Moderna

This is a 40 y.o. female who presents with abrupt onset of nausea vomiting, diarrhea, myalgias, headache about 2 hours after receiving her 1st Moderna COVID-19 vaccine at 1300 hrs.. She describes myalgias extending from the area of her left deltoid injection site over her shoulders and over her entire upper body. No neck or back pain. She describes diffuse throbbing headache with no positional component. She has had relentless nausea vomiting and retching. She has been up vomiting stomach contents to bile multiple times. She has had loose watery brown diarrhea multiple times. She describes diffuse abdominal crampy pain with increased tearing retching and vomiting. She denies any shortness of breath cough or wheezing. Voice is normal. No swallowing dysfunction or pain. No intraoral or facial swelling. She denies rash or pruritus. No arthralgias. Patient reports prior anaphylaxis with shortness of breath and tight airways, difficulty speaking and swallowing, and relationship to coconut ingestion few years prior. No other known food/nut reactions. Patient is a CNA for care at home. Last Covid test was 2 weeks ago which was negative. She reports she has been tested every 2 weeks routinely. Review of Systems Cardiovascular: Negative for chest pain and palpitations. Gastrointestinal: Positive for abdominal pain, diarrhea and nausea. Negative for vomiting. Musculoskeletal: Positive for myalgias. Negative for arthralgias, back pain and neck pain. Neurological: Positive for headaches. Negative for dizziness, weakness and numbness. Physical Exam BP 126/73 | Pulse 120 | Temp 37.1 °C (98.8 °F) | Resp 18 | Ht 1.575 m (5' 2") | Wt 68 kg (150 lb) | SpO2 100% | BMI 27.44 kg/m² ED Course as of Dec 30 2340 Wed Dec 30, 2020 2128 Reevaluation: Nausea improved. Abdominal cramping resolved. No further diarrhea or vomiting. Still complains of headache and muscle cramping through her upper shoulders and arm. Will remedicate with steroid and acetaminophen 2258 Reevaluation: Patient improved. Pain/myalgias improved. Headache now mild and dull. Continues with no further.nausea vomiting or diarrhea. She would like to try fluids at this time. Assuming toleration we will plan on discharge home. 2326 Reevaluation: Patient feels improved. Headache essentially gone. Taking p.o. fluids well. Discharge instructions discussed. She is very familiar with an EpiPen because of her daughter's prior use. Discharge instructions discussed. ASSESSMENT and PLAN This is a 40 y.o. female who presents with nausea vomiting diarrhea, myalgias, diffuse abdominal cramping, severe global headache, onset about 2 hours after first dose Moderna COVID-19 vaccine. Exam with intact mental status, neurologic system. Abdomen with some diffuse tenderness but no evidence of peritoneal sign. She had diffuse palpable soft tissue muscular type tenderness through her upper extremity shoulder and bilateral paraspinal back. She had no meningeal signs. She had no cardiorespiratory signs or symptoms. Her chest was clear. Voice normal. Swallowing normal. Oropharyngeal region normal. Initial ED ED management focused on rehydration, antiemetics and subsequent treatment for presumptive anaphylaxis with likely system involvement gastrointestinal and neurologic. She was treated with Solu-Medrol, famotidine and acetaminophen. She improved during ED course and did not require epinephrine. Symptoms at ED reevaluation/discharge were resolved. Clinical impression favors anaphylaxis over medication side effect given time course and abrupt onset of symptomatology and signs. She has a distant history of anaphylaxis to coconut-based product in her past. She has no history of ongoing allergic chronic history otherwise. Other organ systems appeared stable at onset and through ED course including cardiovascular and pulmonary. Plan is for discharge home with rest fluids. She will have a course of steroids/prednisone and famotidine. She was sent home with an EpiPen and understands use and precautions. Discussed ED "return immediately if" parameters with patient. Ongoing FOLLOW UP evaluation/care coordination via PCP recommended. Patient voices good understanding of current evaluation, follow-up & return recommendations and discharge instructions. Encounter Diagnosis Anaphylaxis due to vaccination, initial encounter Plan: -d/c home. No work next 2 days. Off work note provided -COVID-19 testing pending -rest with activity as tolerated -diet as tolerated & increased fluids as discussed -acetaminophen PRN -Prednisone 40 mg daily to finish 4 more days -Famotidine 40 mg daily to finish 4 more days -Zofran as needed (patient has at home) -Loratadine 10 mg OTC as needed -PCP f/u -ED return for interval worsening -instructions discussed & as documented

Headache, NauseaVomiting, Starting 1/4/21 evening, experienced HA, NV, and lymphadenopathy in left axilla through 1/6/21 Narrative: Took OTC tylenol for HA

PAIN, TENDERNESS AND SWELLING OF THE LYMPH NODE AT LEFT SIDE: ABOVE CLAVICLE BONE, LOWERSIDE OF LEFTSIDE NECK AREA.

Muscle knot at location of shot developed 24 hours after receiving vaccine. 48 hours after shot developed bruising. 96 hours after shot arm pit has become swollen and swore. 96 hours till current date/time of 6 days later swelling and soreness to arm pit progressively getting worse.

The shot was administered in my left arm. I experienced localized swelling and axillary lymph node tenderness immediately after injection under my left armpit. The right side of my face also became numb for about 5 minutes. The next morning the areas around my eyes were swollen and I had two styes in my right eye. I do not know if these were related. These symptoms lasted approximately 3 days. Some minimal swelling and tenderness seemed to remain, and approximately a week later I experienced a painful resurgence of the swelling at the injection site that was far larger, harder and more painful. I took Benadryl and Ibuprofen. These relieved the symptoms within 48 hours.

Onset at 14 hours - malaise, fever, arthralgias for 36 hours Onset at 36 hours - Facial burning, redness, swelling

Initially, no immediate problems other than slightly tender at injection site. Approximately 48 hours later (evening 01/14/2021) started to notice increased inflammation about the size of a "quarter" on left side of chin. I did have a pimple/ingrown hair at this site prior to the injection which was mostly healed but not entirely healed. The next morning, 01/15/2021, I experience mild facial numbness to the left side of my chin and mild facial paralysis resulting in an asymmetrical smile, and mild swelling to the left side of my face. Two day later (morning 01/17/2021) with my symptoms not worsening but showing only a little improvement, I went to my local urgent care for evaluation. Provider was not 100% sure of the diagnosis but felt this could be a case of shingles or folliculitis. I was treated with a 7 day course of acyclovir and a 10 day course of doxycycline hyclate. The numbness subsided 2-3 days after treatment began. The facial paralysis and swelling showed much improvement (90-95%) after completing the acyclovir on 01/24/2021; however, I feel there is still a little more improvement to go.

I received my Vaccine on 1/19/2021, on Friday 1/22/2021 my arm pit/Lymph node started to hurt. Then one week later on 1/26/2021 I started having vaccine shoulder itchiness I didn't think anything of it and then my arm swelled and got hot. The next day on 1/27/2021 it had a red area around it and was hot. I have never had a fever or anything else except minor pain the day after the vaccine. I continued ibuprofen and benadryl at night it took the itch away and was bearable. I want to know if I should get the second shot? I have it scheduled for 2-15-2021 @ 2:00 pm PST I also have pictures

01/30/2021 12:01 AM Headache, Body Ache and temperature 101 01/30/2021, Came to work, symptoms progressed and went home which included HA, body aches, pain at the injection site, chills, sweats, temp 103.9, started noticing, lymph nodes swollen slightly in left axilla where injection was placed 01/31/2021 decrease in body aches, temp 100, lymph nodes swollen in left axilla area 02/01/2021, lymph nodes almost back to normal, no other symptoms

On Day 5 after first shot I had extreme pain in injection site that was red swollen and hot. Also my left armpit was so swollen there was no longer a visible armpit. This has lasted for a few days now.

Facial swelling and pain along the entire left face, on the same side as the injection site. Severe temperature of 101 degrees with intense chills and body aches.

Elevated heart rate (130 at rest for 10+ hours, my normal is 70-80) Elevated blood pressure (150/89 at rest for 10 + hours, my normal is 110/70) Extreme headache, light sensitive Nausea Mild anaphylaxis itching/burning/tingling in lips, tongue and throat Feeling of intoxication, disoriented, slurred speech, dizziness Rash/redness that spread beyond injection site on to back of shoulder Agitation Itchiness Peeling of skin in mouth/cheeks Blisters on roof of mouth Chest tightness with normal breathing Jaw pain Treatment as listed below; continue with Benadryl every 6 hours and ibuprofen; return if symptoms continue or worsen

Diffuse allergic reaction with urticaria, mild difficulty breathing the next day, right upper arm swelling.

At 36 hours after injection, lymph node under right arm became swollen and tender. On day 3, the swelling is the size of a tennis ball and tender.

Uncontrollable shaking; rise in blood pressure; hives; (stomach, back, face, injection site) high heart rate; swelling in face and neck; shortness of breath.

2/7/2021 Sore muscles at injection site 2/7/2021 Enlarged lymph nodes in left armpit (same side as injection). 2/26/2021 Headache/Fever/Chills for less than 24 hours

All symptoms started 6 hours after second moderna vaccine - CC - Fatigue ++, swollen glands, body aches - back pain, fever. Fever for 5 days. Bad headache. + bleeding gums 3/4/21 with rash to hands, arms today.

Patient states that approximately 2-3 days post-injection he began to have swelling in throat, neck, jaw, and ear on the left side of body. He states that it was severe swelling and that he had difficulty swallowing. States that he took OTC antihistamine in large doses. Rates the severity of his condition on a scale as 10/10. Approximately three days post onset, he states his condition is now 6-7/10.

Patient received vaccine on 3/6/21 in the afternoon and his symptom started in the early morning of 3/7/21 continuing today with subjective fever, chills, facial pain, and mouth blisters. Has used APAP for fever control, last dosage yesterday night. Patient complains of difficulty eating due to lip swelling and blisters. On physical examination, patient is afebrile, has lip angioedema and multiple blisters on perioral region. Patient has difficulty opening his mouth due to lip swelling and pain. Patient was prescribed prednisone 40mg po qd for 5 days, acyclovir-hydrocortisone 5-1% topical, Lidocaine oral viscous solution for oral pain control as needed, OTC ibuprofen recommended as needed

Approximately 1 week later started to develop a rash on inner thighs. It continued to get worse over the next week, spreading over thighs, down legs and on arms. Very itchy, blotchy hive-like. Thighs developed swelling and bruising over the next week.

It was my second shot. It is two days later and the injection area now covered by a 2-3inch diameter red swollen rash. It looks like a red circular patch. Warm to the touch.

Extreme fatigue. Swollen lymph nodes in the arm pit of the arm receiving vaccine. Extremely swollen and painful.

PATIENT HAS NO MEDICAL PROBLEMS AND IS VERY ACTIVE , GOES TO THE GYM REGULARLY AND DEVELOPED NAUSEA AND EPIGASTRIC PAIN ON THE 3/17/21 , 3 DAYS AFTER RECEIVING MODERNA SHOT . HE SAID HIS PAIN HAD BEEN PROGRESSIVELY GETTING WORSE. HE SOUGHT CARE AT THE HOSPITAL ON 3/27/21 AND WAS DIAGNOSED WITH PANCREATITIS AND SENT HOME . RETURNED TODAY, 4/1/21 WITH SAME AND CONSTANT ABDOMINAL PAIN. LAB WORK AND EXAM SHOWED FINDINGS CONSISTENT ACUTE PANCREATITIS. PT DOES NOT DRINK OR USE DRUGS. ONLY SMOKES 3 CIGARETTES A DAY. I HAVE ADMITTED HIM TODAY AND WILL BE FOLLOWING HIM

On 4/8/21 awoke to intense pain in his left foot about 12 hours after receiving his 1st dose Moderna vaccine batch #038B21A. Over the next few days swelling and pain increased in the left foot moving around from the big toe, to ankle, to arch. His foot was swollen and extremely painful and he was not able to walk or put weight on the foot. On 4/18 he went to the clinic. The doctor took fluid from the big toe joint to test uric acid levels. Elevated levels of uric acid confirmed his condition to be Gout and Indomethacin was prescribed for pain and swelling. He has never had Gout or any kind of arthritis, joint pain or foot injury prior to the Moderna vaccine. As of 4/13/21 he is still unable to walk or sleep well due to pain and swelling in the foot. He is not able to work or resume normal daily activities.

PATIENT WITH FOLLICULITIS, CURRENTLY TAKING CIPROFLOXACIN 1 DAY IN EVALUATION AS PRESCRIBED BY HIS PCP. MILD LYMPHADENOPATHY,NO DISTRESS, NO URTICARIAL RASH, NO FACIAL OR ORAL MUCOSA SWELLING, NO DISTRESS, PT DISCHARGED HOME WITH FOLLOW UP WITH PCP

Visual defitict: floaters and blurry vision, headaches, swollen lymph nodes, involuntary tremors, numbness and tingling, progressively worse since his 2nd Moderna vaccine on March 29, 2021 Unable to see neurologist, earliest appointment 30 days out.

Left face swelling along jaw line, exacerbated by chewing, painful when eating, but otherwise just sore. No issues with breathing

Exactly 2 weeks from the date of the vaccine my Husband was diagnosed with a bad case of shingles. He has never had them before, since the vaccine he had swollen lymph nodes in the neck, under the chin, and head. His skin has felt itchy and burns a times. Three days ago his skin hurt to touch and last night on April 25 he started getting a rash under his arm. This morning it had spread across his back and chest. We went to the Doctor and he was diagnosed with shingles.

Entire left arm, all the way from shoulder to the fingers swelled up to 1.5 times the normal size. The left index figure and thumb started tingling and became numb. The pain is present in the front and back of the left shoulder as well. Saw a Dr and she told me to take 4 x 200mg Motrin every 6hrs for next 4-5 days. She also gave Tylenol 3. The pain was so acute that I asked my doctor to just chop off my arm. I couldn't sleep, I couldn't stand, sit or lay down. It hurt all the time. Lost all strength in the left hand and arm. Motrin and Tylenol didn't help with the pain. The swelling went down quite a bit in 3 days. Motrin caused a flare up of Crohn's. Saw another Dr 5 days later. She prescribed gebapentin, flexrel, norco, toradol, etc. It's now been almost 20 days since the injection. The pain has subsided but not completely gone. I am still unable to do much work and it hurts just to sit! I still have pain and still do not have my strength back. I am still unable to go back to work.

Swollen lymph node, rear left side of neck. Sore grape size raised lump on lymph node. Lasted 7 days before subsiding

101 fever, Headache, body aches - started 14 hours after shot, ended about 30 hours after. Sore left arm and swollen armpit lymph nodes - started 2 days after shot still subsiding 4 days later

Shoulder Injury Related to Vaccine Administration (SIRVA). The Nurse Practitioner administered the shot too high on my arm, up near the shoulder. As a result, the shot was injected in or near the bursa, causing extreme pain, limited range of motion, and potentially long term damage. I was diagnosed with Bursitis in the hospital two days later following a CT scan. It does not appear the standard "two finger width" approach was followed to ensure injection into the deltoid muscle. I am still in chronic pain. I've received tramadol, percocet, and a corticosteroid injection. I have a consultation with an orthopedic surgeon next week. My shoulder was fine prior to the administration of the second vaccine, which seems to be due to poor technique by the nurse practitioner who administered it.

Lower left ankle became hard & red with swelling in rear calf on 18th day after first dose. PCP suspected lymphatic bacterial infection & prescribed Keflex 500mg t.id. for 10 days. After 10 days condition had not changed. I experienced no pain throughout the entire event, only felt tightness in skin on calf from swelling. Bilateral ultrasound performed & results negative for DVT in both legs. Final Dx is Superficial Thrombophlebitis. Treatment plan is to elevate affected left leg & apply warm compress when possible & wear compression stockings when standing for extended periods.

Patient called in and reported he developed "swollen/flared up lymph nodes" 3 days after receiving the first dose of the Moderna COVID-19 vaccination. Patient received his vaccine at a local pharmacy. Patient stated he "has no medial history". Patient followed up with a doctor in the health system in. He stated that doctor prescribed him an antibiotic and ran some blood tests.

Patient received COVID-19 vaccine at 10:00am. Developed facial swelling (lips, eyes, face) 2-3 hrs later. Went to ER on 5/19/21 @ 06:00. Was given "2 shots" and observed x 3 hrs, then sent home with Benadryl.

Patient observed to become unresponsive and slumped over in chair during observation at appros 15 minutes. He remained unresponsive to verbal and physical stimuli for approx 5 minutes. Once responsive, he c/o pain all over, abdominal pain with curling up as if cramping. no muscle spasms observed. Skin with mild tenting. vitals monitored, NS IV given, ~150 cc given prior to transfer to EMS. Lorazepam 0.5mg IV given for muscle spasms. Diphenhydramine 25mg IV administered Labs drawn. Oxygen saturation 99% initially with NRB, changed to NC and remained >94% on 2 lpm. patient remained somnolent, not answering questions, though conscious.

pt says his left leg started swelling a couple of weeks after taking the vaccine. The swelling is mostly around the ankle and foot area. Pt states the swelling always stays the same and never goes down.

pt had redness in left eye. He had a small bump in his eyebrow and more redness around his nose. The redness was spreading on his face. On 6/1/21 he went to PCP. He was diagnosed with Herpes Zoster. He was prescribed Valtrex. He says the headaches are getting worse and has deep internal face pain so he called doctor and will have a FU phone appt on 6/2/21.

PT REPORTED LEFT ARM UNABLE TO MOVE PAST HIS ELBOW AND STRETCHED ABOVE HIS HEAD. HE DID NOT GO TO ER BUT RATHER TOOK TYLENOL AND USED ICE FOR SWELLING.

Presented to ER with fever, chills, cough, shortness of breath and diarrhea. Suddenly became hypotensive and diaphoretic in ER, which prompted hospital admission. Had 1/2 positive blood cultures during admission of coagulase negative staph, which was thought to be contaminant. Recieved 1 dose of IV vancomycin during stay. Required supplemental oxygen during admission and received 2 doses of dexamethasone while inpatient.

Blood clots (thrombus) found in my left thigh's vein, hence the swollen leg. I am not 100% sure if it's related to the vaccine though.

Left arm where got shot from moderns vaccine caused my left arm and armpit lymph node to swell to the size just smaller than a tennis ball.

After receiving the vaccine I came home from work and around 6:30 at night I started getting cold Chills then I would get hot. After tossing and turning all night with no sleep I got up at 5:45 a.m. I woke with a headache that lasted for about an hour and a 1/2 it went away then came back. Also when I was sleeping at night I noticed there was pain under my armpit. When I came home to take a shower I noticed my armpit was swollen In one spot. There is a little pain at the injection site but no swelling no redness.

