Moderna

The individual starts to show signs of anaphylaxis reaction some minutes after vaccination by the nurse. Said"I am not feeling good." Upon assessment, the individual is leaning his head backwards, unable to read how many fingers I held up; complained "can't see"; slow in responding. The individuals appears to be losing consciousness; eyes closed. Color of face pale. HR: 47; Pusle Ox 95%. RR:16. BP 112/64. Epipen 1 dose administered L leg IM. 911 was called. Continue to monitor and check vital signs. BP 143/75, HR: 54 and pulse ox: 94%. At 0850:EMS arrived. VS remain stable. HR: 62; Pulse Ox 94%. The individual starts to open up his eyes and responding. Parents at his side. He is taken to the ER. Followed up with the patient's parent, mom and is stable and doing better.

He was given the Moderna COVID vaccine first dose on 1-15-2021. 2.5 weeks later he complained of constant abdominal pain that lasted two days. No fever/chills, nausea/vomiting, diarrhea/constipation, no visible blood in stool or urine, no abnormal color or volume of urine. No preceding illness of any kind. He is tested for COVID weekly at college and was always negative including on 1-16-2021 He went to a freestanding ER where CT Abd without contrast showed normal appendix but mesenteric adenitis. White count was normal but creatinine was 2.8! He was given 2 L of fluid and recheck showed Cr 2.8 again. Urine dipstick 2+ proteinuria and microscopic hematuria. He works out 6 days/week but nothing unusual in the recent workout history. CPK was normal. Serum myoglobin slightly elevated at 94. He doesn?t take supplements, creatine, drugs, energy drinks, coffee or any medications. He was advised to hydrate copiously which he did. He was admitted for work up two days later. Repeat Cr was 3.1. ESR was 45 and CRP 2.26. RF, ANA, ANCA negative. Complement levels C3 and C4 normal. Uric acid and LDH normal. Amylase and Lipase normal. UA showed no protein or blood. IVF given overnight and kidney biopsy planned for the next day depending on that mornings labs. That morning Cr came down to 2.4. PTH was 127, Vit D 12.7, Calcium normal. SPEP normal and UPEP normal. Urine drug screen normal. Kidney biopsy cancelled and he was discharged. Cr two days later (2-10-2021) was 1.68

Saturday morning after vaccine was administered: Tennis ball size oblong lump noted between eyebrows at middle of forehead. Felt "funny", cheeks flushed, no apparent fever (not hot to touch). Lump itself was not red, painful or itchy. it was definitely "noticeable". Headache on the day he received vaccine, but no other reports of headache following. Tends to be anxious and has a history of "passing out" when leaving a dentist's office in the past.

Received first dose of Moderna vaccine today around 2:30 pm. Reports 2 minutes later, felt left side of throat "swell" and was uncomfortable. Also felt mild chest discomfort. Symptoms resolved after about 3 minutes, so he finished his 15 minute observation time, and left the clinic. He returned approximately 15 mins later, and informed the ER MD here in the clinic that his throat swelling and tightness had returned and that he now had and some difficulty breathing. He was answering questions appropriately, appeared in no distress. At 1510 VS taken: BP 122/74, O2 sat 100%, P 73, RR 18. Skin color pink/normal. ER MD advised patient be taken to ER and he called report there. Patient was taken via WC right away to ER with MD, and RN and myself. Anaphylaxis kit brought. But not used. He was stable during transport. In ER he c/o more throat tightness, and it appeared that the left side of his neck was mildly swollen. He then c/o bilateral pedal numbness and also some difficulty breathing. Care was assumed by RN and report was given to her. He was able to call his parents prior and remained stable at the time we departed the ER. NP

dizziness/light headed, cold, clammy and sweating in face, fainted, then vomited. Occurred 4 hours after shot was given.

He was admitted to Cardiovascular Medicine on 4/11/21 with acute idiopathic myocarditis, the etiology was unclear but considered due to recent COVID vaccination vs viral infection. He presented with elevated troponin and initially elevated ESR and CRP. CTA of coronary arteries was on done on 4/12 and showed normal coronary arteries. TTE was done on 4/13 and showed a normal LVEF of 65% and normal LV size and wall thickness. His RV size was mildly enlarged and has mildly elevated right atrial pressure. There was no significant valvular disease. Cardiac MRI was done prior to discharge and he will follow up with cardiology for the final results. He was having some intermittent chest pain and SOB and was recommended to use OTC ibuprofen 600 mg BID per cardiology. Reports that his chest pain and shortness of breath is slowly resolving. His symptoms are mild and infrequent.

Pt received vaccine 4/20/21; developed profound HA, lethargy, diarrhea with symptoms persisting 7 days. CRP elevated, platelets decreased. lead to hospital admission. likely only 24 hours

After 2nd vaccine dose developed myalgias, fever, chills, chest pain and shortness of breath hours afterwards which persisted and continued to worsen. Initial work up so far in the hospital appears to be myocarditis and is he is being admitted to telemetry.

Patient is a healthy 18 year old male with no history of Covid-19. Received 1 dose Moderna vaccine 5/8/21. Felt malaise, febrile to 103.5 that evening, 5/9/21 began experiencing chest pain. 5/11/21 presented to emergency department. Diagnosed Myopericarditis of unknown origin. Cannot exclude inflammatory response from vaccine as etiology.

Took a generic version of Miralax and had anaphylactic reaction and ended up in ER; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of ANAPHYLACTIC REACTION (Took a generic version of Miralax and had anaphylactic reaction and ended up in ER) in an 18-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 001C21A) for COVID-19 vaccination. No Medical History information was reported. On 22-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 12-May-2021, the patient experienced ANAPHYLACTIC REACTION (Took a generic version of Miralax and had anaphylactic reaction and ended up in ER) (seriousness criterion medically significant). At the time of the report, ANAPHYLACTIC REACTION (Took a generic version of Miralax and had anaphylactic reaction and ended up in ER) outcome was unknown. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. Concomitant product use was not provided by the reporter. Treatment information was not provided. Company Comment: Based on the reporter's description of the event after taking Miralax and the temporal relationship occurring closer to Miralax dosing, the event is assessed as unlikely related to mRNA-1273.; Sender's Comments: Based on the reporter's description of the event after taking Miralax and the temporal relationship occurring closer to Miralax dosing, the event is assessed as unlikely related to mRNA-1273.

after first dose, urticarial/welt rash after second doe, more diffuse urticarial rash with swelling of face, neck, hands and feet and scrotum

Patient received second Materna vaccine 5/28/2021 around 630 pm. Around 10 PM felt fatigue and headache. Felt very fatigued and unwell and slept most of 5/29 - 5/30. On 5/31, began experiencing chest discomfort radiating to left arm and palpitations. Presented to hospital which was notable for abnormal EKG with diffuse ST elevations and PR depressions, troponin peak of 25. TTE revealed low normal systolic function with EF 50%, no valvular disease or wall motion abnormalities. Cardiac MRI revealed subepicardial delayed myocardial enhancement in the mid, apex lateral wall of the left ventricle and adjacent pericardium consistent with myopericarditis. Patient was treated with colchicine and improved. Infectious work-up for cardiotropic viruses were sent, viral swab was notable for positive rhinovirus/enterovirus. Patient's presentation and timing of vaccine should be looked into as it is unclear wheter this presentation can be entirely due to presence of virus as above. This is notably at least the second presentation of teenager with myopericarditis on this cardiology service in the past 2 weeks in setting of recent Covid vaccination.

Patient had received first dose of Moderna on 04/26/2021. Lump on clavicle noted one week later. Sensitive upon touch.

2 days after the vaccine, developed Right Lower Quadrant pain - varying in severity from 2 to 7 out of 10, intermittent. Suspected mesenteric adenitis, possibly secondary to vaccination. DDx includes appendicitis. Plan - observe at home, follow up if worsening symptoms or not resolving later this week.

Endorsed acute chest pain around 1200 on 6/21 initially that seemed to get better. On the early morning of 6/22 at 0400, the pain woke him up from sleep with a 7-8/10 in severity. At this point it was extremely painful for the patient to breathe but he denies shortness of breath. Denies radiation of pain, felt better when he was lying down, worse when sitting up, and was extremely bothersome while ambulating. Presented to Hospital and was found to have elevated troponin ( 7.25--13.00--2.52). Transferred to another Hospital Cardiac MRI supported the diagnosis of myopericarditis. By the time of transfer to Hospital, hos chest pain had resolved. He was treated with a 6 week course of ibuprofen and colchicine.

Systemic: Allergic: Anaphylaxis-Medium, Systemic: Fainting / Unresponsive-Medium, Systemic: Flushed / Sweating-Medium, Systemic: Hyperventilation-Medium, Systemic: Hypotension-Medium, Systemic: Shakiness-Medium, Systemic: Tingling (specify: facial area, extemities)-Medium, Systemic: Weakness-Medium, Additional Details: Patient was administered vaccine in left deltoid. Patient was seated in chair when vaccinated. Patient walked about 5 or 6 steps to waiting room chair to sit down and wait post vaccination. About 90 seconds to 3 minutes post vaccination the patient was seated in chair and fainted forward. Was holding conversation with father in the next chair to him and fainted from chair to the floor. Patient was aware after about 5 to 7 seconds post fainting, arms and hands were rigid.

Patient initially had muscle soreness in the left arm for about 4 days which did subside. 2 days later he developed an enlarged axillary lymph node which continues to be painful and a 3" x 2.5 inch erythematous patch at the injection site. All symptoms are slowly dissipating but do continue at this time. No constitutional symptoms.

On second day after vaccination, Patient began to notice cutaneous lesions on bilateral dorsa of feet and both palms. The dorsa of his feet had a slightly raised, pruritic erythematous rash that, over the course of the day, extended in places near to the ankle. Though not warm to the touch, Patient explained that they felt hot and painful. There was slight swelling. By 1/24/21, there was less swelling, and discomfort and the erythematous rash had become eczematous in places and thicker than the previous day. The palms didn't have an appreciable rash. However, Patient felt much discomfort there (not exactly painful) and some paresthesia. He felt that his fingers were swollen. By 1/24/21, the discomfort in both palms was worse.

