9:51am; swelling decreased briefly, then after 5-7' swelling got worse. 911 called. BP 139/97, 128, RR 16, O2 sat 100% 9:50am. Second epinephrine 3mg injection given at 10:03am. Swelling decreased, but periorbital swelling and somnolence, and flaccidity persisted. BP 135/88, HR 116, RR 16, O2 sat 100% at 10:05am. Ambulance arrived at 10:05 and she was brought to hospital.

Fatigue, headache, diarrhea, arm soreness, swollen glands, ear infection, sore throat, muscle aches-- started two days after and is still occurring on day five

Horrible body aches, fever, arm pain and swelling. Fatigue where I cannot get out of bed. I cannot sleep due to body aches. I have a high pain threshold and this is unbearable. I had Covid back in July 2020 and this is just as bad now as it was then.

Swelling, itchiness, pain at the injection site beginning on day 7. Hot to the touch. Red. Progressive expanding of red, hot area. "went from semicircle lump to big half dome". Axillary lymphadenopathy on affected (L) side. Chills at night 01.19 into 01.20. Seeking medical care with PCP on 01.20.

Anaphylactic reaction; A spontaneous report was received from a 23-year-old, female consumer who was also a patient who received Moderna's COVID-19 vaccine (mRNA-1273) and experienced anaphylactic reaction. The patient's medical history included allergy to amoxicillin. Concomitant medications reported included gabapentin, escitalopram oxalate, and montelukast sodium. On 04 Jan 2021, prior to the onset of the event, the patient received their first of two planned doses of mRNA-1273 (Lot number: 011L20A) intramuscularly for prophylaxis of COVID-19 infection. On 05 Jan 2021, within 24 hours of vaccination, the patient experienced anaphylactic reaction. Treatment for the event included Diphenhydramine. Action taken with mRNA-1273 in response to the event was not provided. The outcome of the event, anaphylactic reaction, was considered resolved on 06 Jan 2021.; Reporter's Comments: This case concerns a 23 year old female patient, who experienced a serious unexpected event of Anaphylactic reaction. Event occurred apparently within 24 hrs. after first dose of mRNA-1273 (Lot# 011L20A) vaccine administration. Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.

Anaphylactic reaction: tongue/throat numbness, throat closure, rapid heart rate, dizziness, body tremors.

Patient only had muffin and coffee that day early in am. Had some arm pain after shot no other reaction. Did go home felt some nausea . Did not throw up. Did not eat anything rest of day until around 11:30 pm . Felt much more nauseated and stomach cramping. Said she felt light headed and then had what appears to be vasovagal with brief passing out and then revived and with sweats. Was not confused . Did not loose continence. Was completely coherent after event. Went to ER to be checked out. In ER was found to have UTI and given some Rochephin . Had severe face and body swelling reaction requiring benadryl. Was observed and sent home after several hours. It was assumed that ER had reported this although it was felt by ER and us that this was vasovagal from not eating and nausea and UTI on top of that. Did not feel was secondary to vaccine . ER did not feel it was either. However while probably unrelated we felt should document it.

1/15, all day: very sore shoulder, brain fog, headache. Resolved by next day. 1/20 -1/23 all day: itchy skin around injection site on L shoulder. 1/18-present: lymph nodes in L axilla sore/swollen-- >Resolved in 1 day. Also I got a mysterious, firm lump under the skin on the anterior surface of my L shoulder (still there). 1/24 - present, all day: Visible, oval-shaped rash around injection site. Rash is 3 inches tall, 2 inches wide. Shoulder has vague soreness. Fingers on L hand have sensation of decreased bloodflow.

The day of the vaccine about 4 hours later, I started experiencing chest pain. It was not tightness or a heartburn feeling type of chest pain. I have asthma, and it is the type of chest pain I start feeling right before I get bronchitis, almost like breathing in mist and the irritation that comes from having a cough, but I had not had a cough that would have caused this sensation. The next day, I was extremely fatigued, had a headache, chills, started getting a cough, and was sent home early from work. The day after, Friday, I had a fever of 102 and was essentially bedridden. I started using my nebulizer and my dr called me in some prednisone. These symptoms continued through the weekend and began lifting that Sunday. However, on Monday, my lymph node under my ear started swelling on my left side (the same side as the shot), my ear became clogged, my sinuses on my left side had shooting pain every time I inhaled, and although I could breathe through my nostrils, they felt full and had immense pressure. Additionally my headache became worse and I began experiencing intense muscle pain right at the base of my skull on the left side near my occipital lymph node that was radiating into my head and making the headache and sinus pain worse. Now, 11 days after my first dose of the vaccine, I still have the ear pain, swollen lymph node under my ear/behind my jaw, sinus pain, muscle pain at the base of my skull, a headache, and extreme pressure in my head/sinus area that has not lifted. I started on an antibiotic Friday night (the 22nd) in hopes that this is a sinus and ear infection. Ibuprofen helps the headache slightly but makes the pressure in my head feel worse and makes the joints in my hands and forearms hurt and my fingers swell for some reason which has never happened before for me when taking ibuprofen.

Very sore armpit/swollen lymphnodes. Raised bumps and redness and itchiness all around injection site. All started on 1/24, 6 days after receiving dose 1.

Fatigue (2 hours after injection, lasting until following Monday) Fever (11pm the night of the injection, 101.2 at its highest, fever broke around 5am the following morning but returned Sunday night and hit a high of 100.8) Body aches Chest fluttering (the night of the injection) High heart rate Nausea (the night of the injection) Swollen lymph nodes in left armpit (Sunday evening) Headache

Received shot at 2:45pm. Sore/stiff arm started around 6pm. Went to sleep and woke up at 1:00am shaking with a fever and chills. Severe headache, throat sore with swollen glands, could barely walk/move or get out of bed. Also experienced nausea. Took tylenol around 1:00am and again at 5:00am. Could not move from bed on Wednesday and had to call out of work Thursday with a bad headache, weakness, and overall body pain/discomfort. It is now Friday and I am still having very bad joint and muscle pain when I walk and move and still have a headache and fatigue/weakness.

It?s been over a week and I still have a red circle and swelling from where the shot was given. The itchy part of it finally went away.

I received my second dose of the Moderna COVID vaccine at approx. 10:40 AM on Friday, January 29 at clinic. By 12:00 PM, I noticed that I developed facial swelling, which was most significant around my eyes, and I felt lethargic. Between 12:00 PM and 2:00 PM, I developed hives on my neck, chest, stomach, and arms, which prompted me to take 1/2 of a dose of 25mg Benadryl. Nonetheless, the symptoms persisted and I began to experience dizziness and tightness in my throat around 4-5 PM, which was when I was advised by a nurse to go to the emergency room for treatment. I arrived at Hospital's Emergency Department around 6:00 PM and I was treated for "Possible Allergic Reaction Major." I received diphenhydrAMINE (BENADRYL) injection 50 mg, famotidine (PF) (PEPCID) injection 20 mg, methylPREDNISolone sodium succinate (PF) (SOLU-MEDROL) injection 125 mg, sodium chloride 0.9 % iv bolus, and acetaminophen (TYLENOL) tablet 650 mg. I was discharged after 10:00 PM and sent home with a prescription for predniSONE 20 mg and famotidine 20 mg. My facial swelling and hives have gone down but neither have completely resolved since being discharged. I am also experiencing full body aches and fatigue at this time (3 PM on Saturday, January 30).

1/29/21/after vaccination reported "numbness and tingling around her mouth and lips area and described it as feeling swollen. Pulse 80, breathing unlabored and red cheeks." reported neck pain in the back left which was similar reaction after 1st dose. She also reports having congestive heart failure. Observation for 20mins no swelling noted on mouth, tongue or lips. reported tingling has subsided. She was instructed to call doctor if symptom worsened and to return to ER. She stated that she text her heart doctor . Pt left with mother.

1. Swollen lymph node in left armpit - started approx. 6 days after the injection 2. Mild rash on upper left arm, occasionally itchy, about 2x3 inches in size - started approx. 11 days after the injection

1/4/2021 vaccination Almost immediately, i felt really dizzy and lightheaded. Couldn't feel my feet. Lasted for about an hour, monitored by EMTs. Went home, slept and woke up feeling better. Soreness at injection site, lymphnodes were swollen; lasting about 24-48 hours.

Red rash over both arms to her back. Her arm doubled in size, fever, Couldn't move arm. Rash is still on her arm. Her doctor told her to use benadryl 25 mg three times daily.

Started as a radiating pain to finger tips and into left chest (felt like a heart attack) night one, a few hours after vaccination a bright red circle appeared about an inch in diameter and continued for 72 hours, the turned purple for the next few days. 7 days later spot on arm is purple/red, raised and itchy. comparable to a bug bite

Moderate pain in injection site for first two days (02/02/2021, 02/03/2021). Nausea, lower back pain, knee pain, sore throat, low-grade fever (~99°F) and persistent headache, and took Theraflu nighttime before bed on day two (02/03/2021). Temperature of 99.7°F throughout day three (02/04/2021); also, lower back pain, knee pain, sore throat with swollen lymph nodes and tonsils with white spots (did at-home test for strep-A, got a negative result), and persistent headache?this night I also took Theraflu nighttime. Day 4 (02/05/2021), I woke up around 7AM with severe nausea and went back to sleep after having ginger ale; throughout the early afternoon I had mild lower back and knee pain, same throat and tonsil situation, mild headache, and diarrhea. I ended up drinking a lot of water and had a glass of emergen-c as well as taking two pepto bismol tablets. Less than an hour later, I threw up everything I?d consumed throughout the day (water, hot tea, and emergen-c, no food due to nausea). Tried eating plain white rice and drinking beer that evening but I couldn?t keep it down. Day 5 (today, 02/06/2022), I woke up with only lower back pain, same tonsil/throat situation, headache, and a slightly higher fever- 100.2°F. So far no nausea.

On the day of the vaccine, I only experienced arm soreness. I took Aleve at approx. 1:30 pm and 11:30 pm on 2/4. I woke up at approx 4:45 on 2/5 covered in sweat, nauseous, headache, and swollen lymph nodes. I did not work on 2/5. I took Tylenol on 2/5 and 2/6. I felt better around 7pm on 2/6 .

101.4 F fever at 11am, day after injection. The following day was 99.4 F degree temperature. Use of Tylenol managed to lower the fever. Swelling at injection site, limited mobility in arm due to soreness and swelling, which has recovered. Swelling has gone down. Arm soreness has gone down but not entirely faded.

Started with underarm/side of body swelling and pain to touch on side I was vaccinated on, on 1/23. Progressed to full body soreness and swelling. Some burning to touch on underarm skin. Symptoms subsided by 1/28

Vaccine given in L deltoid. Arm swelled and became red with throbbing pain. Also developed fatigue, body aches, nausea, and HA. which resolved within 24 hours. However, arm pain/swelling/redness lasted 48 hours. Resolved partially with 50mg Benadryl and 800mg IBU.

Moderna COVID-19 Vaccine EUA I was in the shower at 5:45pm when my left arm began to itch. I scratched my arm a few times. Then, I looked at my arm and noticed that it was red. There was a red area in the exact place where I received my Covid vaccination 8 days earlier. There were also red scratch marks from where I itched the site. A few minutes later, the itching had subsided, but the red mark was still visible. I got out of the shower and took pictures of this mark. The mark was on my left arm, where I received my Covid vaccination, and was in the shape of a defined square/oval. At the time of this report, it has been approximately 3 hours since I first noticed this reaction. At this time, the red mark is still visible, but the it does not itch. The red mark on my arm looks similar to images of "Covid Arm" I have seen reported online. Additionally, a few days (1-3 days) before this reaction, I had the feeling of discomfort in my left armpit. From my personal experience, this feeling was consistent with the feeling of a swollen lymph node under my armpit area. I felt this feeling for approximately 1 day total. I thought nothing of the discomfort at the time. The uncomfortable feeling in my armpit subsided approximately 1-2 days before the skin reaction on my arm occurred. I do not know if these events are related, but they occurred in the same arm (left arm) where I received my Covid vaccination.

Employee states that adverse events started on the second day after vaccine( Feb. 9th) and they continue to persist as of today. She has following symptoms: Hives on the left arm (injection site), face is swollen, upper lip is swollen, mouth is really itchy, chills, sweats.

The pain is in the anterior aspect of her bilateral legs right> left. Of note, pt did have some left sided axillary LAD that started 5 days post vaccine and resolved spontaneously 3 days later. Pt also has some tenderness in the extensor surface of her right arm. Denies overlying skin changes.

I have swelling, redness, itching, and my arm is hot to touch. I have a rash from my injection site to up my arm. I noticed it yesterday and I went to the doctor. They told me it looks like a localized reaction and to take an antihistamine for a few days.

painful, erythema, swelling, knot on left arm. Dyspnea, chest tightness, wheezing, feeling of swelling in throat, struggling to breath on the 6th and went to ED. Fever 104. CT scan, ultrasound of arm, Oxygen and nebulizer treatments beta agonists, +diphenhydramine. Prednisone+azithromycin+benzonatate+prn rescue inhaler (albuterol). As of 2/22 still using treatments and still having symptoms as an outpatient. Assessment for emboli.

My left arm was super sore and then I noticed a lump in my left clavicle area that moved from either side of my clavicle and super uncomfortable. I also had a lump in my left arm pit that didn't move but was super tender.

Debilitating pain in left arm (the one that received the shot). Difficulty lifting or using it. Started roughly 2 hours after vaccination and lasted for 2-3 days. Swelling in lymph nodes in left armpit. Started about a week after vaccination and lasted for 2-3 days. There is no personal history of swollen lymph nodes in armpits.

patient woke up next morning with cold sweats and headache. also had swollen arm, red bullseye around shot spot, blurry vision and metallic taste in mouth

Six hours after first dose there was arm pain and hotness. Overnight, I woke up with sweats and my whole arm was throbbing and hot to the touch. The next morning after the dose (18 hours after) I experienced headache and dizziness as well. Arm pain lasted 3 days then subsided. I also experienced pain in my armpit. On 3/6/21 , 8 days after my first dose, my arm began to hurt again and now it is inflamed and there is a rash at the injection site. Armpit hurts again as well .

Lymph node swollen under left arm (injection arm) starting on day 5 after vaccine and lasting at least a week

Moderna COVID-19 Vaccine EUA I received the vaccine on 3/13 at 3:45pm and began experiencing symptoms on the day at 5:30pm including dizziness, nausea, fatigue and wiped-out exhaustion, drunk-like dazed and confused, body heaviness, and developed soreness in the muscle of the right arm where the injection had been administered. The symptoms progressed at 6:30pm to include general muscle soreness, muscle twitching on the right side of the body especially on the right upper thigh, increased appetite, malaise, headache, and chills in addition to the aforementioned symptoms. At 7:30pm the nausea and increased appetite improved with food and fluid intake but sleepiness, yawning, confusion, chills, and fatigue worsened at 8:30pm. Temperature at 9:30pm was 95.7 degrees Fahrenheit and a pale, green-like, clammy appearance was visible on the general skin. At 10:30pm the sleepiness reversed to restlessness and insomnia to the point of hyperactivity, and the appetite increased four-fold along with rash up and down the injected arm, numbness and tingling in the injected arm, chest discomfort with palpitations, anxiety, headache, stomach pain, malaise, and general limb edema which all persisted until I was able to fall asleep at 6:30am on 3/14. Many of the aforementioned symptoms improved upon wakeup time at 4pm on 3/14, but extreme sleepiness with nausea, dizziness, fatigue, head pain and right eye pain, and palpitations with chest discomfort persisted until 10am on 3/15, during which time only the nausea, dizziness, and fatigue persisted.

For first shot on 2/5 R arm, developed a red rash type thing on my arm. As time went on (weeks) the redness grew bigger and looked like a welt. Arm was very sore, hot to the touch, and swollen for nearly 3 weeks following the injection. Second shot on 3/5 R arm, also developed a small red rash but was smaller and went away within a week. Within 24 hours of getting the vaccine, a high fever developed, fatigue, weakness, nausea, pain throughout my body, and migraines.

Abdominal pain, nausea, vomiting, low grade fever, headache, body-aches, fatigue, joint pain, jaw pain, sharp chest pain when breathing and swallowing, etc. Was seen in hospital ED on 3/14/2021. Covid-19 tested negative on 3/14/2021. Missed work two days.

Swollen lymph node in left armpit approx. 5 days after vaccination. Continues on 6th day (today). Achy and discomfort when moving arm or touching armpit.

swollen and painful lymph nodes in collarbone area and under armpit, both on the side of the injection

My arm began to hurt at the vaccination site, with a red spot. It was like a knot and itchy. By today my whole upper arm is tight and swollen and a very large red spot around it like the size of a credit card.