Patient states received MODERNA vaccine 1/14/2021. 1/16/2021 developed severe muscle pain and fatigue starting in bilateral calves moving superiorly to the neck. Edema of BUE. Loss of strength in BUE. Pain in Bilateral groin. All progressively worsening . Sought medical evaluation on 1/19/2021. Labs drawn. Given NSAIDS and Cyclobenzaprine for muscle pain and tightness. Encouraged hydration. Revisit on 1/22/2021. Sx improvement, not resolutions. Muscle weakness present. Quick to fatigue, example writing name of form, extreme muscle fatigue and hand edema developed. Repeated labs.

Swollen lymph node in axilla and sore left arm. Started on 1/24. Took ibuprofen for symptoms. Has full ROM of shoulder. Symptoms persisting but improving. Pt to use ibuprofen and warm packs on site, will follow up with clinic if symptoms do not continue to improve.

swollen lymph node is axilla and sore arm. First noticed on 1/24. Have taken ibuprofen. Symptoms improving but still present. Will use warm packs and ibuprofen for symptom management.

Swollen lymph node in left neck on the same side as my Moderna COVID-19 Dose 1 vaccine (upper left arm)

Swelling in armpit lymphnode that started Sunday morning, 1/31 and continued to grow through Wednesday, 2/3. Started as lymph node about as big as a golf ball and continued to softball size. Swelling in clavicle lymph node that started Tuesday night, 2/2, and continued to grow through Wednesday 2/3. Swelling started about the size of a quarter, has grown to about a golf-ball

Cold sore inside part of lip, single angiodema type rash/hive on outside part of lip directly opposite cold sore, elevated resting heart rate at 95-105 (normal 71-80

pain on and around injection site. pain and discomfort with swelling in right arm pit. causes numbness if fingertips from time to time.

Had a very slight ache in back of neck about 30 min after shot. About 4-5 hours later my glands leading from the neck to my ears on both sides felt slightly swollen. It was not painful, but noticeable - sort of how you feel when you can tell a cold is coming on. My tongue also felt slightly swollen and a little bit of dry mouth. symptoms disappeared By the next day.

On Feb 14 developed Covid arm rash on left arm below site of injection. Rash spread over the course of 2 weeks and was red and hot to the touch. March 2nd left hand was achy and couldn?t open and close the left hand. March 4 rash spread to RIGHT upper forearm and is symmetrical with left arm. March 6 woke with swollen heel on right foot and painful and tender marking it difficult to walk.

Patient had first covid vaccine on 2/26/21. On 3/10 patient woke up with swollen nodules on his neck. Suspected lymph node swelling with hives noted.

It was the Moderna Vaccine. I had a prescheduled meeting to get some tests done on the Monday, following my vaccine (02/22/2021). The results of those labs showed a severe inflammatory response. My blood platelet levels were at 27, and my CRP was at 15. I started bruising easily, which I have never done before, and I had serious body aches and fatigue. I met with Dr. on Tuesday, March 16, 2021 to do some follow up tests. At this point, my platelet levels were up to 96, much improved, but still low. He said that it could very likely be connected to the vaccine. I had the first dose on January 23, 2021, and the second dose on February 20, 2021. I now have to get additional tests to see if these levels improve.

Soreness and swelling in injection arm - 1/2 hour after shot continuing to present 1:00pm 3/17 (26 hours after shot): unexpected low blood sugar readings throughout the afternoon 7:00pm 3/17 (32 hours after shot): slight fever (100.1), muscle soreness, body aches

After my first dose vaccine, I developed two large lymph nodes in the sub clavicular aspect of my clavicle, left side. I went to see my surgeon who palpated them and said that they would go down in one or two weeks. These lymph nodes are still present today and I am concerned because I do not know when they will go away.

Patient reported "hard lump in center of right armpit", feeling "hot and sweaty," and having "swollen, irritated, tight muscles in groin." Patient used OTC Ibuprofen for symptoms.

February 12 stareted developing a strong headache, numbness and tingling in arms and feet than it progressed to weakness on arms and legs in the next couple of days Got diagnosed with Guillain-Barre syndrome and was hospitalized form February 16 to February 23. Received 7 treatments of IVIG and am now recovering

41yo male with history of HLD, LBP, and tobacco use who presented to care initially at the with chest pain. He received the second dose of the Moderna vaccine on 18MAR21 at clinic and within 14 hours developed chills and myalgias. He denies any immediate onset of symptoms after receiving the vaccine. The following day he reports experiencing chest pain 24 hours after the vaccine was administered that progressively worsened over the subsequent 36 hours that finally prompted him to seek care. He describes the pain as a central non-radiating squeezing pain that worsened with movement and breathing. He waited to seek care because he reports several of the soldiers in his unit have experienced similar chest pain that eventually resolved. He reports being at his baseline health prior to receiving the vaccine and denies any fever, cough, rhinorrhea, congestion, malaise, vomiting, diarrhea, or rash. Upon initial presentation to care at clinic he was noted to have a Tropnon I of 0.9, WBC of 14, elevated CRP (7.3), and temp to 101.4. Patient was given ASA, Plavix, Lovenox, Tylenol, and Ceftriaxone. Since arriving to clinic and EKG was obtained showing ST elevation in lead 1 and avF concerning for ischemia and underwent a left heart catheterization which was clear of obstruction. Serial high sensitivity Tropnonin levels have been trended to peak of 465. Respiratory viral panel to include SARS COV-2 was negative. Cardiac MRI was consistent with myopericarditis, and show mildly reduced EF for 46%. Blood cultures have not grown any organism. His chest pain has resolved since starting Aspirin and Colchicine.

swollen lymph node in left underarm approximately size of tennis ball. pain in left underarm lymph node like muscle tear

Seringue broke while being administered the second Maderna Covid Vaccine, so I was given a second dose in order to receive full dose. Following day I had 102.8 fever and swollen lymph node under armpit. Fever broke but armpit is still swollen two days after receiving the second dose of the vaccine

Patient experienced a non-itching, non-blanching petechial rash across bilateral arms, trunk, and back beginning 5 days after vaccination. Biopsy revealed underlying vasculitis with eosinophils. The rash clears up with use of oral prednisone. Patient has also experienced edema and ulcers of the lower extremities believed to be caused by microeboli associated with vasculitis.

Approximately 54 hours after receiving shot I noticed a couple hives on the lower portion of my body. I didn't think much of it and went to bed around 10pm. I woke up around 1am on 3/20 and noticed that my lips were very swollen and I had several hives on the lower half of my body. Additionally my scrotum was enlarged. Other than the physical symptoms I felt fine - no fever, body aches, pain, or respiratory issues. I decided to go back to bed after taking 2 Advil. I woke up at 7am and was still having a reaction so I decided to go to the ER. While at the ER the gave me steroid and Benadryl which immediately started working to reduce the reaction. They took blood work which came back "essentially perfect" according to the Dr. I was discharged and prescribed an epipen, and a steroid which i took for two days. I was instructed to follow up with my primary care physician which I did on 3/26. The ER Dr believed that my reaction was caused by something that i had ate; however, to the best of my knowledge, I am NOT allergic to any foods. Shortly before the reaction I had eaten a can of ravioli and some bread. The can from a 12 pack that we bought at the grocery store approximately 6 months ago. It as the last can in the pack and I did not have a reaction to any of the previous cans. I met with my family Dr's PA the following week and she indicated that while there is no way to know with 100% confidence that the reaction was from the shot, she noted that it was highly unlikely that my reaction was from the ravioli can. The PA informed me that I needed to use extra caution should I decide to get the second shot. I am scheduled to receive the second shot on 4/14.

~12-18 hours after injection pt began to feel itchy with steadily worsened over the next ~36 hours. At that point he began to have angioedema and bilateral hand swelling and large generalized wheals. He never had difficulty breathing or swallowing. He was seen by another provider and given a solu-medrol injection followed by high, tapered dose of prednisone. 3 days after treatment pt returned to clinic and was seen by me. Swelling has resolved though he continues to have generalized urticaria. He is taking his prescription as instructed. No difficulty breathing or swallowing. Pt instructed to keep cool, continue his medication, and to f/u immediately for any worsening symptoms or concerns.

pain in arm since shot slowly went away the 7 days after my arm swelled and is very tender and painfull swelled entire muscle shot was given warm to touch pain to touch

Reporting per Moderna COVID-19 requirements n/v/d abdominal pain, elevated white count: appendicitis

Had a slight fever that developed overnight, aches at lymph nodes and fatigue. Felt normal but tired at about 11am. Also the expected arm soreness at the injection site. I had the same symptoms with the first shot but more intense and lasting all the next day. For the first shot I had just gotten over a cold earlier that week. Also on the second shot I made a point of drinking a lot of Gatorade the night of the injection and another the morning after. Otherwise I did things about the same for both.

The 21st, I only felt some fatigue and tiredness as well as the injection site was tender. The following morning, however, was very unpleasing!!! My entire left arm was swollen TWICE its normal size. The injection site was extremely tender to the touch. I could barely use my arm. I had to assist that arm with my other arm. I was extremely lethargic/tired/fatigued. So much that I was in bed 95% of that 24-36 hour time frame; unconscious!!! I was having sporadic "head changes" all day. I was very scared and worried!!! I was unable to perform task at home as well as was unable to work!!!

Noticed swollen lymph nodes in armpit 3 days after the 1st Moderna shot. Went for a run to get the body moving and try and hopefully reduce the swelling. However, this instead resulted in an inflammatory reaction in the toe joints of the left foot (and to a lesser degree in the right foot) that has persisted to the present day of May 16th - almost 2 months. The inflammation may be slowly receding, but exercise rapidly brings it back.

One week after the vaccine, 01/22/2021, very large inflamed lymph nodes. Under the arm, left breast tissue and left clavicle. The issue he went to the doctor, sore arm and fatigue. I saw the doctor, 01/25/2021. Determined an immune response to the vaccine. The inflammation was benign, the lymph nodes seem to be healthy during ultrasound exam. The patient has not recovered from the adverse event, I still have inflamed lymph nodes

had another heart attack¨; ¨Had 2 heart attacks¨; ¨Swollen feet¨; ¨Was very fatigued with little walking¨; ¨A lot of pain in the arm of the injection ¨( left arm); This spontaneous case was reported by a consumer and describes the occurrence of MYOCARDIAL INFARCTION (¨Had 2 heart attacks¨) and MYOCARDIAL INFARCTION (had another heart attack¨) in a 41-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 014C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. The patient's past medical history included Automated external defibrillator user (HOSPITALISED (07-MAY-2021 - 13-MAY-2021)), Coronary artery bypass graft (HOSPITALISED (07-MAY-2021 - 13-MAY-2021)) and Catheterization cardiac (HOSPITALISED (07-MAY-2021 - 13-MAY-2021)). Concurrent medical conditions included Diabetes, Blood pressure high and Hypertension (not adequately controlled "has high blood pressure levels but it is not constant so he doesn´t take medication for that".). Concomitant products included METFORMIN for an unknown indication. On 28-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 28-Apr-2021, the patient experienced VACCINATION SITE PAIN (¨A lot of pain in the arm of the injection ¨( left arm)). On 07-May-2021, the patient experienced MYOCARDIAL INFARCTION (¨Had 2 heart attacks¨) (seriousness criteria hospitalization and medically significant). On 13-May-2021, the patient experienced PERIPHERAL SWELLING (¨Swollen feet¨) and FATIGUE (¨Was very fatigued with little walking¨). On 20-May-2021, the patient experienced MYOCARDIAL INFARCTION (had another heart attack¨) (seriousness criteria hospitalization and medically significant). The patient was hospitalized from 07-May-2021 to 13-May-2021 due to MYOCARDIAL INFARCTIONThe patient was hospitalized from 07-May-2021 to 13-May-2021 due to MYOCARDIAL INFARCTION The patient was treated with TICAGRELOR (BRILINTA) from 07-May-2021 to 13-May-2021 at an unspecified dose and frequency; ATORVASTATIN CALCIUM (LIPITOL) from 07-May-2021 to 13-May-2021 at an unspecified dose and frequency; BROMAZEPAM (LAXYL [BROMAZEPAM]) from 13-May-2021 to 20-May-2021 at an unspecified dose and frequency; CARVEDILOL from 13-May-2021 to 20-May-2021 at an unspecified dose and frequency; CLOPIDOGREL from 13-May-2021 to 20-May-2021 at an unspecified dose and frequency; ACETYLSALICYLIC ACID (ASPRIN) from 13-May-2021 to 20-May-2021 at an unspecified dose and frequency; VALSARTAN from 13-May-2021 to 20-May-2021 at an unspecified dose and frequency and SPIRONOLACTONE from 13-May-2021 to 20-May-2021 at an unspecified dose and frequency. On 07-May-2021, VACCINATION SITE PAIN (¨A lot of pain in the arm of the injection ¨( left arm)) had resolved. On 20-May-2021, FATIGUE (¨Was very fatigued with little walking¨) had resolved. At the time of the report, MYOCARDIAL INFARCTION (¨Had 2 heart attacks¨) and MYOCARDIAL INFARCTION (had another heart attack¨) had resolved and PERIPHERAL SWELLING (¨Swollen feet¨) had not resolved. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown. Patient took the 1st dose of the vaccine on 28apr2021 and referred a lot of pain in the arm of the injection. On 07may2021 he was diagnosed with myocardial infarction and was hospitalized. On 13may2021 the patient got discharged to home with oral medication and an external defibrillator. During this period he had swollen feet and extreme fatigue. On 20may2021 the patient had another myocardial infarction, is currently hospitalized receiving Tridil as treatment and is requires a heart transplant. Company Comment: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. However the patient's comorbidities (diabetes and hypertension) are risk factors for myocardial infarction and pose as confounders of this event. Since the most recent event of myocardial infarction is life-threatening further information was requested regarding the event outcome.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. However the patient's comorbidities (diabetes and hypertension) are risk factors for myocardial infarction and pose as confounders of this event. Since the most recent event of myocardial infarction is life-threatening further information was requested regarding the event outcome.

Starting about 2-3 weeks after my 2nd dose of the Moderna COVID19 vaccine, I started experiencing daily joint/nerve pain and swelling. It affects different parts of my body each day, but the usual targets are my fingers, wrists, knees, and ankles. Sometimes, it is a pure nerve pain. Other times, it is paired with swelling, especially in the knees and fingers. I've experienced pain like this in the past, but very infrequently (once every few months at the most). But the pain has been on a daily basis ever since late-March/early-April and still persists today.

Swollen lymph node in collar bone started 4 to 5 days after first injection. Seemed to partially resolve after a week, but after second shot was swollen again. Still remains palpable 6.5 weeks after second shot.

Paralyzed completely. Sent to ER. Transferred to another ER and completed spinal tap, MRI, blood work. Outcome: guillain barre syndrome

1/13/21: enlarged left supraclavicular lymph node 1/14/21: CT chest showed enlarged left supraclavicular lymph node with fat stranding 1/18/21: bloodwork done, unremarkable swollen lymph nose, left neck and shoulder pain continued 2/18/21: Excisional Biopsy of enlarged left supraclavicular lymph node, results were inflammatory/benign continued left neck pain and swelling 4/26/21: MRI neck soft tissue performed, results unremarkable May 2021: mid-may drenching night sweats started occuring with paraesthesias in left upper extremity 6/2/21: Orthopedic consult-normal exam, EMG LUE ordered 6/3/21: bloodwork done, unremarkable 6/4/21: CT chest, abdomen, pelvis performed with unremarkable results 6/9/21: EMG performed and showed mild carpal and cubital tunnel syndrome around 6/12/21 muscle fasciculations in both legs started to occur 6/18/21: MRI Brain, unremarkable 6/18/21: Neurology Consult at Clinic-normal neurologic exam 6/22/21: Primary Care doctor started me on buspirone for anxiety related to neurologic symptoms diarrhea and weight loss since first moderna vaccine 6/23/21: GI consult performed 6/23/21: Labs and stool studies performed that showed low b12, stool qualitative fat split, stool with enteropathogenic e coli, stool with norovirus 6/25/21: B12 injections started weekly 6/28/21: EGD performed 6/28/21: Azithromycin 500mg x 3 days to treat e coli 7/2/21: ER visit for worsening fasciculations, unremarkable work-up 7/12/21: More labs from GI ordered, unremarkable 7/14/21: Consult for counseling due to anxiety related to neurologic symptoms 7/19/21: PCP follow-up 7/23/21: Neurology follow-up 7/27/21: GI follow-up

Patient had the normal flu-like symptoms for 2 days which included vomiting. He started to develop swollen lymph nodes in his armpit, but the it opened like a blister. Then, he had to be placed on antibiotics for the open wound.

Patient contacted the clinic on 6/21/21 with symptoms of an upper respiratory infection. Patient tested negative several times for COVID-19. He was treated with multiple courses of antibiotics with no improvement. Patient went in to the ER for shortness of breath and was diagnosed with Guillain-Barre Syndrome.