Immediately after the vaccine was administered I experienced the usual side effects of mild headache, fatigue and localized redness and swelling Around 11pm the night the vaccine was administered I developed a migraine that resulted in blurred vision. and when I checked my temperature it was approximately 104.9 degrees Fahrenheit.By the next morning, approximately 7am, I was weak to the point I could not get out of bed myself, I was nauseous that resulted in a single Emesis episode approximately 8am, I had mild swelling of my face since 7am, between 7:30am and 12pm, I had multiple times where I would temporarily lose my vision. Throughout 1/25 I continued to have a fever ranging from 102 degrees Fahrenheit to 103 degrees Fahrenheit. At approximately 8am and 1pm I took two acetaminophen pills each time which alleviated the migraine and to an extent helped with the visual deficit episodes. Throughout 1/24 and 1/25 I suffered with extreme chills resulting in shivering that lasted for several minutes despite a room temperature of approximately 90 degrees Fahrenheit and covered in two blankets. PCP was consulted via telephone and she advised to go to the hospital via EMS given the high grade fever, abnormal vitals and severity of symptoms

Hives at injection site starting 7 days prior. Swollen lymph nodes side of injection. Red area and warm to the touch at injection site starting 7 days prior.

19 yo medically complex M with prior COVID infection in Dec 2020 who received first dose of the Moderna COVID vaccine on 3/4 as well as Epo shot (for chronic anemia secondary to CKD). Recently admitted for MRSA sacral abscess and had recently been discharged to complete treatment on oral Bactrim. On 3/6, developed worsening diarrhea, decreased urine output, facial and tongue swelling, and altered mental status. EMS was called and patient was brought to the ED. Upon presentation, noted to have hypotension and was fluid resuscitated. Initial blood gas with hypercarbia, and he was intubated for airway protection. CXR was non-focal. He was started on empiric vancomycin and ceftriaxone, although these were discontinued with negative blood and urine cultures. Repeat respiratory film array was negative. Patient intubated 3/6-3/10.

Currently having it. I have a swollen face. Blurry vision. Difficulty standing. Shallow breaths. Headache. Chills. Body aches. 101 fever. Unable to sleep but very tired. Not able to breather through nose. Sore and numb right arm. Tingling of my limbs. Occasionally sharp pain in muscles. I got the shot at 11 and was just fine but I had work. I drove for a little over an hour and progressively my arm got weaker. I did physical labor until 10 pm and then started some school work, but found my arm almost unable to move and my mood was deteriorating. When I went to bed and lied down, it hit me. It is 4 am and it is still going strong.

BEGAN FEELING CHEST PAIN AND LIGHTHEADEDNESS BEGINNING 3/14, THE DAY AFTER GETTING THE VACCINE. HE PRESENTED TO THE EMERGENCY ROOM ON 3/17 WITH WORSENING OF CP THAT WOULD NOT GET BETTER WITH NSAIDS, PAIN RADIATING DOWN LEFT ARM. TROPONINS NOTED TO BE ELEVATED, PT ADMITTED TO INPATIENT ROOM FOR CARE ON 3/17. TESTING DONE AND PT TREATED FOR MYOCARDITIS POSSIBLY SECONDARY TO COVID 19 VACCINATION. DC'D HOME ON 3/24 WITH LISINOPRIL AND PREDNISONE. ORDERS TO FOLLOW UP WITH DR.

4 seizures; anaphylaxis; This spontaneous case was reported by a physician (subsequently medically confirmed) and describes the occurrence of SEIZURE (4 seizures) and ANAPHYLACTIC REACTION (anaphylaxis) in a 19-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 037B21A) for COVID-19 vaccination. The patient's past medical history included Seizures. Concomitant products included ACETAMINOPHEN, ATOMOXETINE HYDROCHLORIDE (STRATTERA), CLONIDINE, DIAZEPAM (VALIUM), FLUOXETINE HYDROCHLORIDE (PROZAC), LEVETIRACETAM (KEPPRA), ONDANSETRON (ZOFRAN [ONDANSETRON]), OXYCODONE and OMEPRAZOLE (PROTONIX [OMEPRAZOLE]) for an unknown indication. On 09-Apr-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 09-Apr-2021, the patient experienced SEIZURE (4 seizures) (seriousness criteria hospitalization and life threatening) and ANAPHYLACTIC REACTION (anaphylaxis) (seriousness criteria hospitalization and life threatening). On 09-Apr-2021, SEIZURE (4 seizures) had resolved and ANAPHYLACTIC REACTION (anaphylaxis) was resolving. For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered SEIZURE (4 seizures) and ANAPHYLACTIC REACTION (anaphylaxis) to be related. Hospitalization unknown meds. This is a 19 -year-old, male patient who received Moderna COVID-19 Vaccine) (batch no. 037B21A) and experienced seizures and anaphylactic reaction one day after receiving second dose of vaccine. Medical hx includes seizures Some relevant conmeds atomoxetine, clonidine, diazepam, fluoxetine, levetiracetam, and oxycodone were provided. Very limited information has been reported at this time. No further information is expected Reporter did not allow further contact; Sender's Comments: This is a 19 -year-old, male patient who received Moderna COVID-19 Vaccine) (batch no. 037B21A) and experienced seizures and anaphylactic reaction one day after receiving second dose of vaccine. Medical hx includes seizures Some relevant conmeds atomoxetine, clonidine, diazepam, fluoxetine, levetiracetam, and oxycodone were provided. Very limited information has been reported at this time. No further information is expected

left arm pain beginning 3 days post vaccination; treated at home with OTC pain relievers and active ROM; presented to clinic 2 days after symptom onset; scant ecchymosis noted to vaccination site; site visibly high on deltoid muscle; diagnosed with bursitis and treated with Ibuprofen prescription and rest

The patient was ok when he received vaccine and was advised to stay around pharmacy for 15 minutes. He started to develop red dotty rash in the arms and legs and arms and legs was swollen. was seen by Dermatologist and was give prednisone for 10 days. also had biopsy and the results came back normal. There was no other symptoms other than the rash. (no itching or aches). The rash decreased over period of time and the Dermatologist said it is ok to get the 2nd dose of Moderna and was given 2nd dose on 4/18/2021.

Developed Fever and chills during the night 4/8/2021. Felt fatigued with intermittent chills on 4/9/2021 and then fever and chills again that night. Felt fine Saturday 4/10 and then Sunday 4/11 developed low grade chest pain lasting 2 hours and resolved with Advil. Awakened at 5am on Monday 4/12 with severe diffuse chest pain requiring hospitalization and treated for myopericarditis.

Seen 2/22/21 for hives/swelling hands and feet since 2/21 PM (started the day after receiving the vaccine). No respiratory or sytemic symptoms. Treated with Benadryl as needed.

Chest pain 2 days after COVID vaccine. Midsternal cramping, pressure-like associated with shortness of breath. Pain resolved, but then returned later in the evening when lying down to go to sleep. Symptoms - chills, fever, shortness of breath, chest pain COVID 19 vaccine related myopericarditis cannot be ruled out

After the vaccine I had a sore muscle at the vaccination site, but that went away after a day. 5 days after receiving my first Moderna vaccine, I noticed a swollen lymph node under my armpit on the same arm that I received the vaccine on (left armpit), but went to sleep not thinking anything of it. I woke up at 9am the next day to intense body aches and skin sensitivity and the lymph node even larger. The body aches have remained all day, but have subsided from rest. I went to my local urgent care center to get a Covid-19 rapid test and it came back negative.

I have swelling in my under arm on my left side. its painful and makes it difficult to sleep or move around

Patient developed fast heart rate, chest pain - seen by PMD who admitted patient to hospital cardiac scan showed Myocarditis. Symptoms started 5/1/21

Lymphadenopathy noted on exam to chest wall and left axillary area. Reassured patient this is consistent with a relatively common side effect of COVID vaccine. Lymphadenopathy is tender, small on exam and consistent with reactive etiology. Recommended warm compresses, OTC analgesics and follow-up with primary care as needed. Return to clinic if having skin changes, fevers or feeling otherwise unwell in the meantime. Patient verbalized understanding of agreement with plan.

Patient was admitted to the hospital with myopericarditis. Presented to the ER with chest pain. He was admitted for trending troponin levels and monitoring for arrhthmia/cardiac function. Troponin peaked at 10.8 on 5/15.

After having the shot, hedeveloped left arm pain and did develop some lymphadenopathy in his left axillary region. He was dealing with nausea and dizziness, and the following day, he went to work, although he was feeling a bit ill. While at work, he was found to have a fever, so he was sent home. He has been having hot and cold flashes since then. He has had a poor appetite. He has had a dry mouth and trouble sleeping. One day prior to admission, he then developed a chest pain that became constant and persisted, so he came into the emergency department on 05/19/2021 for further care. He has developed myocarditis after receiving the first of his Moderna Coronavirus Disease 19 vaccines.

5 days after Moderna Covid Vaccine, patient developed swelling, redness and tenderness over hands/wrists/knees/ankles and feet.

He started with fever and chills on the evening of the day he received the vaccine, Also severe pain in lower sternum, emesis \over the next 2-3 days developed abd pain of lower abd, cough, resp distress, waves of fatigue and hyperventilation, on 5/10 noted full body rash which was itchy, last fever was on 5/13/21, on 5/12 had blood shot eyes, 5/14 - peely skin on palms and face and felt thightness in face

Developed acute onset chest pain and shortness of breath on 5/11 with nausea/vomiting x1. He didn't have any prior systemic symptoms, URI symptoms, rashes, and was in his usual state of health. Other ROS was negaitve other than longstanding right shoulder pain without weakness.

Hives and rash all over the body, Angioedema like symptoms (significant swelling of the lips eyes, and face)

Patient received vaccine series at a separate facility. I do not have access to this information. He reported receiving Moderna dose #2 on Tuesday, June 8. Within hours, he began to have chest pain, shortness of breath, general body aches and fatigue. Chest pain was worse with deep breath and worse with supine position. On Friday, June 11, he presented to The Clinic at with these complaints. He was noted to be in evident severe discomfort, though not in respiratory distress. Vitals as follows: pulse 82 and regular, BP 139/68, respiratory rate 20, temperature 99.2 oral, SaO2 98% on room air. Exam was notable for absence of a pericardial friction rub. Lungs were clear to auscultation. he had no rashes and no remarkable tenderness of the body to palpation. Extremities were without edema. There was no sign of clinical heart failure or cardiovascular insufficiency.