Anaphylaxis; Rash all across her leg; Swelling; Itching; Red; Hot; A spontaneous report was received from a consumer concerning a 22-years-old female patient who received Moderna's COVID-19 vaccine (mRNA-1273) and experienced events anaphylaxis, rash all across her leg/rash, swelling, itching,/pruritus, red/erythema, hot/feeling hot. The patient's medical history was not provided. No relevant concomitant medications were reported. On 05 Mar 2021, prior to the onset of the events the patient received first of two planned doses of mRNA-1273 (lot/batch: 030M20A) Intramuscularly on right leg for prophylaxis of COVID-19 infection. On 10 Mar 2021, the patient experienced the event(s) anaphylaxis symptoms of swelling, itching, rash all across her leg. It was red, and hot.S he was a very fragile person with many syndromes and so they took her to the doctor. She was feeling better on 14 Mar 2021. Treatment for the events were none. Action taken with mRNA-1273 in response to the events was not reported. The outcome of event(s), anaphylaxis, rash all across her leg, swelling, itching, red, hot were reported as recovering on 14 Mar 2021..; Reporter's Comments: This case concerns a 23-year-old female who experienced a serious expected event of anaphylactic reaction along with unexpected rash, erythema, pruritus, swelling, and feeling hot. Event onset occurred on Day 6 after the first dose of mRNA-1273. Treatment not reported. Events resolving. Based on current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.

I received a BCG shot about 2 decades ago. I have a small scar on my arm from this shot. After the covid vaccine, the scar on that arm got red/swollen. It is the second day and it is still red. I have no redness where the covid vaccine was administered, just redness where the scar from my bcg shot is. Is this sone kind of reaction?

Red swollen and hard area around injection site, started two days after vaccine and is still ongoing fatigue headache lasting two days muscle spasms and twitching around injection site swollen lymph nodes in the neck on the same side as injection

Day 1: Sore arm Day 2: Sore arm Day 3: back to normal Day 4: armpit pain and palpated lump in armpit Day 5: worse armpit pain radiating into arm, neck, chest and back Day 6: same pain as day 5 Day 7: extremely severe pain in armpit, palpated larger lump. The pain is more extreme in my arm and neck.

moderate headache starting after 5 hours lasting 9 hours. Sore neck starting after 7 hours subsiding over 20 hours. swollen axillary lymph nodes starting 3 hours after lasting over 24+ hours. Sore arm 15 minutes after injection, increasing in severity before decreasing over 24+ hours. Sore injection site immediately lasting 24+ hours. Fatigue starting after 1 hour lasting 24 hours. No NSAIDs taken.

Injection itself was painless, but sharper more persistent pain developed several hours after injection and worsened into the night. Arm swelled significantly over the night and is painful to move at all.

The night of my vaccine, I had a 100 degree fever, body aches, and chills. That was resolved by the next day. On 3/29, I woke up with itchiness behind my right ear. around 4:30pm on the same day, I had broken out into hives on my face and arms. By 5:30 they had become itchy and had spread to my neck and chest area. I had also developed swelling around my eyes, above and below them. I woke up at 1:30am on 3/30 with itching and burning and more swelling around my eyes. At 7:30am on 3/30, my eyes were almost swollen shut and I sought medical attention. I had itching and burning on my entire body, swollen eyes, full body aches, and joint pain. I was prescribed steroids and began that course around 1:30pm. I was also prescribed two epi pens. Around 6:30pm that night, I had a 100.7 degree fever. It dropped without the use of a fever reducer within the next two hours. The swelling reduced around my face by 8pm. This morning, I had almost no swelling, but still a full body rash. I am treating it with benadryl, zyrtec and maximum strength pepcid, steroids, and calamine lotion.

5 minutes after injection I experienced light headedness. An hour after it turned into a brain fogginess feeling where I feel like I am high constantly. It feels like I am not as alert, pressure on forehead, unbalanced/dizziness, slight headache, major fatigue, eyes feel strained, etc.

Rash around injection site, as well as on chest. Swelling of lymph nodes in left armpit (same arm used for vaccine)

Circular swelling approx 15cm, red in color , occasional rash flare in area mainly at night . Nasal congestion, coughing, sore throat, hot flashes.

Systemic: Allergic: Difficulty Swallowing, Throat Tightness-Medium, Systemic: Allergic: Swelling of Face / Eyes / Mouth / Tongue-Medium

i have a ball under my left collar bone. I had covid symptoms friday night, chills fever etc then on saturday night i was fatigued low grade fever and body aches. on sunday when i woke up i felt it stressed and felt the ball.

hot, swollen, red rash that grew from the size of a penny into that of a softball. Happened with both dose #1 & #2

Chills and hot flashes; extreme achiness. Enflamed lymph node above left collar bone, noticed day after vaccine. Continued to grow in size for a week, still present after 5 weeks, but does seem to be decreasing in size.

Allergic reaction. Red, swollen, patch on arm left arm where shot was given. Painful and hot to the touch. Painful to move.

2nd dose Moderna Covid 19, sat in waiting room for about 5 minutes then notified me of rash developing on lower arm, below injection site. Gave the patient diphenhydramine 25mg and had her sit to be monitored. rash continued to worsen, no shortness of breath or other symptoms, just painful, fine, red rash and slight swelling. 2nd dose of diphenhydramine given in liquid form and sent to immediate care clinic with person accompanying.

The night I got the shot, my arm developed a large red spot that swelled up and was very painful. On the 21st I still have the red spot . It is not longer painful but it is still hot

5 days post vaccine patient developed foot swelling/rash. Seen by PCP 4/20/21 for this issue and diagnosed with rash/vasculitis like reaction.

I had fatigue and headache and new to expect that so that was fine and pasted but now that its been a week later my arm is itching again and an red and a little swollen. The skin is tender to touch and just keep itching.

Fever, chills, chest pain lasting 36 hours, hypertension lasting 48 hours, severe lymph node pain and swelling, nausea

About 24 hours after first Moderna Vaccine, on 3/3/21, pt developed fatigue, body aches and vaginal ulcerations/sores. These continued to worsen and spread to a lesser extent to face, upper chest and back on 3/4/21 at which time she was seen in my clinic. Lesions appeared consistent with HSV although was difficult to explain chest/back lesions. Swabs for herpes and shingles completed. Lesions continued to worsen and pt soon developed oral sores. She was admitted to hospital on 3/6/21 and tested for mono, herpes, etc. White count was elevated but no infectious source identified. Treated with rocephin and azithromycin although GC/CT negative. Lesions resolved on their own. Fatigue and body aches have slowly improved.

Painful left supraclavicular lymphadenopathy, onset approximately 6 hours after vaccination. No current treatment. Persisting at this time.

After about 10 days of getting the first shot of MODERNA COVID19 vaccine, I began to feel itchy on my feet starting the night before. Waking up, my feet felt unusually itchy and I checked to see that my feet were swollen with red spots. After half an hour, I began to feel itchy on my elbows and found that there are some swollen spots as well. At first I thought I was bitten by ants or bed bugs but throughout the day, hour after hour, I noticed that there are more red spots arising. Now I have these red spots scattered over the palms of both of my feet, on both sides of my hands, and all over my elbows. They feel itchy and swell larger if I touch them or scratch (accidentally).

Extremely swollen and sore lymph node in left armpit. Began at 10:30 AM on May 5th - worsening throughout the day.

First shot - Only symptom was a sore arm two hours after injection and lasted 3 days. Second shot - Symptoms included sore arm at site of injection, fever, chills, swollen lymph nodes. Arm was sore for on the first day, two hours after injections, and lasted 3 days. Fever (highest was 101 degrees F) and chills started on the second day and lasted ~24 hours. Fever (100 degrees F) persisted on third day. Swollen lymph nodes appeared and were noticeable on the third day on the left armpit (side of injection) and on the left side of the neck.

After 1st dose, fatigue, headache and muscle soreness in the left arm first 2 days after vaccination. After 2nd dose, first few days was low grade fever, muscle soreness and fatigue. 3rd day after small bruise developed at injection site and muscle aches and pains. The bruising on the arm has gotten progressively larger and much worse for the last 7 days. The bruise now extends from just below the shoulder where the injection was given down to the elbow and all the way around the entire arm with moderate swelling. Joint pain in the right shoulder and unable to lift arm more than 6 inches. Bruising keeps increasing everyday.

went into anaphylactic shock, couldn't breathe, tongue swelled up, light headed, legs heavy, slurred speech. Got benadryl shot at 11:49 pm, epipen at 11:58, was prescribed femotidine and prednisone.

Confusion and Amnesia and possibly a simple partial seizure that took 3-5 hrs to recover from. I couldn?t sleep and it felt as if things weren?t real. 2 days later as of today I have facial swelling, dizziness, fever, all over pain, and redness end swelling at injection site

Adverse event: inflammatory reaction in left arm. Extending from base of arm to top of neck. Unable to lift arm. Swollen, red, hot to the touch.- treatment: 6 day course of prednisone and antihistamines. Urgent care advised that second dose could cause anaphylaxis- advised not to receive. Outcome: took 7 days to get swelling to go down, range of motion, pain to go away.

About one week after vaccination, the patient developed symptoms of enlarged cervical LN, sinus pressure, fevers. This progressed to develop rash and eventually SIRS. She was admitted several times over the course of April and May to determine a diagnosis and had extensive workup for infectious, autoimmune and hematologic malignancy. The ultimate diagnosis was macrophage activation syndrome/HLH but it is unclear if this was triggered by the COVID vaccine or not. She is responding to steroids in taper and Anakinra and still recovering in the hospital at this point.

Redness on upper arm around the place that took the dose after take the vaccine for around 9 days. Didn?t take medicine. The redness disappear after two days. The lymph is swollen (and pain if I touch it) on the side that take the vaccine after 9 days after taking vaccine. Then, it recovered after gradually.

Towards the end of April - Beginning of May: Both legs started to become itchy. May6th- May 8th: Started to notice mosquito- bite like bumps on both lower extremities, both legs started to swelled up. But the right leg was more swollen than the left to the point that I couldn?t sleep or walk on it. May 9th- I went to Emergency Care around 5am to be checked out cause it was hurting me so much. They couldn?t figure out what had happened and they discharged me a few hours later with an order of Prednisone to take once a day for 7 days and preferred me to my PCP. May 10th - We went to go see my PCP which she advised us to stop taking the prednisone and doctors orders was to stay out of work for a week in order to be off my feet. She advised us to cancel the second vaccine appointment until everything clears up.

She is 11 weeks pregnant. On 5/19/2021 began feeling pain in her left groin area. Didn't think too much about it. 5/20/2021 swelling and pain in left groin area. Went to urgent care. scheduled ultrasound. Blood clot in Left groin detected. Hospitalized and treated for clot with blood thinners.

feeling like passing out; paleness; injection site pain; she felt tired, exhausted; headache; feeling like a golf ball is under the skin; inability to move her arm above her heart because the pain was so severe. Patient reports inability to use her arm and intense pain when changing clothes; feeling horrible; she couldn't function; she couldn't or eat; wanting to sleep; This spontaneous case was reported by a consumer and describes the occurrence of NEAR DEATH EXPERIENCE (feeling like passing out) in a 23-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 003B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. The patient's past medical history included COVID-19 in April 2021, Narcolepsy, Depression, Anxiety, Loss of smell on 02-Apr-2021 and Loss of taste on 02-Apr-2021. Concurrent medical conditions included Drug allergy (Biaxin) and Drug allergy (Adderall generics-anaphylaxis related to an unidentified inactive ingredient in certain). Concomitant products included PARACETAMOL (TYLENOL), VITAMIN C [ASCORBIC ACID], COLECALCIFEROL (VITAMIN D3), FISH OIL and ZINC for an unknown indication. On 25-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 25-Apr-2021, the patient experienced SWELLING (feeling like a golf ball is under the skin), MOBILITY DECREASED (inability to move her arm above her heart because the pain was so severe. Patient reports inability to use her arm and intense pain when changing clothes), FEELING ABNORMAL (feeling horrible), MOVEMENT DISORDER (she couldn't function), EATING DISORDER (she couldn't or eat), SOMNOLENCE (wanting to sleep), VACCINATION SITE PAIN (injection site pain), FATIGUE (she felt tired, exhausted) and HEADACHE (headache). On 26-Apr-2021, the patient experienced NEAR DEATH EXPERIENCE (feeling like passing out) (seriousness criterion medically significant) and PALLOR (paleness). The patient was treated with CHLORPHENAMINE MALEATE, PARACETAMOL, PSEUDOEPHEDRINE HYDROCHLORIDE (TYLENOL COLD MEDICATION) from 25-Apr-2021 to 30-Apr-2021 at a dose of 1 dosage form. On 26-Apr-2021, NEAR DEATH EXPERIENCE (feeling like passing out) and PALLOR (paleness) had resolved. On 02-May-2021, SWELLING (feeling like a golf ball is under the skin), MOBILITY DECREASED (inability to move her arm above her heart because the pain was so severe. Patient reports inability to use her arm and intense pain when changing clothes) and VACCINATION SITE PAIN (injection site pain) had resolved. On 06-May-2021, FEELING ABNORMAL (feeling horrible), MOVEMENT DISORDER (she couldn't function), EATING DISORDER (she couldn't or eat), SOMNOLENCE (wanting to sleep), FATIGUE (she felt tired, exhausted) and HEADACHE (headache) had resolved. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 02-Apr-2021, SARS-CoV-2 test: positive. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. Patient administered two Tylenol tablets per day from 25Apr2021 to 30Apr2021 to treat her symptoms. Patient reports these symptoms [unrelated to injected site] lasted 10-11 days. Patient reports no previous reactions to any past vaccinations. Patient reports loss of sense of smell and taste on 2Apr2021, which prompted her to get a rapid COVID-19 test, that initially resulted in a negative result. Patient reports receiving a phone call on 5Apr2021 notifying her that upon further laboratory testing of her sample, she was COVID-19 positive. Patient reports quarantining until 11Apr2021. Patient reports she was symptom free by 11Apr2021 when she discontinued isolation. Company comments: Based on current available information and the temporal association between product use and the start date of the events a causal relationship cannot be excluded.; Sender's Comments: Based on current available information and the temporal association between product use and the start date of the events a causal relationship cannot be excluded.

Extremely swollen lymph nodes in armpit. Same arm where shot was given. Severe pain and tenderness on the armpit area.

On the second day of the MODERNA Vaccine, patient felt itchiness on arm. On third day, patient indicates that it became inflamed, or woke up with face swollen, and one eye was very swollen

Approximately 24 hours after getting immunization she had a reticular rash on the entirety of her left thigh and pain in the inguinal lymph nodes. Nearly resolved 24 hours later.

I got swollen lymph nodes on my shoulder and collar bone on April 18, 2021, 6 days after my Covid-19 vaccine (second dose). I went to the doctor, and they did blood work. I also got an ultrasound done. I still have a couple of the lymph nodes on my collar bone. They're much smaller now, but I will be going back to the doctor to get them looked at again.

Swelling of lips and face that progressively got worse and spread to half of my nostril. Swelling started on the lower left lip with a heavy feeling on April 13th and spread to the whole upper lip on April 14th. Pictures available with progression.

I am having major stomach pains, it's like very painful gas and cramps. I am too nauseous to eat or move, really. My arm hurts so much it feels like if I pick anything up (like my phone, or a blanket) with my left arm, I get this shooting, tearing pain all through my upper arm. All the joints in my left arm have sharp shooting pains along with just general stiffness. I also had tingling in my fingertips & some major swelling all through my upper arm and shoulder.

3/20/21: All over body rash, toes on right foot turned blue, itching, swelling went to urgent a care. Rash became worse over following days. Went to emergency room 3/23/21 when throat felt strange when swallowing

Second dose. Pt is severely intellectually disabled at baseline but can walk. W/in 12 hours had fatigue and sleeping 2- hours per day. W/in 5-7 days had legs collapse, can't walk, severe pain in legs/feet, tremors, myoclonus. Has feet swelling and is losing hair. Responding to time and GPN + Doxepin. My working diagnosis is auto-immune small-fiber PN. (Variant GBS)

3 days of muscle pain and fatigue. Day 6 had severe collarbone area pain and found a hard inflamed lymph node same side as vaccine. Now day 9 continuing lymph node pain plus a large hot, red, painful swelling 3 1/2 inches in diameter located 2-3 inches below the injection site. My entire arm is a dull ache

When getting the vaccine, person giving shot didn?t make sure needle was screwed onto syringe completely. When needle was in arm and plunger was pushed, contents of vaccine went all down arm. A second injection was given in the same arm. 8 days later, I woke up to swollen, hot red arm at injection site. A swollen and hard lymph node was also felt underneath armpit of the injected arm

Started getting a localized allergic reaction on the Left arm near the injection site. Arm became red, swollen, and itchy.

ErythemaMultiform, UrticariaPruritus, also swollen lymph nodes, tightness, painful, tender to touch and some movement on injection site armpit Narrative: 5 days post vaccination swollen lymph nodes on injection site armpit. tightness, painful, tender to touch and some movement on injection site armpit. No treatment used. Erythema and itchiness at injection site as well. Hydrocortisone 1% PRN applied to area.