Guillain-Barré syndrome; orthostatic light headedness; Difficulty in walking; didnot feel great; Itching; short term memory; chest tightness; Brain fog; Numbness; Tingling; Pain; swelling of hands; joint pain; fatigue; swelling at injection site; Injection site pain; headache; Nausea; rash; Chills; This spontaneous case was reported by a consumer and describes the occurrence of GUILLAIN-BARRE SYNDROME (Guillain-Barré syndrome) in a 41-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 030L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. No medical history information was provided by the reporter. Concurrent medical conditions included Fruit allergy (Strawberries :Anaphylaxis + Angioedema), Seafood allergy (Shrimp) since 2012, Allergy to nuts (Walnuts[unsure]:Oral itching and jaw tightening.), Food allergy (Mushrooms[ nausea and vomiting]) since 1995, Anaphylaxis since 2012, Hay fever, Urticaria, Migraine, Diverticulosis since 2017, Connective tissue disorder NOS (Suspected), Eczema and Allergic rhinitis. Concomitant products included PLANTAGO OVATA (METAMUCIL [PLANTAGO OVATA]) for Diverticulosis, SUMATRIPTAN for Migraine, TRAMADOL for Pain, CETIRIZINE HYDROCHLORIDE (CETRIZINE) for an unknown indication. On 28-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, the patient experienced DIZZINESS POSTURAL (orthostatic light headedness), GAIT DISTURBANCE (Difficulty in walking), GUILLAIN-BARRE SYNDROME (Guillain-Barré syndrome) (seriousness criterion medically significant), FEELING ABNORMAL (didnot feel great), PRURITUS (Itching), AMNESIA (short term memory), CHEST DISCOMFORT (chest tightness), FEELING ABNORMAL (Brain fog), HYPOAESTHESIA (Numbness), PARAESTHESIA (Tingling), ARTHRALGIA (joint pain), FATIGUE (fatigue), VACCINATION SITE SWELLING (swelling at injection site), VACCINATION SITE PAIN (Injection site pain), HEADACHE (headache), NAUSEA (Nausea) and RASH (rash). At the time of the report, DIZZINESS POSTURAL (orthostatic light headedness), GAIT DISTURBANCE (Difficulty in walking), GUILLAIN-BARRE SYNDROME (Guillain-Barré syndrome), FEELING ABNORMAL (didnot feel great), PRURITUS (Itching), AMNESIA (short term memory), CHEST DISCOMFORT (chest tightness), FEELING ABNORMAL (Brain fog), PARAESTHESIA (Tingling), ARTHRALGIA (joint pain), FATIGUE (fatigue), VACCINATION SITE SWELLING (swelling at injection site), VACCINATION SITE PAIN (Injection site pain), HEADACHE (headache), NAUSEA (Nausea) and RASH (rash) outcome was unknown and HYPOAESTHESIA (Numbness) had not resolved. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. Lab test include: Cardiovascular evaluation include tilt table test, Rheum workup, Ultrasound were known to cause Rheum. No treatment information was provided. This case was linked to MOD-2021-058060 (Patient Link). Most recent FOLLOW-UP information incorporated above includes: On 11-May-2021: Follow-up Information received contains No New Information. On 14-Jul-2021: Updated Reporter address. Updated Patient demographics[Height, Weight, Race, Ethinicity ] .Added medical history include Allergies, current medical conditions. Added concomitant medications. Added Vaccine facility information. Added new Events.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

This morning I noticed 2 swollen lymph nodes at the base of my neck on the same side as the injection. They do not hurt, aren?t painful or red.

This morning I woke up and have 2 swollen lymph nodes at the base of my neck on the same side as the vaccine was given. They do not hurt, aren't red or tender, just swollen.

Two hours after vaccine, I had pain in the neck at my thyroid gland and what seems to be the lymph glands behind it on the right hand side. It was tender. I took tylenol to deal with it. That pain persisted all the next day on Friday and again took tylenol and ibuprofen to deal with it. Then Saturday AM I was awaked early with severe throbbing pain in same thyroid/lymph area, it hurt to swallow, turn my head, and the pain was radiating up to my right ear. I was also having cold sweats. I managed to get the pain down again with tylenol and ibuprofen. On Sunday I spiked a temp of 100.8 and was having flu like symptoms, like body aches and more chills. I got the temp down but my heart rate remained elevated and I found it difficult to catch my breath. This went on for hours. I eventually had to go to the ER, where my pulse eventually came down. Nothing like this has ever happened before. The ER staff could not explain what had happened to me. At the time of writing this on Tuesday, 5 days after vaccine, I again had a lot of cold sweats this morning and there is still some tenderness in the lymph gland area near above the right side of my thyroid gland, but I am feeling better overall.

Woke up at 2 am the morning after the injection with my arm extremely sore, swollen, red, and feverish to the touch that has continued for 4 days now. I also experienced a fever for 2 days after the injection along with dizziness, weakness, fatigue, headache, body aches, vision changes, and ringing in both ears. As of today 1/12/21 I am still experiencing symptoms even while using Benadryl allergy tablets by mouth and anti-itch cream applied to the injection site.

7 Days after 1st shot - I woke up at 0600HR with slight swelling at injection site on right arm. By 1800HR size of swelling had increased to cover all of upper arm, from elbow to shoulder. Extreme heat and pain followed. Use of Arm limit. Fever increased to 100°; Nausea; Fatigue.

Symptoms after 1st shot 12/23/2020- Severe chills, severe fatigue, headache - resolved after 24 hours. Symptoms after 2nd shot01/19/2021 - slight fatigue recovered after 24 hours. 4 days after 2nd shot - Developed cold sore on lower lip area. To my recollection, I have never had a cold sore before which is a bit concerning. I understand that I may contracted HSV-1 and not have know it as child. I am curious if somehow the COVID vaccine somehow compromised immune system to a degree that the HSV-1 is now active? May very well not classify as an "adverse event," but since I haven't heard of any such issues I thought I should report.

About 1:15 pm (an hour after shot), I was driving and noticed my face on both sides of my temples started to swell. I removed my sunglasses and noticed the swelling for about 20 minutes then it subsided.

Vaccine was injected into subacromial space instead of deltoid. Severe subacromial bursitis symptoms developed rapidly.

I had swelling and redness that kept getting bigger. The injection site was hot like it was almost infected. I had it checked out at the walk in clinic and they said it was an allergic reaction and to take Benadryl along with icing the arm. I was not the best at following this but once I started doing this is started to get better and was cleared up within a week.

I received my first dose of the COVID vaccine on January 12, 2021. I had a headache on the night of Jan 15 so took two Tylenol pills. I woke up with a worse headache so took two Excedrin Migraine pills in the morning. At about 10 am I started a 10 mile run, which is not unusually long for me. I finished before noon and when I urinated , it was almost all blood, which has never happened to me before. I went to the emergency room. They gave me IV fluids and took some blood tests. My creatinine levels were abnormally high but the doctor felt I overexerted myself and was too dehydrated even though the workout was not unusually for me. On January 18th, I developed a quite painful lump in my left armpit, that lasted about a week. I saw my primary care physician on Jan 23rd for a follow up. He thought the lump was a swollen lymph node from the vaccine and was not concerned. He scheduled blood tests and an ultrasound of my kidneys, all of which came back normal. I received my second vaccine shot on Feb 9th. I developed a headache that night and have had a headache most of the time since. I have taken several pills of Excedrin Migraine over these few days. I also traveled to San Diego on the 10th and did a fairly long and arduous hike up a mountain on the 11th. Although it was intense, it?s the type of hike I do several times a year and not completely out of the ordinary. I was also a bit dehydrated again. I woke early morning on the 12th with another headache so I took two more Excedrin MIgraines and went back to bed. When I awoke about 6am, I urinated blood again. I urinated blood for several hours and have finally drank enough water to end the blood urination. I normally work out intensely several times a week and do have bouts of dehydration. But I have never urinated blood before. I can?t help but believe it?s no coincidence that the two times in my life I?ve urinated blood have coincided with COVID vaccine shots. Not sure how my exercises, dehydration, and use of NSAIDs have contributed but something is going on and it needs to be investigated.

Moderna COVID-19 Vaccine Left arm swelled to double normal volume as compared to right arm - swelling went away after a week Imtermitant radiating pain on left side of body from arm to lower leg - stopped after 24 hours

Chills, headache and achy body follow day of second shot. Discovered marble/golfball size lump in left armpit work days after second shot . Slight discomfort. Lasted approximately 3 days . Small lump still present . Seen primary physician at peak of lump follow up scheduled .

On the first day I had a huge lump underneath my armpit I did not become too concerned with that I read it was something that could happen regarding the lymph node. 10 days later I woke up at 3:30 in the morning and had to dial 911 my throat felt like it was closing and my lips were both swollen. I went in the ambulance they brought me to the emergency room where they gave me Benadryl a steroid and some IV fluids. as soon as I receive the Benadryl my throat started to open up and my lips both started to go down . My lip continue to swell for the next three days on and off often on. Every time it swelled up I took Benadryl and every time sure enough it went away . The day I came home from the hospital I thought I was doing much better until that following night I became severely nauseous. I don?t know if it was something that they had given me in the hospital or still a reaction that was going on in my body, but I had some sort of stomach bug I threw up that whole day, had chills sweats and a pounding headache that would not go away for over 48 hours .I was unable to eat or drink for 24 hours and had to go to an urgent care where they provided me with some medication for nausea. My concern right now is I am hearing that the second shot hits a lot harder than the first one and if this was a reaction to the shot I am very afraid of what will go on if I get the second one. I cannot take a chance with my life. I really want to shot I work in an environment where I am working with the department which is why I was able to get the vaccine so early I feel safe being vaccinated I am very disappointed that this happened I just cannot take a chance having a family etc. Also I have very bad medical in Sherance so I am dealing with all of the bills from this hospital stay I have a deductible which I can?t afford and then only 50% is covered afterwards. That is the reason I do not go to the hospital under no circumstance unless I am dying which that night I was that scared I felt the need I had to go.

Appendectomy / Appendicitis on 3/29 3/18 that night stomach irritation developed. 3/19 stomach irritation continued and difficultly sleeping due to irritation, pain continued. 3/28 Pain became severe and couldn't sleep. 3/29 Went to urgent care, transferred to ER. ER did a CT scan and determined appendicitis. Emergency appendectomy performed.

Swelling of the under arm midaxillary location (arm pit) of the left arm. Pain with the swelling. High fever and body chills for less than 12 hours. Swelling and discomfort at the midaxillary point is still on-going over 24 hours.

Swollen, hot rash at the site of the injection a week later. There is also pain and swelling under the arm in an area that might be near a lymph node. I am not a doctor, however.

The patient's right hand swelled up, including pain. This is on the opposite side of the injection site.

patient stated red, itchy arm with swelling and no fever that started a few days after vaccine and lasted almost a week

Fever 101, joint pain, pain in the left arm and what caught my attention is a ball between the chest and the left armpit of half an inch in diameter when I touch it I hurt a little

Patient complained of swelling in his neck. Patient stated that this happens when he takes the flu shot also. Problem: swelling. A 24 /o patient complained of swelling around the neck. Nurse observed patients neck. no redness noted. patient had no distressed. Patient stated that he has swelling in his neck when he takes the flu shot. 1020 am vitals was taken BP 146/102, HR 85, RR 16 Temp - 97.2 02 Sat 98%, no sign of distress. Nurse observed patient for 30 mins. 1040 am vitals sign BP 147/95, HR 80, RR 16, 02 Sat 98% Patient stated that he felt better 1055 am patient was discharged with family. 03/17/21

Hives, blisters, swelling, and itching, pain covering both feet, legs The problem is ongoing and has not resolved itself

Swelling about 3" in diameter at point of injection. Swelling is firm, slightly painful to touch, and has been present for more than 48 hours. Overall body is itchy.

First several days I had mild aches and pains and lethargy. Around the seventh day I had chills and night sweats, and severe aches and pains and lethargy. Around this time I started to notice swollen lymph nodes throughout my body ? five around my head and ears and three in the groin area. I also found lumps in my neck and rib cage, though I?m not sure if these are lymph nodes. Three weeks later the lymph node swelling has diminished, but they haven?t disappeared entirely.

Site: Itching at Injection Site-Mild, Site: Redness at Injection Site-Mild, Systemic: Allergic: Itch (specify: facial area, extremeties)-Mild, Systemic: Allergic: Itch Generalized-Mild, Systemic: Allergic: Rash Generalized-Mild, Additional Details: Patient had itchiness at the injection site within 5 min of administration. Patient had redness and slight swelling. He was given 25mg of benadryl and checked up on 15 min after. Patient said the itching went down and the redness decreased. He went home with his partner and confirmed no further issues.

Shortly after the 2nd shot, at the 24hr mark, I felt the normal vaccine symptoms: swelling, joint aches, headache. I got over that in a week. Simultaneously, I had an acute flareup of my gout. I thought it was just joint pain, but when the normal symptoms went away, I realized the joint pain in my legs was still present. I haven't had a gout flare up in 2 years. The pain was the worse I have ever experienced. Within 5 days, I contacted a doctor. I was given a colchicine prescription. A week later, the gout cleared up. The weird thing is I feel like it is coming and going. It is unusual because when I have a gout attack, it is something that comes and leaves for about a year. Now, the gout is coming and going which is concerning to me because I have been taking care of it and it has been under control for some time now.

Patient developed lump at injection several hours after receiving vaccine. The next day, patient started to develop swelling in the left armpit/lymph node. The swelling continued to get worse and become painful. After the patient showed me the swelling, I suggested that they be evaluated at clinic care or the ER if unable to contact their PCP. In the meantime, I recommended that he take Benadryl and ice the affected area.

member was vaccinated on 12/29 - 1-2 hours later developed injection site soreness/swelling/chills/fatigue/intermittent headaches/"head cold like symptoms" - yesterday evening developed R facial swelling including to upper lip and numbness in face - is able to smile and use muscles normally no facial dropping but face is still puffy today after 50 mg Benadryl. Member has R inner ear itching but denies throat tightness/difficulty breathing

Soreness of deltoid resolved 2 days after vaccine. Normal shoulder for 7 days. Day 8 post vaccination onset of itching, swelling and redness of left should, continuing now x2 days. No other systemic symptoms. No pain.

Sweats, body aches, headache on the day of vaccination. Next day the patient experienced regional lymphadenopathy and arm weakness.

Initial shot did not even feel it. then a coldness in my shoulder. down my arm to wrist and up to my cheek behind my left eye, then over my sinus cavity to the right side behind my eye and to my ear. Got home from work and noticed my left side was kind of swollen. chest and back. It felt a bit like a bee sting. I slept on my left side. Woke up with numbness on my whole left side. face was numb. My wife said it was kind of like bells palsy. Face kind of twitched a bit. Hip was numb walking was slow and I was careful as I went to the grocery store . It kind of leveled out but stayed numb all of work. I was still swollen after work. Woke up on Sunday and my arm was hurting bad. numbness had dissipated. ate then suddenly felt flush and hot. fetal position on the bed for a half hour then I had to drag myself to work. felt bad the first few hours but as the night went on I felt better. I could always feel it behind my eyes. early on it felt like I was discharging a bunch of stuff from them. My body was literally numb on the left half. I could feel the middle of myself from my scalp to my toes.

I received my second dose of the Moderna vaccine at approximately 11:00am. At approximately 7:00pm, I began experiencing flu-like symptoms including fever, weakness, fatigue, severe body aches, a swollen axillary lymph node (on the side of the injection). 48 hours after receiving the shot, I still maintain a fever of greater than 100 and body aches.

Bilateral hands swelled up, increase in body temp. Patient took Claritin D at 1600 and symptoms subsided.

Patient called pharmacy around 9:15 am complaining about side effect after receiving Moderna Covid 19 vaccine 2nd dose. Patient was advised to see doctor immediately. Patient stated that he didn't had any reaction after getting first dose of Moderna Covid 19 Vaccine (Lot - 027L20A - Site : LD - IM) on 01/05/2021. As per patient, on Wednesday 02/03/2021 around 3 am woke up with high fever( 102.7), chills, body sore, joint muscle pain and feeling tired. On Thursday 02/04/2021 around 2 am had fever (99.7), leg pain, low back pain and swelling in left armpit. Has appointment with physician at 10:45am.

tennis ball sized swollen area on left side of the chest very close to the arm pit. There is a general constant pain which increases with movement and/or palpation. Tylenol PRN has reduced the pain but temporarily and not significantly.

Patient received his first Moderna (COVID) vaccination on 2/9 then started to develop generalized hives along with localized angioedema (occiput) several hours post vaccination

A few days after COVID19 vaccine administration on the patient's L arm he developed a L eye stye and a new L upper lip herpes labias outbreak, patient has a history of cold sores in the past. Patient applied topical abreva to the cold sore which he has used in the past resulting in upper lip swelling. Unclear if the upper lip swelling is a result of the abreava or delayed from the vaccine.

Tingling and swelling to lips with progressive tingling and swelling to chin area and neck about 5-10 mins post injection. Given Benadryl 50mg PO and Epinepherine 0.3mg/0.3mL. EMS called. Pt declined transport to hopital, opted to have wife drive him.

I HAD MY YEARLY PHYSICAL ON NOVEMBER 20, MY PSA WAS 0.84. NO ISSUES WITH MY PROSTATE, OR NEVER HAD ANY ISSUES. ON 2/3/2021, i DEVELOPED A SEVERE PROSTATE INFECTION WAS TAKEN TO THE EMERGENCY ROOM. MY PSA WENT UP TO 39 AND MY WBC WAS 23,000. IT NOW AT 14, BUT STILL GIVING ME ISSUES. THE ONLY THING THAT CHANGED IN MY LIFE WAS I GOT THE COVID VACCINE FROM MODERNA.

"43M yo started with symptoms of for __3 _days. Pt states has very swollen left leg , and red. with mild pain in the groin area to the left testicle.. Leg pain is Very bad Symptoms started after biking pt denies injury. Pain in located in the left leg Pt describes pain as severe and is associated with groin pain to left testicle"

Fever, very sleepy, a lump or cyst in the same place as the vaccine that disappeared and then appeared on my neck and I still have it.

Arm soreness and fever for lasting at least 12 hours on the day 1 following vaccine. On Day 2 following the vaccine, in addition to soreness at injection site, swollen lymph node and tenderness in underarm of left arm where vaccine was administered. On Day 3 following the vaccine, lymph node still swollen with tenderness with additional tenderness in bicep and forearm. Today is Day 4 after vaccine and lymph node is still swollen and tender, along with tenderness in bicep and forearm. The swelling and tenderness seem to be improving slowly.

Mild fever, body aches, arm swelling, cold sweats, shaking lasted about 8 hours. Full recovery was additional 18 hours later.

Sore and practically immobile arm starting 4 hours after injection. Treated with Advil. I could lift my arm the next day and recovered the third day. Inside of mouth felt sore and inflamed starting approximately 8 hours after injection. Lower face and lips swollen at approximately 10 hours after injection. Treated with Benadryl for 2 days. My breathing and swallowing was not effected so I did not seek medical treatment. Swelling disappeared 2 days after injection. Indigestion started 1 week after injection. Treating with occasional otc antacid. I have never had indigestion before.

waited 15 min at clinic then headed home and half way -about 10 or so later- felt his face and checks start to swell from right to left as well as facial glands. He then took 2 Benadryl at home and 20 min later felt swelling going down and had no further problems,just started to feel side effects of vaccine that night. Next day felt fine.