Fever the morning following vaccine then development of chest pain. Found to have elevated Trop levels and ST elevation on EKG. Elevated CRP, Sed Rate and Cardiac MRI consistent with Myocarditis.

2nd dose received at 11am. Mild arm soreness immediately after. Remained for 2 days with no increase in severity then dissipated. Lymphnode discomfort mild beginning 2 hours after vaccination. Remainder for 2 days with increase to medium severity approximately 8 hours after receiving vaccination. Nuchal rigidity began 8 hours after receiving 2nd dose, mild -> medium severity. Dissipated 1 day after receiving shot. Mild photosensitivity to light began approx 9 hours after receiving shot. Dissipated by next morning. 9 hours after receiving vaccination, medium fever developed. Baseline temperature is 96.4. At 9 hours after vaccination, developed fever at 99.7*F. At 11 hours after, temperature was 100.9*F, with severe discomfort and body aches / chills. Dissipated by following morning. Hope this helps. Thank you.

The above patient received a COVID-19 vaccine on 03MAR21 @ 1440. He came to the EH&S office on the morning of 04MAR21 complaining of left arm pain, fatigue, headache, muscle pain, joint pain, chills, and nausea/vomiting. He was evaluated by a healthcare provider who noted mild swelling and a small knot was felt in his left arm. He is to follow-up with our onsite nurse or his medical provider if his condition worsens.

8 days after receiving vaccine, pt developed delayed urticarial reaction - evanescent pruritic exanthem on arms and legs and mild angioedema (welts) back of legs.

Swelling, hotness, redness of injection site. In a triangle almost, put Bendaryl gel on it overnight and nothing changed.

chills and aching joints 2 and 3 days after shot. day 5 lymph nodes swelled on the same side of the body as the injection. chills returned.

Noticeable fatigue and two very swollen lymph nodes - one along right collar bone, below neck, and one on right side of neck. The fatigue started the day after the vaccine and lasted for about 4 days. The lymph nodes became swollen 3 days after the vaccine was administered and stayed swollen about one week. They were very sore, even turning the neck hurt, and this lasted for about 4-5 days.

Admission HPI: Right-sided chest pain began 2 days prior to admission (3/19) after getting out of car, without identifiable trigger. Pain was sharp, pleuritic, and worst with movement; didn't feel it when still. Pain not responsive to ibuprofen or heating packs. Reported 30-60 seconds of self-resolving heart racing during ocular migraine which has been his baseline for years. Not associated with SOB (at rest or with exercise), palpitations, presyncope, or syncope. No viral URI symptoms, N/V, or rash. He did receive his 2nd Moderna COVID vaccine about 1 week PTA, followed by 36hrs of fevers, chills, and body aches. Given persistence of pain, Patient asked his parents to present to urgent care. In UC, he was noted to tachycardic with CXR with bibasilar atelectasis and b/l effusions, per report. Given continued tachycardia, decision was made to transfer to ED to r/o PE. In ED, tachycardic to 104-116 and tachypneic 22-26. Had one episode of tachycardia to 182 iso ocular migraine. Endorsed chest pain but points to R middle abdomen when asked where worst. Exam was unremarkable. He received 1 dose of morphine which reduced pain from 10/10 to 0/10. Labs notable for leukocytosis (14.61), thrombocytopenia (422), elevated d-dimer (1.56), and elevated CRP (5.6). Otherwise normal chem and coags. COVID/RVP negative. CXR unremarkable. CTPA showed scattered PEs in b/l lower lobes with small pulmonary infarct in RML. No evidence of right heart strain. Heme was consulted who recommended starting him on lovenox and sending lupus anti-coagulant. Cardiology was consulted who recommended EKG, BNP, and troponin, all of which were normal and reassuring against right heart strain. ECHO was therefore deferred to the AM. The decision was made to admit. Upon arrival to the floor, Patient was tachycardic 114 and tachypneic to 22, otherwise stable vitals. He denied any pain since morphine. Denied any unexpected weight loss; reports that car ride was short. Mom reports that Patient has been less active d/t cold weather and baseball being on hold. Denies family or personal history of clots. Last seizure ~13 years ago. Hospital Course: (3/21 - 3/22) Patient was admitted to the hematology service. He was therapeutically anticoagulated with LMWH injections and his anti-Xa level prior to discharge was 0.92. (goal 0.5-1.0) Lower extremity ultrasound with Doppler showed patent veins and no evidence of DVT and upper extremity ultrasound showed no evidence of DVT, though there was potential evidence of collateralization seen in mid and distal third of right subclavian vein and left internal jugular vein. Since this was an unprovoked PE, a full thrombophilia workup was sent and will be followed up by the outpatient hematology clinic. Cardiology consulted regarding possibility of right heart strain and the tachycardia during migraine episodes. Echocardiogram performed on 3/22 was technically limited but showed no gross abnormalities. The cardiology team requested a repeat echo scheduled outpatient for 1-2 months after discharge.

Angioedema; This literature-non-study case was reported in a literature article and describes the occurrence of ANGIOEDEMA (Angioedema) in a 20-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. LITERATURE REFERENCE: Polyethylene Glycol and Polysorbate Skin Testing in the Evaluation of COVID-19 Vaccine Reactions: Early Report. Annals of Allergy, Asthma & Immunology. 2021 The patient's past medical history included No adverse event (No medical history reported). On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced ANGIOEDEMA (Angioedema) (seriousness criterion medically significant). At the time of the report, ANGIOEDEMA (Angioedema) outcome was unknown. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments. Treatment medication included steroids and antihistamines Very limited information regarding this event/s has been provided at this time. Further information has been requested. Critical details to include patient's medical history, mRNA-1273 administration date and onset date of the event is lacking. No further information is expected. This case was linked to MOD-2021-075562, MOD-2021-075577 (E2B Linked Report). Reporter did not allow further contact; Sender's Comments: Very limited information regarding this event/s has been provided at this time. Further information has been requested. Critical details to include patient's medical history, mRNA-1273 administration date and onset date of the event is lacking. No further information is expected. MOD-2021-075562:Same Literature Article MOD-2021-075577:Same Literature Article

Patient experienced previous DX of Covid 19 symptoms and had supraclavicular lymphadenopathy x3 days.

Admitted 72 hours after 2nd Moderna dose with acute onset chest pain, EKG changes, positive troponin and elevated CRP. Coronary CT ruled out coronary disease. Transthoracic echocardiogram revealed EF 55-60% with inferior wall hypokinesis. Findings on cardiac MRI consistent with acute myopericarditis.

12 minutes after injection - local itching/redness. 30 min. after vaccination anaphylaxis with multiple organ involvement - skin injection site and uvula swelling and eyes itchy. Patient had angioedema of throat with swallowing difficulty. Had mild asthma/wheeze. Also had tachycardia and light headed when trying to sit up. Patient given Epi 0.3 ml IM, Benadryl 50 mg IM, and Pepcid 20 mg PO. Transported to hospital by EMS for 4-6 hour observation. Patient responded well to epi.

30 minutes after vaccination an area of the patient's LEFT elbow began to swell to about the size of an egg. The patient reported the spot felt "like a bruise". The patient was more panicked than in pain. The pharmacist drew a circle around the swollen area with a marker and instructed the patient to go to urgent care to be examined.

severe chest pain on 05/10/2021, labs noted with elevated troponin and elevated CRP, diagnosed and treated for acute

Patient is a 20 y.o. male with no significant past medical history presenting with acute burning retrosternal chest pain and diaphoresis, found to have diffuse concave STE with PR depressions and reciprocal changes in AVR, along with significant troponin elevation (peaked at 8K), c/f STEMI, LHC therefore pursued on 5/13 which revealed clean coronaries. TTE also with pEF and no WMA. Of note, pt recently received 2nd dose of Moderna COVID-19 Vaccine, myopericarditis therefore considered, CRP elevated at 45, subsequently started on high dose ASA + colchicine therapy. CMR also pursued and was noted to be unremarkable. Pt without return of presenting chest pain.

Patient with onset of sharp chest pain 1 day after second vaccination. Patient diagnosed with myopericarditis and admitted to the hospital for further evaluation and management. Patient with improved symptoms, but placed on several medications for continued management of inflammation.

Appointment time was 12:00 pm and one hour later symptoms included rash and pain at the point of injection Redness and swelling in the arm Swelling of lymph node under the armpit Nausea and headache The symptoms and pain has continued as of today Redness and swelling started out as the size of a nickel and is now the size of a closed fist Video and pictures have been taken Will be visiting Dr for further assistance today

2-day history of progressive chest pain, 2 days after receiving his second dose of the Moderna vaccine.

Patient complains of extended experience of pain, swelling, and redness in left unilateral axilla. Pain is significant enough to cause loss of sleep and significant alteration in daily lifestyle. Pain is described as most significant at site of axilla.

Swelling in both feet/ankles, joint pain in both feet/legs, red spots underneath skin in both legs, swelling in left hand

presumptive MIS post vaccine; 2 weeks of headaches, rash, fever to 103, sore throat on 6/26 in ED at hospital platelets 69K; atypical lymphocytoes 0.71; covid PCR neg; ESR 15; CRP 8.6

Development of pleuritic, positional chest discomfort, friction rub on auscultation, ECG with diffuse ST elevations, elevated CRP consistent with a diagnosis of acute pericarditis

He had the vaccine on 05/12/2021. It started at 1 am, he had a pretty normal night, he went to bed and woke up vomiting, that continued through the night, the vomiting continued, he had a head ache, he called me and told me that his stomach really hurt, I told him to check his blood sugar, he also had hot flashes, chills, and body aches, but mainly he had vomiting, then the next day 5/14/2021 he was getting more sleepy and less responsive, his friends tried to give him water and different things, his blood sugar went up, his friends took him that afternoon to the ER because he started not responding to me, his friends would tell me he was sleeping, so they took him to the ER, they found that he was very dehydrated, they were giving him fluids and did blood work, he was very unresponsive when he arrived, he could not answer his questions, he had a friend that was there that told them he had the vaccine, the blood work said he had a very high white blood cell count they were worried he had sepsis, they found his kidneys were not working ok, because his levels were very crazy and chest pain and severe stomach pain, and he had pancreatitis, they ruled out a heart attack, he then was admitted because he was in DKA, diabetic keto acidosis, like a result of his type 1 diabetes that got flared up because of all his reactions. They admitted him to the ICU and he was there until 05/16/2021 and basically they were just giving him fluids, potassium and other things to help his body calm down and stabilize his blood sugar. He was released and he still continues that his heart hurts but doctors say that these things resolve after a while.