Swelling in arm , redness in upper arm towards injection site , tenderness , extremely hot to the touch, headache

On the morning of 1/8/2021 (exactly 6 days after the first dose of the Moderna vaccine), I woke up with large hives concentrated mostly on my upper body (face, neck, chest, stomach). I tried taking various antihistamines (excluding Benadryl, which would later prove effective) to combat the hives, but they were largely ineffective. The hives shifted throughout the day, starting in my upper body and working their way down to my lower extremities. The next day, exactly one week after receiving the vaccine, I woke up with worse hives (now all over my body, mostly concentrated on my stomach, hips, and legs) and angioedema in my face. At this point, I went to the hospital and received a course of IV fluids/steroids/Benadryl/anti-nausea medication and all symptoms subsisted. Symptoms returned a few hours after discharge, where I continued an oral regimen of the aforementioned medications. The next day, 8 days after the initial dose, my symptoms were equally severe and coupled with gastrointestinal distress, feverishness (likely due to dehydration from the Benadryl) and nausea. This morning (1/11/2021), 9 days after receiving the vaccine, my hives have largely subsisted. In summation, starting 6 days after receiving my first dose of the Moderna vaccine, I experienced 3 full days and nights of severe hives and swelling.

1 hour after vaccination client complained of dizziness, swelling of right hand. No general s/s of anaphylaxis noted. Pt was given juice, crackers and asked to rest in recumbent position. Symptoms did not improve and 12.5 mg of benadryl IM given in opposite arm of injection. After 15 minutes same general symptoms present; another 12.5mg of benadryl IM given again in opposite arm of injection. Pt remained lying down and 20 min after 2nd dose of benadryl patient reported feeling improved and able to ambulate independently. And monitored in her workplace without further intervention.

on the 8th she started feeling swelling in her arm pit. Felt like an eternal blister. Could barely lift her left arm.

On 1/5/21 arm became swollen, red and hard. She saw her PCP on 1/7/21 and she was started on Prednisone 40 mg for 5 days. Arm is improving today, 1/12/21

Patient reports 7 days post vaccination raised, hive-like area. w/o pruritis that flattened over time and now presents as reddened area. Pt did not take any Benadryl for reaction. Pt concerned about second required series due 1/30/21 to where she will rcv medical advice.

called to Car after vaccine due to patient not feeling well. Quick history obtained: No pmh. Not pregnant per patient. nly allergy to milk. No history of anaphylaxis. She received vaccine at 5:42. Felt lightheaded and dizzy about 5 to 10 minutes after the vaccine. She noted chest tightness and tachycardia symptoms. We transported her via gurney to our observation area. She looked sleepy and had trouble arousing her. Blood pressure is 140/80, heart rate was in the 90s to 100s. Breath sound decreased bilaterally. No lip swelling. No rash. She noted throat felt uncomfortable. Suspect anaphalxis reaction given rapid decline in status while talking with her. epic pen at bedside immediately and then due to increasing heart rate and complaints of chest discomfort gave her epipen times one. Paramedics were called prior to decision for Epipen. She noted after a minute or two her chest felt better. Monitored her and blood pressure remains stable 140/80's, heart rate initially increase to 110 and then back down to 100 about 5 minutes after the first dose. Second dose of EPI readied as Paramedics not on site yet. At about 8 minutes from EPipen dose her heart rate increase to 160 and she noted additional symptoms of chest tightness again and re-gave a second Epinephrine pen. She was more somnolent but protecting airway. Oxygen was added 2 liters after second epi pen. Her sats dropped right around second epi pen to 94% but about 2-3 minutes later back to 98%. Paramedics arrived 5 minutes after 2nd epi dose and care was transferred to them. She was transported in stable condition. Once paramedics arrived it was determined that they got a level 3 request which was not as urgent and this should have been a level 1. We reviewed how this happened and they note that our site was listed as a level 3 site due to having staff on hand. We were advised to ask for LEVEL 1 paramedics in futures. This was communicated to all Medical staff as well as the Physician of the day orientation.

On Friday January 8th (1 week following the vaccine injection), my left arm at the injection site became very hot, red, painful, and swollen. There was also tenderness and pain in my left axillary lymph nodes. The swelling and redness continued until 1/13/21 until it started to dissipate. On 1/15/20 I woke up with a sore throat on my left side.

Moderna COVID-19 Vaccine EUA. Approximately 10 hours after injection, the following side effects/symptoms occurred: body aches, joint pain, headache, uncontrollable shivering, chills, fever, night sweats, severe injection site pain, weakness, dizziness, fatigue, swollen lymph node on side of injection, loss of appetite, difficulty moving body due to pain. 24 hours following, a majority of the side effects dissipated except for severe injection site pain and general malaise/weakness

Pain and swelling at injection site on the left arm as well as pain in the left axillary lymph nodes which started about 5 hours after the injection. Pain lasted 3 days and the swelling is improving on the third day. I also experienced 1 day of muscle aches and fatigue on the day after the injection.

Initial 3 days: Tiredness, head ache. 7 days later: Itchy at injection site and redness/a hard-ish bump at injection site. Lymph node under left armpit feels tender for 3 days.

Swelling of supraclavicular lymph nodes, cervical lymph nodes, axillary lymph nodes, and inguinal lymph nodes. Larve and very painful.

Arm began to swell and turn red a week after dose was given. Pain also continued in arm (burning, soreness)

Noticed swelling and redness 8 days after dose. Itching at injection site as well. Redness is improving, rash it new, and swollen.

24yo F with hx of sulfa allergy received the Moderna Covid vaccine on 1/4. Day 1 felt chills, feverish. Reports edema in limbs, face, hands and whole body ("swollen to twice it's size). Tingly lips, extreme headache, nausea and body aches. Reddish urine for 4 days following. Swelling subsided after a few days.

Chills, myalgia, nauseous. A red, swollen, and raised mark developed on 01.20.2021 and it tripled in size by 01.21.2021 to 3 inches in length and 2 inches in width.

Extreme pain at and around site within 3 hours. Difficult to use right arm, severe soreness with throbbing aching pain. Total body muscle pain at 12 hours after delivery. Unable to sleep due to uncontrollable shaking and could not lay on injection site. Nauseous, High fever, Swelling, Redness, Fatigue and lack of focus.

At approximately 6 AM upon waking up I felt lethargic and soreness at the injection site. Also had hives around the shoulder and neck and chest area. And also swelling in the face and extremities (hands and feet). This lasted all day on the 22nd. Ibuprofen and Benadryl did seem to help.

Moderna COVID-19 Vaccine EUA Received vaccine IM on Left arm on 1/16/21 at 6:30 pm. On 1/22/21, woke up with a swollen, tender and painful armpit that is hard to move.

dizziness, headache, diarrhea, arm redness, faitgue. Used Ibuprofen and iced arm. Reports being fine now.

11x13cm redness and swelling left arm--onset day after vaccination and has grown over next 11 days. Last contact 11 days after vaccine

On 1/24, severe axillary lymph node pain occurred ipsilateral to injection site and has been continuous. On 1/26, 1in x 2in swollen, smooth, rash formed near injection site.

Facial flushing, bilateral upper arm swelling and erythema. Patient was treated with Claritin, Benadryl and Medrol.

Large swollen itchy red blotch on arm, slightly overlapping bruise at injection site; noticed 6 days after injection

~24 hours after the vaccine, I got a mild rash on my face. This rash went away in about 12 hours. The rash was itchy and hot, but didn't last long. After this I noticed I would get stomach pain intermittently. This has not gone away yet (today's date is 1/28/20). The stomach pain has been intermittent, not related to certain foods, and hurts sometimes when I don't even eat. It has progressed into getting severely bloated every time I eat any foods. The bloating lasts ~1-2 hours after consumption. No matter how big or small the meal or snack is, or what the food is, it results in me being bloated.

Initial adverse event occurred 25 minutes after injection. Sudden confusion, burning heat and hives and burning red rash spreading from injection site, up neck and throat and down arm to hand. 5 days after the injection, a severe allergic reaction occurred where my entire body broke into hives and a red burning rash, again starting at the injection site. Throat tightness, itchiness in scalp and groin, and difficulty concentrating (all my usual symptoms of anaphylaxis) occurred. Advised by health care provider to take Benadryl immediately and to have epi-pens on hand. Loratadine was prescribed.

Moderna COVID-19 Vaccine EUA Swelling and stiffness in right armpit and right latissimus dorsi, with tingling/numbing sensation through to the fingers in the right hand (primarily third and fourth finger). Symptoms began 48 hours after the injection of the second dose. There has also been nerve problems in the left arm starting on 1/27, about 22 days after the first dose of the Moderna vaccine taken on 1/5, in the left arm. Loss of motor function and clawing of the fourth and fifth finger resulted in the left hand. As of 2/1 motor function returned, however forth and fifth fingers are still not able to enforce resistance against external pressure. The lot number of the first dose is #025J20-2A

I had a headache, extreme fatigue, nausea, aches, fever, and chills for 24 hours beginning at 8:00pm the day that I received the vaccine. I had a burning sensation and lypmhadenopathy in the armpit of my injection arm, significant pain at injection site, with slight tingling and numbness radiating down to the hand of my injection arm as well. I took 1,000mg of Tylenol every 6 hours for 24 hours, which provided minimal symptom relief. All symtpoms were relived within 72 hours of receiving the vaccine.

I got the first dose of the Moderna COVID-19 vaccine at 3pm 1/13/21. I was fine for the 30 minutes after, not even sore at the injection site. Around 6pm, my muscles started aching, but not painful enough to be concerned. At 3am 1/14/21, I woke up in pain in every muscle. Enough to wake me, but not terrible. At 7am, I noticed a pinpoint pain in my armpit, and my muscles still ached. At 9:30am, I took ibuprofen to attempt to curb the pain a bit. Around 10am, it got so painful I was limping, and having trouble bending down or reaching above shoulder height. At 11:30am, I noticed the pinpoint pain in my armpit had gotten worse, and there is a hard, approximately quarter-sized round lump in this spot. Very painful. At 2:30, I went to move my shirt sleeve and the pain at the injection site was so intense I screamed when I touched it. This pain continued until 1/16/21 when I woke up feeling entirely normal. Since 1/16/2021, my hands have been randomly stiffening, either completely stretched out and dropping anything in them, or closing tight enough to leave fingernail marks on my palms. I will also reach to grab things and my hands will sometimes bend into odd shapes, instead of what I intended for them to do. This began at 1-2 times a day, and is becoming more often. It is now up to 2-4 times daily.

Under observation for 30 minutes after vaccine due to history of anaphylaxis after a previous vaccine. No problems until about an hour after injection experienced swelling and itching in throat, tongue and jaw. Seen at ED and given steroids. Following week still having intermittent tongue and throat swelling/itching, as well a diarrhea and chest tightness. Referred to PCP for further evaluation and guidance regarding receiving second dose.

On January 21 I received my first dose of Moderna vaccine on my left arm. After the vaccine I had a red lump that was hot and a bruise that only lasted 2 days. Everything was fine until the January 28th when I developed a large red lump during the day while at work that was severely itchy and hot. When I got home from work I had a low grade fever. I made an appointment with my primary care for the next day which was Friday the 29th. My doctor told me she believes I had cellulitis. I was given an antibiotic 2x a day for 7 days. She drew a purple circle around the area and told me that if it goes outside the marked area or I feel any new symptoms, to go to the emergency room. Saturday morning on the 30th i woke up to my entire arm red and hot. I felt like I had a huge sunburn. I couldn?t put my sweatshirt on because it was so hot. The emergency room doctor told me I was fine and to keep taking the antibiotics that were given to me yesterday from my primary care doctor. After the emergency room I went to work and started to feel dizzy and nauseous. My hands became sweaty but the rest of my body was cold. I started having a butterfly feeling in my chest. My Apple Watch alerted me that my heart rate was over 100 bpm. That night before bed I had another low grade fever. On Sunday the 31st I noticed the red area was gone but instead it was a dark purple. I felt okay Sunday besides a rapid pulse. Monday February 1st I woke up out of a dead sleep sweating, butterfly feeling in my chest and dizzy. I tried to take my pulse while laying down but it was so fast I couldn?t keep up with it. I put my Apple Watch on which alerted me immediately that my pulse was 152 bpm. I slowly got up but then I passed out falling off of my bed. I couldn?t get any words out because my heart was beating so fast that I couldn?t breathe. I was sweating horribly and had a hard time walking. Had absolutely no strength in my left hand, my arm was purple/red, cold and numb. My arm felt like someone punched me repeatedly and gave me a dead arm. I called my primary doctors office and they were able to get me in that afternoon. All morning my pulse was spiking and then drastically dropping. About an hour and a half before I went to the doctor everything was fine. I was able to talk but still struggled with breathing while talking. The doctor ordered an EKG which came back clear. My pulse and blood pressure was also fine. The doctor told me she believed all of the symptoms I had were from the medication I take at night (doxazosin-to relax my muscles and help with sleep.) She also told me she believed some of it was my mental health issues taking over. She told me the cellulitis looked fine and sent me home. Later that day I felt exhausted and when I woke up from a nap, I had a fever of 100.5. Took Tylenol and it dropped to 99.5 but wouldn?t go any lower. February 2nd I woke up to a large red ring outside of the purple marker, numb finger tips and butterfly feeling in my chest. All day I received alerts that my pulse was falling and spiking. I sent my primary doctor an email and she told me she didn?t think it was cellulitis anymore, maybe a hematoma but she wasn?t sure. Since January 28th I still struggle everyday with the butterfly feeling in my chest, blurry vision, low grade temps, alerts of pulse, dizziness and breathing difficulties. My arm is always hot, my finger tips are numb and sometimes the strength in my hand is gone. The top of my arm is always a dark purple with red blotches and other times my entire arm is red and hot. When my pulse is very fast, I have a hard time talking, remembering what I was going to say and focusing. I?ve had multiple coworkers ask me if I?m okay because I?ll randomly stop talking and stare off and then I?m alerted that my pulse has either spiked or dropped drastically after spiking. My pulse is never consistent. It is always ranging from 57-155bpm. I realized at first I may have what they call ?COVID arm? but my symptoms haven?t gotten any better. No answers have been given to me or a diagnosis. The first diagnosis that they thought was cellulitis. Then it was ?in my head and behavioral.? Then it was a hematoma. Now it?s an ?I don?t know.? I have tried Benadryl for the itching, ice packs for the days that I?m swollen, Tylenol for the fevers and pain but I never have any relief.

Swollen and achey lymph nodes under left arm starting on 2/4/21 and continued to worse up to today, 2/7. On day of 2/7 started experiencing flu-like symptoms, headache, sore throat, and red, raised, and hot patch of arm on injection site.

1 week after before bed I noticed some mild itching at the location site. The next morning I woke up with a rash about 2.5 inches in length and width. It was splotchy patches of slightly raised red skin and mild itching. It has been self-resolving within 24-48 hrs.

Pt received dose #2 Moderna COVID vaccine 2/2/21 @ Vaccine Clinic. Initially had some arm soreness, headaches, and malaise. 2/3/21 starting having chest tightness worse with deep breaths and exertion. Has also had low-grade fevers. Has some coughing with deep inspiration. Some mild nasal congestion and chronic throat pain/irritation. Taking Tylenol 1000 mg two hours PTA. 2/4/21 @ 1849 presented to Urgent Care for workup. Mild bilateral anterior cervical lymphadenopathy. Per provider "Symptoms are likely adverse effects from the COVID vaccine." Discharged home without escalation of care. Entered for tracking.

Moderna COVID-19 Vaccine EUA Painful, swollen lymph node in armpit of vaccinated arm. Pain began evening of day 5 post vaccine, swelling noticeable (difficult to wear usually loose Tshirt without pain and discomfort in the armpit region) evening of day 6 post vaccine. Pain treated with 400-600mg of IB Profen as needed for pain. Swelling diminished evening of day 8 post vaccine. Pain diminished evening of day 9 post vaccine.

12/30/2020 mild nausea all day, limited range of motion in left shoulder, uncontrollable shivering (600 mg Motrin 4:30 pm/ 800 mg Motrin 11:30 pm) 12/31/2020 arm soreness very uncomfortable, nausea most of the day 1/1/2021 9:00 am rash on chest, right and left forearm used hydrocortisone cream and it subsided. 1/2/2021 Itchy all day, nausea and diarrhea 7 pm through out night, mild rash all over body around 11 pm 1/3/2021 felt fine all day 1/4/2021 Felt very sensitive left side supraclavicular lymph node, very prominent, sore throat, headache 1/5/2021 Saw doctor at work place clinic regarding lymph node. Determined to be about 1 cm. CXR, CMP, SED RATE, CBC all fine. GI consult ordered. 1/6/2021 low grade fever 99/2-99.9 gone by 1 pm. **No new symptoms after 1/6, but lymph node is still swollen today 2/9/2021** 1/12/201 Colonoscopy and EGD, no biopsy, no concern 1/20/2021 Breast exam done at gyn office (family hx of breast cancer), ultrasound ordered of left supraclavicular lymph node 1/21/2021 Ultrasound done-results normal

The day after receiving the vaccine, my mouth and my face broke out in cold sores. I had my doctor call in Valaciclovir to help me get rid of them it was so bad. I took the Valaciclovir the day after my vaccine, on 1/16/21 and I was STILL breaking out in new cold sores a week later and had to take another dose of Valaciclovir. My arm was so sore and I couldn't move it higher than my hip for two days. I was lethargic for two days and slept for a total of 40 hours over the course of the two days following injection. I also had a headache for about a week after the injection.

started with headache and sore throat, then high fever (103) a few hours after first symptoms. body aches, chills and vomiting.