Patient recieved vaccine on Monday 3/29/21 around 9:30am, he started to feel itchy same day around belly button but as the week went by the rash increased (looks like bumps and no puss), looks like a hives rash some places looks worse than others and looks patchy. He also c/o bilateral swelling in hands/fingers. No c/o fever, bodyaches, chills, headache, sob. As of 4/7/21 @3:45pm swelling has subsided but the itchyness and rash is not getting better. Patient took Benadryl, and applied Triamcinolone cream, and also took Xyzal. Advised patient to continue with the Benadryl/Xyzal to help with the allergic reaction. He may also apply benadryl cream and hydrocortisone cream to help. Informed patients wife that if he experiences any fever/body aches/chills to take Tylenol or Ibuprofen but if he experiences any SOB or chest pain then proceed to the Urgent Care or ER. The brother in law is a Dermatologist which he prescribed him the Triamcinolone cream. 4/9-Follow up: Patients wife called back and stated that patient is still itchy (almost 2 weeks) but it's drying up now. She stated he is still taking benadryl and applying the triamincinolone cream. Advised to continue with the Benadryl/Xyal and benadryl cream. Will follow back up on 4/12/21.

Itchiness at the injection site developed after ~ 2 days, still persistent at day 10. Minor swelling of lymph nodes near the arm pit at ~ 5 days, reduced at day 10 but not completely gone.

Dull headache, right arm where shot was given swollen, I had a dazed-out feeling day given vaccination, had a very hard time going to sleep on the day I got the vaccine, next night I slept 10 hrs, arm is still stiff 3 days later

without warning and approximatly 5 minutes after patient recieved vaccine patient passed out and fell face first onto floor. patient was approached lying face down on floor bleeding and sounds of gurgling coming from patient patient was unreponsive. When patient was brought around and returned to conciousness patient did not know where he was or what had happened. Patients pulse was very low at 58 and dropping to as low as 39. Patient pulse did not stabilize the entire time patient was under our care. Patient had about a inch and a half laceration about eye and possible facial fracture. It was noticed that patients face was swollen when leaving with ambulance to be transported to er.

left arm started to hurt pretty bad; patient felt flushed and hot; skin was red; shivering and shaking on left side of their body; left side numb, kind of Bells Palsy syndrome; feel cold in their shoulder; cold behind left eye then from wrist to behind both eyes; left side of the body was swollen, like swollen pecks, back and chest, like they had been stung; This spontaneous case was reported by a consumer and describes the occurrence of FACIAL PARALYSIS (left side numb, kind of Bells Palsy syndrome) in a 43-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 039K20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. The patient's past medical history included No adverse event (No reported medical event). On 08-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 08-Jan-2021, the patient experienced PERIPHERAL COLDNESS (feel cold in their shoulder), ABNORMAL SENSATION IN EYE (cold behind left eye then from wrist to behind both eyes) and SWELLING (left side of the body was swollen, like swollen pecks, back and chest, like they had been stung). On 09-Jan-2021, the patient experienced FACIAL PARALYSIS (left side numb, kind of Bells Palsy syndrome) (seriousness criterion medically significant) and CHILLS (shivering and shaking on left side of their body). On 10-Jan-2021, the patient experienced PAIN IN EXTREMITY (left arm started to hurt pretty bad), HOT FLUSH (patient felt flushed and hot) and ERYTHEMA (skin was red). At the time of the report, FACIAL PARALYSIS (left side numb, kind of Bells Palsy syndrome), PERIPHERAL COLDNESS (feel cold in their shoulder), ABNORMAL SENSATION IN EYE (cold behind left eye then from wrist to behind both eyes), PAIN IN EXTREMITY (left arm started to hurt pretty bad), SWELLING (left side of the body was swollen, like swollen pecks, back and chest, like they had been stung), CHILLS (shivering and shaking on left side of their body), HOT FLUSH (patient felt flushed and hot) and ERYTHEMA (skin was red) had resolved. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. Reporter did not allow further contact; Reporter's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Further information has been requested.

Whole body became red, swollen, itchy, throat closing up, felt like I had a severe sunburn, anaphylactic allergy

symptoms: dizziness, diarrhea, mid epigastric pressure vitals : tachycardia, leukocytosis admitted for monitoring and IVF

fatigue, sinus pressure - but most troubling was swelling of Achilles tendon in right foot. Increasingly painful at night but difficult to put pressure on throughout day.

SWELLING, PAIN, GRADUALLY WORSENING. DEVELOPED AN ABSCESS OVER LEFT UPPER BACK IN SCAPULAR AREA. CT SCAN, ABSCESS INCISION & DRAINAGE & PACKING, STARTED ON ANTIBIOTICS. DIAGNOSED WITH SEPSIS ALSO. ALSO BLOOD SUGAR FOUND TO BE 400 WITH NO PRIOR HISTORY OF DIABETES

swollen lymph node in armpit of arm where injection was received (lasted for 16 days after injection), sharp burning nerve-like pain to touch down arm of injection site onset 10 days afterward. Lasted about a week from there. Felt a lot like nerve pain. Got evaluated at Urgent Care for possible shingles. Diagnosed a negative.

Swelling and numbness in the right calf as well as purple spots around it. The numbness does not diminish and the purple spots have not faded. I need not to have movement so that it doesn't bother me.

Red splotches/ hives on arms, belly, and legs. Some are slightly raised. There is no pain, itchiness, or discomfort. This happens on occasion. It is similar to the reaction I have to penicillin. It happens sometimes when I?m ill with a flu or cold, but I?m not sure if the reaction is due to the illness or OTC or prescription medication. I?m not concerned for my health. I just wanted to report the reaction.

Patient reported fevers, chills and myalgia after 1st dose of Moderna COVID vaccine 4/22. Poor PO intake and had syncopal episode on 4/24 when standing from the recliner. Initially admitted at hospital, and developed fever, leukocytosis, AKI. Transferred to other hospital for further evaluation and eventually developed acute hypoxic respiratory failure requiring intubation and mechanical ventilation, found to have new onsert heart failure with reduced ejection fraction. He is currently being evaluated for auto-immune and underlying infectious causes, with concern for glumerunephritis, cardiomyopathy and coronary artery disease. Patient extubated to NC as of today but remains in the ICU.

Swollen Lymph node on my left collar bone. DIdn't notice it for a few days but it lasted about 2.5-3 weeks. Was about the size of a large marble. I was worried about getting second dose then I noticed that people had this as a common side effect on their collar bone. I was very sleepy the day after the shot and very foggy. I didn't wake up until 10 AM and then worked until about 1230 PM then went and laid back down. It wasn't for several days until I noticed the lump on my collar bone.

VACCINE-RELATED LYMPHADENOPATHY, symptoms started within hours at mid-throat, right side only. This began to radiate pain outwards and upwards over the course of few days. By the fourth day, the pain and swelling had spread to entire jawline and neck, right side. Visit to ER confirmed periodontal abscesses, in total 3. After one week of antibiotic, symptoms returned with greater pain, spreading back to entire right neck and jawline into right ear. As of this writing, it has been 19 days since the second Moderna shot and the lymph nodes in the entirety of my right side hurt.

Moderna Covid-19 Vaccine EUA. Patient reported ear pain / sensitivity, which radiated from ear to shoulder, beginning approximately one hour after vaccination, and lasting approximately three hours. The event then recurred ten days later, and, again, lasted approximately three hours. Patient also reported lymph node swelling in the arm pit of the left arm, where the injection was given.

fatigue, no treatment, mostly resolved at 14 days from vaccine date sore throat, started bilateral but shifted to left side tonsil/throat (same side as vaccine). Pain mostly resolved at 14 days from vaccine date. swollen left axillary lymph node, discovered at day 13 from vaccine date. No treatment or diagnosis other than self-administered manual exam. As of morning of day 14, swelling is reduced but not gone.

Pt reports redness and tightening of his face, resolved by Benadryl. Next morning, pt had an episode of n/v, achiness, fatigued and SOB. Pt admitted to hospital for sepsis and cellulitis from a podiatry procedure. Pt in a state of hypercoagulability r/t to covid vaccine and sepsis. Pt advised not to receive 2nd dose of moderna or j&J.

Swelling of lower legs and hand (right side). No swelling of face. Told patient to call Docotor and goto ER.

Sunday morning (2 days after vaccine) slight pain on right palm led to discovery of swollen palm (one-third of the palm). Swelling has persisted until date of reporting. Contacted Moderna who took down information and issued a case number. Moderna stated someone from their company may or may not contact me. Indefinite as to the resolution.

ANAPHYLAXIS: Pt received his second Moderna COVID19 shot on 12Apr2021 at approximately 2:30pm. He waited the required 20 minutes to check for any adverse reaction and then left the facility to drive home. On his drive home, at approximately 3:30pm, he started feeling light headed and lost consciousness, striking a telephone pole. He was gasping and struggling to breathe, so the ambulance treated him with oxygen. When he arrived at the ER , the doctor assessed his condition and confirmed that he was experiencing an anaphylactic reaction related to the COVID vaccine and treated him with an epinephrine injection, steroids, benadryl, and nebulized albuterol.to open his airways. He remained at the ER for ~ 6 hours for observation until his blood oxygen levels increased and he was stable to be released. The car accident resulted in PT suffering a fractured sternum as confirmed via Chest CT Scan by his primary doctor. PT has no history of any allergic reaction to any medication or vaccine. Although he does have well-regulated asthma, this incident was not characteristic of any asthma-related reaction he has ever experienced.

Fever 102 F next day, lymph node on left arm pit (same arm as shot was given) swelled up about the size of a golf ball and lasted a week.

Patient developed a DVT in left calf that resulted in multiple pulmonary embolisms; patient complained of shortness of breath x 2 weeks and presented with a swollen and discolored lower leg. X-rays and scans confirmed DVT and PE's. Patient underwent thrombectomy and was on Heparin drip followed by Eliquis at home. Patient discharged from ICU after 3 days.

Oval , peanut size ball on left arm. Fever, headache , body ache , and weakness, and constipated . Had to get surgery to remove the oval ball from arm .

Day after pain in the area of my lung scar and under arm , skin rashes as well in chest, they come back and then it was fine for a while but recently in June with Heatwave 1 and currently heatwave2- I felt horrible pressure and pain in my chest and could not breath and the nebulizer wasnt helping. I got an xray and the doctor at the City Md refused to believe me that this was related to vaccine and my lung wound from a previous surgery that increases inflammation as I am now experiencing. I am asking to please help me get a cooling airc conditioner in my kitchen/ bathroom area as it is also where I will be teaching virtually hybrid schedule and only feel relieved in cool air. My school that I teach at is in some rooms adding daily heat exhaustion and I would greatly like if possible any help or treatment and or rehabiliation phyical therapy and also reexamining the area where my origial surgery was and how this can be dangerous for people taking the vaccine.

Rapid Heart Beat Blurry Vision High Fever - Approaching 2 weeks Strong Dizziness/Vertigo Rashes Week long Headaches Hard to breath Ringing in ears Deep ache/pain in leg & arm with leg swelling

1- sever fever above 38 degrees up and down. 2- developed herps libilails HSA# 1 3- left arm axillariy lymphnodes swelling.

Had manageable bodyaches but following day triggered his Migraine headaches which is what patient came in for primarily. Symptoms managed with fluids, tylenol, reglan with improvement and was subsequently discharged from the ED.

reports development of right arm redness and swellling related to covid vaccine administration. On 1/16/21, he reports having fatigue and body aches. On 1/17/21, he reported right arm redness, swelling, and warmth which increased throughout the day. He took 800 mg of Ibuprofen and ultimately sought care at a local emergency department, and was prescribed two oral antibiotics. stated the emergency room provider diagnosed the condition as cellulitis and informed patient the condition is a known side effect of vaccines. As of this writing, patient reports a decrease in redness/tenderness and no pain.

Axillary swelling on same side of vaccine administration. +some associated pain. Developed 7 days after vaccine administered.

High fever 104F with chills and sweating- has been on going since symptom on set with periods of some relief (Tylenol will bring fever down to 101 F). Nerve pain, "my nerves are on fire." It seems to be rotating through various nerve clusters. At first it was through his arms, then shifted to the back of his left leg, then the right, then down to his toes, then fingers. Joint pain, this was bad enough he buckled a couple times and fell the night of 02/05/2021 twice. Facial swelling, most pronounced on nose, lips, and chin. This started 02/05/2021 at around 10:00 AM. It has been variable in degree since it has started. Vomiting, started 02/05/2021 at around 09:30 PM. This was after a period of nausea. The vomitting has since slowed down, but not stopped.

The day after my second shot I experienced what I am assuming is a swollen lymph node along my left collar bone. It was swollen, red, and painful to touch. it is not painful to touch and some swelling has gone down and no redness. However, it is still visible and can be felt.

Received vaccination on 2/2/21 @ 0900. Immediately afterwards he said he was in excruciating pain. He reported he went to his primary care provider later that afternoon. He was examined clinically and was told that the shot was administered too high up in his arm in the Gleno Humeral Joint. He was advised to take over the counter pain medication and to call if he needs something stronger. He was given a follow up appointment on 2/5/2021 with the provider. He was told to monitor for infection in the next 48 hours and they are hoping it did not go into the joint capsule. Continued to have severe pain. Went to orthopedic specialist the next day. Admitted to hospital for pain control and steroids. MRI of shoulder inconclusive, but think severe bursitis and being treated as such. Discharged from hospital and resting at home. Arm range of motion at 80%-hoping to return to work in 2 weeks (firefighter/EMT).

Delayed reaction to the shot 8 days after. Soreness in arm hot, itchy , swollen and painful. 3 days later pain had stopped but right arm out swollen.

Lots of arm burning with rash and painful to touch at area of injection site (2/11 am) - up to 5x5"; some improvement 2/13 - now mostly resolved - light pruritus only; axillary fullness 2/11, but enlarged through 2/14 and somewhat better today.

-Age 25 dx with DM1 -12/2020 HbA1c 10% on insulin pump -2/5 second dose of Moderna vaccine (in R arm), R hip pain, resolved -2/7 R hand red/swollen, R second and third toes red/swollen -2/9 ED, given prednisone 40mg po qday and diphenhydramine for ?vaccine-related immune reaction. Afebrile, HR 101, BP 144 systolic. -2/10 Rheumatology outpatient visit, afebrile, ?acute polyarthritis of R hand and R foot, prednisone increased to 60mg po qday -2/11 ED afebrile, xrays done, 2g ceftriaxone, colchicine, doxycycline. -2/12 back to the ED. R hand more swollen. R toes perhaps improved. Admitted. -2/12 MRI R hand - "There are small effusions in the second third and fourth MCP joints. There is some subtle synovial enhancement about the MCP joints best visualized on sagittal imaging. May be a small erosion in the fifth metacarpal head. There is some additional synovial enhancement about the lateral wrist. There are some subtle enhancement peripheral to extensor tendons at the wrist consistent with tenosynovitis. No other abnormality is apparent." Given 500mg IV methylpred and 80mg po qday prednisone. Initially improved in first 24hrs and then edema returned. Discharged. No antibiotics. No markers for infection. -2/18 outpatient Rheum. R hand still swollen. Tried 3rd MCP join aspiration without fluid. Rapid taper of oral steroids as not helping. Had steroid injection R extensor wrist and 3rd MCP joint. Acute inflammatory polyarthritis affecting right hand and right foot. ?due to or triggered by COVID vaccine. Patient without h/o similar events/symptoms.

Fever, fatigue, low grade fever, swollen lymph node in arm pit and neck. Heart SVT, rapid heart beat 48 hours later

Rashes, itching and swelling welks on thighs and arms. Rashes covered most of the front of my thigh and caused some muscles soreness and pain

Extreme fatigue, Chills, Nausea, Body aches Headache HUGE painful swollen lymph nodes (right armpit, near injection site) Began Mar 11 (day after 1st dose of vaccine). Mostly ended after Mar 12, except painful swollen lymph nodes remained until Mar 16

3/12/2021: Fever 100.1F; lasting from 2:30pm through 3:30pm; elevated temp of 99.2-99.6 until 3/15/2021 3/12/2021: Chills ~8pm until ~2am on 3/13/2021 nasal congestion 3/13/2021 7:30am-11:00am elevated pulse ~115bpm sporadically from 3/13/2021-3/15/2021 swollen neck glands/throat tightness 3/14/2021 8pm-11pm numb lips & tongue 3/15/2021 2pm-3pm

No reaction for first 4 or 5 hours, increasing in pain until left arm and shoulder became immobilized. Severe pain when touched, and slowly backing off after full 48 hours. It?s been 10 days and Left arm shoulder has about 85% mobility. Swelling in armpit also still present but almost gone. I have a lock jaw kind of sensation still lingering as well. No infection detected at injection point. Worried for dose two.

Swelling inside collar bone area on side of injection. Possibly lymph node. First time noticing swelling is approximately 7 days after 1st injection. Over the next 3 weeks, swelling decreased to almost normal until 2nd dose. After that, swelling was noticed approximately 48 hours later and correlated vaccine with swelling. Between the 1st and 2nd dose, I visited MD, Physical Therapists, Massage therapist. Other symptoms included popping of collar bone when shrugging shoulder.

Diagnosed with cellulitis; Diagnosed with sepsis; Temperature 102 degrees F/104 degrees F; Chills/Shivering; Discomfort; Difficulty breathing; Felt cold; Not feeling good; In a lot of pain; A spontaneous report was received from a pharmacist concerning a 44-year-old, male patient who received Moderna's COVID-19 vaccine (mRNA-1273) and developed cellulitis, sepsis, temperature was 102 and 104 degrees F/fever, dyspnoea/difficulty breathing, feeling cold, malaise/unwell, pain, discomfort and chills. The patient's medical history was not provided. Products known to have been used by the patient, within two weeks prior to the event were not reported. On 11 Mar 2021, the patient consulted wound care for his foot and was told to be fine. On 13 Mar 2021, prior to the onset of the symptoms, the patient received their dose of two planned doses of mRNA-1273 (batch number: unknown) for prophylaxis of COVID-19 infection. On 13 Mar 2021, within eight to ten minutes, after vaccination patient felt cold .The patient's temperature was noted to be 102 degree Fahrenheit. Also, patient reported a lot of pain and discomfort. Patient also complained about chills, cold and shivering and he was given an orange juice and blanket after five to ten minutes by the pharmacist. Pharmacist called patients wife and by that time patient developed breathing difficulty. Patient's temperature was raised to 104-degree Fahrenheit by that time and was taken by the emergency medical service to the hospital. The patient was hospitalised. On 16 Mar 2021, after 2 days, patients wife reported to pharmacist that the patient was diagnosed with sepsis and cellulitis and was given two antibiotics. The events sepsis and cellulitis were considered as serious (medically significant). The patient's wife reported that the patient was about to have an amputation in this past weekend. Treatment for the event included two unknown antibiotics. Action taken with mRNA-1273 in response to the event was unknown. The outcome of the events cellulitis, sepsis, temperature was 102 and 104 degrees F/fever, dyspnea /difficulty breathing, feeling cold, malaise/unwell, pain, discomfort and chills were considered to be unknown.; Reporter's Comments: Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.