After both vaccinations for COVID-19 (Moderna: First dose - 4/15/2021, Second dose (05/18/2021, I experienced swollen lymph nodes in my armpit and collarbone on the vaccinated side of my body (Right side). Swelling of lymph nodes occurred around 18-24hrs after the vaccination and remained for about 5-7 days. This swelling resulted in varying levels of discomfort (worse in the days shortly after vaccination) when engaging the muscles and tendons around my armpit, feeling like the lymph node was being ?pulled?. Around 2 months after second vaccination (today), there is no pain or discomfort, but I can still feel the lymph node in my right armpit versus being unable to in my left armpit.

Sore arm after injection about 12 hours after that lasted a full day or longer. Severe headaches and migraines approximately 2 days after injection. 5-6 Days after vaccine developed swollen lymph nodes in right arm pit and intermitten pain to move arm that lasted for 2-3 days.

Immediate severe headache (12/30/20). Following day (12/31/20) persisting headache, marked diarrhea, severe chills. Went to local ER: HR 135, afebrile. WBC 12.3 w/10.4 neuts. Chem profile, EKG, UA, CXR all okay. Better with IV's. Advised not to have second dose. Doing well now.

Patient experienced a generalized seizure lasting at least two minutes on Jan. 14th, having received the vaccine on Jan. 6th. Patient has no history of seizure disorder. Patient was taken to the ER per his physician's order. CT scan, x-ray and blood work were unremarkable except for an elevated whilte blood cell count. Patient was released and convalesced at home. There has been no further seizure activity. Patient did not recieve the second dose of the COVID19 vaccine.

"Moderna" Adverse vaccine reaction possible as began 12 hours post second COVID vaccine dose on Friday. A ER note was generated in a T-Con on a patient who got their 2nd Covid Vaccine and began experiencing chest pain approx. 12 hours post vaccine. Patient did not report to the ER until 28Feb21. It was discussed that he has myocarditis v pericarditis, elevated D-Dimer of 770, swollen lymph nodes, and elevated Troponin. Patient was transferred to Research Medical Center due to no available beds. Patient was referred to a Case Manager and Cardiology. The patient completed a follow up appointment with 509 MDG on 9Mar21 and reported Dull pain that has been affecting sleep. Cardiology reports shows Troponin was elevated to 9.1 decreased to 4.2 and back up again to 13.4. Cardiac revealed late gadolinium enhancement, possibly representing myocarditis and then at discharge possibly myocarditis.

Blood pressure and heart rate sky rocketed immediately after shot-did not come down and after an hour went to the ER- was in the ER for 8 hours with continued symptoms. This is a young man with no precious hx of this. Hospital would not entertain the idea this was related to the vaccine. Was discharged with instructions to return if worse in the AM. Continued high blood pressure and heart rate for another 24 hrs. Swollen lymph nodes by the next day. Blood work in hospital showed immune response happening but again hospital would not attribute to vaccine.

Patient presented to ED with chest pain 10/10 at about 16:48 . Aspirin 324 mg chewed at 17:51. Stat EKG done, STEMI discovered, patient went to cath lab for intervention at 17:20. No recreational drug usage noted. Patient admitted to ICU following procedure for continuing care.

Patient developed acute onset of hives on face and body and reported facial swelling and difficulty breathing approximately 8 days after receiving first Covid shot. Stated this occurred approx. 11:40pm 3/26/21. Patient arrived at ER 1:10am on 3/27/21 where facial swelling and rash on perioral area, upper back & proximal arms was confirmed. He was given prednisone 60mg, diphenhydramine 50mg & famotidine 20mg. Home RXs for diphenhydramine 50mg po q6h prn, famotidine 20mg po bid & prednisone 40mg po qd provided. He was discharged at 02:48. Patient now recovered but will not receive second dose of Covid vaccine. *NOTE: patient stated grandmother had similar reaction to Covid vaccination which occurred one week after shot.

Patient presents to ER with chest pain, worse with deep inspiration, lying flat or leaning forward. Pain is better when sitting up straight. Vomiting x 1 episode. First Moderna shot on 4/9/21. Chest pain started on 4/11/21. On 4/14/21, pain was worse, so came to ER. Patient admitted to hospital, cardiology consult, pulmonology consult. Patient is treated with colchicine 0.6mg twice daily, NSAID and metoprolol 25mg twice daily. Follow up with cards in 2 weeks. Much improved on day 2.

21 yo male had the Moderna vaccine 1.5 weeks ago and 3 days ago he was lifting light and last hs he got pain and swelling to the left upper back above the scapula. He has 10/10 pain. he has been icing it. He did not lift heavy when working out and did not feel a pull or twinge. It was his first vaccine in the series. Physical exam: He has 4 cm area of tenderness and swelling to the left upper back, above the scapula. Pain with abduction of the left arm. No pain in shoulder joint or swelling.

I?ve started getting a full body rash. The rash is pretty itchy with some minor swelling but not that bad overall. It?s not at all in my right arm where I got the shot, or in my left arm for that manner. It seems to be nearly entirely concentrated in my stomach region and especially my hands which are somewhat swollen. This reaction is pretty similar to my Penicillin reaction albeit significantly stronger.

Moderna COVID-19 Vaccine EUA. Injection site pain lasted for 3 days. No symptoms for the next 3 days. On the 6th day after the shot, swollen armpit/armpit pain started. Not severe enough to justify seeking medical help. Lapse in arm pain to armpit pain was surprising.

This is a very pleasant and healthy 21-year-old with history of migraines with aura who presents to the ER 2 days after receiving his second Materna vaccine with complaint of chest pain, myalgias and fatigue. Patient reports normal postvaccination myalgias and fatigue for the last 2 days but had onset of left-sided chest pain that radiates to his upper back and is worse with deep inspiration, some positions and movement of his left upper extremity. He denies cough, shortness of breath or rash. He is low risk for pulmonary embolism with PERC score negative for PE. Screening EKG showed a sinus rhythm with elevated J point in anterior-lateral leads, ? ST elevation in 1 and AVL w questionable reciprocal changes in leads 3 and AVF. Patient went to CXR. Clinically very low risk patient for STEMI from CAD. ? Myocarditis or pericarditis? No hx of stimulant use or early CAD in family. Upon reevaluating the patient, clinically he seems to have musculoskeletal chest discomfort, worse with palpation and movement of LUE. Repeated EKG - showed more definative ST elevation through anterior and lateral leads with reciprocal changes in 2, 3, AVF. Slight ST elevation in AVL. ? Pericarditis vs myocarditis. Will call cardiac alert. Evolving EKG changes. Discussed with ED physician and Interventional Cardiology, we agreed, patient likely has acute myocarditis clinically. Very low risk for CAD. Gave aspirin and heparin. They will evaluate him. Labs coming back... wbc 17.4, normal chemistry. Sending off CRP, ESR. Troponin pending. Patient and family appreciative and understanding. 1710 - Follow up call from cardiology. Stat echo normal wall motion. With elevated CRP and mild trop 1.6, patient has myocarditis with pericarditis. Dr very appreciative for the detailed history and physical. CP free. Holding off on cath lab.

Extreme swelling of lymph node in arm of injection site. Armpit lymph node is approximately the size of two marbles

Two days after administration of first COVID-19 vaccination, patient developed blood streaked diarrhea and abdominal pain. Patient was referred to emergency room, prescribed Lomotil, workup for IBD. History of poor weight gain, C.diff infection 2 years ago (2019). Patient referred to GI for further work up.

received Moderna COVID-19 vaccine on 6/28 and since 6/29 has had worsening chest pain with shortness of breath, but it was most notable yesterday. He went to urgent care , and had an EKG, with the results being abnormal. He reports it feels better when laying down and is exertional. He had chills, abdominal pain and myalgias, headache.. impression is myocarditis likely related to the vaccine.

presented to the emergency room with symptoms of chest pain. He received Moderna covid vaccine on Tuesday and since then he has been having symptoms of myalgias and chest pain. He mentions that the chest pain is substernal, gets worse with deep breaths. It gets worse when he lays on his back. And feels better when he sits up. He also had subjective fevers. When he presented to the emergency room he was having crushing chest discomfort with a troponin level at 10 and was referred for an emergent coronary angiography with concerns for acute coronary syndrome. Diagnosis/Impression: Acute myocarditis after Covid vaccination: Based on positional changes and pleuritic nature of the chest pain. Given troponin level left hand and ongoing crushing chest discomfort he was emergently taken to the Cath Lab where he does not have any significant coronary artery disease or thrombotic occlusions. LV gram shows hyperdynamic LV systolic function. At this time his symptoms are consistent with myocarditis.

He reports that the same evening of the vaccine he noticed arm swelling, pain at the site and generalized body aches. He also reports that his tongue and throat felt numb for four hours. He also noticed a little cough, shortness of breath and a runny/stuffy nose.

Raised hives since 1/22. Has been all over my body. My hands were completely swollen and couldn?t make a fist in 2/2. The hives/rash has been most commonly found on my arms and thighs, and also my calves and buttocks.

Patient reported swelling at the injection site, lymph node within the neck swelling, and pain at the injection site.

Extremely sore and swollen shoulder the day after, 3/25/21. 8 out of 10 on personal pain scale. Took ibuprofen to relieve pain. As of 3/26/21, swelling has gone down and pain has reduced to a 3 out of 10 on a personal pain scale.

Lymph node in injection arm swollen and painful. Dull ache present in entire arm. Began two days after injection, became significantly more unpleasant on day 7. It is still day 7 at the time of this writing.

"Moderna Arm"; Localized red rash near injection site that appeared around 7 days after injection. Warm to the touch but little to no itching. Slight underarm lymph node tenderness. Rash approximately 1 inch in diameter.