Had previous COVID-19 infection following an exposure to a confirmed case in early December 2020, during which my symptoms were classified as moderate in severity. On 2/4/2021, received 2nd dose in the series at 11:40am, no acute adverse events in the 15 minutes post-vaccination and returned home. At 3:00pm that day, developed noticeable fatigue, myalgia, nausea, experiencing 1st episode of vomiting at 3:20pm. On 2/5 at 1:00am, woken up with new onset fever (102.2F), chills, rigors, sweats, systemic joint pain, skin sensitivity, left arm pain and prominent axillary lymph node swelling. On 2/6 at 2:00am, headache onset, Tmax now 102.7F. On 2/7 at 7:30am, woke up with minimal arm soreness, resolution of other symptoms

Fever, chills, nauseous, sore muscles, swollen lymphnodes, ear ache, swollen/sore throat, eyes swollen

The first vaccine I only had mild arm pain which went away after a few days, exactly 7 days later I had a delayed localized reaction (extreme swelling size of a golf ball, redness, itching, hot to the touch). I spoke with my primary and he recommended to still get the second vaccine. The second vaccine the swelling came on almost immediately (about 2 hours after). It has now been two days since I have had the shot and my arm is now double the size of my muscle. (I am petite, 5?3 and 107 lbs) so my arms are tiny. My arm is red, hot to the touch, swollen and itchy. I have had a fever of 102.8, the lowest I have gotten it down is 101.2 with around the clock Tylenol. Other side effects: vomiting, chills, high fever, EXTREME joint pain. I?m concerned about the localized reaction (I would call it localized allergic reaction). I have photos I?m not sure if I can send them.

On 2/5/21- Patient reported getting her 1st moderna COVID vaccine. 1 hour after the vaccine she developed "tingling throughout" her body. 3 hours later developed fever, nausea, dizziness, tachycardia. On 2/6/21- She woke up reporting facial swelling and swelling to her eyes and lips. C/o chest tightness, soreness, and rash on her chest and shoulders. Her symptoms resolved during the day on its own without any intervention. Pt. did not need to seek care at the hospital or with a provider. Reaction was self-reported on 2/10/21.

I had on-and-off insomnia starting around 10pm. I woke up every thirty minutes on the minute with a feeling like there was a fifty pound vest on my body. At 3:30, I felt nauseous. I walked from my bedroom to downstairs to the kitchen. My knees buckled several times en route. When I ate one bite of a protein bar, my nausea increased tenfold. I ask drank water at the time. I walked back upstairs to my room to sleep where remained awake until ~five am. I slept from ~five am until approximately 8:10am. I felt faint as I walked into the bathroom where I felt my faintness increase by the second. My knees buckled and I passed out on the bathroom floor tile for ~five - ten seconds. I payed there for a few minutes until I felt stable to stand. This morning, 45 hours after the injection and 22 hours after blacking out, I felt a goose egg on the back of my head. It has hurt all day at a level 4/10 on the pain scale.

Moderna COVID-19 Vaccine Injection site has become an itchy, red rash that has spread in a weird pattern across my upper arm Lymph nodes in that same arm are in quite a bit of pain to the touch and during movement The most sensitive area to the touch is also the most red Joint pain (knees)

January 28: Soreness in right arm January 29: Soreness in right arm, fatigue February 4: Noticed soreness under right armpit/above right breast February 5: Continued soreness in same location. Upon closer inspection, a lump slightly smaller in diameter than a baseball was visible in the area of soreness (underneath right armpit). The lump was noticeable by touch as well, but did not feel hard. It felt swollen but still fleshy. February 12: The soreness from the lump has subsided, but the lump is still present. The lump feels slightly smaller in size.

More sensitive skin: Had mild localized reaction to adhesive (redness, itching/burning, small bumps) that resolved in about 10 minutes after removing adhesive. Skin on legs formed large welts after scratching. Small spots of blood noted. This has never been an issue before vaccine. Showering/ shaving caused no issues.

Shingles outbreak on my face and in my eye. Flu like symptoms for 2 days after 2nd shot and then tingling/itching on my face day 3. Day 4 small bumps. Day 5 painful rash and swollen face. Day 6 and currently painful rash all over face, eye is swollen shut and shingles are now appearing on back and one blister on stomach. Everything is on the right side.

Multiple swollen lymph nodes in left neck/collar bone. One lymph node noticed at 7pm on 02/16. On the morning of 02/17 there were 3 and the original had grown in size. Original swollen lymph node is red and uncomfortable.

Right arm pain, redness, swelling, and itching with heat to touch; Headache; Muscle aches; Fatigue; Chills and Fever

Redness with moderate pain and mild swelling beginning at injection site and spread distally/down arm. Began small in size but currently approx. 3" x 6". Started 2 days after receiving second dose. I had no issue with the first dose.

Pt reported on 02/25/2021 at 12:45 pm stating her left hand was swollen. The shot was administered on her left arm. She stated she has a rash of goose bumps are red on both arms that are itchy off and on. Her entire arm is sore. We advised pt to contact her primary care physician and to keep us updated. We also told her it may subside with time.

Systemic: Allergic: Difficulty Breathing-Mild, Systemic: Allergic: Swelling of Face / Eyes / Mouth / Tongue-Mild, Systemic: taste of blood rising from throat-Mild, Additional Details: Pt has wisdom tooth infection and is taking Amoxicillin, anaphalactic reaction to MSG 6 years ago (we were informed of this after administration), pt stayed for 30 minutes after the shot was administered.\r\n

Delayed skin reaction about 1 week after the vaccination - it looks like a rash that covers approximately half of the upper arm, local to the injection site. The injected arm was sore around the deltoid area and the left armpit lymph node was tender, but was not visibly swollen.

I received my first dose of covid vaccine on 02/26/21 at Hospital. I felt completely fine the following day just minor soreness which I expected. On 03/07/21, exactly 10 days post my vaccine I developed hives/welts on both hands, both elbows , both knees, and toes that were elevated. I also developed some minor swelling but no fever, no pain just los of itchiness. I was given a vaccine of Medrol to calm down the sxs and seem to be doing okay.

Nauseous, dizzy, my arm doubled in size and is incredibly tender/painful, my head hurts, things smell like blood, and my throat hurts.

Swelling of lymph nodes in the neck area, on either side of the "adams apple" area. Injection site is hard, red and hot to the touch with tenderness. Do not recall it being there prior to 3/12.

The day following the second dose of the vaccine, I felt sick. Chills, sweats, aches, but no fever. Then the following day I felt better but had a annoying, constant headache all day. Then when showering I found a tender lump in my right armpit (same side as my vaccine). I?m pretty sure this is a swollen lymph node, and thought I should report it since I don?t have a spleen and I developed it pretty soon after the vaccine.

Arm swollen, +induration, unable to move freely. Denies fever, skin breakdown. Used Tylenol, Motrin with minimal relief

My arm was swollen for a couple days after (which I expected) receiving the vaccine. Then on saturday night after dinner and dessert (all things I've eaten recently so nothing new) I began swelling in my lips and under my right eye. I took 6 doses of off-brand benadryl and it would only decrease the swelling by very small increments. My breathing was alright, but to this day as of 03/22/2021 my lips are still slightly puffy.

One week after the first dose I experienced angioedema and lip swelling with blisters that lasted 3 weeks and didn?t resolve until March 4th. On March 6th I received the second dose completely healed with no symptoms and two days later I experienced tingling itching blisters and swelling that is currently still ongoing as of 3/23/2021.

Moderna COVID- 19 Vaccine EUA Patient received vaccine on 3/17/21 around 415 pm. Stayed for 15 min observation. In the evening went home and noticed swelling on the left side of her face along with a sensation change. Patient reached out via email. Encouraged pt to try icing facial area and take some ibuprofen. On 3/18/21 a follow up was provided, patient stated that the swelling went away, but the sensation on the left side of her face was still different. No other symptoms present. On 3/23/21 additional email communication with the patient was provided. Pt stated all facial reactions resolved, but she now noticed a lump in the groin area which she is seeing a PCP on 3/24/21.

a large, tender welt appeared at the injection site of my vaccine the day of receiving it. all of my other side effects have subsided but this one. it?s been two days and there?s still a large, red bump that is sensitive to the touch.

Fever of 100.4 degrees F., Chills, Muscle Pain, whole body Body Aches, Tiredness, Swollen Lymph Nodes on Left Armpit, Excessive Muscle pain & Body ache on Lower portion of Neck, Left Shoulder, Entirety of Left Arm (including upper arm, lower arm, wrist, upper hand & palm, and fingers).

4hrs post shot - sore arm with increasing soreness throughout day. 10 hrs post shot - fever, chills, fatigue, joint pain, back pain, overall flu like symptoms. continued for 36 hrs post shot, managed with acetaminophen 1g q6hrs. 48 hrs post shot - ONLY Left cheek edema, erythema, skin induration on affected area, hot, mild (2/10) pain; no other clinical signs of allergic reaction. Improved after 20 mg zyrtec + 40 mg IM Kenalog. Diagnosed with an allergic reaction, prescribed 6 day course or tapered dosing prednisone. 60 hrs post shot - Left cheek still swollen with involvement of suborbital zone, significantly improved from previous day, very mild erythema, mildly warm to touch, mild (2/10) pain. continued treatment occurring upon submission for this report. Patient has pictures of hourly progression of lesions.

-15 hours after the vaccine I had extreme chills, sweating, fever and myalgias until 6pm the next day. (symptoms lasted about 14 hours from 4am to 6pm). took 500mg of acetaminophen at 6pm the day of vaccination, 8am and 8pm the next day. -Cold sore occured 3 days after. went to urgent care and was given 2 valacyclovir 2000mg BID PO.

I woke up and my arm was really swollen with a red ring around the injection site and really hot. I also generally felt sick. I waited until the next day to see the doctor. He examined my arm and said the reaction was so delayed that it concerned him. He put me on a steroid and antibiotic in case there was infection. He told me to contact an allergist, who said it was too soon to get tested to see if I was allergic to the vaccine since they don't have a test for it. So, my doctor just told me to continue the meds. He also advised me to not get the 2nd dose and I haven't. I still have random shots of pain at the injection site.

Patient is a 24 year old female who has completed a 1 hour-minute observation period with the following signs and symptoms of an adverse reaction: swelling of the lips, tongue or face. Itchiness of throat Moderna COVID-19 vaccine# 1 in series administered. o Action(s) taken: Other - benadryl o 930: pt reported swelling of face (lips and cheeks) and itchiness of throat o Pt reported no problems of breathing or swelling in throat o 940 : benadryl given to patient pt vitals 125/75 SpO2 100 pulse 74 and RR 18 o 1008: DOD contacted agreed with benadryl administration plus video assessment of patient initiated at 1020 o 1020 DOD okayed discharge after 1 hour of observation pt was also sent prescription for steroid and antihistamine o 1055: last set of vitals 110/68 SpO2 100 RR 18 o 1100 pt Discharged, pt stated she felt okay. o Allergy to COVID-19 vaccine documented in Allergies activity: Yes o Patient advised to discuss second dose considerations with a clinician

Facial numbness and swelling entire right side of face and ear began at 11:50 after leaving the clinic. Symptoms not noted until in car. No difficulty breathing noted.

Approximately a week after receiving the first dose of the Moderna COVID-19 vaccine, I developed a kidney-bean sized lump, believed to be a swollen lymph node, in my left axilla, the same side where the vaccine was administered. The lump was mildly tender to palpation and gradually decreased in size over the next week until it was completely resolved. When I received my second dose of Moderna, the same swelling returned within one day post-vaccine, along with other lymph nodes on that side extending to my neck and jawline. These swellings took approximately five days to fully subside.

Red hard lump, warm to touch, & hurt if pressure on it. Was at another pharmacy to look for Benadryl, but pharmacist recommended Claritin. Marked boundaries & got bigger by the next day. Day 3 not as red but still a large area. Day 5 swelling down, but see circle where was swollen (bruise?)

After initial vaccination, I noticed a small rash near the injection site. I also had arm swelling and pain but it went away in about two days. However, one week after the injection I developed a rash on the side of my arm near the injection that is causing pain and swelling. The rash is continuing to grow.

Within a minute of receiving the vaccine, I got extremely light-headed, vision went almost totally black, body drenched in sweat. This passed after about 5 minutes. 30 minutes after receiving the vaccine, my throat and tongue started to swell. Went to the ER after benadryl wore off and the swelling returned. Am still managing the swelling of the throat and tongue 4 days later.

Swollen Lymph Node on collar bone. Pain from lump going up my neck and down my arm. Ongoing for the past 2 days. Still experiencing pain.

Mother called to report the Pt (her daughter) above developed fevers, lump in armpit (laterality not specified), muscles aches, chills, headaches. Lump has developed before in the distant past and was told by her doctor it was a lymph node and resolved on its own but lump developed within 24hrs of taking vaccine. Mother also with muscles aches, chills, headaches and fevers-much milder sxs.

My arm was visibly swollen , hot to the touch, itchy, burning, sore, and very uncomfortable. I am still having mild symptoms. I found relief in rubbing it with a roller ball.

Swelling of face and face felt warm to myself. However, via temperature gauge no fever was present. This lasted for approximately two hours. No medication was taken to combat the symptoms. Overall it was manageable, but I have never experienced something like that after a vaccine injection.

After getting the shot I felt feverish, chills, migraines/headaches, nauseated, swollen lymph nodes only under the armpit on the right side, tender arm, weaknesses in arm, cracking noises in shoulder and neck, neck aches, some tingling in arm

On 4/10/2021 the evening of her vaccine she had fever, chills, headache, and fatigue. 6-7 days later she said her right arm started swelling, rash, itching and painful for about 6-7 days.

I got the vaccine on Monday and at 7:30 pm the same say, I felt a bit of a tingling feeling on my upper cheek area on my left side. the feeling went away and then it came back on Tuesday in the evening, the same side and feeling. Then on Wednesday, the lightly tingly feeling is now both sides. My upper cheek areas are slightly swollen as well. I can still function, but I am concerned about this side effect to the vaccine as it wasn't documented. Or if it's an allergic reaction.

The patient reported minor facial swelling that started sometime the evening after receiving her first dose, and resolved about 8 hours later.

Constant vertigo and dizziness, paresthesia in arms and legs that comes and goes. Tinnitus, brain fog, anxiety. All continuous starting 4/16/21 and unrelieved by meclizine, methylprednisolone dose pack, benadryl, sudafed, and flonase.

Swelling of arm, large red welt, painful to the touch and producing heat. Consistent fever and body aches for 48 hours

Body aches & muscular aches Developed a rash on the food - purplish and red bumps, swelling, skin drying out (looks similar to covid toes) and has progressively gotten worse

on monday i had chills for about one hour. i also have a swollen and sore arm but now (two days after vaccination) has decreased

Swelling of the right side of face / neck, extreme redness on right side of face and neck , hot to touch on red areas, very disoriented, dizziness, headache. Examined by doctor and give 2 Benadryl.

4/21/21: starting 5 mins after shot - chills in spine, headache, lightheadedness; rest of day - arm pain, fatigue, headache 4/22/21: unbearable arm pain, fever, fatigue, headache, chills, loss of breath 4/23/21: headache, fatigue, arm pain, chills 4/24/21: weakness, headache, fatigue, arm pain, swollen lymph nodes under left arm, chills 4/25/21: weakness, headache, fatigue, muscle twitches, swollen lymph nodes under left arm 4/26/21: fatigue, weakness, muscle aches, muscle twitches, chills, join pain, swollen lymph nodes under left arm 4/27/21: fatigue, weakness, muscle aches, muscle twitches, chills, join pain, swollen lymph nodes under left arm 4/28/21: fatigue, weakness, muscle aches, muscle twitches, chills, join pain, swollen lymph nodes under left arm 4/29/21: fatigue, weakness, muscle aches, muscle twitches, chills, join pain, swollen lymph nodes under left arm 4/30/21: fatigue, arm pain, all over muscle pain, warmth in dorsal surface of feet (feeling like they are on fire) 5/1/21: arm pain, all over muscle pain, ankle/joint pain, lymph nodes under both arms swollen, warmth/tingling on hands and feet (both plantar and dorsal surfaces), fingertips pain 5/2/21: arm pain (both), all over muscle pain, ankle/joint pain, lymph nodes under both arms swollen, warmth/tingling on hands and feet (both plantar and dorsal surfaces), fingertips pain, bottom of toes pain, upper back/neck tingling and warmth 5/3/21: arm pain (both), all over muscle pain, ankle/joint pain, lymph nodes under both arms swollen, warmth/tingling on hands and feet (both plantar and dorsal surfaces), fingertips pain, bottom of toes pain, upper back/neck tingling and warmth, pain/spasms in thighs and biceps 5/4/21: warmth/tingling/slight pain on hands and feet, muscle spasms/aches in thighs arms, quads, shoulders, upper back; lymph nodes underarm swollen, ankle/joint pain

That evening my arm swelled up and became very painful - not as much as the first vaccine. I had a hard time sleeping - nausea and headache throughout the night. 4/3 - extremely tired; felt like I couldn't get enough air (shortness of breath) body aches and muscles aches - over all lethargic. 4/4 - I was dizzy, short of breath . Those two symptoms lasted along with fatigue - which lasted for two days. I almost passed out that day - everything went black and I had to be assisted to the couch to recover from that. I used Tylenol for my symptoms when needed. I still have ongoing headaches - three weeks ago (about a week after I got the vaccine) - I noticed I was having ongoing headaches and I still have these. Pregnancy - 2nd pregnancy; 1st one was full term. Date of delivery expected - September 9, 2021.