Less than a week after the shot i discovered a lump on the left clavicle area measuring 0.6 x 0.6 x 0.7 cm via ultrasound. A second hypoechoic area was found measuring 0.6 x 0.3 x 0.6 cm. I also had discovered a small lump on my left ear. All of these condition are on the same side of the body as the injection site.

Lymph nodes in left and right armpits swelled (5 in left, 2 in right). One erupted to the surface expelling pus and blood.

Swelling, inflammation, itchiness at injection site. swelling of submental lymph node. symptoms started 5 days post-injection, peaked at 7-8 days post-injection. subsiding by 10 days post injection. In all, minor "Moderna-arm" side effect, but wanted to report anyway. Submental lymph node swelling was maybe worth documentation.

Swollen and very painful lymph node on left armpit area & fever of 101°. After receiving the vaccine 4 days prior. Had to go to urgent care facility.

The day after the vaccine the patient's arm swelled around the tri-cep area down to the elbow. It felt squishy like it was fluid filled. This lasted for about 1 week. He also experienced fever, chills, and bodyaches requiring him to miss work.

About 5 days later I had intense swelling and itching all over my right thigh. It spread to other parts of my body before getting a steroid shot and prednisone. About a week later it came back.

Pain in injection site was first effect. The next morning body aches and fever began. Followed by Nausea and swollen and tender right arm in arm pit and severe headache. The arm pit hurts the worse. No outcome as of yet

sharp pain left chest. chest x-ray revealed pulmonary effusion in left lung. CT with radioactive dye ruled out Pulmonary Embolism. Swollen lymph nodes also noted in left armpit

He says he got his second COVID shot (Moderna) on Saturday and says his lymph nodes in his neck and armpits got swollen and sore which was similar to when he once got bit by a black widow. His energy has been low, and he has been feeling dizzy with a fever on Sunday and Monday. He has not been able to go back to work since the shot. He says that on Sunday he wasn't able to get out of bed. He got the shot because his mother's nursing home required it in order for him to see his mother.

5/1/21: Patient woke with chest pain, elevated respiratory rate, nausea, and sweating. Recognizing symptoms of a heart attack, the patient presented to the emergency room at 5:30am. ECG normal, Troponin at 2.1 at presentation, continued to increase to 4.6 prior to being taken to Cath Lab. Coronary angiography showed no occlusion; patient admitted to telemetry unit for continued monitoring; discharged following day with order for cardiac MRI. Outpatient cardiac MRI conducted 5/5/21 revealed myocarditis. Treatment with beta blockers (Metopolol Succinate 25MG QID) and anti-inflamatory (indomethacin 25MG TID) with direction to avoid exercise. Light yardwork on 5/22 resulted in patient feeling "racing heart".

14 hrs after the vaccine, developed flu symptoms. beginning at 14 hrs, started taking temperature and did so every half-hour. At hour 18, temp was 100.9, 30 min later, 101.5, 30 min later, 102.0, 30 min later, 102.7. when temp reached 1019, spouse began to administer cold-wet cloth to heated areas, e.g., stomach and lower back, spouse continued until for 45 min, until temp dropped to 101.5. checked temp every hour after that, until dropped below 100.0. Temp returned to normal roughly 25 hrs after vaccine administration. 68 hrs after vaccine administration, developed cold sores. Normally, the cold sore would manifest in an area no more than 5% of upper lip area, After the COVID vaccine, the cold sore covered 35% of upper lip area, and lasted about 24 hours longer than it normally would. lasted 5 days vice 3 - 4 days, normally.

Patient developed episode of diarrhea shortly after 1st shot in series, this was followed by lower extremity swelling and mild dyspnea on exertion, that quickly exacerbated after the 2nd shot on 5/15/2021, that resulted in severe dyspnea on exertion, severe lower extremity swelling with approximately 25 lb weight gain, orthopnea and hemoptysis. Patient reported temperatures of 99.2 F to 99.8 F. Outside CT chest abdomen pelvis angiogram showed moderate to large acute segmental/subsegmental pulmonary emboli with trace right heart strain and right lower lobe pulmonary infarction, moderate right pleural effusion, acute splenic vein thrombosis with extension to the proximal portal vein and associated splenic infarcts, bilateral renal infarcts, and evidence of portal hypertension. He was transferred to the Hospital for further management. Upon presentation here he was tachycardic but with stable blood pressures and requiring up to 5 L by nasal cannula. Initial laboratory studies were notable for WBC 21.0, INR 1.8, D-dimer 11653, NT pro-BNP 17684, troponins 603 to 579 to 574, CRP 127. He was started on a heparin infusion. He was admitted to the MICU for further management. Bedside ultrasound demonstrated reduced biventricular contractility. He was given two doses of 40 mg intravenous furosemide with about 3.5 L of urine output since admission (net negative 3.1 L). His oxygen was weaned to 1 L by nasal cannula. Lower extremity venous and arterial Dopplers were negative. Subsequent imaging demonstrated a transperineal inferior infarct with akinesis of the inferior septum, inferior and inferior lateral walls with apical and mid ventricle akinesis secondary to a complete occluded RCA. moderate pericardial effusion without tamponade noted. Upper extremity ultrasound demonstrated acute DVT in the lower right IJ, innominate, subclavian and proximal axillary veins. MRI venogram was negative for clots, but multiple acute and subacute enhancing infarcts within all 3 vasculature distributions consistent with embolic etiology were noted. TTE showed of mural thrombus along the septal and inferior walls of the LV apex, severely enlarged left ventricle with EF of 20%, severe hypokinesis. Patient was aggressively IV diuresis, with improvement in respiratory status. Maintained on high-intensity heparin for pulmonary emboli, DVT, and diffuse arterial and venous thrombosis. He was bridged to warfarin. Patient was prescribed LifeVest for primary prevention. Started on beta-blocker and ACE-inhibitor given EF. Patient planning on discharge 6/5-6/07, outcome pending.

A fast heartbeat Dizziness and weakness Injection site pain Tiredness Helada che Muscle pain Chilla Joint pain Náusea Feeling unwell SEOLLEIM lymph nodes

Raised red circle around injection site. Swollen, itchy, warm to touch. Started the size of a half dollar expanded to the size of an orange by day 3, subsiding in size on day 4.

ON FRIDAY, 30 APRIL 2021, ABOUT TWO WEEKS AFTER GETTING THE FIRST COVID VACCINATION, I NOTICED A NUMBER OF SMALL PATCHES OF ECZEMA FLARING UP ON MY ANKLES, ELBOWS, AND HANDS. ON MONDAY, 3 MAY 2021, I VISITED MY GENERAL PRACTITIONER ABOUT THE ISSUES WITH MY SKIN AND HE WONDERED IF I HAD STEPPED IN POISON IVY OR POISON OAK. I EXPLAINED TO HIM THAT I HAD NOT BEEN HIKING AND THAT WE DO NOT HAVE POISON IVY OR POISON OAK IN OUR YARD. HE PRESCRIBED A .5 PERCENT CLOBETASOL STEROID CREAM. THE VISIT TOOK TWENTY MINUTES AND I WAS CHARGED $98.95. ON FRIDAY, 14 MAY 2021, AT 3:00 PM, I RECEIVED THE SECOND COVID VACCINATION. BY 9:00 PM, I NOTICED TINGLING AND NERVE PAIN ON MY HANDS...

I felt my body ache initially then fever sometimes. Headache. I was developing Rashes on my body I went to urgent care and they took a blood sample. At 8:30 PM I got a call from Dr the I have to visit urgent care immediately for a few more tests. Skin: Positive for rash (noticed rash on the trunk and abdomen yesterday. papular rash ). Neurological: Positive for weakness (feels tired and fatigued for last 2-3 days.). Negative for dizziness, tingling, numbness and loss of balance. Psychiatric/Behavioral: The patient does not have insomnia.

It was an hemorrhage with broken veins; He had his right feet hot, swelling and purple; He had his right feet hot, swelling and purple; He had his right feet hot, swelling and purple; This spontaneous case was reported by a consumer and describes the occurrence of HAEMORRHAGE (It was an hemorrhage with broken veins), FEELING HOT (He had his right feet hot, swelling and purple), PERIPHERAL SWELLING (He had his right feet hot, swelling and purple) and SKIN DISCOLOURATION (He had his right feet hot, swelling and purple) in a 44-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. No medical history was reported. In April 2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced HAEMORRHAGE (It was an hemorrhage with broken veins) (seriousness criteria hospitalization and medically significant), FEELING HOT (He had his right feet hot, swelling and purple) (seriousness criterion hospitalization), PERIPHERAL SWELLING (He had his right feet hot, swelling and purple) (seriousness criterion hospitalization) and SKIN DISCOLOURATION (He had his right feet hot, swelling and purple) (seriousness criterion hospitalization). At the time of the report, HAEMORRHAGE (It was an hemorrhage with broken veins), FEELING HOT (He had his right feet hot, swelling and purple), PERIPHERAL SWELLING (He had his right feet hot, swelling and purple) and SKIN DISCOLOURATION (He had his right feet hot, swelling and purple) outcome was unknown. Concomitant product use was not provided by the reporter. The patient went to the hospital and was told that it was an hemorrhage due to broken veins and did not have clots. Based on the current available information and temporal association between the use of the product and the events, a causal relationship cannot be excluded. No treatment information was provided. The patient received both scheduled doses of mRNA-1273 prior to the events therefore, action taken with the drug in response to the events was not applicable. Based on the current available information and temporal association between the use of the product and the events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the events, a causal relationship cannot be excluded.

I developed a DVT in my lower left leg, which I noticed from the swelling, warmth and pain. Then, a few days later, on a Sunday so my Dr's office was closed, I started having extreme difficulty in my breathing. I went to the ER and, after having multiple testing, was diagnosed with the DVT and a PE in each lung (almost to the point of full blockage). I was kept in the hospital overnight so they could monitor my breathing to be sure I wasn't stopping breathing throughout the night. I'm now on blood thinners for life.

Patient presented to the ED and was subsequently hospitalized for severe sepsis with lactic acidosis within 6 weeks of receiving COVID vaccination.

Psoriasis on gluteal areas that has been present for almost 2 months. Lymph node on right neck area is swollen for almost 2 months. Skin on chest, back, and stomach area is itching constantly.

Guillain Barre Syndrome; 7/18/21 gabapentin started 7/19/21 IVIG (Privigen) 30g IV for total of 5 days 7/20/21 symptoms worse 7/21/21 -7/23/21 symptoms gradually improved 7/24/21 Patient is doing better. Strength continues to improve. Tingling in feet resolved. Minimal in fingers. No other complaints. discharged from hospital.

Patient presenting approx 45 minutes after injection with facial swelling to eyelids and upper face. Also had an associated pruritic rash on right upper back region. No swelling to mouth, lips or tongue. No SOB or wheezing. Symptoms improved (decreased swelling) with 50mg PO benadryl. Was discharged after monitoring for 2 hours. Provided rx for epi pen upon discharge.

I noticed a lump above my left clavical. Not sure if it is a swollen lymphnode. It is painful to palpation and still present.

Nearly two weeks after injection, I now have a 4 inch diameter circle of redness with slight swelling and itchy. I noticed it after showering two days ago. It almost looks like a localized allergic reaction but it did not appear until 2 weeks after the shot. It is slightly warmer to touch than the rest of the area but it is not painful at all. I had similar markings plus moderate pain around the injection site1-2 days after the shot but they quickly dissipated. I am not sure if this should be reportable or not but I was a little concerned considering the amount of time that has passed since the shot and considering I am due for my second shot in a couple of weeks.

Moderna COVID-19 Vaccine EUA: Swelling/Closing of my throat, swelling of my left hand (the hand on the injection arm), body itching, chills, soreness at injection site

patient (medical director of Nursing Center) reported on 1/25/21 that after receiving the first dose on 12/28/20, two weeks later he developed two areas with swollen lymph nodes. Both areas occurred on the left arm which is the arm in which the first COVID19 vaccine was administered. The swollen areas lasted one week then resolved.

I didn't have any adverse affects until 5 days after I received the vaccination. Early in the afternoon on Wednesday 1/20 I noticed that my lymph nodes in the armpit of my left arm and on the left side of my neck were swollen and sore. This worsened as the day went on. I also noticed a pimple had formed and came to a head in the exact spot of where the needle stick had been. It "popped" that day and a small amount material came out. My lymph nodes have remained sore and swollen since 1/20. On the 7th day after (1/22) I noticed a couple of smaller, dime sized red blotches/rash on my left shoulder and left side of my neck. I also noticed that the injection site on my left shoulder was sore, swollen and hot to touch. On the 8th day (1/23) I noticed that there were more of these dime sized red blotches/rash across both shoulders, my back and a small area in the center of my chest. It continues to be like that as of today (1/25). On the 9th day, (1/24) starting just after noon, I began to feel poorly. Achy and just generally not very good. I had a few bouts of diarrhea throughout the afternoon. I also had a pretty strong headache when I awoke on the morning of the 24th. Today, (1/25) I awoke again with a headache although it was not as sore as yesterday. I don't feel great today, but I do feel better than I did yesterday. The rash looks the same and my lymph nodes seem to be slightly less swollen and less sore.

The patient did not have any adverse reactions during the 15 minute observation, nor any reported the day of the vaccine. Between his COVID diagnosis and the second vaccine, he had serval documented complaints of nausea, dizziness, body aches. The patient had a virtual visit on 1/21/2021 for dizziness, nausea and fever. At this time, these symptoms had been persistent for one month according to his medical records. Patient later presented to the Urgent Care for with a fever of 103.1, rigors, nausea and cough. Patient admitted to hospital for sepsis.

2 days after second Covid Vaccine dose, developed a "softball" sized swollen lymph node in the armpit of the left arm, same arm that vaccine was administered. Was severe for 3 days, can patient could not even put his arm down to the side all the way. Resolved by 1/27/21

I noticed swelling in my right arm pit the day after I received the shot. The swelling is still there this morning.

More than 48 hours after receiving the first dose my lymph nodes near my left clavicle swelled up and became very sore. That same night, more than 64 hours after receiving the first shot, I had a intense fever for three hours and was able to break the fever. I did have COVID-19 back in July 2020 with 2 confirmed positive tests.

Began with severe fatigue and transitioned into severe shaking, body chills, aches that stayed for a prolonged period. In the course of trying to bring warmth to the body, I showered and ended up having severe vomiting. The body aches, fatigue, and overall sickness stayed with me for over 48 hours. Two days post vaccination, my left arm was swollen with severe redness. I am still struggling with fatigue and body aches (4 days later) but have regained mobility and strength.

Moderna COVID-19 Vaccine EUA The evening after the shot, my arm was extremely sore. Over the course of the next day, I developed a moderate to severe headache along with swelling in the lymph node under my right arm in the arm pit. By the second day after the shot (March 3rd, 2021) all symptoms except some swelling in the lymph node had resolved.

Swelling in body. Particular face and eye. One one is completely shut. Lots of discomfort and inability to work. Can send a picture. It has not started healing yet. Swelling is still very high.

the patient had a swollen armpit/lymphnode area after receiving the moderna vaccine. he said it was painful (likely due to the swelling and location) and has only just started to go down after the 3rd day. i instructed him to follow up with his doctor and determine what course of therapy and whether or not to complete the series.

1 minutes post inoculation: Tachycardia with HR 160BPM & left arm swelling. Pt states feeling "generally unwell." Anxious mood. Meds administered during ED visit: Sodium Chloride 0.9% bolus 1L IV; famotidine 20mg IV; diphenhydramine 50mg IV During ED visit VS: BP 123/76, Temp 98.2F oral, HR 84, RR 16, SpO2 100% on RA.

Flu like symptoms. Felt foggy no energy. Tingling on neck and head and face felt swollen and hot but was visibly normal. **** I am having a screen reaction on injected arm that strain the day after injection and has continued to spread. As of 4-16-2021 at 10:30 Pm it is the size of a tangerine. Red , warm to touch with undefined boards.

Pt received his first Moderna vaccine on 2/25/2021. 3 days later he developed significant oral pain located on the roof of his mouth, back of mouth and throat. He presented to clinic about 1 week later for evaluation. There were no obvious signs of trauma or infection at the time. He followed up with this Dentist and it was suggested he likely had a chemical burn secondary to citrus foods. He followed up with another provider and was treated with a 3 day course of an antiviral medication for herpes without any change in symptoms. He hasn't had oral herpes before, but has had shingles. He received his second Moderna vaccine on 3/25/2021 and 3 days later developed significant throat pain and swelling in his neck glands that was visible to him. His symptoms improved slightly, but have never completely resolved. He has had what feels like a dry sore throat for 7-8 weeks and intermittent white patches in the back of his mouth. He has no history of or active allergy symptoms. Was treated for oral candidiasis on 4/19/2021, but it's unclear if his vaccine triggered these symptoms.

Extremely swollen lymph nodes on left clavicle. Huge swollen lymph node can be seen and felt through the surface of the skin on the left shoulder/neck area. Additional swelling and discomfort in left armpit and left calf. Painful to move arm. General fatigue. This occurred 4-5 days after injection. The swelling occurred suddenly over night. Four days after symptoms occurred, swelling and pain has subsided, but is not completely gone.

PATIENT STATES SWELLING IN ARM AND HAND, UNABLE TO MOVE OR ROTATE ARM. SYMPTOMS ARE RESOLVING AS OF SUNDAY 4/25/2021 AT ABOUT 12 NOON.

Patient stated he started having trouble breathing and became shaky about 5 minutes after the vaccine was given. An epipen, gatorade, and an icepack were given to the patient, and he immediately started feeling better.

Pt reports on April 15th he began feeling fatigue, fever, aches, lip swelling, and soft palate swelling that lasted two days. Pt said he could not sleep laying down because his soft palate blocked his breathing. Pt reports taking an antihistamine and feeling better after 4 days. Pt showed photos of lip swelling, and he reported it to his health care provider. His health care provider sent an email that recommended not receiving the second dose of Moderna. However, pt was automatically scheduled from his first visit to get second dose, and pt showed up to site to discuss it and showed this vaccinator the email and photos and described this course. This vaccinator did not administer second dose of vaccine and recommended discussing alternatives with MD.