Patient had his 1st dose of the Moderna vaccine & developed commonly reported side effects, sore arm & fatigue shortly after the vaccine was administered. As the week continued past 48 hours post injection period, he was experiencing extreme fatigue & muscle aches. On the morning of 3/29 his feet were tingling & his legs were stiff. When he woke up on 3/30 the stiffness in his legs & the tingling increased to the point where walking became difficult. Finally on the morning of 3/31 he could not walk without assistance. His PCP said to take him to the emergency room. Patient was admitted to Medical Center with the suspicion of Guillain Barre Syndrome. A lumbar puncture confirmed Guillain Barre on 4/1/21 and a 5 day course of IVIG was started immediately after confirmation of diagnosis.

Chills for 2-3 hours of duration following 5 hours after vaccination, nausea, The following morning: 10/10 non-radiating chest pain of pleuritic feeling, tingling in limbs, syncope, SOB Tachycardia(108 bpm)

pt developed peri rectal abscess 4/1 requiring inpatient management due to sepsis and I&D also noted to have incidental finding of pseudocyst pt has no h/o etoh use or any abd pain or diarrhea has had abd cramps on and off in the past will be getting referred to GI for IBD work up

Systemic: Dizziness / Lightheadness-Medium, Systemic: Fainting / Unresponsive-Medium, Additional Details: Patient felt dizzy/light-headed within 1-2 minutes of receiving his 2nd dose of Moderna vaccine on 4/18/21 at ~12:30pm. Patient stood up from the waiting area, walked approximately 20 feet to the pharmacy window to request assistance where he fainted and hit his head on the counter ledge. He has a raised bump (approximately 2 inches wide) on his right temple above his eyebrow. Patient remained conscious, received water/juice/granola bar & was monitored by the RPh for an additional 30-40 minutes.

Developed fatigue, back pain, chest pain, nausea and vomiting the morning after the vaccination. On Saturday 4/17, I awoke feeling some better. Performed my daily routines uneventfully other than just not feeling 100 percent. By that evening the chest pain returned. On 4/18, I awoke with severe chest pains. I then presented to the ER where was presumed I was having a heart attack vs. acute pericarditis/myocarditis.

* Tuesday, March 16th, I received my first Moderna shot. No immediate symptoms, felt fine. * Thursday, March 25th (9 days post-vaccination), I was sitting at my desk and experienced some kind of visual distortion (my computer monitor bounced up and down 4 times in quick succession, even though I was perfectly still). Got up from my desk and laid down, and it went away. * Tuesday, March 30th (two weeks post-vaccination), I started experiencing persistent dizziness/imbalance. It was manageable for the first couple of days, and I still went about my daily activities. * Thursday, April 1st, symptoms got noticeably worse. I had a really bad episode of vertigo/dizziness in the afternoon. This spell of bad symptoms lasted until Saturday evening/Sunday morning. I wasn?t falling down, but I would describe it as akin to being on a boat in rough seas or a plane flying through a storm. Pressure in head and ears was intense. I?ve had longstanding tinnitus, but pitch/volume definitely seemed to change somewhat. My neck was incredibly stiff, and my throat felt somewhat ?tight? (tonsils or lymph nodes in neck felt enlarged). Took ibuprofen and Benadryl on and off over next several days. * Tuesday, April 27th, symptoms are ongoing. Still having imbalance, dizziness, and non-spinning vertigo, though less severe than previously.

Patient presented to the ED and was subsequently hospitalized within 6 weeks of receiving COVID vaccination. Diagnoses include: severe sepsis, pneumonia, toxic shock, and myocarditis.

Patient is 22 year-old, admitted to the Cardiology 3 Emergency Department with acute myocarditis shortly following the receipt of his 2nd Moderna COVID-19 vaccination. He has a remote history of acute pericarditis (01/12/2014) following viral illness, which was treated with high dose ibuprofen 800 mg t.i.d. At that time, he presented with retrosternal chest pain worse with laying down and fever/myalgia, rigors and chills (T 103.3°F) with laboratory findings consistent with leukocytosis 17.3, elevated inflammatory markers (CRP 43, but normal ESR 12) with a negative influenza screen. ECG demonstrated diffuse ST wave elevations in leads I, II, aVF, V1-V6. He had resolution of symptoms with NSAID treatment. On this occasion, he presented with non-radiating retrosternal chest pain not responding to Ibuprofen 800 mg. At the ED, ECG demonstrated diffuse ST elevation, troponinemia 629/725/712/1319, elevated inflammatory markers (CRP 38.2, ESR 19). He had normal D-dimer and SARS-CoV-2 PCR was undetected. A cardiac MRI was obtained that demonstrated patchy subepicardial enhancement in the mid-apical lateral-anterolateral myocardium, suggestive of myocarditis. EKG showed diffuse ST elevation. He was treated with Toradol and fentanyl for pain management with improvement of symptoms. He was then admitted to Cardiology 3 for further evaluation and management. Upon admission, Infectious Disease was consulted given the novelty of his presenting symptoms and findings. Extensive evaluation including connective tissue cascade, respiratory viral panel and tick bone panel have not yielded any significant findings. They suspected this could be related to his recent COVID vaccine given that there have been reports of myocarditis that have occurred following COVID-19 messenger RNA vaccinations, though it is not clear whether there is a definite cause or effect. Moreover, the association of myocarditis and the messenger RNA COVID-19 vaccinations appears to be controversial, not supported by recent FDA reports. All in all, the Infectious Disease team recommended no specific therapies, but the case should be reported as a possible adverse event associated with the recent Moderna vaccination to VAERS. The center where the patient received this vaccination should make this report. Emergency Management Director was notified to report the event. They also felt that it may be reasonable to avoid the Moderna and perhaps even the Pfizer messenger RNA COVID-19 vaccination in the future to be conservative. While inpatient, his troponin level continued to trend up and peaked at 1707. An EKG was repeated and showed improvement in ST elevation from his initial EKG with no other acute changes. His case was discussed with Dr., who felt that a steroid taper would be appropriate. Additional chest pain was treated with PRN Ibuprofen 600 mg QID. After initiation of steroids, troponin markedly improved to 706. Due to his history of impaired fasting glucose, his blood glucose levels were monitored q.i.d. While slightly elevated, he did not require any sliding scale insulin while inpatient. We will plan to have his primary care provider assess his glucose level at his follow-up visit. Additionally, while receiving NSAIDs and steroids, his blood pressure was elevated to the 150s to 160 systolic. He was initiated on Coreg prior to dismissal. He was dismissed on 04/29/2021 given improving troponin and no concerning arrhythmias on continuous telemetry monitoring. He will follow up in the Cardiomyopathy Clinic in 3 months with a repeat cardiac MRI and stress ECG. We have recommended the patient to avoid heavy lifting or strenuous activity for the next 3 months until seen by the cardiomyopathy Clinic. He was provided with education and a letter delineating work restrictions.

Very serious aches and pains in my joints. Fever, sore throat, pain in arm. Swollen glands and stiff joints. All started around 9 Pm

Site: Pain at Injection Site-Severe, Site: Redness at Injection Site-Severe, Site: Swelling at Injection Site-Severe, Systemic: Lymph Node Swelling-Severe, Additional Details: patient complaint of soreness/redness and extreme swelling in lymph node and trap muscle on arm.

sudden hearing loss requiring hear aids, ear canal swelling and itching, axillary gland enlargement and pain

CHIEF COMPLAINT & HPI: 22-year-old male here with left shoulder pain at the site of his second moderna vaccine which he received yesterday. patient with subjective fevers and chills. no redness or swelling. Also some axillary lymphadenopathy. No numbness or weakness.

1st Shot(5/3/21): Soreness in arm, Fatique 2nd shot(5/31/21): Soreness in arm, Fatique, headaches, developed a cough a week later which lasted about a week. Adverse event (7/6/21): Started coughing and spitting blood around 5:00pm. Coughing persisted throughout the evening. At 6:00am I told my mom I was having a problem. around 6:30am my body went numb, loud ringing in my ears, and broke out into a cold sweat, so we called 911. The paramedics arrived and checked me out, and they believed I was okay. When they left we decided to go to the ER. Admitted on 7/7/21-7/12/21

Patient reports receiving Moderna vaccine 6 days ago. Felt fine for first 30 minutes following vaccine, but developed migraine headache next day, which resolved after 24 hours. Reports developing pruritic urticarial rash and swelling to hands and feet yesterday. Denies facial or mouth swelling. No chest tightness, wheezing or SOB. Denies previous reaction to vaccines. NKDA. Took benadyl yesterday and today, which did help. Assessment and Plan: 1. Urticaria - Possible correlation to Moderna COVID-19 vaccine received 6 days ago. Will treat with antihistamines and topical steroid cream. Avoiding systemic steroids, as do not want to suppress immune response to recent COVID-19 vaccine. - Treatment with antihistamine- Benadryl OTC and Claritin. - Provided patient with V-safe smartphone tool info to report potential side effects of COVID-19 vaccine. - Completed VAERS report for potential reaction. - Advised employee patient also follow-up with occupational health regarding plans for second vaccine dose. - Follow up at ED if facial swelling, SOB or if symptoms worsen. - Will route chart to PCP. - TRIAMCINOLONE ACETONIDE 0.1 % TOPICAL CREAM APRN.CNP  

Pt reported to clinic for 1x left axillary lymph node enlargement secondary to COVID-19 vaccination, pain 7/10 and swelling the size of a ping pong ball. No anaphylaxis. Pt reported to clinic on 20 Jan 2021, 5 days after swelling presented.

Lymphadinopathy in Left armpit 4 days following vaccination. Pt reported to Medical 2 days after noticing adverse event. Pt given Ibuprofen, told to apply RICE & told to return if symptoms do not resolve.

Service member received Moderna Vaccine Dose 1 on 01 FEB 2021. Service member experienced skin irritation, redness, and hives within an hour of receiving the vaccine. After going back to work, SM's symptoms worsened with itchiness and throat soreness. Symptoms progressed at home and noticed hives all over body and swelling around the face. Patient saw a provider in Clinic. He was prescribed Prednisone and Zyrtec which provided relief and symptoms improved and were mostly gone by Day 4. Instructed by his commander and provider to refrain from getting second dose of the vaccine.