Woke up at approximately 3am on 05/03/2021 with sore arm. Around 9am on 05/03/2021 noticed large and swollen red mark that was warm to touch. Went to urgent care on 05/04/2021 and was advised it was an allergic reaction to vaccine. On 05/05/2021 woke up to rash that has spread to full body, still have large swollen red bump on arm. Advised by urgent care this is another sign of an allergic reaction to vaccine.

Swollen lymphnode in the neck on the right side, throbbing pain, swollen lymphnode in the collarbone area, right side. And Tinnitus.

1. Appendicitis: developed after 5 days, still early with low white blood cell count, followed by laparascopic appendectomy 2. Arm rash and soreness developed after 6 days at the vaccination location (left arm), with redness at the arm and swelling and pain of the arm.

Excruciating pain, body aches, fever of 102, lasting for 5 days and a migraine with neck pain for 7 days. Swollen shoulder injection site turned red. Sore throat for 7 days with cough

I had a hives outbreak three nights in a row all over my body. I?ve never had that happen to me, I?ve never been allergic to anything except spring seasonal allergies that are mostly post nasal drip and dry eyes. It got worse and worse over time and on the third night after eating Thai food which I always eat, my face started to swell and I went to the ER. I?m taking a steroid and Benadryl now.

The day after I was vaccinated, I woke up and noticed my arm had a red, swollen, and hot rash (it almost looked like an infection). It appears almost scaly and looks like the ?COVID arm? in the pictures presented on various websites. The area continues to be red and swollen on 5/21/2021 at 11 PM. The area causes my arm to feel pressure under my armpit since it is located on the outer area of my arm. I still continue to become chilled and hot/sweaty randomly through out the day as of 5/21/2021 as well.

She got her vaccine, after the 45 minutes her hands started swelling up, and her throat started tightening, about to close kind of feeling. She took some Benadryl and passed out for the rest of the day. Then about a week later the injection site started getting puffier and the whelp is now the size of her fist and is red and purple. She saw her PCP who is calling her in something stronger than Benadryl.

Arm felt sore and started a migraine like headache withing 30 mins Took a painkiller at the start of the next day....on the 3rd day, lymph nodes at the armpits were swollen and painful and got numerous boils on the trunk of my body and back, that were very red, sore, sensitive to touch, and very painful(looked up the net and it resembled shingles). This was the case for about 2 weeks, and then the pain started easing and scabs started forming on the boils, still have the scars

Fever up to 101 degrees. Severe headache and neck pain, hard to turn head and very light sensitive to light. Strong muscle and joint pain. Dizziness, shortness of breath, tightness in chest, elevated pulse, fatigue. Pain and a slight twitch in left arm, tender and swollen nodes in left armpit.

Patient reported arm was inflamed, warm to touch and the size of a golf ball. Patient also had fever. She was seen by her physician and given medication.

Large red swollen lump on left arm, about side of orange in width. High fever with severe shaking and very painful joints began Friday June 11th fever broke June 12th joint pain and arm swelling continues

24yo female with anovulatory vaginal bleeding and cramping x5 days which presented within 24 hours of receiving her 2nd dose Moderna COVID-19 vaccination on 06/09/2021. Patient describes her symptoms as if she is having a normal menstrual cycle. This patient uses Nexplanon for contraception successfully without a menstrual cycle for the past 2 years. Denies other urinary or vaginal symptoms, or possibility that she may be pregnant. Although there is high suspicion that this is a COVID-19 vaccine side effect, I will evaluate for abnormal anovulatory uterine bleeding with labs and follow-up with ulatrasound if her symptoms do not resolve with time. 24yo female with left sided supraclavicular lymphadenopathy presenting within 24hrs of her 1st and 2nd dose of the Moderna COVID-19 vaccine. Patient endorses waning symptoms after the first dose until she received the second dose at which point the lymph node came back. Physical exam remarkable for one 1x1cm left sided supraclavicular lymph node tender to palpation. Likely reactive lymphadenopathy. I will treat with watchful waiting given reactive lymphadenopathy to include supraclavicular lymphadenopathy is a known side effect of the Moderna COVID-19 vaccine, and that patient's young age and lack of risk factors. If persistent over several months I will re-evaluate the lymph node with imaging.

about 18 hours later my body ache fatigue and large hard bump on my armpit. Headaches and little fever. Went to the doctor for the armpit bump. The bump was on the same arm

Presented to ER with pleuritic chest pain and acute dyspnea. Her labs on admission were notable for WBC 23.5 with AEC 12.0 and IgE elevated at 1058 LV EF of 25%, Medium sized pericardial effusion with intermediate density concerning for pericarditis. Troponin 5000. Echocardiogram: small pericardial effusion and biventricular dysfunction with LV EF 25%, likely myopericarditis. CMR rest w/wo gadolinium showed global LV dysfunction and no evidence of T2 or LGE scar Patient started on 0.6 colchicine BID for treatment of suspected pericarditis given reports of periodic chest pains. CT chest w contrast: Dense consolidation in the RUL, RML with GGO throughout And patchy consolidation in the LLL with some microdularity with GGO. Significant mediastinal, subcarinal and hilar LN. Treatment with ceftriaxone and azithromycin

About a week after the first dose of COVID-19 Moderna vaccine, I developed an itchy rash around the area where I was injected (left arm). I took an antihistamine allergy pill (50mg) to help with the swelling. It's still red, flakey, and oddly shaped currently (06/26/2021). Symptom is mild thus far, but I wanted to note it.

Pt was in for her physical on 8/5/2020 w/ no noted abnormality of her neck/thyroid. She was then in on 2/15 after receiving her 1st and 2nd dose (2/3/21) of Moderna. She presented w/ concerns of a lump on her neck. Upon exam she stated to the provider that she and noticed tingling in her neck after the first injection. She then had labs done that day w/ our clinic, this was followed by a biopsy of the lump. She was then referred over to a healthcare facility for treatment/surgical intervention. To our knowledge she had a thyroidectomy done and is now following with the healthcare facility.

Headache for 48 hours and tingling and numbness in hands/fingers and toes. Fingers feel stiff and swollen.

At 4:42 shortness breath also became dizzy and nausea Sweating profusely that lasted about 20min. On the 19th had chest tightestness that radiated to arm. Hive and swollen lymph nodes swollen and visible.

We report a rapid onset of severe diabetes ketoacidosis (DKA) and transient profound insulin resistance in a 24-year-old female with type 1 diabetes after administration of the second dose of the COVID-19 vaccine. Patient required ICU admission

since 12/31/2020 experiencing Dizzy, Lightheaded, Chest tightness, nausea, Diarrhea , dry mouth, dry throat, chills, swollen lymph nodes, symptoms progressing

At 3am the next morning I woke up and felt nauseous. I felt like I had a fever and the aches. At 6 am I started throwing up and heaving for hours. Later in the day I took my temperature and had a fever of 101, my fever later broke after taking Tylenol and NyQuil. The next day, Saturday, my lymph node in the left armpit was so swollen I could not wear a shirt. My nausea continued but I no longer had a fever. My lymph node continued to be swollen until Monday. On Monday I woke up with a rash on the left side of my chest, small red dots and this resolved by the end of the day.

Received vaccine Tuesday 12/29 and adverse event occurred Tuesday 1/5. Adverse event being: began experiencing pain at the injection site, later noticing redness and a hardened bump at the injection site. While sleeping later in the night pain had travelled toward the clavicle area where a swollen lymph node was noticed not sure if related to the adverse event. Today, 1/6 pain, redness, and hardened bump are still there.

6 days after injection developed severe armpit pain and lymph node swelling. Day 7 woke up with hard, red, warm bump below site of injection with excruciating pain and limited arm movement. Seen by MD and started on antibiotics for cellulitis.

Received Vaccination Tuesday 12/29 and symptoms began Tuesday 1/5. 1/5 began experiencing pain at the injection site and later in the night noticed redness and a hardened bump at the site. While trying to sleep I noticed pain had traveled toward the clavicle area where a swollen lymph node was noticed not sure if related.

On 1/5/2021, a week after receiving the vaccine, a 2cmx3cm hive appeared at the injection site (rt deltoid). Raised, warm to touch, itchy. at time of reporting, approx 12 hrs later, there is minimal improvement. Took 1 benadryl at 2330 on 1/5. Mild discomfort and tingling throughout triceps on rt arm. I did not experience any side effects other than injection site soreness for 72 hrs after receiving the vaccine.

01/03/21 soreness in left armpit 01/04/21 to present swelling of lymph nodes and increased soreness, pain spreading to left breast and upper back 01/07/21 rash near left armpit

Cervical lymphadenopathy of only one lymph node (left-side), discovered 5 days post-vaccine. Localized rash discovered 8 days after vaccine. Stopped taking Zyrtec 4 days post-vaccine.

upper arm where i got the shot began to swell intensely. injection site was hot and painful to the touch. swelled up to about the size of a mandarin orange. swelling went down on day three, however a week and a half later i still have a red circle about the size of a US half dollar coin.

Symptoms began with arm soreness with minor swelling around the administration area around 6-7 pm. Chills began at 11 pm lasting for half an hour followed by a fever of 102f. The fever continued during the night of 1/5/21 and early morning of 1/6/21. Woke with a strong headache in the morning at 7 am. Headache caused dizziness and some loss of balance when walking. Had minor facial swelling with minor numbness around mouth and neck. The fever, headache, and swelling continued throughout the day of 1/6/21. The fever broke around 7 pm on 1/6/21. Nyquil and ibuprofen were taken for fever and headache. During the morning of 1/7/21, the fever and facial swelling had ended. The headache continued during the morning of 1/7/21 until midday. By the evening of 1/7/21, all symptoms had ceased.

(Written next day) Patient stated that shortly after receiving the vaccine approximately 30-60 min minutes later she started to feel swelling in her face as well as her lips. She took a photo of this and showed it to me today and well. The swelling around the eyes seemed minimal. Her lips were swollen. She also notes that she felt tired and had a mild shortness of breath where she felt more comfortable sitting up. She states these symptoms have somewhat improved, though she has been experiencing increasing nausea since yesterday and continues to feel that way. She states that she does not believe she is pregnant, she has an IUD. She also noticed some body aches yesterday, continuing this morning, but they seem to be improving. They do improve greatly with ibuprofen at home.

Approximately 3-4 hours after getting the vaccine she experienced every symptoms possible, hit her all at once. Felt like every part of her body was breaking and being stabbed. Severe pain. Fever, chills, abdominal pain, back and neck pain. Chest pain, felt like she was losing consciousness. Was in ED until next day Saturday discharged around 7 am. Had morphine, Benadryl and Toradol while in ED.

Fatigue and body aches 1/8/21 8:00 pm. Severe chills and body aches 1/8/20 11:00 pm continued for several hours. Muscle and body aches and fatigue continued until 1/10/21 7:00 am was gone. Swollen lymph nodes on neck (still experiencing this 1/12/21)

On Friday 1/7/2021 I noticed my arm was red and swollen. It also hurt and I was not able to lift it. I went to urgent care on Saturday on 1/8/2021 and they prescribed my antibiotics. Today 1/12 it has gotten worse. It?s still red and hot, but less swollen. It has began to itch and stings.

immediately upon vaccination, vaccinator noted flush to arm, redness on anterior surface which hadn't been red before; noted slight bleeding from site; brought to observation area; left and right arm both red; no itching, no breathing issues, not warm at first. Patient observed for ten minutes and then the area was becoming red, warm to touch and slightly raised, looking like hives. Patient given benedryl and continued observation for 20 more minutes. No changes, not worsening, let leave and advised to return if any spread or further problems. Noted to have no breathing, itching, palpitations, nausea or other side effects. Advised to not take the second vaccine.

Patient began having cramping of her upper extremities and subsequent swelling of her face and neck and also shortness of breath, chest pressure and flushed appearance. She denies any tongue or throat swelling. She is also complaining of bilateral arm pain. The initial reaction treatment was started in the conference room and then the patient was transferred to the emergency room. She continued to has arm and chest pain in the emergency room. She had muscle tension/rigidity in the upper extremity which caused significant pain. She also developed a nonspecific rash on the chest and abdomen that persisted for through out he hospital stay. Treatment was started with epinephrine 0.5 mg IM x2 and diphenhydramine 50 mg IM x1, prior to transfer to emergency room. In the emergency room treatment was dexamethasone 10mg IV x 1, famotidine 20mg IV x1, Ketorolac 30mg IV x 1, lorazepam, 1mg IV x 2, morphine 4mg IV x 2, 1000ml Saline Solution. As an inpatient the treatment included scheduled acetaminophen 500mg TID, as need morphine for pain after treatment with fentanyl, scheduled diphenhydramine 25mg IV q8 and compazine 5mg IV for nausea, cyclobenzapine 10mg as need for muscle spasms, dexamethasone as a scheduled dose started at 4 mg BID and tapered to 2 mg BID, Naproxen 500mg BID and Norco 7.5/325 as need for pain. with famotidine 20mg BID .

Vaccinated on 1/5, had normal side effects including soreness and swollen lymph nodes in axillary region of R arm. Soreness continued through 1/11 and worsened 1/11 at night. Woke up on 1/12 with red, itchy, raised rash which has since spread. Saw PCP 1/12 who determined it was cellulitis at the injection site, started on Keflex 4x daily for 10 days

Headache, fatigue, sore throat, swollen left axillary lymph nodes and swollen lymph nodes on the left side of the neck.

8 days after receiving the Moderna vaccine, I noticed a large and swollen red area on my arm where I was injected. It is not painful or itchy, just warm to the touch. Over night, the area got less red and less warm but the swollen area had gotten larger.

Vaccine Moderna 1/7 /21 That evening myalgias, arthralgias - following day same with temp 99.7 by the evening. AM 1/9 all of the above Sx's had resolved. PM of 1/9 noted intense itching of fingers and wrists - fingers appeared slightly swollen to her. Similar Sx's feet and ankles a few hours thereafter. Took Benadryl Hs and slept comfortably. 1/10 - awoke with urticaria back of legs - from knees to buttocks bilaterally. Hives resolved after 2 hours after Claritin. Another episode finger itching and swelling lasting 30 minutes. Resumption low grade temp last PM 99.7 - 100.4 max last night in evening transiently. Back down to 99.9 1-2 hours thereafter. + fatigue since immunization. Took Claritin this AM. No further hives.

Days 1-3 arm soreness and swelling Day 7: notice arm is still swollen near injection site Day 8 and 9: itchiness and redness near injection site, swelling is still there, area near injection site is very very warm to the touch

Nausea, vomiting, fever of 102 for 5 days, chills, body aches, joint pain. Local reaction on day 7, itchy, swelling, hard lump, bright red, roughly 8 ×10 cm. Kidney pain

I woke up on Sunday, January 17 at 7:30 AM and noticed my lymph nodes on both sides of my neck were swollen. The left side was more swollen than the right side. The swelling is closer to my clavicle then higher on my neck. I am having no pain with the swelling and I have no temperature above normal.

Site: Swelling at Injection Site-Mild, Systemic: lymph nodes swollen in left armpit and pain radiating to elbow; symptoms lasted 6 days

Site: Bruising at Injection Site-Mild, Site: Pain at Injection Site-Medium, Systemic: Nausea-Mild, Systemic: Swollen Lymph nodes in armpit-Medium; symptoms lasted 6 days

After receiving the vaccine 1/9 in my left arm, I had normal side effects of chills, body aches, and fatigue. On 1/14, I noticed the left supraclavicular lymph node was enlarged, no pain with palpitation. On 1/15 the underside of my left arm was itchy but no visible rash. On 1/16 the arm was still itchy and the lymph node was more enlarged. No neck or axillary nodes were enlarged. On 1/17 in the morning I woke up with a large red rash on my left deltoid. It was not itchy, but as the day went on was more red, raised, and warm. The node in my neck was causing some neck discomfort. I presented to Urgent Care and was treated for a local reaction. I was given a steroid cream to use on my arm and was told to take an OTC antihistamine. I have been using the cream for 2 days and so far the rash is resolving but is still visible. The node has not yet decreased in size.

woke w/ arm pain the following day which resolved, 12/28 arm pain, swollen, gland axillary/post neck, eval PCP; inc redness by 1/1/21, seen in ED, RX for cellulitis

Around 1 week after vaccine was administered, the site of the injection swelled up and was both painful and pruritic. The lymph node in the armpit of the arm that received the vaccination was also swollen, painful, and palpable. I also felt more fatigue than I normally do. Symptoms resolved within 2 days.