Severe fatigue, low grade fever, extreme muscle pain, swollen lymph nodes, bruising, constant headache, brain fog

fever up to 102.8, cough, tired, sore throat, chills, sweats that soak sheets, puffy face, phlegm stuck in throat

The evening of the 2nd dose, I had a fever of 100.4, the next day both my sciatic nerves felt like they were on fire. I couldn't even type an email, my hands and fingers hurt so bad. Strong fatigue, nauseous, headaches. On the Feb of 17th, my lymph nodes got swollen and they are still swollen. My head was light headed. Lymph nodes were so swollen in my arm pits that I had to lift my arms above my head to breathe. Experienced high blood pressure

Jan 15 – Moderna Shot #1 – no side effects. Feb 12 –Moderna Shot #2 – Side effects: fever, malaise, fatigue, site injection pain. Feb 13 - Side effects: fevers 99.2-100.4, body aches, lethargy Feb 14 – Side Effects: morning fevers, midday and afternoon felt like all nerves were on fire specifically the sciatic. Pain radiating down arms and it hurt to type email to (professors at ) Feb 14-17 – Side effects: nausea, mental fog, headache, fatigue Feb 18 – Side effects: (added to already listed above) lymphedema and swelling in ankles and feet. Feb 28 – side effects were still persistent, and breathing had worsened, so I sought out medical help.

patient face got swollen around 6 pm on 07/19/2021. He feels numb on left side of face and this morning on 07/20/2021 around 5 am his eye almost was shut closed due to swelling. Now swelling got better. Still he feels numb on his face.

Vaccine was not administered Intramuscular by RN administering it. It was administered into the shoulder joint of the left arm. Approximately 6 hours later, severe pain, unable to lift arm and shoulder, tingling in left arm and hands. Progressed to very limited movement of left arm and unrelieved pain. Treatment sought at ER where diagnosis was traumatic hemmorhagic bursitis from vaccine needle.

Dizziness flushing on L side, numbness through teeth and lips, swelling under L eye, L arm swelling, Narrative:

pt after injection had pain in injection site with tingling down to the fingertips. Pt stated next day he felt nauseas w/ swelling of the right lymph nodes and hot/cold flashes with vomiting. pt also experienced body aches and fatigue w/ rapid heart beat and sore throat, cough and lost his voice.

Very painful swelling at injection site, followed by redness down the arm extending about 4-5" from the injection site lasting for over 48 hours, headache began about 3 hours after and subsided about 36 hours later after taking NSAIDS ibuprofen and aspirin, fever-like chills began about 5 hours after injection and lasted about 36 hours later. Lymph node in the armpit of the injected arm began swelling after about 36 hours after injection. Still tender and swollen as report is being written. Extreme fatigue and body aches, flu-like symptoms began about 3 hours after, were intense for about 30 hours, and then disappeared after 48 hours.

*vaccine lot # same as prior lot number on same individual. Resident seen in medical clinic in follow up to ED visit this weekend, dx with vaccine reaction, likely due to prior COVID-19 infection. He reports that he developed myalgias, chills, nausea, abdominal cramping, and chest discomfort onset about 12 hours after receiving his Moderna COVID-19 vaccination on 1/29/2021. Due to the severity of his s/s that did not resolve with intervention here and chest discomfort, he was transported to the local emergency department per on-call provider. Per record review, CBC and comp met in the ED 1/30/2021 unremarkable with the the exception of t. bili 1.3. Mg. 1.7. CBC: WBC 11.0, platelets 135, abs neut 9.9, abs lymph 0.5. CKnormal 106. unremarkable. No other diagnostic testing was ordered. Resident reports that his symptoms persisted on and off to some degree through the weekend and now have completely resolved. He has noticed a red rash where adhesive tape was at his IV site. No other rashes. At no time did he report oropharyngeal edema, hives, or SOB. He was treated with ketorolac and IVF in the ED. ROS: otherwise neg. PE: Const: NAD. Neck: supple. Resp: CTAB, no increased WOB. Cardiac: HRRR, no murmur. Integumentary: erythematous patches to R AC area. No drainage or bullous lesions. A/P: vaccination reaction, resolved. Resident has been advised that this was not an allergic reaction and that he is still able to take the second dose in the series, though he may have a similar reaction. Report in VAERS. He understands he has the right to refuse the second dose. Contact dermatitis: short course topical hydrocortisone. Routine labs and f/u in clinic. He has been advised to promptly report any new or worsening symptoms.

About 1-2 days following 2nd dose, patient noticed a collection of fluid under left and right axilla. Left side more pronounced that right. Patient reported to endocrinologist during in-office visit. Patient was placed on Levaquin. Levaquin began on 2/10/22.

Localized acute left axillary lymphadenopathy. Also expiratory wheeze, intermittent non-productive cough.

Angioedema day after 2nd shot developed a swollen red right 2nd digit , seen by er dr next day worse was sent to rheumatology for consult, next worse sent to er was evaluated and sent home , at 2 am next day 2/12 was admitted to hospital with worse Narrative: day after 2nd shot developed a swollen red right 2nd digit , seen by er dr next day worse was sent to rheumatology for consult, next worse sent to er was evaluated and sent home , at 2 am next day 2/12 was admitted to hospital with worse s/s

On 2/7/2021 approx 8 PM noticed some tightness of the right arm at the injection site. On 2/8/2021 in the afternoon some swelling and continued "tight skin" of the right bicep was noted. On 2/8/2021 approx 9:30 PM noticed some "flu-like" symptoms and "poor dexterity" of right arm. Flu-like symptoms lasted until 2/9/2021 but "poor dexterity" and pain of right arm continued through 2/10/2021. On 2/9/2021 noticed swelling of the lymph nodes in the right armpit area, described by individual as "golf ball" size. Swelling increased on 2/10/2021 to include right side of chest. Pain was noted in the pectoralis and right side of back. Individual self-treated with motrin and ice for a few days. Individual did not seek medical care. Individual did not require hospitalization or doctor visit. Individual denied that swelling/pain interfered greatly with quality of life or activities of daily living. Individual did not report symptoms to Medical Clinic until >10 days after symptoms began. At the time of report individual states that flu like symptoms and pain have completely resolved. However, individual still reports some mild swelling (reports improvement of 80-90%).

Pt c/o tennis ball diameter sized lump in his left armpit (same side as the shot) about 36 hours after the Moderna immunization. Pt took OTC ibuprofen to reduce swelling and pain, which did help (about 50% reduction) He called the pharmacy to report the adverse effect on 2/26 and I advised him to contact his PCP to evaluate the lump.

About 30 mins after the injection I was itchy all over for the last two days. I took Benadryl to help with the itching. My left shoulder is still a little swollen but the pain is going away. I am not itchy today. I just wanted to make note of how itchy I was as I could not find any information on this kind of side effect.

Moderna COVID-19 Vaccine EUA Very itchy skin with circular blisters and other rash appeared 1 week after vaccination. On back, shoulders, and legs. Extremely itchy and may bleed if scratched. Swollen feet appeared a few days after onset of rash, including swollen, red toes that are sensitive to touch and feel hot. Patient does have occasional gout and guttate psoriasis, however, no symptoms reported prior to vaccination. Patient has no fever.

Swelling around the base of the neck (left, right and front) and up the sides of the neck; initially treated with heat/cold therapy and ibuprofen; no impact on the swelling; visits to the primary physician, ER and referral to ENT all unable to explain or alleviate issue

body aches, chills, and stomach ache, fatigue, headache, nausea, mild voice loss, mouth sweats, ear-ache, red eyes, swollen lymph

Vaccine administered on March 10, 2021. On March 17, 2021 around 7:00-8:00 PM I noticed a subcutaneous lump, a little swelling, redness, and a little itching. On March 18, 2021 the symptoms remain the same. No treatment done.

On 19Mar21 at 8:30 am EST noticed A burning sensation and small rash on the left side of neck. On same day in the evening noticed left supraclavicular LN the size of a walnut. The node is not painful or sensitive to the touch and is currently ongoing. Have no other symptoms except pain at the injection site the second day after the vaccine administration.

Client reported body aches, weakness, low grade fever, and that he slept for 15 hours. He states that 24 hours after receiving the vaccine he noticed a golf ball sized hard and painful area in his left axilla that lasted 3-4 days.

Hives and swelling of left are that started about 3 hours after my shot and lasted for about 3 hours. I was at work so I had no access to any allergy meds

Severe body aches, fever, tachycardia, leukocytosis resulting in admission for observation on 4/3/2021. Patient just admitted inpatient at the time of report.

Inflammed, tender, painful lymph nodes on right side of body, facial drooping, constant eye watering, difficult to close mouth and to speak clearly, challenging to shut eye.

Extremely swollen, hard and painful lymph nodes in left arm, left pectoral, under left clavicle/first rib; extremely swollen tongue and gums; hives across left shoulder, neck, chest and abdomen - all persisted for 5 days

After 5 mins of getting the 1st shot I felt an allergic reaction little bit hard to breathe and hot flash. I told the pharmacist and was advised to stay an extra 10 minutes. I left the Pharmacy and proceeded to the store and then home. Over the next 1.5 days I felt a sort of brain fog, my arm puffed up red about the size of a half dollar. The brain fog went away and then for the next 2-3 days my body felt like I was coming down with a cold. I seemed to feel better after that initial period until 3/24 when while driving a hot flash came over me and the next day I was again in a type of brain fog. For the next two days I tried to just deal with the brain fog but started to notice on the right side of my neck a feeling of constriction, with abnormally high blood pressure. I went to the hospital ER and the completed a CAT scan of my brain and neck, blood work and urine work up with no evidence of why my neck was feeling constricted and high blood pressure. The symptoms continued and on 4/1 my blood pressure spike to 168/93 and I again went back to the hospital ER and spent the night. I was having heart palpitations, anxiety and very high blood pressure. The hospital this time completed more bloodwork, MRI of my brain and neck and an Eco-cardiogram. I am now on 3 blood pressure and heart medications and have no diagnoses of why my blood pressure and heart rate are so abnormal. I am very healthy and exercise daily and have never encountered this and my BP has always been extremely good.

I have not been sick all year. About 12 hours after the shot, I had a fever, extreme pain and moderate swelling in left arm. Nausea. 24 hours after vomited. Extreme fatigue, slept 13 hours straight. 48 hours still fever and fatigue but improving. 72 hours, fever and nausea gone, but still fatigued. 96 hours later felt completely fine. ..... But here is where I find it very strange. At 120 hours after, my 10 year old daughter develops the exact same systems. She DID NOT receive any vaccination. She develop a fever and vomitted approimately according to the same time frame I did. I find this extremely strange considering we have been very viligant about wearing masks outside our home. We asked around and we do not know of anyone who has had the flu nor come in contact with someone who had the flu. I find it extremely bizarre that my whole family has not been sick all year and then 12 hours after I get the vaccine, I get sick and throw up and 4 days later my daughter also gets sick and throws up. From what I understand, this might just be a bad coincidence, but I felt I needed to report it. Thank you.

Red and swollen fingers on both hands; they were sore because they were swollen. My arm was sore at the injection site. Muscle soreness when I raised my arm above my shoulder. If I was going to examine someone for a rotator cuff injury - with the arm above that is where the soreness was. Nurse practitioner took picture of my hand that first day and the next day Dr looked at it. I had these symptoms for two weeks. My fingers are still kind of sore now. I had to try a few things to get the ring off my finger but otherwise no treatment.

I was vaccinated on 4/18/2021 at 12:10pm. Within 6 hrs, I feel very cold, severe headache, tiredness, body aches and fever till next 48 hours. I took Tylenol and I feel much better on 3rd day morning (Wednesday). However, on Thursday, I feel throat soaring. I took Claritin and throat soreness stopped. On Friday, I feel little gland swelling on right side neck and on Saturday the swelling is bit more prominent. While swallowing food and drinking water, I am feeling awkward in neck.

Spoke to Pt who states left arm swelling and pain 2 days after receiving second Moderna Covid vaccine on 4/21. Pt states swelling has improved but still having left arm tingling and discomfort. Pt states has only taken Tylenol with minimal relief of pain.

There was itching and swelling in arm couple of days after shot. After nearly 1 week there was a increased itching and swelling in the same arm. Also a little fatigue. This lasted for 3-4 days.

I began to have swollen lymph nodes which caused a sore throat. It gets better, but then returns at times. Seems to get better when I brush my teeth 2 times a day. Sometimes I take Turmeric to decrease inflammation.

Pain and swelling in left arm about 4 hours after IZ. Since IZ has experienced numbness, tingling, inability to move arm for a few hours at night on 5/13/21, 5/18/21, 5/19/21 in left arm, experienced same symptoms in right arm on 5/21/21. Reports has had full body aches, primarily focused in arms/legs off and on since IZ date.

Patient presented to the ED and was subsequently hospitalized for tongue mass and facial swelling within 6 weeks of receiving COVID vaccination.

On day 3 after the second injection, patient exhibited swelling in left index and pointer fingers Metacarpophalangeal joint and described stiffness and pain in his left Metacarpophalangeal joint, Proximal interphalangeal joints and Distal interphalangeal joints. With the severity the greatest at the Metacarpophalangeal joints and radiating down the finger joints to less severity at the Proximal interphalangeal joints. The swelling subsided within a two week period, but the patient is still experiencing pain in the joints as well the patient exhibits a rash across the knuckles of the left index, pointer and ring finger with the index exhibiting the most sever manifestation and the ring finger the least. In the past week the pain has radiated into the left elbow and the patient is unable to extend the elbow and make a fist without experiencing excruciating pain. On 6/12 rash symptoms began mirroring, with less severity to the right index and middle fingers joints.

Vaccine has been calcified; Might develop sepsis; Night sweat; Cannot sleep; Cannot raise his arm pass his shoulder.; Injected the first dose about 2 inches high and they inject it in his shoulder socket; Shoulder pain / His shoulder really hurts.; This spontaneous case was reported by a consumer and describes the occurrence of SEPSIS (Might develop sepsis) in a 46-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 043B21A and 035C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. The patient's past medical history included Shoulder operation and Knee operation. On 14-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 12-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 14-Apr-2021, the patient experienced VACCINATION SITE CALCIFICATION (Vaccine has been calcified), SEPSIS (Might develop sepsis) (seriousness criterion medically significant), HYPERHIDROSIS (Night sweat), INSOMNIA (Cannot sleep), VACCINATION SITE JOINT MOVEMENT IMPAIRMENT (Cannot raise his arm pass his shoulder.), INCORRECT ROUTE OF PRODUCT ADMINISTRATION (Injected the first dose about 2 inches high and they inject it in his shoulder socket) and ARTHRALGIA (Shoulder pain / His shoulder really hurts.). The patient was treated with PARACETAMOL (TYLENOL) at an unspecified dose and frequency and NAPROXEN SODIUM (ALEVE) at an unspecified dose and frequency. At the time of the report, VACCINATION SITE CALCIFICATION (Vaccine has been calcified), SEPSIS (Might develop sepsis), HYPERHIDROSIS (Night sweat), INSOMNIA (Cannot sleep), VACCINATION SITE JOINT MOVEMENT IMPAIRMENT (Cannot raise his arm pass his shoulder.), INCORRECT ROUTE OF PRODUCT ADMINISTRATION (Injected the first dose about 2 inches high and they inject it in his shoulder socket) and ARTHRALGIA (Shoulder pain / His shoulder really hurts.) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, X-ray limb: abnormal abnormal (abnormal) The X-ray showed that the vaccine has been calcified in his shoulder socket.. For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments. Treatment was not provided. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

I had injection site pain . I woke up the next day with chills, body aches and pain, chest pains, heart palpitations, shortness of breath, arm soreness and swelling, fatigue, nausea and I could not get out of bed. I called the hospital and left a message. The doctor called me back and advised me to go to the ER. By the time the doctor called me back, my chest pains and heart palpitations had resolved. The other symptoms still persisted- extreme fatigue and headache which lasted another 4 days. I started to feel better and it took about 6 days for all symptoms to resolve. I did not go to the ER since the cardiac symptoms have resolved. I am still having SOB.

Well I started getting swelling in my feet and legs and I went to urgent care and they gave me some Lasix pills and said it was fluid but it kept happening so I saw my PCD. My DR wanted me to see a vein DR, I did and then he diagnosed me with venous insufficiency. I do not recall the dates it was so long ago I'm sorry. The vein DR gave me a prescription for compression stockings and that has helped the swelling. There is still some swelling but it has helped, there is bearable pain as well.

Employee received 1st dose of Moderna vaccine on 12/23, remained for 15 min in observation post vaccination, no complications or reaction at the time, went home. 9 days later 1/1/2021 employee begat to have small rash to R hand/arm, they began to swell into hives. right Hand became swollen unable to close into a fist. Multiple test/labwork run no findings at this time. MD's unable to identify etiology, no new soap, hygiene products etc have been used. He was placed on steroid tx and was out of work for a wk, returned to work 1/7/2020. Symptoms have resolved at this time, MD is advising to get 2nd dose but will be under supervision.

Employee reported inflamed lymp node on the right axilla the following day he had the vaccine and did not disappear for more than a week. Will seek advise from his primary care provider for further evaluation

Friday 2-8-21 was the injection at 2:30 pm left arm was sore 15 minutes after injection, started noticing symptoms Saturday morning 1am massive headache took Motrin which helped. Flu like symptoms started around 9:30 am took Motrin again around noon on Saturday. Saturday night 8:30 pm started to get cold shivers until 1am woke up to massive headache took Motrin. Fell back to sleep about 2 am started to sweat and get hot. Woke up around 7:30 all was better except left armpit limp node was swollen to a tennis ball sized football shape lump which lasted for 5 days. Sunday 2-10-21 night started feeling an overwhelming since of anxiety of past, day 12 still working through the anxiety. Taking natural medications ( calming tea, Melatonin to help sleep) Have a prescription for Diazepam for flying have taken small doses to help sleep occasionally. Cut out evening coffee, drinking alcohol. Have been drinking more water.

01/18/2021-Patient became short of breath with c/o throat tightness and difficulty speaking 30min post vaccine. Given epi 0.3mg subcutaneous, Benadryl 50mg by mouth, placed on cardiac monitor for 4 hours with mild tachycardia post epi. Solu medrol 125mg given IV. Sent home and then returned 38 hours later with c/o epigastric pain, nausea, vomiting and weakness. Sent to Medical Center

Temperature 106, Malaise, Nausea, Vomiting, Joint redness, swelling and pain (hands), back pain, headache, visual disturbance (photosensitivity), Vertigo, Muscle Weakness, Shortness of breath all occuring over four day period. Continue to run a low grade temperature (99) intermittently.