A couple of hours after my fist dose Moderna vaccine, my left arm began to hurt, I also developed headaches, body aches and left arm swelling. At 1am-2am, I could not move my left arm and my fever was 103.3F. I contacted urgent care who told me to take Ibuprofen as pain medication. My symptoms did decrease although I still have today difficulty sleeping and sweat at night which I did not have before the vaccine.

2nd vaccine administered 4/17 and on 4/19/21 he started to have chest pain not relieved by Tylenol and presented to ER with high Troponin.

Received vaccinastion on Monday 19Apr21. Swollen subdivicular lymph and axillary lymph nodes swollen 23Apr21. Spike in pain (5/10) and admittance to ER 26Apr21.

After 2nd dose (May 3rd)...May 6th started to notice swelling in top half of both hands, stomach and chest developed hives and a rash. Not very bothersome, hands are very warm and extremely inflamed. Took allergy medications, they haven't done anything. No reactions after 1st dose, this is all after 2nd dose.

23 yo man in high school when standing, admitted wit acute onset epigastric abdominal pain after a run, found to have mild elevation in troponin, flat at 0.04, dynamic EKG changes admitted or work-up 1. Acute epigastric abdominal pain/elevated troponin: The patient was chest pain free from the time of treatment with Pepcid, magic mouthwash, and Toradol in ED. His echo is without wall motion abnormalities, troponin is flat and remains chest pain free. The patient had a CT PE protocol study and CTA coronary without acute findings. He had a cardiac MRI which showed no acute myocarditis but may have had some delayed contrast enhancement and may represent prior myocarditis. He was started on low dose lisinopril 2.5 mg po daily for cardio-protection, will reduce physical activity with slow return to activity, and follow with cardiology with an urgent exercise stress test as an outpatient. His u tox shows cannabinoids and no other intoxicants, His lipid panel wnl, HDL 65, LDL 84, His TSH is wnl. His CRP and ESR is wnl. 2. Left axillary lymphadenopathy: Discussed with patient lymph nodes seen on CT scan in left axilla and left pectoral region. Patient cofnirmed he had a COVID 19 Moderna vaccine in the left arm on 4/3/2021. Epic documentation notes in the right axilla, but patient is clear that he had the vaccine in the left arm. Axillary lymphadenopathy is not surprising in this situation. 3. Small 4 mm nodules noted on CT scan: The patient had no infectious symptoms, no cough, no fever, and no elevated WBC. He does smoke marijuana but has no tobacco use. He can follow with PCP to further risk stratify the nodules, either with PPD, and consideration of repeat scan in 6-12 months as needed. 4. Mild bilateral gynecomastia: I informed patient this has been found. He is not bothered by this finding and it seems an incidental finding. He can follow with his PCP for further evaluation as needed for this finding. Inpatient Consultants and summary of recommendations: 1. Seen by Cardiology and CTA coronary followed by MRI and then plan for outpatient exercise stress test planned Discharge vitals: Temp: [97.4 °F (36.3 °C)-98.7 °F (37.1 °C)] 97.4 °F (36.3 °C) Pulse: [55-65] 65 Resp: [16-18] 17 BP: (108-114)/(61-72) 111/61 SpO2: [96 %-100 %] 99 % Device (Oxygen Therapy): room air Pertinent Findings of Physical Exam: as noted in exam Cognitive Status at Discharge: Baseline Alert and Oriented x 3 Discharge Physical Exam: Physical Exam Constitutional: He is oriented to person, place, and time. No distress. Cardiovascular: Normal rate, regular rhythm and normal heart sounds. Abdominal: Soft. Bowel sounds are normal. He exhibits no distension. There is no abdominal tenderness. There is no rebound and no guarding. Musculoskeletal: Normal range of motion. General: No edema. Neurological: He is alert and oriented to person, place, and time. Skin: He is not diaphoretic. Nursing note and vitals reviewed. Allergies No Known Allergies PMH PSH Past Medical History No past medical history on file. Past Surgical History No past surgical history on file. Social History Family History Social History Tobacco Use ? Smoking status: Never Smoker ? Smokeless tobacco: Never Used Substance Use Topics ? Alcohol use: Not on file No family history on file. Discharge Medications: Discharge: Current Discharge Medication List START taking these medications Details calcium carbonate (TUMS) 500 mg (200 mg calcium) chewable tablet Take 1 tablet (500 mg total) by mouth daily. Qty: 14 tablet, Refills: 0 Start date: 4/18/2021, End date: 5/2/2021 lisinopriL (PRINIVIL,ZESTRIL) 2.5 mg tablet Take 1 tablet (2.5 mg total) by mouth daily. Qty: 30 tablet, Refills: 0 Start date: 4/20/2021 CONTINUE these medications which have NOT CHANGED Details emtricitabine-tenofovir, TDF, (TRUVADA) 200-300 mg tablet Take 1 tablet by mouth daily. Qty: 30 tablet, Refills: 0 Associated Diagnoses: Need for prophylaxis against sexually transmitted diseases clindamycin-benzoyl peroxide (BENZACLIN) 1-5 % gel Apply topically 2 (two) times daily. Qty: 25 g, Refills: 2 Associated Diagnoses: Folliculitis clindamycin-benzoyl peroxide (DUAC) gel

Arm soreness/aches started about 6hrs in (though injection sight was tender/sensitive to the touch pain became mostly localized around the armpit and shoulder area. Where the pectoral connects under the arm), then around 8hrs a headache and chills started. Chills and headache progressed and got significantly worse throughout the night. By around18hrs headache had progressed to a migraine and nausea started (likely due to the migraine). Simply sitting up in bed was enough to push nausea to vomiting at which the migraine subsided for about 30min-1hr. Chills and aching arm persisted. By 24hrs headache/migraine was nearly completely gone and chills had subsided. Arm pain persisted and got worse. Noticed around this time that there seemed to be mild swelling in the armpit. Around 48hrs in armpit area is still feels slightly swollen and causes a good bit a pain depending on how arm moves/rests. Injection sight still lightly tender. (currently the only symptom persisting)

Same day fever associated with chest pain that was positional. Admitted to the hospital, diagnosed with Myopericarditis based on elevated troponin, CRP, clinical history, and cardiac MRI.

The vaccine is affecting young people; My son felt like he had an aneurysm in his neck/He had pain in the large artery on the right side of his neck like a myocardial inflammation or something; The right side of his neck, between the shoulder and neck, on the inside, he felt swelling, pressure pain, dull pain that comes and goes; On Tuesday, on the right side of his neck, between the shoulder and neck, on the inside, he felt swelling, pressure pain, dull pain that comes and goes; shoulder pain; On Saturday night he was feeling tired and cold; feeling cold; On Saturday his legs were very heavy and had pain, like he had blood clots or thrombosis in his veins; On Saturday his legs were very heavy and had pain; This spontaneous case was reported by a patient and describes the occurrence of THROMBOSIS (On Saturday his legs were very heavy and had pain, like he had blood clots or thrombosis in his veins) and ANEURYSM (My son felt like he had an aneurysm in his neck/He had pain in the large artery on the right side of his neck like a myocardial inflammation or something) in a 23-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 027L21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. Concomitant products included BUPROPION HYDROCHLORIDE (ZYBAN) for an unknown indication. On 21-May-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 22-May-2021, the patient experienced THROMBOSIS (On Saturday his legs were very heavy and had pain, like he had blood clots or thrombosis in his veins) (seriousness criterion medically significant), PAIN IN EXTREMITY (On Saturday his legs were very heavy and had pain), FEELING COLD (feeling cold) and FATIGUE (On Saturday night he was feeling tired and cold). On 25-May-2021, the patient experienced ANEURYSM (My son felt like he had an aneurysm in his neck/He had pain in the large artery on the right side of his neck like a myocardial inflammation or something) (seriousness criterion medically significant), NECK PAIN (The right side of his neck, between the shoulder and neck, on the inside, he felt swelling, pressure pain, dull pain that comes and goes), SWELLING (On Tuesday, on the right side of his neck, between the shoulder and neck, on the inside, he felt swelling, pressure pain, dull pain that comes and goes) and ARTHRALGIA (shoulder pain). On an unknown date, the patient experienced VACCINATION COMPLICATION (The vaccine is affecting young people). At the time of the report, THROMBOSIS (On Saturday his legs were very heavy and had pain, like he had blood clots or thrombosis in his veins), ANEURYSM (My son felt like he had an aneurysm in his neck/He had pain in the large artery on the right side of his neck like a myocardial inflammation or something), VACCINATION COMPLICATION (The vaccine is affecting young people), PAIN IN EXTREMITY (On Saturday his legs were very heavy and had pain), NECK PAIN (The right side of his neck, between the shoulder and neck, on the inside, he felt swelling, pressure pain, dull pain that comes and goes), SWELLING (On Tuesday, on the right side of his neck, between the shoulder and neck, on the inside, he felt swelling, pressure pain, dull pain that comes and goes), FEELING COLD (feeling cold), ARTHRALGIA (shoulder pain) and FATIGUE (On Saturday night he was feeling tired and cold) outcome was unknown. No treatment information was provided. Company comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. This case was linked to MOD-2021-182543 (Patient Link).; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

Myocarditis with troponin I HS 31,561, wall motion abnormalities, LV dysfunction, Improved with high dose IV steroid.

Systemic: Joint Pain-Severe, Systemic: Lymph Node Swelling-Severe, Additional Details: PATIENT'S MOM CAME TO THE PHARMACY AND REPORTED THAT PATIENT WOKE UP THE NEXT DAY WITH A SWELLING PAINFUL LEFF ANGKLE. PATIENT EVEN CAN NOT WALK. NO PAIN OR BRUISING AT THE INJECTION SITE

high fevers (104-105) several weeks after vaccine with negative infectious work-up. Also with anterior cervical lymphadenopathy and cracked lips. I am concerned for Kawasaki disease flare-up although did not have all typical features of this disease

I am reporting a strange bump underneath my collarbone, possible enlarged lymph node Reported bump is moveable, slightly firm, but not hard bump only appears on left side, underneath the collarbone, not found on the other side Bump is not painful, or tender Bump is roughly the size of a pinky

Left Axillary pain and mild swelling starting approximately 4 days after vaccination. The pain proceeded to worsen over the next week and moderate lymphadenopathy was also been noted. These lymph nodes are tender to palpation. Additionally some Parasthesias were felt down the left forearm into the hand possibly due to brachial neuritis or nerve pressure due to lymphadenopathy. The parasthesias lasted approximately 2 days. Lymphadenopathy is now present in the right axilla along with more severe adenopathy in the left axilla. - PA-S2

I had the normal sore arm. I ended up the next day with stuffy nose, sore throat, tired, weak. The next day I had the post nasal drip and really fatigue and my sugars were running high, cough and swollen glands. The third day I went to the Doctor to get Covid test, it was negative. The Dr. said I had a chest infections, post nasal drip. It took about two weeks to go away, they didn't want to give me any medication because they didn't know about the shot. I had two Covid test and they were negative.