After a week, my arm started to itch and in a few hours it swelled up. The site was red, itchy, hot and hard to the touch. My arm swelled a bit on the day of the shot but it was small and went away after 2 days. But a week later it showed up and the swelling was bigger.

Moderna COVID-19 Vaccine EUA 48 hours of fever, chills, fatigue, aches, nausea. 48+ hours of arm pain, swelling, stiffness, and immobility. I still cannot lift my left arm past 90 degrees from my side. I can not reach across or behind my body with my left arm. I cannot lift any significant weight using my left shoulder.

Fever-t-103, facial swelling, tongue tingling. Started 1/16/21- next day after vaccination, treated with Benadryl. Seen in ER- given prednisone.

Patient received the Mederna Covid vaccine on 1/14/2021. On 1/19/2021 started with swelling to lymph nodes in the arm pit and collar bone. On 1/20/2021 started with redness and itching. 1/21/2021 Woke with redness swelling and hot to touch to the right arm.

Developed right axillary pain, fullness, and warmth starting Monday, January the 18th, 7 days after receiving the vaccine. The morning of January 19 experienced noticeable right arm swelling, decreased range of motion, and a 4x6cm area of erythema around the injection site. Significant general fatigue starting Monday the 18th. 2x2cm abdominal rash developed on Wednesday the 20th. Resolved right arm erythema and abdominal rash on January 21st. General Fatigue and right arm discomfort are improved but still remain. Was prescribed Methylprednisolone 4 mg dose pack and cephalexin 500 mg TID on Tuesday the 19th. Did not start medical treatment due to quick improvement of symptoms.

About 30 min after the vaccination I felt dizzy. It felt almost like I had gotten up too quickly and felt dizzy, that kind of dizziness. Lots of soreness on the injection site the day of the vaccination and also going down the arm if I tried to lift my arm it was painful, everything else was fine until 4:30PM when I started feeling chills and feverish. Around 9PM the cold chills were so awful I started crying because it was so uncomfortable. I took some Tylenol and it knocked me out. I felt cold and hot during the night. About 7AM the next morning I had hives, on my chest, arms and legs (red itchy, swollen) the chills have gone away in the morning. I took an Allegra around 8AM and it did work after 30 min to an hour. Then I went to see my allergist around 11AM and the itchiness and redness had gone down a lot but the itchiness was still there. The allergist told me to take some more Allegra that day and it ended up working.

Immediately itchy, later on become swollen and hot to the touch, now has doubled in size, raised and reading 100 on thermometer. Left arm feels heavy and numb like its been slept on all night. Taken Tylenol, allergy medicine, plenty of water and only getting larger

My face became numb and tingly as if I was at the dentist and got a shot to numb my gums and it was wearing off . My whole face felt this way. For at least about 1-2 hours. Additionally at about 9:00pm to the next morning 1/20/21 I began to get pain in my armpit I examined using my fingers and felt it sesintive to touch and consulted with a physician who said my lymph nodes must be swollen as a response.

I started to notice on Tuesday, January 19th, that there was a red bump on my arm. It looked more like a mosquito bite to me and was not bigger than a quarter. It didn?t feel itchy but I thought nothing of it. I noticed when I got home it was twice as big but I still felt no pain. It appeared that my arm was also swollen. The following day on Wednesday, it has grown in size again covering my arm, maybe the size of four quarters. Throughout the day it felt a bit hot, especially when I touched it. It did not feel itchy and I didn?t feel any pain. I felt a bit tired this day so I?m not sure if it was because of it. The redness has gone down today (Friday, January 22nd) however the mark is still big and in the shape of a square now. The outer part of the mark is more red and raised up, like it has a red border.

Fever, chills, body aches (back), and one enlarged supraclavicular lymph node on same side of vaccine appeared 6 days after vaccination and is still present 9 days later. Initially painful. Pain subsided after 24 hours. Painful left armpit night after vaccine and morning after.

My left arm is swollen and red. Additionally, my left lymph node in my armpit has been swollen and in pain for 3 days now. I have been icing the injection sight and taking ibuprofen

Cold sore 1 days following vaccine, mild swelling of lymph nodes on jaw and neck non-tender. severe lymphadenopathy of neck, tender beginning on 1/20/21. General fatigue, feverish, and sore throat. Antibiotics started on 1/23/21. Decrease tenderness of lymph nodes on 1/24/21

30 minutes after itching tongue- self resolved 8 days later super edematous arm with a 6 inch weld that was approximately 1 inch raised off the arm- got bigger over 5 days then went away- Arm would not fit in shirt sleeve

Flu like body aches. Arm was swollen, painful and red. Took motrin which helped with pain but not aches.

Red rash on left arm appeared around 1/24/2021 and has became larger as of 1/27/2021. Rash is not painful. Lymph node in left armpit is enlarged and painful since onset of rash and persists as of 1/27/2021. Rash and lymph node tenderness only started around 1/24/2021. Only immediate event after vaccine on 1/16/2021 was typical vaccine muscle pain that went away after 3 days.

Red, hot, tingly spot appeared 2 days after injection. Went away after a couple of days and then re-appeared Exactly a week after injection as a larger, puffy, red spot. Has spread larger every day. Hot to the touch and causes arm to be weak and tender

Had shot 1-19-2021 with no reaction. On 1-27-2021 woke up with red, warm, tight arm. With arm itchy and swelling and knot size of 4" x 2"

The day after the vaccine I started spotting and my back started getting numbness down my legs. I kept moving my legs because I was afraid I was going to lose feeling in them. I got an X-ray and it showed there is nothing wrong with my back and I concluded it has to be from the vaccine because it has resolved for the most part after 3 weeks. I was extremely fatigued for 3 days and my left cervical and right axillary lymph nodes were swollen. I had a huge welt at the injection site for 2 weeks and now there?s still a bruise there. I am afraid to get my second vaccine because I don?t want to lose feeling in my legs. I need guidance from someone who knows a lot about this vaccine because no one is able to give me guidance.

01/27/2021- 01/28/2021 Wheezing, hives, swelling of injection site, fingers, underneath eyes to chin, including cheeks; and vomiting. 01/29/2021 @0817am Patient arrived to work c/o redness and sweeling at site of injection. (Left Deltoid.) Also hives on torso and rash down legs. Also experiencing chest discomfort, (described as throbbing and achy). Took Benadryl this morning on way to work. Denies shortness of breath or weakness, denies blurry vision. (Day 2 after Vaccine)

On the day of vaccine, after 6hours, Swelling and painful on left arm and Shot area temperature is higher than other body part. Got fever at night, last few hours , back to normal temperature in the morning. Today is the second day, Left arm is still pain and feel pain when move around or being touched.

High fever but was able to bring down to a low fever in an hour with ibuprofen, dizziness and confusion the first day afterword. Localized swelling to the size of a soft ball; red, hard, and hot to the touch

Anaphylactic reaction, with tachycardia, hypertension, throat swelling/dyspnea, facial swelling, and diffuse hives.

Day after vaccine, large swelling around area with redness. Hot and tender to touch. Continued for approximately 3-4 days with redness spreading further. Lymph nodes in general area of vaccination swelled. Discoloration around injection site once redness and swelling went away. About a week after initial symptoms injection site became red and itchy, lasted for three days. Discoloration still there, now muscles around injection site feel fatigued with movement.

High fever but was able to bring down to a low fever in an hour with ibuprofen, dizziness and confusion the first day afterword. Localized swelling to the size of a soft ball; red, hard, and hot to the touch.

Around approximately 8:30 started having rigors, muscle aches, headache, and chills. Then at approximately 12:00 am worsening symptoms of rigors, muscle aches, headache, and chills. New onset of nausea, vomiting, diarrhea, sweating, fever of 103 degrees fahrenheit, SOB, racing heart, and fatigue. Multiple episodes of vomiting and diarrhea from 12:00 am until 4:30 am. Unable to tolerate anything by mouth. Mouth dry, lips dry, and limited urine output. At approximately 5:00 am client admitted to ER. Client received 2 liter's of fluid and IV Reglan. Labs draw and elevated WBC noted but all other labs within normal limits. Blood glucose elevated at 237. Client administered insulin via insulin pump per physician request. Client has history of insulin dependent type one diabetes. Client discharged to home at approximately 8:00 am. Prescription given for oral Reglan and to return to work after 01/24/2021.

I received the first part of the Moderna vaccine 1/9/21 in my left arm. On Thursday 1/14 I noticed an enlarged supraclavicular lymph node on the left side. On Friday 1/15 I had some itching on my arm but no visible rash. On Sunday 1/17 there was a large visible rash localized to my left deltoid. The lymph node was causing some neck discomfort as well. I presented to the Urgent Care as was given steroid cream to apply and I have also been instructed to take an OTC antihistamine.

Received vaccine at 8:58 am. Around 3 pm started with fatigue. Fell asleep from 3 pm - 10:30 pm. Woke up with a 102.1 fever. Had severe headache. Fever and headache lasted until Monday, 02/01/2021. On Tuesday, 02/02/2021 I woke up with my lymph nodes in R armpit/chest swollen and painful. Still not resolved.

Itchy, warm rash. Very swollen and sometimes painful lymph nodes under armpit. Same side as injection.

Beginning 3p on 2/1: nausea, pain throughout entire left arm By 10p on 2/1: nausea, pain throughout entire left arm, painful lymph nodes under left arm, dizziness, nausea, joint pain, muscle aches, hot flashes, chills, loss of appetite/vomiting, headache, fatigue Symptoms persisted at an intense level for approximately 3 days

injection site pain, on 1/29/2021 employee experienced tiredness, muscle pain, chills, joint pain, etc. Employee also has swelling of the face, and fast heartbeat

I received the second dose of the Moderna COVID Vaccine 3 FEB 21. Within 2-3 hours I was incredibly tired. I was hit with intense nausea and vomiting that has been persistent since the night of 3 FEB. I can?t keep much down. 4 Feb I had a fever of 102.3 starting around 4am, I brought it down with a 600 Mg dose of Ibuprofen but it came back off and on throughout the day alongside sweats and chills. All of my lymph nodes were swollen and my entire body hurt. I was unable to sleep last night 4feb/5feb due to muscle pain. As of today I feel a little better and am without a fever, but I am still incredibly nauseous and have developed a sore throat.

Swollen about the size of an egg at injection site, heat, redness, tenderness. Arm became swollen after about 18 hours and has remained pink, swollen to the size of an egg, and warm since.

About one hour after injection: I had a burning sensation in chest and throat and swelling feeling; I felt a bit of throat swelling. I got very tired about two hours after and arm pain. The throat and chest burning/swelling sensation slowly dissipated within an hour or so. Around 4 pm, I got pretty bad heartburn - very rare for me. Very distinct heartburn feeling; uncomfortable and that lasted about an hour. I had body aches at night time before I went to sleep. The next day I woke up feeling fine. One week later, I had another response. I had my throat start to swell again and this time it was worse. I had itchiness on my arm on the 6th night but I didn't really notice it but that seventh day, I realized there was a rash and itchiness in my arm. I had broken out all over my face - tiny pimples had broken out. I contacted an allergist - I was getting scared about my throat. The allergist said they had seen this a few times after the vaccine - told me to take Pepcid and Benadryl. I did that and that took away the feeling in my throat and made me feel better. I continued both those OT meds for 3 or 4 days. On fourth day, I started getting throat swelling again and the rash on my chest - these were more mild symptoms than earlier but I called the allergist and he advised I take Pepcid and and Zyrtec instead of Benadryl for three or four more days. That helped. After that I seemed to be good. On 13th of January - shortness of breath and chest pain. I spoke with Dr and got a COVID test. I had my inhaler at that point (I haven't had asthma in years and I had to take the inhaler a couple of different times throughout this time). 14th of January - Chest pain. 22nd of January - Chest Monday. On Monday, the 25th, I started taking - in advance of my second dose of Moderna- Zyrtec and Pepcid twice a day on the 25th; twice a day on the 26th - on morning of 26th, I took Zyrtec again an hour before the second dose of the Moderna vaccine. I got the 2nd dose on the 26th. (The days that I had chest pain - I took ibuprofen and that seemed to help.)

8hrs after vaccination - arm swelling and soreness After 15 hours-nausea and headache, low grade fever, chills After 24 hours was not able to stand for more than 3 minutes without feeling extremely lightheaded and needed to lie down. Mild headache, nausea, fatigue, body ache and arm stillness were present during this timeThis lasted about 4hrs. After 30 hours still arm soreness and swelling and all other symptoms are very mild

Mild chills and joint pain started in the middle of the night (about 12 hours after second dose). Treated with ibuprofen and resolved about 10 hours after onset. Swelling and lump the size of a quarter at injection site noticed about 10 hours after injection. The next morning size increased to about 4 inches in diameter, skin was hard, hot, and painful to touch. Left armpit is also swollen and mildly painful. Now, (3 days after injection) swelling still present. Still hot and hard to the touch and size remains the same. Pain and redness mostly resolved. Now starting to itch.

Red blotches/blistering and slight swelling on 1st and 2nd toe of right foot (looks similar to "Covid toes"). Started as swelling of 2nd toe with some pain on Tuesday, February 2nd. Progressed to red blistering on 1st and 2nd toe, the swelling subsided somewhat by today (February 8th). Slight pain remains through today (Feb. 8th). No prescribed treatment. Took Advil periodically for swelling, tried to keep feet warm.

rash and swelling at injection site then large hard welt occurred, 1 week later redness occurred and lymph nodes under arm swelled and are still there. Both sites are painful.

Fever lasting 36 hours, highest of 102.5 degrees. fatigue starting at 12pm after receiving shot at 9am. Soreness to touch, redness and slight itching throughout left upper arm also starting around 12pm day of the shot with increasing redness since. Redness is irregular and not in single spot, moving throughout upper arm. Armpit pain and swollen lymph nodes. After first shot had redness in an oval shape at injection site along with swollen lymph nodes in left armpit

Patient called in to the nursing supervisor at approx 02:40. She was not on the schedule but was stating that she was having a reaction to the Covid vaccination she recieved the evening before. It was noted that while she was talking with the supervisors her speech was thick and she stated that her tongue felt swollen and larger than normal. She also stated that her significant other told her she sounded different too. She stated she had redness from her earlobe to her wrist on her R side, which is where she got the vaccination. She got it at appx 18:30 she had said, and when she got it during the observation period she was noted to have a very red and hot arm, but overall she felt fine. She also stated that she has had a covid infection recently. She stated she took 1 childrens dose of benadryl but was worried because she is breastfeeding. We advised her to call 911. *** 1000am- #2 vaccine given on 02/9/21 @ 610pm. felt ok for the first 15 minutes during the waiting period; the site was examined by the Medical assistant & was very hot to touch & red about the size of a baseball. She was dismissed from the vaccine clinic. She went home and around 7:30 pm felt swelling in her tongue & mouth. She disregarded this symptom and went to bed, she awoke @ 2:30 am and felt her tongue was more swollen & then called the nursing supervisor. Patient took Benadryl 50 mg at 0230am. NO response from the Benadryl. Went to the ER @ 0400 called 911, B/P was 155/88 & O2 sat 89%. She opted to go to the ER by private vehicle. Went to ER. She was give IV fluids, Benadryl & monitoring. Discharged from ER this am. Hx of allergy of bee stings. Stated this reaction was the same as a bee sting reaction. Discharged from the ER to take tylenol & Benadryl & monitor. During this call she stated that her tongue is still a little swollen, speech is clear, Denied SOB. Temp 99.8 during this call. Lymph nodes in her in neck are swollen- she said there is 1 area near her right collar bone the size of a golf ball. Currently nauseated, denied chest pain. She does not qualify for testing since she had Covid on 01/8/21. A VAERS report will be submitted today & I will add that ID # to this documentation. :PLAN Clear to work; yet verifying with physician if any additional instructions.

I woke up around 4AM with fever, cold chills, nausea, and body aches. I had the body aches and chills for two days and then I was okay. My arm was very swollen, red, and painful. I also had a reaction to my first vaccine lot #011J20A where 8 days after the dose my arm had a red rash, very swollen, hot to the touch, and painful. This reaction took about 5 days to go away.

Moderna COVID-19 Vaccine EUA Three days following the injection I had most of the symptoms. The injection site was hot, hard and quite painful (I couldn't sleep on that side of my body for three nights). I felt generally unwell and achy. After about three days all of my symptoms went down and most of them were gone except for I could still feel a small amount of swelling under the skin that continued to go down. On Tuesday Feb 10, almost a week out I started to experience an itching feeling that increased throughout the day to a deep itch that feels like it goes down to my bone. The injection site has become red, hot and hard again and the lymph node in my left armpit is extremely painful and swollen. I feel dizzy and nauseous.

After 3-4 hours, patient experienced pain in left arm at injection site that increased throughout the day and into the evening. The arm became swollen in the evening hours. The patient experienced fatigue during evening hours. The next morning, 24 hours after receiving vaccine, patient experienced fatigue, pain and swelling in arm at injection site and patient ran a low grade fever that lasted until 4 pm that day.