Arm swelling , Soreness, pain. the following day(s) nausea, labored breathing, funny feeling like a heavy chest. dizziness ( still happens occasionally seven days after vaccination) fatigue still happening to date.

pt stated he received 2nd dose Moderna yesterday, today he has 4+ swollen to his face to the point he can't keep eye opened. stated took some Allegra and Benadryl. stated doesn't have any difficulty breathing. did c/o chill and low grade fever, didn't take temperate. alert and oriented x3. stated if will go see doctor or hospital if there is anything life threaten or problems get worse.

Two severe seizures 23 hours after injection, fever of 101.4. First seizures in more than a year. Oral thrush two days after injection, fever blisters on lips three days after injection.

Night of 2nd vaccine woke up with a high fever, and severe headache. Fever lasted 36 hours and peaked at 104.8 (with Tylenol). Fever was over 103 degrees for majority of 24 hour period. Fever went away after 36 hours. However, headaches have continued constantly (17 days and counting). Went to the Dr. on 2/19/21. They wanted an CT Scan of head and sinuses. Dr. Prescribed cefuroxime 250 MG tablet in case of sinus infection and ibuprofen 800 MG tablets. Insurance did not approve a STAT CT Scan, so Dr. told me to go to the ER if headache persisted. Went to the ER on 2/23/21. Dr's indicated Blood pressure was very high (180/120). I do not have a history of high blood pressure. They did a CT scan (normal) EKG (normal), and blood work. They inserted an IV with migraine cocktail to alleviate headache. Unfortunately no change. While in the ER they gave me: - Sodium Chloride - Tylenol - Metoclopramide (injection) - DiphenhydrAMINE (Benedryl) (injection) - Dexamethsone - Ketorolac (Toradol) They prescribed methylprednisolone (steroid). Went back to primary doctor on 2/25. Blood pressure remains high (average 158/112 throughout the day), headaches continue (constant). They did more blood work, urine sample, and another EKG. They also ordered a STRESS ECHOCARDIOGRAM. The prescribed lisinopril 10 MG tablet for blood pressure.

Approximately 45 minutes after injection mild onset of anaphylaxis response. Numb tongue, tingly lips, mild throat constriction but no issues swallowing or breathing. About 60 minutes post-injection, the patient self-administered two 25 mg tablets of Benadryl. Symptoms subsided 120 minutes later.

Chills - from 3am to 5:30am today My left arm is very tender / painful - on the spot where I got the shot. Also felt some swelling of nods under a my armpit. Tired/ body aching

Right sided mild facial swelling, left side facial droop-eye, corner of mouth, decreased forehead creases, loss of nasolabial fold and impaired speech.Treatment includes Acyclovir 400mg orally five times a day, Prednisone 10mg orally daily, Lacri-lube S.O.P. ophthalmic ointment to left eye at bedtime. Patient was to follow-up in 1 week. At follow-up patient continued to have left sided facial droop, feels like his left nostril is "closed", left ear feels full, swelling to left neck and shoulder. Provider plan to continue current medications and continue facial exercises. Follow-up set for 1 month.

Swelling if lymph node in left armpit. Armpit is swollen and tender. It is still currently swollen as of march 28th

24 hrs later i began to become tired then developed a low grade temp 101.5 orally then my right arm pit same side of the shot given my lymph node in the arm pit swelled to the size of a softball then the swelling went into the right side of my neck and down into the right side of my peck also noted pain in the back of neck near my spin going down to just below the scapula this lasted 4 days with the exception of the arm pit swelling I still have that but not painfull it is now the size of a tennis ball on my 5th day after 1 st shot temp lasted 2 days just took advil for the temp no other symptoms occured with this so far

I'm not sure if that is the correct lot number (it was hard to read). Low fever of 99.1 (I'm always below 98.6) with some chills. My hands and joints swelled up so much and hurt and my rib cage was extremely painful. These are common symptoms of RA when I am in a flare. I felt better on April 3rd.

Swollen lymph node right arm, Fatigue, Headache x 8 days. Muscle pain, Chills, Nausea, Vomiting, Dizziness, Weakness and Fever(101.8)x 2 days.

Difficulty in breathing; Swelling of face; Swelling of face and tongue; This spontaneous case was reported by a health care professional (subsequently medically confirmed) and describes the occurrence of DYSPNOEA (Difficulty in breathing), SWELLING FACE (Swelling of face) and SWOLLEN TONGUE (Swelling of face and tongue) in a 47-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 031A21A) for COVID-19 vaccination. Concurrent medical conditions included Penicillin allergy (Not sure about the allergy). On 15-Apr-2021 at 1:52 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 15-Apr-2021 at 2:22 PM, the patient experienced DYSPNOEA (Difficulty in breathing) (seriousness criteria medically significant and intervention required), SWELLING FACE (Swelling of face) (seriousness criteria medically significant and intervention required) and SWOLLEN TONGUE (Swelling of face and tongue) (seriousness criteria medically significant and intervention required). At the time of the report, DYSPNOEA (Difficulty in breathing), SWELLING FACE (Swelling of face) and SWOLLEN TONGUE (Swelling of face and tongue) outcome was unknown. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments. EpiPen and 50 mg of Benadryl were given intramuscularly as a treatment for the events. 9-1-1 was called for further evaluation. No information on concomitant medications. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

Severe ear ringing, headache, gross mouth, raw throat, diarrhea, nausea, exhaustion, blurred vision, dry skin/chapped lips, cold sore

Vasculitis. 4-5 days after injection red, blood filled, blister-like (burst capillaries and dead tissue) swollen areas started to appear on face, ears, mouth and hands followed by significant swelling, pain and stiffness in a number of joints including knees, elbows, hands, fingers and feet. Biopsy pathology came back as vasculitis. Severe symptoms last 2 weeks and lesser symptoms continue following prescribed course of anti-inflammatories. Doctor suggested symptoms may persist until vaccine dissipates in symptoms (approx. 30 days from injection date).

My foot left foot swelled up, I am taking water pills to reduce the swelling. Had an ultrasound for blood clots in my leg which came back negative.

Site: Pain at Injection Site-Mild, Systemic: Allergic: Rash Generalized-Medium, Systemic: Body Aches Generalized-Medium, Systemic: Fever-Severe, Systemic: testicle swelling/lymphnodes groing swelling-Severe, Systemic: Headache-Severe, Systemic: Lymph Node Swelling-Severe, Systemic: Weakness-Severe, Additional Details: fever for 2 weeks, blister, rash all over body. drained and body felt beat up, fever of 102.4 for 2 weeks

enlarged axillary lymph node on L side - vaccination given on L deltoid. soft, palpable tender to touch, no nodules palpated. Decreasing in size slowly

Pain, swelling, redness in left calf. Area warm to touch. Symptoms started within 24 hours. Symptoms continued for two week before seeking medical appointment.

Numbness on top of young and my lips. I had confusion, anxiety headache, lungs were feeling extremely hot, nauseous, increase heart rate and elevate blood pressure extreme confusion . I was rushed inside the Er. I received a Ct scan, ,lab work, and a EKG I received IV ,fluids,Ativan,, Diphenhydramine, famotidine and Prednisone.

On March 21st Patient received the first dose of Moderna. On April 2nd he was diagnosed with pericarditis. He continues to require treatment for the pericarditis. He received the second dose on April 11th without any new problems. The vaccines were given at the Vaccine Clinic.

I had Covid-19 in January of 2021. I had mild symptoms. One day after the first dose of my vaccine I had Arrhythmia. I went the ER, and I was admitted for an Angiogram. I was transferred to the Medical Center. I was in the ICU for 3 days. I was transferred to Telemetry for 3 more days. I was discharged and I returned 2 days later because I had Arrhythmia. I was having chest pain and my White Cells were very high. I was in Telemetry for 4 days. I went back to work until a Few days after the second dose when I was hospitalized again.

After 2nd COVID VACCINE on 6/15/2021, 6/28 Notices Lump on my neck and went to Doctor Dr sent me for X-RAY After 6/28, i had feeling tires/fatigued and notices the lump on neck started smelling and pain. 7/6 I went to see a Dr and she was referred me to 1) take blood draw 2) ultrasound on my neck. After both results were completed, she was referred me to ENT doctor. 7/15 I went to see (ENT doctor) and I was referred to do biopsy my thyroid nodule. 7/23 i had biopsy my thyroid nodule.

Left axillary lymph node swelling. I am treating the swelling with Motrin 400 mg daily, and Tylenol 1000 mg daily for pain.

Three solid days of headaches, body aches, low grade fever. Lymph node near injection site swelled to size of large grapefruit, and was red and warm to touch.

Patient stated, " I have soreness under the left arm and noticed a one inch bump under my left arm on my lymph node."

Mild redness, mild swelling, moderate itching with onset at Day 8 after vaccination. No treatment, no complications.

Headache and tired. 25th I was really tired and generalized malaise - on and off for four days. Had a swollen auxiliary lymph node; size of golf ball. Went to a Walk-in clinic on 12-31-2020. They said it should decrease and to watch it and use hot compresses and massage it. I took Tylenol for pain as needed. Took a few days I was extremely tired and run down that three days. And had on and off nausea. One bout of vomiting and diarrhea on and off. Resolved eventually on it's own.

the day of vaccine; Headache and achy body - day after through Sunday - generalized malaise; bouts of nausea and diarrhea and threw up once; Swollen auxiliary lymph node and went on the 30th to Urgent Care Clinic - no tests; told me to use warm compresses, massage area and I took tylenol for pain. And about three days after the 30th before all of that resolved. fatigue.

Chills, aches, fatigue, low fever (100.1-100.7), headache, swollen gland right armpit. After 72 hours, lesser side effects, but still headache, fatigue, swollen gland.

I had my second injection on Sunday morning 1/24/21 at 9:00 AM. I was fine through the day. The previous dose (dose #1) was on 12/29/20 and I became symptomatic the following day. I had aches, malaise and fevers of 102.7 on 12/30/20. The fevers lasted approximately 12 hours and resolved with Tylenol. My left deltoid was very swollen and quite painful. The swelling and pain resolved within 24 hours after the first injection. Prior to dose #2 and through the day on 1/24, I used Tylenol and Celebrex, both medications were ingested at 8:45 and the tylenol wa again ingested at 11pm prior to going yo bed. By 12:15, I had severe bilateral calf pain. Fever started shortly after that. Severe Headaches and Photophobia began at around 1 am. I had a vey difficult time walking and was quite dizzy through the night. Unable to sleep more than a couple of minutes at a time. By 6:45 am, my fever was around 103.5. I have used Tylenol and Ibuprofen since 1/25/21, 6:45 am. both medications have been utilized around the clock on TID basis. Fever dissipated by 1/25/21 evening. Only a mild headache is present. The injection site was swollen, indurated and painful to touch similar to cellulitis. I have not used antibiotics, drew a line and have monitored the redness, it is slowly resolving. By 17:30 on 1/26/21, I have a mild headache, mild malaise and chills. No fever. Arm is still swollen red and hot. I have not had respiratory or GI symptoms and have no history f Covid Exposure and have tested negative on multiple occasions.

Head aches, Arm became sore, at about 10:00pm, then noted that is was swollen, red painful to the touch. Area of redness was 70X120mm . Reported that his stomach felt " funny"

6 days of severe headaches, body aches, cold sweats, swollen lymph nodes; 2 days of on and off fevers (started on 3rd day), over 100 Fahrenheit; 2 days of ears swollen up, red, ringing, and pain.

Fever, Chills, Lymph Node swelling, Body ache, Joint Pain, Loss of Smell / Taste, Extreme Headache, Fatigue, Nausea. Pretty much felt like I was hit by a bus for 24+ hours. Pain at injection site for 48+ hours.

Soreness of right arm, stiffness of muscles on the right side of my neck, headache on the back side of my head temperature as hi as 103.2 swollen lymph nodes in right armpit

I had all listed most-common side effects (fever, body aches, chills, fever, fatigue). The main, additional side effect I want to report is lymph-node shooting pains under my right armpit and throughout my right arm and forearm that occurred on 2/11 and 2/12 (one and two days after). Three days after the shot, I noticed slight lymph node shooting pain on my right jaw, under ear. I?ll be getting the second shot...it beats COVID-19 by at least a mile!

Developed a large amount of swelling in the armpit of the arm the injection was made. Less than 24 hours later developed chills, sweat, aches and pain. By 30 hours after the injection I developed pain in my lower back that spread to my right ground. In 48 hours I was now experience excruciating pain in my groin with a constant and intolerable pain down my leg into the knee area which continued for hours. I was unable to find a position of comfort and was taken to the ER . I was immediately given a morphine drip which was not successful and then administered Dilaudid for the pain which was able to calm it down but not end it. At the time of this writing (About 72 hours after 2nd injection) I am unable to stand or walk without pain in my groin and knee area. Part of my thigh and Knee are have developed numbness and extreme discomfort. I can finally only sit with much pain. This Moderna Vaccine was administered through my employer.

Patient developed sob. Admitted on 2/16/21 with cardiogenic shock, acute renal failure and liver inflammation. Diagnosed with multisystem inflammatory disorder from COVID-19. Thought to be related to diagnosis on 1/25/21 but given recent receipt of vaccine reporting in case there are trends.

right axillary lymphadenopathy 24-36 hours post shot that is still present right flank pain morning after the shot with duration of 6 hours. on/off fever for 1st 24 hours

after second shot for a few days my upper left arm was like a warm orange fruit sized rash lump. Now the last few weeks I have arthritis in my hands and fingers, also lower back cramps, and the last few days my left knee is hurting for no reason. I take aleve and it doesn't help. I wrapped it today in ace bandage and am using a cane. I am very upset. I have done nothing and this is all since the last shot.

Rash and small white dots on both palms. Left palm is worse than left palm. Feel itchy and dull pain if touched. Swelling in both palms.

Swollen, painful, itchy welt starting 24 hrs after shot, lingering, persistent nausea 6+ days post-shot.

Pain in the right Throat and Neck area, slightly swollen. pain in the Throat when swallowing. No fever, is ongoing for 2 days now.

Patient received 1st dose of Moderna vaccine on 3/19/21 (Lot # 014M20A on LD). Six days later, he had visited his primary care provider complaining about his left arm pit swollen lymph node. Per note, patient said initial reaction was soreness to the left arm. On 3/25/21 morning, he started to feel a lymph node in the left axilla.

On the evening of 04/01/2021 I noticed a sudden itching sensation in my right arm and when I scratched it discovered the area to be swollen. Upon self examination I found the area be swollen in a disc shape approx 3 inches across and 1/2 to 3/4 inches deep. It is feverish to the touch. This is a sudden presentation. The area was not swollen or feverish earlier in the day. An online searh found tht 'Covid arm' seems to describe the symptoms and I intend to take Tylenol if necessary.

patient self reported tetracycline allergy that resulted in difficulty breathing and hives. Reaction happened many years ago. I asked patient to wait an additional 10 minutes for a total of 25 minutes so we could keep him under observation. After his 25 minutes patient reported that his fingers felt swollen and he had taken his wedding ring off to show me. Patient also reported that his lips felt "tingly". I observed the patient and noted no flushing, no sweating, no rapid pulse. I took the patients blood pressure and it was 121/80. I gave the patient Benadryl and asked him to wait for another 15 minutes so I could observe him. After the 15 minutes I observed the patient again and he still had no flushing or swelling and he reported that he no longer felt "tingly" and felt fine.

Patient had swelling under arms and around breast area. Became large, red ad painful. Came for 2nd dose and was referred to primary who stated he could still receive the 2nd dose.

Fever the following morning (which broke later in the day), along with a lot of pain throughout arm and shoulder (continuing after 3 days). A lot of swelling in armpit (continuing after 3 days). Fatigue.

"Moderna Arm." 8 days after injection, I got a raised, red welt about 4 inches in radius that was extremely itchy. Cleared up 4 days after.

He got the vaccine, started to get the headache within 45 minutes, ran some errands and after a couple of hours he felt like something was burning on his buttock, and noticed a really bad red rash on the left side on the left cheek from the crack outward. It was extremely hot to the touch and very sore, kind of throbbing and swollen and progressively got worse. He was just not feeling well, nauseous and dizzy and went to sleep but when he woke up it had spread to the other cheek. It looks like he got burned or scalded red/purple in color. He has no reaction on the arm itself, but only on the buttock and a blistery, blood red, leathery feeling rash/blotch on his entire buttock to both hips on both sides. It is difficult for him to sit. He also had headache, the muscle pain, joint pain, chills, nausea. He did not vomit but had not eaten anything. He has had a high fever up to 103 until this morning 4/8/21 which is about 99-100. He woke up soaking wet today. He has not been able to turn his neck, and not able to lift his arm above his waist level since the vaccine, and not able to turn his neck to the left at all. He can turn it 5-10 degrees, but right is okay. He took some Benadryl over the last 2 days for the reaction but it has not. He also has taken aspirin/Aleve for the fever. He was so sock and had no energy and could not sleep but could not keep his eyes open either, was not able to open them. He did write his doctor when the rash was only on one side, which they did not give him any advice as he was not feeling any worse at that time. He was at 101 fever throughout the day and then at night went to 102. He was hoping that the rash would be better, but actually worse as described above. He has not had any appetite, trying to drink fluids but made him nauseous, and he normally drinks water all day long. His normal temp is 97.7. He has been taking showers to try and keep his fevers down and the water hitting the rash feels like somebody is pouring scolding water on it. He did call Moderna on 4/6/21 asking if this was a reaction that anybody has reported, and he is waiting for somebody to call him back.

Patient reports around 5 days after receiving Moderna vaccine he experienced fever, diarrhea, n/v and SOB. Pt presented 4/07/21 to LGH ED with unremarkable blood work and negative chest x-ray, Covid negative- Pt discharged. 4/12/21 pt represented to LGH ED for some concerns and worsening sob with talking and walking and found to have PE and pneumonia

Left leg with edema, unable to bend Holman Sign (-) R =46 Left 46 R= 40 L=41 R=36 36 Difficulty in walking 4/16 #21= 4/16 Doctor or other health care professional office clinic visit

Patient reports 2nd covid moderna vaccine on 4/11/21, and the next day noticed swelling/itchiness in his right forehead which extended to right peri-orbital area.

PER PATIENT REPORT, PAIN A WEEK LATER MY LEG WAS ACHING. I USED ICY HOT, MASSAGER. STARTED SWELLING, WENT TO WALK IN. THEY DID AN ULTRASOUND AND SAID I HAD A BLOOD CLOT IN MY LEG AND IT WAS TRAVELING TO MY LUNGS. THERE WERE A COUPLE SPECKS ON LUNG PER XRAY.