01/21/2021 11:22am HCP #2 Triage for COVID 19 SEVERE post Vaccine Reaction VAERS reportable Contact #: Your concerns: Dept: Have you missed work? #shifts: today Did you seek emergency care? yes Date and Time of Vaccine: 1/20/2021 @ Age at time of vaccination, ____24____ years Sex: m Was the vaccine received at facility? yes Site of vaccine (LD or RD): LD Type of Vaccine Pfizer ( X) Moderna ( ) Other _______________ 1st or 2nd dose: 2nd When did your symptoms start? 1/20/2021 Please note reported symptoms yes or no, these symptoms are considered mild to moderate and are NOT VAERS reportable Injection site pain yes Tiredness yes Headache yes Muscle Pain yes Chills yes Joint Pain yes Fever (note temp if known) no Injection Site Swelling no Injection Site Redness no Nausea no Feeling Unwell yes Swollen Lymph Nodes (lymphadenopathy) no Other: Patient reports THE FOLLOWING SEVERE post vaccine ADVERSE reactions (reportable): Difficulty breathing no Swelling of your face and throat swelling of the lower lip A fast heartbeat relates heart rate greater than 110 A bad rash all over your body no Dizziness and weakness If COVID-19 symptoms persist and/or worsen beyond 48 hours consider COVID-19 testing Treatment/Advise: Plan: Consulted with HCP, patient sent to urgent care clinic for further evaluation. If patient was vaccinated at another facility, they need to contact that facility , it is an expectation that the facility that gave the vaccine complete the VAERS report. Patient verbalizes understanding and agreement with plan. VAERS report is completed electronically if vaccine given at facility. Signed by HCP on 1/21/2021 at 11:22am

Patient states a painful rash developed in the eft axilla accompanied by a single hard nodule about the size of a quarter 24 hrs post vaccination. I saw the patient on day two. Noted multiple flat erythemic rash at the left axillary pocket there is no palpable nodule but site is tender to touch. There is also a single flat discrete erythemic plaque located along the mid axillary line, right next to the serratus muscle. Vital sign is stable, member is afebrile, ROM is not affected. Member advised to take Tylenol for treatment of pain

24y/o male with remote history of Kawasaki disease fevers, chills, night sweats, anorexia, nausea, vomiting, dehydration, chest pain, dyspnea, constipation. Symptoms began around 1600 on 27JAN21 (day of immunization). Worsened on 28JAN21. On 29JAN21 presented to primary care with tachycardia prompting IV fluid resuscitation.

Left arm and hand swelling within 15 minutes after first vaccine. Later that evening his left left was swollen also on the same side that he received his vaccine. 2-3 days his injection site was sore.

I did not feel anything shortly after the injection, but later in the evening, started to develop a normal post-vaccine soreness. I thought little of it and went to bed. I woke up just after 3am with chills, fever, and worsened arm pain, to the point that it restricted my arm's range of motion and speed of motion. Interestingly, the arm is not red or swollen, but is painful near the injection site, and the area around my clavicle on that side is somewhat swollen, but not red or painful (likely a lymph node). I was unable to get back to sleep due to these side effects (primarily chills and fever). After a few hours of trying to get back to sleep, I took some Tylenol and tried to eat breakfast. I was unable to keep much down, and had to arrange a day off of my internship, and was finally able to sleep on and off for the next few hours. The symptoms have somewhat lessened, but have not resolved, after about 22.5 hours post-injection. I fully expect this to resolve or mostly resolve by the 48 hour mark. I mostly found this unusual due to the severity of the reaction and after only the first dose, and wondered if my young age could have something to do with the clearly robust immune response so soon after inoculation.

Painful swollen lymph node in left armpit. Tenderness in left pectoral. Onset was approximately 5 days after vaccination.

Patient was given dose one of Moderna vaccine this morning. Patient returned to our site around 1230 pm with ?facial swelling.? He also reported throat itching and tightness.

Swelling in both armpits, and tenderness in both the armpits and the groin began the day after the 2nd dose of the Moderna Vaccine, lasted for several days, then subsided. Approx three weeks later, the same symptoms came back, but with less severity.

Lymph node developed on left collar bone and have yet to see a doctor about it. It can be move around slightly and doesn't hurt or cause much discomfort.

Severe rash on toes, feet, legs, mouth, hands, and upper arms. Swelling in feet and toes. Injection site has become very hot to touch. Rashes began on 04/03/2021 on just the back of heels but then spread quickly to top of feet and toes within just a few hours. Used diphenhydramine gel and cream on feet on the night of 04/03 to be able to sleep. Rash on injection site and on the same region of opposite arm intensified on 04/04/2021. Intense itchiness called for more ointment on both upper arms injection site still hot to touch and ring rash has become more visible. Foot and toe rash returned at 8 pm 04/04/2021 and is unrelenting. Bumps appearing on toes.

Day after receiving vaccine, patient notes progressive leg swelling, facial puffiness, and feeling of neck fullness. He estimates he has gained about 20 pounds. On 4/11, he was seen at an emergency room and diagnosed with new onset nephrotic syndrome.

Face started swelling and full body hives. Face is still swollen next morning, hives have gone away though.

11am - sore arm 7pm - chills/fever & chest pain 8pm - increased chest pain 4/18 1pm - increased chest pain, fatigue, chills 11pm - unbearable chest pain 4/19 7am - leave for Emergency Room. Go from ER to Hospital. Diagnosed with Myocarditis.

patient describes facial swelling for several days after vaccine administration, a diffuse rash that has mostly resolved on arms and trunk of body , and persistent joint pain to the shoulders, hips, and knees

Diagnosis: acute pericarditis and acute myocarditis. Patient received Moderna Covid19 vaccine 1st dose 4/21/2021 LOT 037A21B to left arm. Stated he had sore arm. Patient received Moderna Covid19 vaccine 2nd dose on Tuesday, 5/25/2021 LOT 044B21A to right arm. Tuesday afternoon he developed a fever but did not take his temperature. On Thursday morning (May 27) he was at rest and stated that's when he first felt chest pressure. Chest pain got worse since yesterday, prompting a visit to urgent care then urgent care sent patient to ED. Denies shortness of breath, dizziness, cough, or other associated symptoms. complains of anterior chest pain, does not radiate. non smoker. trop 3.79, CRP 35.4; sed rate 17, EKG . ED physician consulted with cardiologist. Patient given ibuprofen 600 mg PO x1 in ED and discharged on ibuprofen and will be following up with cardiologist. discharge dx by ED doc: acute pericarditis and acute myocarditis

Sore throat, cough, congestion since Tuesday after receiving Moderna #1 vaccine; states cough got worse with increased green mucous; no meds today

Site: Redness at Injection Site-Mild, Site: Swelling at Injection Site-Mild, Systemic: Allergic: Swelling of Face / Eyes / Mouth / Tongue-Mild, Systemic: Dizziness / Lightheadness-Severe, Systemic: Fainting / Unresponsive-Severe, Systemic: Flushed / Sweating-Medium, Systemic: Visual Changes/Disturbances-Medium

Ascending paralysis with lesions found on MRI in the spinal cord. Suspicious of neuromyelitis optica. One month after completion of the MODERNA COVID-19 vaccine.

6/15 Headache, swelling L axilla, by 6/18 - chest pain, pressure. ED visit: testing revealed increased troponin and pos D Dimer. Cardiologist consulted, hospitalized on telemetry while waiting for transfer. Diagnosis myocarditis. Medicated with toradol, ativan initially with good response. Later dexamethasone for myocarditis and metoprolol for tachycardia. Hospitalized, still awaiting transfer at the time of this report.

Patient presented to the ED and was subsequently hospitalized for severe sepsis within 6 weeks of receiving COVID vaccination.

1 week and 2 days post vaccination I woke up with a tender reactive axillary lymph node in the left extremity. Around this same time erythema and a mild pruritus was noticed at vaccination site. Area was warm to the touch. No treatment was started.

After receipt of the vaccine, I developed a low grade fever the next day (1/7/21) that persisted throughout the day until it progressed into a fever of at least 101.3 F at night. It might have been higher, but that was the best reading I could get. It felt like the fever came on extremely fast bc all of a sudden I started shaking vigorously with rigors and chills. I couldn't get out of bed without experiencing the most uncomfortable chills I've ever experienced. I previously had Covid in early November, and this fever felt worse than what I experienced when I actually had Covid. Also, I experienced moderate to severe pain in my left arm on 1/7/21 at the injection site, which was far worse than any other muscle soreness I've experienced from any other vaccine I've received. The hour preceding the sudden fever attack, my left arm was feeling blazing hot, looked a little red, and swollen. I also experienced a strange allodynia type pain, whereby parts of my body hurt from simply touching them. Although I did not develop a significant rash, I experienced pruritus all over my body, predominantly affecting the areas around my ankles and wrists. I have a hx of multiple dermal filler injections in my lips. I don't think I had any problems with my lips after the injection. But other symptoms that I developed included a tickle in my throat and some shortness of air. On 1/8/21, I woke up drenched in sweat so I presumed that I broke my fever while sleeping. I have felt much better ever since. I'm a nurse practitioner student, and I had to miss a day of clinical on 1/8/21 bc of this reaction to the vaccine. I used ibuprofen the morning on 1/7/21 and Tylenol at night on 1/7/21 to bring down my fever

Supraclavicular Lymphadenopathy at the ipsilateral side of injection site. Slight L arm soreness, not severe. Denies fevers/Nausea/Vomiting

About 4 hours after dose, started to have a flat, non-itchy rash develop on chest and upper abdomen. Has slowly gone away since, but there is still some of it left. About 8 hours after dose, had severe chills, likely fever (did not measure), and lots of shivering. Skin felt very sensitive all over body. Arm was already sore at this point. Fatigue, drowsiness. Felt like a flu. The next day, large red splotch on left arm at injection site, with red line extending into the armpit area. Swollen lymph nodes in neck. Previous symptoms resolved, except for chest rash. Two days later, large red splotch on left arm at injection site is now very itchy and warm, firm, and slightly raised.