I had headaches 3 ours after the vaccine along with body aches. The next day symptoms worsened My face swell up along with my body due to the vaccine. I got treated where I work here at medical group by one of the FNP she gave me a Depo medrol shot for the allergic reaction I had.

Starting Thursday night (2/18/2021) my arm became extremely itchy. When I woke up this morning (2/19/2021) my arm was swollen, red and stilly itchy at the injection site. This is a week after the shot was given.

Day 6, woke up with swollen armpit/lymph node and pain on left side. Day 8, lump at injection sight, including red, itchy, and warm to touch

12/28 Vaccination 1/4 6-7 days lays, adenopathy, cervical lymph node swelling. HA relieved by Tylenol. Mild arm pain, similar flu shot. 48 hours later cleared up after taking Benadryl. Saw occupational health. Prescribed Claritin, hydrocortisone cream.

On Monday February 22, the lymph nodes in my right arm pit started to swell but not too much and is one of the side effects. Wednesday February 24 the lymph nodes in my right arm pit started to get sore and you could see lumps under my skin. Thursday February 25th I woke up with bad pinching pain in my right arm pit and the lymph nodes are about twice the size that they were yesterday and more painful. One feels bigger than pea sized.

Red, swollen arm with itchy rash below injection site, started about 8 days after receiving first dose of vaccine (?covid arm?)

1 week and 1 day later it was noted while showering that there was a 2 in red raised mark surrounding the injection site that was itchy. 2 days prior to red mark appearing I was experiencing extreme headaches, fatigue, sore throat, and swollen lymph nodes. At this time on 2/28/2021, I still have the raised red mark on my area but it has lightened and it is still itching. My lymph nodes are still swollen and a headache is still present as well as fatigue but the sore throat has mostly resolved.

Within one month after vaccination, developed joint pain, joint stiffness, joint swelling in bilateral finger joints. Had labs, xrays and assessment completed. New finding and diagnosis of rheumatoid arthritis

pt stated that 10 minutes after receiving the covid vax her throat started closing so she went to the ER. She had hives, chest tightness, and unable to breath. They injected epi-pen and administered steroids, Pepcid and Benadryl. She was released to go home after 5 hours. The next day she had really bad sternum chest pain, back pain, neck pain and fatigue so she went back to the ER. They did chest XRAY that came back clear, did an EKG w/ normal results, and blood work w/ high white blood count. New RX for Naproxen 500mg, lidocaine patches, Zofran and has an EPI pen on order. Pt states since leaving the ER she still has fatigue, pain in neck, arm, back, and now in the face. She states her face is numb and has bad pain and blurred vision in both eyes, more so on the right side. The ER told her to come back if she needed to FU.

Exhaustion, insomnia, fever, swollen lymph node in right underarm. Painful to the tough and without. Grew to size of a golf ball.

My arm started hurting very bad after about 2-3 hours. At the 12 hour mark from my vaccine (11:30PM), I started to have chills, a fever, and feel nauseous. Around 1 AM I started to vomit and this occurred for about 15 minutes, and then repeated again about an hour later. By the morning of the day after I was no longer vomiting or had chills but still had a fever. The most prominent symptoms on the day after my vaccine were extreme body aches and horrible joint pain. My hands and feet felt swollen and stiff. I had terrible pains and aches in my whole entire body. I was also very tired and still had a low grade fever. On the second day after the vaccine I had bad chest and neck pain and started to have a mild cough. By the third day after the vaccine, the chest pain was gone but still had bad neck pain and a headache that radiated through my skull.

The day after I received my vaccine, I had extreme fatigue, chills, body aches, and felt feverish. I also had severely painful swollen axillary lymph nodes on the same side that I received my injection. I was not able to work or do any of my daily activities for almost three days. Then on day 7 after receiving my first vaccine dose, I developed a itchy, painful, red rash and hives surrounding the injection site (about a two to three inch radius around the injection site. I also got hives and red itchy painful skin on my face. I went to an urgent care and was prescribed prednisone and a week of pepside and zyrtec. After a week I stopped taking the allergy meds and then the hives came back, so I kept taking the allergy meds until my second vaccine dose.

Fever 100.8 at 3am and 6am Took tylenol at 6am. Chills and sweats from 3-6am. Fever was down to 99.8 at Noon. Intense upper back pain and pain around ribs at 1:00pm. Took tylenol at 2pm and heating pad on back. Did not help. Called clinic's vaccine hotline around 2:45 describing my pain and asking if it was normal. Nurse told me to go to the ER. Admitted to ER around 4:00. They found chest wall and axilla: Multiple enlarged left axillary lymph nodes with adjacent stranding.

Red mark approximately 2.5in below the injection site (mark was small, approximately 1.5in x .5in and bright red ) Outbreak of cold sores on lip. One sore appeared the morning after the vaccine and quickly spread to a min of 20 sores clustered across the bottom lip. I have a history of getting cold sores(either from exposure, stress, illness/immune system compromise, or sunburn), however I have never had an outbreak of cold sores anywhere near this extreme.

16 days post vaccination I broke out into truck hives with occasional spot of arms and legs. Hives stayed for 4 days start to finish and were unaffected by benedryl and other antihistamine drugs. Cortisone creams also had no effect. Hives were raised but not red and did not bother me other than visually.

Beginning 3/3/21 my left arm began to hurt and my fingers became numb (as if my arm was asleep). I noticed swelling in my arm and began taking Ibuprofen. Sometimes my arm would begin to "wake up" and my whole are would tingle. On 3/7/2021 I developed a red area around the injection site and my arm swelling was more pronounced. My arm also feels hot somtimes. I have continued to take Ibuprofen and place ice on my arm in the evening. I continue to have the swelling, hot arm, red patch, and pain in my arm as of today. The "numb" feeling is something that comes and goes.

?Moderna arm? reaction on right arm. Swollen, lump under arm that started small but grew bigger. Currently a little smaller than a golfball but has grown baseball sized when scratched or touched. It?s hot to the touch and has a red rash about the size of an orange. It?s itchy and burns

-pounding headache lasting 8 days -swelling of the face, eyes, neck, and lymph-nodes in neck for 9+ days (ongoing) -Swelling of the armpit and pain in the lymph-node under the armpit for 5 days

several cold sores developed on Sunday afternoon, worst outbreak she's ever had. Took Acyclovir with initial tingling of lips. She usually doesn't get cold sore when takes Acyclovir at first sign. Also had headache for 1 day and fatigue x 3 days

Covid Arm, large swollen lesion that is hot to the touch and raised and red. Large circle around injection site appeared after ?bruise? appeared 7 days after vaccine. Still present.

Fever 102 Chills Shaking Swollen lymph node in arm pit Headache Body soreness Pain and swelling at injection site Nausea Vomiting Diarrhea Extreme thirst Fatigue Overall discomfort Sore throat 10pm day of injection to current 4pm next day

Redness, swelling, and tenderness increased from about 0.5inches 24 hours after injection to about 3 inches in diameter two days after injection.

Around 6:00 pm on the day of vaccination I started to feel very fatigued and developed body aches - this felt similar to the beginning of developing Covid-19 symptoms. (I had Covid-19 back in November of 2020) Around 8:00 pm I had developed some head congestion and swollen lymph nodes along with some throat pain and sinus congestion - again feeling very similar to Covid-19 symptoms. Around 10:00 pm as I was heading to bed the symptoms became a lot worse, I had pretty intense body aches and started to experience chills as well as a slight fever (around 99.5 in F). At this time the symptoms felt similar to how I had felt during the worst of my previous Covid-19 symptoms, very weak and achy, headache was very bad, and felt very uncomfortable overall. Around 2:00 am on March 13 I woke up with a fever of 101.8. The previous symptoms had also gotten worse, I was having a hard time getting out of bed because things were very uncomfortable, I drank a lot of water and took some ibuprofen to combat the fever, about an hour after this the fever had come down to about 99.9 and I was able to fall asleep, but before taking the medication I couldn't have fallen asleep because of the discomfort of the aches, chills, and fever. Throughout the following day I was unable to complete many of my day to day activities without taking a daytime cold and flu medication. With the medication I still felt sick but was able to walk around and complete some simple household chores, this carried through into the evening, when the medication wore off the chills and aches and headache were much worse and I still had a fever around 99-100. That night I was able to sleep with the cold and flu medication taken right before bed. Upon waking up the next morning (March 14) I still had some congestion, headache, and general discomfort but the worst of the aches were gone and I no longer had a fever, these symptoms continued to diminish throughout the day. On March 15 and March 16th I have had a slight lingering congestion headache, this also feels really similar to the lingering headache I had upon recovering from Covid-19. It is not debilitating and is continuing to improve. Otherwise I am feeling healthy again and have been able to complete my usual activities and even exercise. Overall the symptoms felt like a couple days of having Covid-19 again, but recovery was much faster, and it was definitely worth receiving that first dose of the vaccine and getting started with the process of doing my part to reduce community spread.

-Soreness in the arm (Day 1) -Fatigue: the evening of day 1-day 3 -headache: day 2-3 -Muscle aches: day 2 -Chills: day 2 -Lymph node pain/swelling in armpit on same side vaccine given: day 7-present

March 18, 2021 I noticed my arm was itchy but only had a few small bumps. Later that same day around 9:00pm I noticed a uncolored 2 1/2 inch in diameter welt on my arm and it was very very itchy. I took Benadryl and went to bed. March 19, 2021 I woke up and the swelling went down a little but now the area is very red. Slightly itchy.

throbbing pain in arm right after injection and low grade temp by feel. Then about 7-8 days later developed a deep cervical chain lymph node swollen.

Delayed reaction of 6 days. Strong headaches bordering migraine, swollen lymph nodes within left side of neck/throat, body aches mostly located at the hips, flu like symptoms. 8 days after injection the injection site got a small rash but disappeared 2 days after it appeared. 11 days after heart palpitations seemed to have started with no other side effects.

Bruising and redness following day of shot. Redness/swelling subsided after 3-4 days, however 8 days following the shot started up again. Red and itchy.

I felt arm pain in my left arm Around 4:00 pm, I started reaching for my face but I could not feel my face - it felt numb and tingly. That went on for two hours. There was no other droopiness juts facial numbness. My arm pain lasted for a good three weeks. It caused the lymph nodes under my armpit to swell. The pain went from my axilla Lymph nodes down to my left breast. I got a pinkish, reddish, itchy rash at the spot on the injection about a week later. I don't recall the date for the doctor visits - one telehealth and one in person. They wanted me to use Primrose oil to massage the oil. They told me to keep an eye on it. I still continue to get the pain under my arm pit from time to time. I have still been seeing physician about that.

Day of vaccine I felt perfectly fine. The next day i woke up with a swollen arm and very painful every time i loved it. Injection site was hot to the touch and it felt like a knot was under my skin. around 10:00am I began to feel feverish all over my body. I began to have the chills and began to feel tired. My body was achy as well and a headache developed. I slept from about 12:30PM to 6:30 PM and took acetaminophen at that time. Feverish feeling and chills broke after pill got into my system. Arm is still in major pain.

-Headache -Fever -Couldn?t lift left arm (injected arm) -Swollen lymph node left arm pit -Fever range 99.6-101.3 -Chills -Muscle and body aches (Above symptoms lasted for 48 hours) -Disoriented/feeling of outer body experience (Above symptom still current 64 hours later)

Day 1: arm was sore, and the area was red, slightly swollen, and hard Day 1-2: feverish, body chills, extreme fatigue, decreased appetite Day 6: large rash near vaccine site on left arm, extremely itchy, red, swollen, bumpy, hard Day 7: rash on arm still present, still itchy, more red, less swollen

After administration, patient had tingling in her left arm immediately and felt like her arm was "swelling immediately." After sitting down, her throat began to swell. She described it as "swallowing cotton balls", then "a large lump in her throat", then "narrowing of her throat so that it felt as if she was breathing through a closing straw." Patient was having an anaphylactic reaction to the vaccine. I (the pharmacist) administered an EpiPen once, then 50mg diphenhydramine IM, and called 911. Patient was evaluated by EMS and brought to the hospital for observation.

Body aches all over. Fatigue, rash on arm- not itchy, just swollen. Body aches continued throughout day, fever and chills around 7PM. Woke up next day fine except for rash on arm continues

Patient waited the suggested 15 minute observation period with no history of vaccine issues. After departing about 25-30 minutes after vaccination the patient noticed some moderate/severe throat closure, and went to an ER for treatment, and was given an EPI-pen, which seemed to aid the patient. They were discharged about 1-2 hours later The pharmacy was contacted about an hour or so after vaccination. The patient is well, with some minor swelling remaining.

I got the vaccine at 1:00 and by 5:00 my left arm was hurting at injection site - ibuprofen and cold therapy. Laying on that affected side is where it hurt. I woke up - vomited twice - nauseous; did visit through insurance on Saturday, the 23rd - at 8:30 am and Dr. prescribed Zofran for the nausea. Other symptoms: fatigue, headache and fever. Highest temp was 102.9. I only give myself Tylenol when my temperature when my temp is over 102. I took Ibuprofen as needed for the fever - helped the fever to go down. Mid Sunday, the lymph node started - on the left side of my neck and also under the armpit of that side. It was a quarter coin size of swelling under the armpit. For that I was drinking water and putting warm compress on the affected areas. The first symptoms lasted 3 days (resolved Monday). The lymph node swelling resolved Tuesday.

Sore arm and shoulder - lifting and pressure were painful for about 36 hours Lack of appetite - lasting 36-48 hours Severe lower back pain, beginning 12 hours following shot, currently experiencing Low grade fever - resulting in fits of overactive sweating - 24 hours post shot Swollen arm pit resulting in severe pain in injection arm - iced and took acetaminophen- relieved superficial pain, but still very sore.

Left arm sores, hard and swell. Feel tired and unable to focus my attention on work. The body temperature is higher than usual. Dizzy when gets out of the bed.

Red circle one inch in diameter around site of injection along with soreness and itchiness developed one week after receiving the first vaccine. At the same time, soreness of the lymph node in the armpit of the vaccine injection site is sore

Vomiting, hives, swelling of face lips thoart and closing of airways. Causing anaphylaxis shock, was in hospital 6 different times. Still having sever reactions 3 months after. Still causing airways to close and swelling of lips thoart eyes and neck was admitted to hospital and them not being able to stop the reaction after 4 shots of epi april 11 2021 I was admitted

101.9 fever, chills, muscle and joint pain, nausea, diarrhea, headache, face swelling All symptoms for 24 hours so far

I woke up 8 days after getting the vaccine (no side effects until now) with a circular warm, swollen red patch on my arm. I do not have a fever, it is not itchy. No other symptoms.

Patient went to the emergency room with heart palpitations, chest pain, fever, chills, swollen arm ,vomiting, diarrhea, fatigue ,headache. Patent was also told by the doctor that her WBC was elevated.

Vaccine given @ 03:50 pm; Patient complained feeling light headed @ 3:55pm, checked pulse 90 bpm, Pt was laid on the floor and raised leg for 5 minutes, patient complained getting cold and her throat was getting itchy and feeling hives. Injected Epipen 0.3mg @ 4:00 pm and called 911. Emergency arrived gave the patient 50 mg benadryl and checked blood pressure and heart rate . Pt was transported to hospital @ 4:30 pm . I called to check on the patient @ 6:00pm , she's doing fine : BP 130/80 , HR 98 , Oxygen @ 99.

raised swelling not painful over left arm at day 7, mildly itchy, also with small itchy papular rash sprinkled over body

Moderna COVID?19 Vaccine EUA Severe, migraine like headache Body aches Low-grade fever (<100) Extremely swollen left armpit lymph node that was accompanied with a burning/stabbing sensation and tingly fingers in left hand

Woke up this morning (one week after first dose) with a big red mark on my upper bicep that was warm to the touch. The area was swollen, as well as the under arm (lymph node?). Red mark has gotten larger over the course of the day, still swollen, tender, and hot to the touch. No other side effects, other than neck and hip pain the Monday after, but I am unsure it is related. The neck pain limited movement when trying to turn my chin over my right shoulder. The joint pain has gone away.

My arm was sore a couple hours on the first day, the next day I woke up achy with my arm more sore. I went to work and later started feeling pain under my eyes in my sinuses where I also noticed swelling. It is now the next day (2 days after the vaccine) and the pain and swelling has not gone away.

The day after my shot I got hives all over my body. They were giant hives. I started to take allergy medication to help with the irritation but it wasn't going away. I then called the place I got the vaccine and they hadn't reached back out to me in a timely manner so I did a virtual appointment. I then was prescribed some sort of Steroids for 5 days. I still have the hives mostly on my back and stomach. The hives are very hot but not ichy, just hurt to touch.

I got really tired around 12:00 pm and slept a lot both Thursday and Friday. My entire body ached for both Thursday and Friday. On Thursday around 5 pm I noticed the start of a cold sore on the corner of the right side of my lip. I haven't had cold sores since I was a teenager and used to have oral herpes outbreaks a lot as a child. But for about 10 years I've had zero problems. By Sunday that little cold sore infected both upper and lower lips all over, and my chin. On Monday it got even worse and inflamed with the use of Abreva. My face was on fire and I had to go to my doctor. My doctor then put me on Valacyclovir.

Pt called call center 4/29/21. Per pt, she received Moderna covid-19 vaccine on 4/28/21 in left arm. Pt said, she discovered a lump around left neck the evening of 4/28/21. Pt said, lump has increased this morning. Per pt, it looks round and hurts when touched. Pt also reported feeling tired. Pt has urgent care visit scheduled with provider today, 4/29/21

Thrombophlebitis of left leg- pain, redness, swelling. Started 11 days after 1st COVID vaccine. Treatment with warm compresses, NSAIDS, rest, elevation.

Patient received her second dose of Moderna COVID vaccine on Tues, 4/27, then developed palpitations on night of 4/29. She woke up that night at 3am with vomiting and 7/10 chest pain. Chest pain was described a substernal and symptoms occurred at rest. Additionally noticed an elevated heart rate. Her chest pain did not subside so she presented to the Hospital ER where she was noted to have elevated trop from 1.8 to 3.5. TTE at bedside showed reduced EF to 40%, global apical hypokinesis. At healthcare facility, cardiac cath was normal and EF appeared normal on wet read of repeat TTE. She was started on captopril (transitioned to lisinopril on DC) and metoprolol. She will be discharged with follow up with physician.

Swollen Lymph nodes under left armpit and left supraclavicular. It started from 3 days later after the injection, for the first 3-5 days, the armpit nodes were hurt, but then the pain ended. However, till today, there are still one mode under left supraclavicular and two nodes under left armpit that are not completely back to normal.

I have TERRIBLE pain in my left armpit. Has been going on for two days. The pain radiates and is a bit swollen as well.

After my second dose a day later I got a big red bump on my right fore arm that started to itchy, a few hours later my entire body was full of rashes and are very itchy, my face is the worst it burns and is very itchy. It has been 5 day since my second dose and the rashes have not gone away and the itchiness has worsen

BCG vaccine scar became red, swollen, and itchy. BCG vaccine scar is about 3 inches lower from COVID vaccine injection site.

Site: Redness at Injection Site-Severe, Site: Swelling at Injection Site-Severe, Systemic: Allergic: Difficulty Breathing-Medium, Systemic: Allergic: Itch (specify: facial area, extremeties)-Medium, Systemic: Allergic: Itch Generalized-Medium, Systemic: Allergic: Rash (specify: facial area, extremeties)-Medium, Systemic: Allergic: Rash Generalized-Medium, Systemic: Allergic: Swelling of Face / Eyes / Mouth / Tongue-Medium, Additional Details: patient recieved vaccine at 10am. Reaction did not occur until 2 pm.

Swelling/lump, redness, itching, and bruising in area still today. Thought I should report to note as a symptom for people with blood thinners as it?s been three weeks since my second dose, the bruise is still there, it?s light, but there. Bruising is a side effect of eliquis so could be enhanced by the vaccine

Swollen bump on lower neck on the right side (side of vaccination site). Bump was extremely tender at first, bump has not gone down after 4 days and neck is extremely stiff and sore but more tolerable to touch.

It was a swollen lymph node and they couldnt give anything other than ibuprofen. Went to PCP where I got imaging done. It went away by itself.

01/12/21 (First dose on 1/9): Exhaustion/confusion (lasted for about three days), recognized episodes of tachycardia that lasted for weeks; severe pain in right arm at vaccination site that lasted about 2 days. 02/9/21: Received second dose of vaccine on 2/6/21, recognized raised, oblong, red rash not at the location of the vaccination site on the deltoid, but on the top of the upper arm and down near the antecubital fossa that slowly crept down the arm over several days, was gone in about a week; severe arm pain for about 2 days; episodes of racing heart continues, was relieved with rest. 03/15/21-03/26/21: Exhaustion; recognized multiple episodes of tachycardia that was not relieved with rest (around 140 bmp, each episode lasted between 3-6 hours). 03/23/21-03/24/21: Pain in right arm 03/26/21-04/2/21: Recognized exhaustion/confusion, tachycardia that was not relieved with rest. 04/2/21: Right arm swelling and pain. Tachycardia (140 bmp), not relieved with rest. Chest pain/tightness. Arm turned purple and all the vasculature was present in the right arm and chest. Admitted to hospital, ultrasound revealed the subclavian vein was completely occluded down to the basilic vein near the elbow. CT scan showed pulmonary emboli in both lungs. Was placed on heparin drip and released from hospital on 04/4/21. Started on 10 mg Eliquis BID for one week on 4/4, now on 5 mg Eliquis BID for 6 months. 05/19/21: Received diagnosis of Factor V Leiden heterozygous mutation. Arm pain/swelling remains periodically.

I had a large, hot, solid bump on my arm. It itched and got red as well as progressively larger over the following days. It continues to itch. I am applying cortisone cream and an ice pack.

After receiving the COVID vaccine, Patient started to develop itching all over her body. She was brought back to exam room. Heart and lung sounds normal. Vitals stable: BP: 115/67 and Pulse: 88, O2 sat 95%. No visible rash but patient scratching a lot and causing excoriation on skin. No SOB, chest pain. No swelling or tightness of throat. Patient breathing comfortably. Also reported dizziness which resolved when laying down. Patient was given 25 mg Benadryl with little improvement. Given an additional 25 mg after 15 minutes. Patient then reported she felt like her hands were swelling-palms of hands were pink and warm to touch. Because patient was not noticing any improvement in her symptoms and scratching a lot, patient was sent to ER via ambulance for further evaluation and monitoring

Severe shoulder and arm pain with swelling after 2nd dose of Covid vaccine. Unable to use left arm at all for 2 weeks and then slowly got more mobile. Six weeks after still had limited mobility and pain. Made a doctor appointment and was diagnosed with frozen shoulder and prescribed prednisone and specific exercises. Was told if this doesn?t work will have to have shots in my shoulder and physical therapy.

Red/swollen face after 30 minutes lasting for 1.5 hour, 2 hives on opposite arm & 1 on neck after 1 hour lasting for 0.5 hour. All adverse reaction went away after taking Benadryl & with time. I called the pharmacy I got the vaccine at and they said to go to urgent care in case I need an epi pen, but I just monitored it at home.

May 2- Urgent Care. Presents today with a shooting pain behind the left ear that radiates down her neck since 0200 today. June 12- ER. Outcome: Diagnosed with Epicardial Fat Necrosis. Presenting with sudden onset, sharp left-sided chest pain radiating to the left shoulder since 1100. Pain rated 9/10. Pain improved by leaning forward. Pain is worse lying supine. Pain is worse with deep inspiration. Tried ibuprofen and Tylenol with minimal symptomatic improvement. No history of similar symptoms. Patient's presentation consistent with epicardial fat necrosis given increased attenuation of pericardial fat on CT, trace pleural effusion, and left-sided pleuritic chest pain worse with postural changes. Pericarditis considered given postural component of patient's symptoms EKG without evidence of pericarditis, ACS unlikely given no ischemic changes on EKG and negative troponin. Pulmonary embolism considered given sinus tachycardia, pleuritic chest pain, and mildly elevated D-dimer, but unlikely given no clinical signs of DVT, dyspnea, or pulmonary embolism on CT. 6/13 ER This is a 25 year old patient who presents with chest pain. Considered the possibility of pericarditis given patient's pleuritic and positional chest pain. However, her EKG continues to show no signs of such. Patient's troponin is not elevated making myocarditis less likely. Dissection were considered but felt to be extremely unlikely given overall presentation and imaging deferred. PE highly unlikely given negative CT PE study yesterday. No vomiting to suggest esophageal perforation. No cancer history to suggest pericardial effusion. History and exam not suggestive of pneumonia or pneumothorax. Suspect patient's symptoms are due to the epicardial fat necrosis seen on previous CT chest. Patient was treated with 15 mg of ketorolac with minimal improvement and pain. She was then given 10 mg p.o. oxycodone, 1 g acetaminophen, a L of IV fluid and ondansetron with some improvement in symptoms. Patient was discharged home with a prescription for oxycodone and ondansetron. Patient was provided with return precautions prior to discharge. Impression: Chest pain, epicardial fat necrosis

Chills, fever and headache starting about midnight at the end of Sunday night and I went to work and had to leave within an hour. I took Tylenol about 10:00 or 11:00 that day. I felt sore and feverish until about noon on the 6th. On the 12th of June, I had acute pain in my lower right side. I started noticing them at about 08:00 am that morning. I originally went to Urgent Care and then they sent me to hospital around 07:00 pm and I had the appendix out around 04:00 am on the 13th. They gave me antibiotics in ER until they took it out on 13th. I was given three pain meds - Tramadol; extra Strength Tylenol; Extra Strength Ibuprofen. I had complications on Monday the 14th - ended up back in ER - I had nausea and couldn't stop throwing up. I was given Zofran. I took that the next two days after which nausea and constipation had passed. I'm in the process of recovering. I'm getting better every day. It will be six weeks before I won't have limitations.

Moderna COVID-19 Vaccine EUA: Beginning 05/14/21: Ongoing Extreme fatigue, complete loss of appetite, >10% weight loss over 4-week period. 5/16/21: Severe mast cell reaction 05/16/21 -- treated with IV Benadryl, IV famotidine, oral Ativan. 5/17/21: Leg pain 5/18/ 21: Nausea 5/22/21: Large joint pain; treated with topical compound cream (ketoprofen, ketamine, lidocaine, cyclobenzaprine) 5/26/21: Tachycardia 130 bpm; shortness of breath (S.O.B.); Week of 6/2/21: Full body tenderness (flu-like); 6/8/21: Major headache -- treated with 30mg IV Toradol (+ IV Zofran); consulted PCP; 6/9/21: ONGOING Joint paint (hips, knees, elbows, wrists); Gait disruption begins. No longer able to walk 10 meters. 6/10/21: Burning pain in heels, large left toe joint swelling, right forearm swelling; 6/11-12/ 21: Leg/ foot pain continues-- treated with IV Toradol (+ IV Zofran); 6/12/21 to PRESENT: began ongoing but intermittent electric shock-like pain in feet; radiating sciatic pain; headaches Level 7; tachycardia; adrenaline rushes; Hot flashes; Coat hangar pain. 6/17/21 PCP prescribed Norco 5mg; Takes maximum of 1/2 tab b.i.d.; 6/21/21: Consult with cardiologist; 6/23/21: Decadron burst 8mg 5 days; begin taper and return to 8mg 3 more days; Begin taper dosage 7/3/21; neuropathy not relieved, appetite increased. 6/29/21: Gabapentin -- reacted with severe headache, discontinued; 7/2/21: Began extreme blood pooling in feet (dark purple) 7/5/21: Hot burning feet; begin to have pain when extending arms or leaning forward more than 30 degrees. 7/6/21: No longer perceives hot water on feet; Resurgence of hyperhidrosis in hands & armpits; ongoing. 7/9/21: intermittent numbness on left shin; ongoing major joint pain; continued electrical shock-like pain in feet. Gait disruption continues. Progressive neuropathy. V Now unable to ambulate 10 Meters without walker assistance or wheelchair.

Swollen cheeks. Throbbing throat. Numbed mouth (felt like I had lidocaine for dental work). Very dizzy and disoriented. Heavy chest. Headache.

seizure; shortness of breath; mucus/was throwing up everything including mucus; She had reduced appetite; upset stomach; nausea; Vomiting; felt like she was going to die, like she got hit by a car; fever; coughing; unable to move; have no energy/body is very weak/She was weak; unable to go to work, and lost her job; arm was swollen; arm was itchy; 2nd dose after 38 days; This spontaneous case was reported by a consumer and describes the occurrence of SEIZURE (seizure) in a 25-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 027D21A and 0110214) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. The patient's past medical history included Bacterial vaginosis. Previously administered products included for an unreported indication: FLU (Patient regularly takes the flu shot). Concurrent medical conditions included Diabetes, Asthma, Seizure, Anxiety and Arthritis. Concomitant products included SITAGLIPTIN PHOSPHATE (JANUVIA) for Diabetes, LEVETIRACETAM (KEPPRA [LEVETIRACETAM]), PROCATEROL HYDROCHLORIDE (PRO-AIR) and GLUCOSE for an unknown indication. On 01-Jun-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 08-Jul-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 08-Jul-2021, the patient experienced PERIPHERAL SWELLING (arm was swollen), PRURITUS (arm was itchy) and INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (2nd dose after 38 days). On 09-Jul-2021, the patient experienced IMPAIRED WORK ABILITY (unable to go to work, and lost her job), MOVEMENT DISORDER (unable to move), ASTHENIA (have no energy/body is very weak/She was weak), COUGH (coughing), VACCINATION COMPLICATION (felt like she was going to die, like she got hit by a car) and PYREXIA (fever). On 10-Jul-2021, the patient experienced SEIZURE (seizure) (seriousness criterion medically significant), DYSPNOEA (shortness of breath), SECRETION DISCHARGE (mucus/was throwing up everything including mucus), DECREASED APPETITE (She had reduced appetite), ABDOMINAL DISCOMFORT (upset stomach), NAUSEA (nausea) and VOMITING (Vomiting). The patient was treated with CETIRIZINE HYDROCHLORIDE (ZYRTEC [CETIRIZINE HYDROCHLORIDE]) for Adverse event, at an unspecified dose and frequency and Physical therapy (breathing exercise) for Dyspnoea. On 08-Jul-2021, INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION (2nd dose after 38 days) had resolved. On 10-Jul-2021, SEIZURE (seizure), DYSPNOEA (shortness of breath), PERIPHERAL SWELLING (arm was swollen), PRURITUS (arm was itchy) and PYREXIA (fever) had resolved. At the time of the report, IMPAIRED WORK ABILITY (unable to go to work, and lost her job), MOVEMENT DISORDER (unable to move), ASTHENIA (have no energy/body is very weak/She was weak), SECRETION DISCHARGE (mucus/was throwing up everything including mucus), COUGH (coughing), VACCINATION COMPLICATION (felt like she was going to die, like she got hit by a car), DECREASED APPETITE (She had reduced appetite), ABDOMINAL DISCOMFORT (upset stomach), NAUSEA (nausea) and VOMITING (Vomiting) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 09-Jul-2021, Body temperature: 101 (High) High. The patient reported her A1C was at 9 for at least 3 months to date. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Additionally, this is also a case of inappropriate schedule of vaccine administered for mRNA-1273 (lot #027D21A). Further information has been requested. This case was linked to MOD-2021-256558 (Patient Link). Most recent FOLLOW-UP information incorporated above includes: On 14-Jul-2021: Case upgraded to serious; Patient medical history, lab data, concomitant and treatment medication, new events added, and narrative updated.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Additionally, this is also a case of inappropriate schedule of vaccine administered for mRNA-1273 (lot #027D21A). Further information has been requested.

thrombocytopenia; has a continued stomach problem that she went to the emergency room for; headache; her face was swollen a little bit/looked a bit different/still had her swelling; This spontaneous case was reported by a consumer and describes the occurrence of BLOOD DISORDER (thrombocytopenia) in a 25-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. No Medical History information was reported. In May 2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 14-Jun-2021, the patient experienced SWELLING FACE (her face was swollen a little bit/looked a bit different/still had her swelling). On an unknown date, the patient experienced BLOOD DISORDER (thrombocytopenia) (seriousness criterion hospitalization), ABDOMINAL DISCOMFORT (has a continued stomach problem that she went to the emergency room for) and HEADACHE (headache). At the time of the report, BLOOD DISORDER (thrombocytopenia) and SWELLING FACE (her face was swollen a little bit/looked a bit different/still had her swelling) had not resolved and ABDOMINAL DISCOMFORT (has a continued stomach problem that she went to the emergency room for) and HEADACHE (headache) outcome was unknown. No concomitant medications were reported. Treatment included a blood transfusion. On 14 Jun 2021, the patient had a swollen face and looked a bit different. Two weeks later, the patient had stomach problems which resulted in a visit to the emergency room (ER). While in the ER, the patient had unspecified blood work performed, which revealed her blood counts were dropping. The patient was released home and was to follow-up with their family doctor. A week later, the patient complained of a headache and still had swelling in the face. The patient's red blood cells (RBCs) were down below normal. The hospital gave the patient a blood transfusion and had a bone marrow biopsy performed, results not provided. At the time of this report, the patient was hospitalized. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

Patient reports swelling, redness and tingling in arm. She reports this happened with the first moderna injection, also happened, but more extreme, the second time

4:00pm- Received vaccine (Moderna dose 1) 4:10pm- Started experiencing throat swelling, trouble breathing, increased anxiety. Alerted pharmacist that I was having a reaction and they have me a bottle of water. 4:25-4:30pm- Alerted pharmacist again that the reaction was still going on and I was given a 25mg Benadryl. It was hard to swallow but I was still able to take it. 4:30pm-5:30pm- Waited to see if the Benadryl would help but it did not. Had to call a family member to take me to ER. 6pm-8pm - Went to ER to get checked out. Doctor said I was having an allergic reaction (similar to a shellfish reaction) and was given IV steroid (Dexmethosone) and some fluids.