101C Fever (2-3 days), Severe Body aches (concentrated around lower spine; 5 days), Headache (6 days), Fatigue (3-4 days), trouble talking (hazy mental state; 5 days), Lymphadenopathy (Right-side neck; 15+ days), soreness (right arm; 15+ days)

24hrs after vaccination severe myalgia, chills, headache, nausea, diarrhea, swollen lymph nodes, loss of appetite, and fatigue continued into 02/02/2021

Member reports going home the night of the vaccine and having a fever of 103, with chills, and fatigue. The next day the individual noticed swelling in the face, hands were itchy and tingly, and also skin welts in the back and shoulder area. Member went to urgent care and was advised to buy Zyrtec which he stated helped. Member has since recovered and is doing fine.

Patient developed throat swelling, chest tightness, dizziness, and headache ~30 min after vaccine administration. Benadryl 50mg was given (11:00am) , throat swelling continued and Epi pen was administered 35 min afterwards (11:35am). Advil given at 11:50am. Vitals remained stable

Patient came back to the vaccine room on 15MAR21 to report swollen lymph nodes in his neck that started on 12MAR21 @ 2000.

Arm pain, swelling, chills, arm is hot near injection site Started Friday afternoon, worsened Saturday Improved Monday but swelling and pain increased Tuesday

PATIENT HAD A SHINGLE LIKE RASH ON THE LEFT SIDE OF HIS CHEST BY NIPPLE AND ARMPIT AREA. ON THE 20TH IT WAS JUST RED, BY MARCH 31ST THERE WERE RED BUMPS AND SCARRING. HE ALSO HAS 7 CIRCULAR SHAPED DARK RASH MARKS ON HIS BACK (THESE DEVELOPED MORE RECENTLY, EXACT DATE UKNOWN). PATIENT STATED ON MARCH 20TH THAT HE HAD NO PAIN, THE RASH WAS ITCHY AND SENSITIVE ONLY.

Swelling/knot at site of injection, mild itching. Appeared late in the day, nine days post-vaccination. No other symptoms currently.

9 days after receiving the vaccination the patient developed a rash on hands and feet. It has progressed to his arms, legs, chest, and stomach. The rash has welts and is itchy and even hurts. Patient is currently taking Benadryl and Zyrtec. He has not seen a doctor yet.

Swollen and tender lymph nodes under armpit of injected arm. Large red rash on arm where injection took place.

Systemic: Allergic: Anaphylaxis-Medium, Systemic: Confusion-Medium, Systemic: Dizziness / Lightheadness-Medium, Systemic: Fainting / Unresponsive-Medium, Systemic: Flushed / Sweating-Medium, Systemic: Hyperventilation-Medium, Systemic: Hypotension-Medium, Systemic: Shakiness-Medium, Systemic: Weakness-Medium, Additional Details: immediately after first dose pt head started to lower, eyes closed, slid down in chair. respiratory rate decreased for several seconds then panic breathing occured thereafter. pt was sweating profusely and skin was cold and clammy. could not verbally respond for 30-45 seconds. after a minute pt could talk and answer question. blood pressure was taken 3 different times 5 minutes apart 75/43, 87/46, 93/52. Pt was feeling fine a half hour later and was called 4 hours later to follow up.

The patient developed high fever to over 103F on the day of vaccine. 2 days later, he developed a red rash on the right side of his forehead, and in the next 4 days, swelling of right side of his face, right cheek, right temple, mandible, right ear, with difficulty of chewing, and some decrease in hearing in the right ear. The patient never had dermal fillers. I saw the patient today and put the patient on Prednisone and Keflex empirically, and referred him to dermatologist and plastic surgeon for 2nd opinion.

Anaphylaxis / anaphylactic shock, hot feeling in throat (a few minutes after receiving second dose), tightness in throat, difficulty breathing, hyperventilation, shallow breathing, wheezing

I woke up with pressure on my chest and pain on my left arm around the elbow. After a couple of minutes, I began to have a lot of cold sweat, and both the pressure in my chest and pain in my arm began to increase. Then I began feeling a tingling sensation on my neck/chin. After that, I felt lightheaded and decided to go to the hospital. At my arrival to the ER, I was given aspirin and heparin. I got a couple of EKGs and a chest X-Ray, as well as some blood work. I was then transferred to the medical center, where I had some more blood tests and EKGs done. I was also treated with Indocin, Lipitor and Aspirin. At around 9PM, I began feeling the pressure on my chest again, although with decreased intensity. I was given morphine and the pain went away. This event repeated at around 10AM next morning with the same outcome. After that I got an Echocardiogram, and began to be treated with Metoprolol. No other pain events happened for the rest of my stay at the hospital. On the next morning, April 26th, I was taken to an angiogram to rule out Coronary Dissection. After the test, I was discharged with a prescription for Metoprolol.

Redness/swelling of arm 24 hours after shot. Fatigue/tiredness next morning (12 hours after). Flu-like symptoms (nausea headache) and body aches next afternoon (24 hours after).

Swollen lymph node in the left neck area, above the clavicle bone. The doctor estimated it as a 2cm swollen area.

I woke up around 6am with a terrible headache, body aches and nausea. Around 3pm, I began experiencing a fever of 101.3°F and chills. The fever, chills, headache, and nausea have subsided, but body aches remain. I am also still experiencing what I believe to be swollen lymph nodes around my collar bone.

Side Effects: Headaches, Dizzness/ Syncope, Opposite arm pain, wrist pain, (R) shoulder blade pain and stiffness. Painful non healing rash on buttocks, Rash on (L) arm, large lump on (R) side lower back of head DR's Visit ER Visit

Hives Both Arm and Upper Body - Moderate Swelling Decreased pulse left hand. Moderate Swelling with Erythema - Sent To ER for Evaluation and Doppler to evaluate for Blood Clot

The patient had his 2nd Moderna vaccine on 4/21/21. He had headache and malaise for 2 days that resolved. On 4/24, he developed chest pain radiating to his jaw and left upper arm. He presented to the ED, he had an elevated troponin of 2.24 increased to 12.87. EKG showed ST elevation consistent with myocarditis. He was transferred to RRH and underwent cardiac cath on 4/26 which showed no CAD. He was not febrile. He was treated with metoprolol

Patient presented to ED via ambulance at 5:00am on 5/19/2021 after experiencing difficulty breathing and facial swelling about an hour prior. The patient has experienced significant allergic reaction in the past. On arrival of EMS the patient was noted to have difficulty breathing and angioedema of the lips. Patient received epinephrine 0.3mL IM and Benadryl 25 mg IV prior to arrival. On arrival to the ED the patient was noted to have no respiratory distress, signs of urticarial skin rash, vomiting, abdominal pain or diarrhea; no noted stridor or dysphonia; patient denied difficulty swallowing. ED notes state patient possibly ingested peanut-containing food prior to reaction onset, but this was not confirmed.

Vaccinated 5/20/21. Onset of chest pain 5/26/21. Admitted to hospital 5/28/21. Dx of myopericarditis. Treated with bedrest, analgesia, and telemetry monitoring to r/o ventricular arrhythmias. Patient was recovered 5/30/21 and discharged.

Palpitation; Heart was acting erratically; Numbness on the left side; Puffiness on the left side; This case was received via an unknown source (no reference has been entered for a health authority or license partner) on 04-Jun-2021 and was forwarded to Moderna on 04-Jun-2021. This spontaneous case was reported by a consumer and describes the occurrence of PALPITATIONS (Palpitation), HEART RATE ABNORMAL (Heart was acting erratically), HYPOAESTHESIA (Numbness on the left side) and SWELLING (Puffiness on the left side) in a 25-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 039B21A) for COVID-19 vaccination. No Medical History information was reported. On 01-May-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 29-May-2021 at 10:00 AM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 29-May-2021, the patient experienced PALPITATIONS (Palpitation) (seriousness criterion hospitalization), HEART RATE ABNORMAL (Heart was acting erratically) (seriousness criterion hospitalization), HYPOAESTHESIA (Numbness on the left side) (seriousness criterion hospitalization) and SWELLING (Puffiness on the left side) (seriousness criterion hospitalization). The patient was treated with LORATADINE, PSEUDOEPHEDRINE HYDROCHLORIDE (BENADRYL 24 D) at a dose of 1once a day; IBUPROFEN (ADVIL 12 HOUR) on 29-May-2021 at a dose of 1 UNK and PARACETAMOL (TYLENOL) from 29-May-2021 to 30-May-2021 at a dose of 1 UNK. At the time of the report, PALPITATIONS (Palpitation), HEART RATE ABNORMAL (Heart was acting erratically), HYPOAESTHESIA (Numbness on the left side) and SWELLING (Puffiness on the left side) had not resolved. No relevant concomitant medications were provided. The reporter was in contact with physician and also went to emergency room (ER) but they were not able to resolve the problem. The reporter confirmed that these side effects were still going on. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

Patient received second dose of Moderna COVID 19 vaccine on 6/4/21. During this same time, patient also had URI diagnosed as bronchitis at an urgent care and provided albuterol inhaler. Cough and URI symptoms subsided on approximately 6/12/21 but developed SOB, lightheadedness, and palpitations thereafter prompting presentation to ED on 6/15/21. Patient was started on digoxin, heparin, and furosemide by cardiology team. Work up in progress.

Mild Chest pain began to occur roughly a week after vaccination. Two weeks after vaccination it had processed to severe bouts of pain accompanied with dizziness and fatigue. After about a week of severe pain, the pain began to taper off and seemed to move from my chest more into my armpit and arm. A swollen and painful lymph node occurred in my left armpit roughly 2 weeks after severe pain had started. The lymph node is currently still swollen but it's getting mildly better. Chest pain is not entirely gone but it's also getting better slowly.

In addition to CDC expected symptoms (swelling of the face, tiredness, headache, muscle pain, chills) I experienced nausea, coughing, sore throat, vomiting or gaging after food or coffee.