I felt extremely dizzy about 2 hours after my 2nd vaccination of Moderna so I tried to take it easy and stayed in bed most of the day and night . The day after I did try to walk outside and suddenly became extremely dizzy while carrying an item and fell in my driveway without even having the ability to put my hands out front. My face is now swollen, cut and bruised and I also have pain in my neck.I have pictures of my face after my fall and had to call out of work today Monday 4/26/2021 as a result.

Patient received the 2nd Moderna vaccine on 4/19/2021. On 4/20/21, patient had typical side effects such as fever, fatigue, headache, and arm soreness. Patient took Tylenol to treat symptoms. On 4/21/21, patient said he started to develop swelling around base of neck on both sides and had difficulty breathing. He stated that he also had right arm numbness where the injection was given as well as blurry vision. According to patient, his blood pressure was 220/145 and his blood glucose was over 300. Patient went to primary care physician on 4/26/21 about his neck still being swollen after his vaccination. He said his physician gave him diphenhydramine and a steroid shot for the reaction. Patient came to the pharmacy to report his side effects on 4/26/2021.

Got vaccinated on 04/18/2021 on Sunday. After one week got rash/redness on the vaccinated arm, thickness and swelling a bit. Arm also feels ichy. Having also a cough since Sunday ( 04/25/2021)

After about a week after the shot I noticed raised, itchy, burning red patches on my right hand. I will say that I am not sure this is related to the shot but wanted to report it as it is different from any other skin reactions I've had. It's been three weeks now and it still itches and burns as much as it did three weeks ago. I have tried applying Triamcinolone Acetonide .1% steroid cream which does help. I have also tried antibiotic ointment covered by bandages overnight (no effect), Eucerin (no effect), and Aquaphor (no effect).

Swollen area around injection spot. Became red, puffy and irritated about 8 days after the injection. The spot is still a little red and irritated today. No treatment.

Pt reported at ~2000 hours on 4/27/2021, he experienced chills, body pain, and a lot of pain in his left arm. And late into the night his body pain worsen and had the shivers. On 4/28/2021, pt reported the pain in his left arm radiates up into the left side of his jaw area and there is a ball size lump underneath his left ear area with pain when he turn his head. Pt reported he took Tylenol on 4/27/2021 at 2300 hours up until 4/28/2021 1400 hours, helped with the chills and body pain. Advised pt that ADEs usually occur within first 3 days post-vaccination and resolve within 1-2 days of onset. Lymphadenopathy is not as common and usually resolves within 10 days. Advised pt can take either Iburprofen or Aleve with food to help with the pain. Recommend pt to contact MD if pain worsen or swelling has not gone down by next week. PharmD

Fever (as high as 103.5) for 48 hours, severe leg pain in both legs (especially in both knees) , chills, swollen and dry eyes, restless legs, arm pain (same arm as shot), big red rash on same arm as shot (still there 4 days later) , mouth blisters, fever blisters on lips, fatigue, lethargic (still occurring), day dreaming (still occurring), severe headaches, blurry vision, change in taste (still occurring)

After 7 days I noticed a red mark / rash around the area the shot was given. It itches on and off. The area also feels swollen, like a lump. Was just reading about COVID-Arm, and it sounds like the same thing. While it's only been 7 days since my first shot, I'm going to continue to monitor, apply ice, and use Benadryl as needed, and if it doesn't go away in another week, will schedule a doctors appointment to be safe.

Patient came in two days after getting vaccine with a complaint of left leg swelling. Patient sent for US Lower ext Venous Duplex Left Results where Deep Venous Thrombosis

Swollen lymph nodes in neck and shoulder. Harmless. Time course: one has almost disappeared after five weeks, the other is smaller but may need a couple more weeks.

Day after Injection: Fever 100.5, chills, head ache, injection site sore Day 2 to da 4: no symptoms day 5: Diminished sensation in skin of upper arm day 6 to 11: Complete numbness in armpit, lower halve of upper arm, "tingling numbness" extends to left side of chest and left side of chin. Armpit area feels like after a Novocain shot at the dentist. Feeling a "lump" under armpit which is not actually present. Day 11: Fever of 100 and headache Day 12 to14 : Sensation changes from numbness to partial numbness, itching, tingling, light pain. I take that as an improvement. The "lump feeling is still present but diminished. Left chest itchy but not numb. Chin sensations back to normal. Lower upper arm slightly itchy/hyper sensitive (feels "raw") Day 13: low grade fever pm. We have arrived in the present...

Pt. received 2nd Covid vaccine on 05/14/2021. On 05/15/2021 pt. reports not feeling well with s/s of body aches and chills. Pt. reports that on 5/16/21 that he noticed fever, cough and increased SOB. Pt. presents with c/o increase SOB on 05/18/2021. Pt. was admitted with diagnosis of right upper and middle lobe pneumonia on 05/18/2021. Pt. required 2-3 L of O2 per nasal cannula. Pt. was also on antibiotics on Rocephin 1 gm IV every 24 hours. Pt. received a one time dose of Azithromycin 500 mg in ED.

Patient is 48yo, presented 48h after 2nd Moderna vacccine with an acute right MCA stroke, required IV tpa and thrombectomy. Only known risk factor is active cigarette smoking.

Headache, fever, chills, shortness of breath, generalized weakness, decreased appetite. Was seen in ER and labs were done. Troponin was elevated 0.525, CRP 10.2, D-dimer 1.01, WBC 10.02. CT of head was negative and CT angio of chest showed no PE or pneumonia. Has a headache and was given pain medication. Was transferred to Healthcare for admission.

Diagnosed with Gillain Barré syndrome and I would to be involved with a case study to determine if the vaccine caused the development of my condition and would like to know if similar reports have been made to help the community. Still undergoing treatment IVIG.

After receiving the 2nd Moderna Covid Vacine I noticed shortness of breath, chronic dry coughing and fatigue/tirdness. Each week was progressively getting worse and rapid declining in my ability to fuction. I was gaining weigh and felt very tired, but thought it was respitory infection and tried to rest hoping it would clear up and improve. After several weeks, I noticed that both feet and legs started to swell and wouldnt return to normal. The decline was rapidly getting worse and I was not able to simply tasks. I tried to get an appointment at my primary physisan and was unable to get an appt, they recommeded I visit urgent care, so I went and was told to go to ER, where I was admitted to the hospital for congestive heart failure.

Moderna COVID-19 Vaccine EUA - Dizzy, cold sweating, rapid heart beat, soreness. One week later swelling at injection site with red oval (6 inches by 4 inches) with redish and white color and bumps. Under arm of same arm injection site swelling in arm pit area.

Patient got his Covid vaccine this past Thursday, 2 days ago. He experienced typical side effects of a sore left shoulder and some fatigue but was feeling well until this afternoon around 1:55 PM when he noticed throbbing of his left hand. He looked down and noticed that there was a purple discoloration to his middle finger and distal palmar aspect of his hand. He felt like there was maybe some swelling as well and that he might have been having an allergic reaction so called the emergency department for further advice and came in for evaluation. By the time I arrived to the emergency department the patient's left hand was no longer swollen and there was only a small purple discoloration to the palmar proximal middle finger. I was concerned that the patient developed a small blood clot that was resolved upon evaluation.

About 24 hours after receiving vaccine, noticed very slight pain and small blistering in right cheek area on face. Did not think too much of it at first, however the area grew a little and swelled up. Consulted with my doctor and they diagnosed Shingles. Am currently prescribed Valtrex for shingles.

Individual stated, "felt small bump on my left underarm, which is the same arm I received vaccination".

The next morning following the injection I was starting to feel flu-like symptoms, along with muscle aches that continued throughout the day and became worse/ I also felt very warm as if I had a fever even though my temp. never went above 99.0; the worst symptom was a rash/inflammation on my upper back that extended to my neck and ears, and I even had swelling in the neck area, this inflammation was so intense throughout the day that it made me feel like I had a much higher temp., when this finally subsided, I developed chills/shakes that lasted only for a short time

Painless Left supraclavicular lymph note about 1.5-2 cm, painless. No other symptoms, due to my age and no other lymph nodes and that it persisted saw my MD and work up for possibly cancer.

1. Left arm became red, itchy and swelling. 2. Blood pressure become lower than average 3. Pain at the muscle of left under arm .

Pt reports within 1 hr of receiving vaccine, he started with L sided lip/tongue swelling, L neck and "side swelling", chills, HA, body aches. Denies SOB, respiratory distress, difficulty swallowing, chest pain, confusion, changes in speech, numbness/tingling. Per pt this occurred 2/12/2021, angioedema, neck, side swelling resolved 2/13/2021. Persisted with HA, body aches, chills. Reported events to PCP office 2/17/2021, at time of call pt asymptomatic, symptoms fully resolved. Pt seeking advice from PCP prior to next dose which is scheduled 03/12/2021

SWOLLEN SUPRACLAVICULAR LYMPH NODE ON THE LEFT SIDE NECK AND MUSCULAR PAIN IN LEGS TWO IBUPROFEN EVERY NIGHT AT BED TIME FOR 5 NIGHTS. TODAY IS DAY 29 - LYMPH NODE IS STILL SWOLLEN BUT SIGNIFICANTLY SMALLER IN SIZE

Fatigue, tingling in lips and face Narrative: Employee reported localized swelling, chills with diaphoresis, extreme fatigue & tingling in lips face lasting several hours. Pt recovered spontaneously without further intervention.

2-16-21; headache, eyes sensitive sunlight, sore left shoulder. 2-17-21; sore left shoulder, eyes sensitive to sunlight, headache, triceps on left arm sensitive to the touch with some swelling. 2-18-21: armpit swollen with a huge round circle underneath armpit area. no rash, no redness, no fluid leakage. Called and spoke with on-call nurse, who told me to use cold packs. Made an appointment with my doctor over the telephone. administered probiotics/antibiotics for 7 days. NOTE: Shot was given in my left shoulder, all problems are on the left side. I also had corvid in September 2020 and it took me at least 3 months to recover or feel normal again.

Swelling of sites of prior dermatologic filler work in face, resolved on its own within 4 hours of onset.

Swelling, itching and redness and soreness on left arm at injection site as well as a swollen lymph node near left clavicle.

Three days after receiving the vaccine I developed a massive cold sore on my upper lip. I have never had a cold sore in my life prior.

Swelling and pain in arm with headache and nausea. It has been a month since the shot and I still have a knot in arm and I am very sore. Swelling comes and goes still. Can?t hardly raise my arm after a month of getting shot

8pm teeth chattering chills By Sunday morning 9am 100.9 fever and swollen underarm lymph nodes Sunday 3pm no fever (with ibuprofen) Exhaustion (lasted 3 days) Inability to regulate body temperature (no fever) 2 additional days (hot/cold and sweats) Swollen lymph nodes lasted 5 days

First shot I was totally ok, apart from a lump I got on my neck, did an ultrasound and they didn?t find anything bed, I was told it was because of the moderna shot. Second shot I got an excruciating pain on my left arm where they gave me the shot, on the next day I got a high fever 103.8, I could barely walk to the bathroom, headache, and just feeling really sick and weak, and the lump on my neck got bigger and it seems like I have more than one now

After the first dose of Moderna, 6 hours after taking the COVID19 vaccine the following side effects started: sore arm(swelling feeling at the shot arm), fever, aches throughout body, tired, and chill. It lasted for 2 days and suddenly on the 3rd day, a pain under armpit with a lump (the same left arm where the vaccine shot). That lasted for 2-3 days.

Pt developed symptoms of anaphylaxis: nausea, anxiety, chest tightness, throat tightness about 13 minutes after injection. Was given 0.3 mg epinephrine and sent by ambulance to ER.

4pm. Headaches, chills, low fever, joint pains, muscle pains, weakness, dizziness, diarrhea, swollen glands, thirst

Rash on the left arm that has increased in size since the vaccination. Swollen underarm on the left side that happened a few days after the vaccination.

Body muscle aches, Headache, extreme fatigue, trouble sleeping even though I am exhausted. swollen armpit in left side

Moderate to severe rash, spreading steadily for the past two days. Currently presenting on both elbows, both palms and backs of hands, abdomen (both sides), and tops of thighs/groin. Rash includes raised red bumps, swelling, hives, and itching. Bumps are from 1mm to 1cm, swollen, red, and itching. Widespread across much of body, and progressive (expanding).

Moderna COVID-19 Vaccine EUA. Starting the next morning, Fever, body ache, headache, back/joint pain, something in my left armpit swole up between a golf ball to tennis ball size, throat sore, swelling in tongue and gums (kind of blistery like I burnt it on hot pizza is the best way I can describe it). most of the symptoms lasted for a day and a half or so. Four days later, still feverish at times, mouth is still tender (most of the swelling went down but not all) swelling in armpit has went down but not gone.

Arm swelling has increased today, as has the pain. I have a large lump at the injection site which is itchy. It is reddened but there doesn't appear to be a rash.

Patient was immunized on 3/16/21 shortly after being discharged from the hospital. He was readmitted with abdominal pain and complaints of bilateral hand tingling. Neurology was consulted and working diagnosis was Guillain-Barre Syndrome (GBS). Patient was given a 5 dose series of IVIG 0.4g/kg.

9 days following IM injection pt noticed swelling of his supraclavicular lymph node on the same side as the injection.

ADVERSE EVENT BEGIN WITH PAIN AND STIFFNESS IN NECK, THEN PAIN AND STIFFNESS PLUS ERYTHEMA AND EDEMA IN ARMS, FOREARMS, THORAX ANT AND POST, THIGHS, LEGS, ANKLES AND FEET. THIS WAS FOLLOWED BY THE DEVELOPMENT OF BULLOUS LESIONS ON PINNAE, ARMS, HANDS, LEGS AND FEET. HIS FACE WAS SPARED. HE HAD NO FEVER. HE DEVELOPED MARKED EDEMA IN ALL AREAS, SO SEVERE SHOES COULD NOT BE DONNED. HE SOUGHT TREATMENT FROM PCP AND DERMATOLOGIST, HAD 4 (FOUR) SKIN BIOPSIES, LAST FROM RIGHT LATERAL KNEE SKIN WAS POSITIVE FOR BULLOUS PEMPHIGOID. HE WAS TREATED WITH TRIAMCINOLONE TOPICALLY, PREDNISONE ORALLY, CLOBETASOL TOPICALLY, DOXYCYCLINE PO, NIACINAMIDE PO. AS HE IMPROVED HE DESQUAMATED DIFFUSELY AND BULLOUS LESIONS ARE HEALING. HE HAD NO EYE, MUCOSAL, GI OR GENITAL INVOLVEMENT. HE WAS ABLE TO RETURN TO WORK SEVEN WEEKS AFTER THIS ILLNESS BEGAN.

I had flu like symptoms the next day, fever, chills, body aches, headache etc... and then on 4/9 I woke up with a red swollen and itchy rash ALL over my body. Other than all this I feel ok.

Raised, bumpy, red, swollen rash on both lower forearms and backs of arms and elbows, lower back to buttocks, calves of both legs, back of neck and back of hands. Occurred day following vaccine and has persisted for over a week so far.

very much like a blood clot; R leg swelling; very hematoma; big red patch; warm sensation in the the leg; pain that he never had; normal pain in the injection site; This spontaneous case was reported by a consumer and describes the occurrence of THROMBOSIS (very much like a blood clot) in a 49-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. The patient's past medical history included No adverse event (No reported medical history). On 01-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 01-Apr-2021, the patient experienced VACCINATION SITE PAIN (normal pain in the injection site). On 04-Apr-2021, the patient experienced THROMBOSIS (very much like a blood clot) (seriousness criterion medically significant), PERIPHERAL SWELLING (R leg swelling), HAEMATOMA (very hematoma), ERYTHEMA (big red patch), FEELING HOT (warm sensation in the the leg) and PAIN IN EXTREMITY (pain that he never had). At the time of the report, THROMBOSIS (very much like a blood clot), PERIPHERAL SWELLING (R leg swelling), HAEMATOMA (very hematoma), ERYTHEMA (big red patch), FEELING HOT (warm sensation in the the leg), PAIN IN EXTREMITY (pain that he never had) and VACCINATION SITE PAIN (normal pain in the injection site) outcome was unknown. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown Route) was unknown.; Sender's Comments: Very limited information regarding these events has been provided at this time. The events are probably related to the patient's comorbidities

12-18 hours after vaccine had feeling of hot/cold/shivering/myalgia. Few days later started to have chest pain, shortness of breath that progressed and eventually was severe. seen at ER 2/22/21 and found to have large pericardial effusion on bedside u/s and acute ST changes on EKG. transferred to second hospital and admitted 2/22/21-2/25/21. He was treated with pericardial windows to remove fluid and discharged on ibuprofen and colchicine for presumed viral pericarditis.

Dizziness, blurred vision, fatigue, headaches, chills, low grade fever, muscle pain, joint pain, high blood pressure, and swelling of the throat.

redness, swell and itchiness around neck and top left corner of chest. started appearing on the day i got the second dose of the vaccine. It increased following day and the day after.

Swollen Middle Finger, with throbbing pain. I feel as though the vaccine triggered this issue. My middle finger was not swollen before the 1st vaccine dose.

On 4/27/21 at around 4:15 patient came to store to report a side effect after been immunized against Covid 19 with a Moderna vaccine on 4/25/21. The patient had a chief complaint of pain and swollen armpit . After looking into the area, I observed that the swelling looks as if he had the size of a small ball on his armpit. I Suggested to take Aleve and observe for fever and that if it gets worst see MD immediately. Patient was grateful for consultation and will keep in touch if there?s not improvement.

Patient hospitalized from 4/18/21-4/23/21 4/18 Hospital Day 1: Patient (pt) presented to the ER via EMS for aphasia/altered mental status that began that AM. Pt had received his 2nd COVID19 vaccine (Moderna) x3 days prior. Pt had generalized body aches/fever and was taking acetaminophen for his symptoms with mild relief per wife. Per ER notes, patient had clear speech but was not making sense and easily agitated. 4/19-4/21 Hospital Day 2-4: Patient with altered mental status. Was non-verbal and easily agitated. There was concern for encephalitis, infectious vs autoimmune. On 4/19, antibiotics were discontinued and patient was being treated with steroids for possible autoimmune encephalitis. 4/22 Hospital Day 5: Patient was doing better and more talkative. Patient was able to have a limited conversation, appeared alert and oriented with some slow speech. Per medical chart, family reported patient was at "50% back to baseline." 4/23 Hospital Day 6: Patient was back at baseline and completed 3 days of IV steroids. Patient reported not being able to recall anything from "Saturday 4/17 to Wednesday 4/21". Patient was discharged on 4/23 and recommended to follow up with neurology and was not discharged with any steroids. Treatments: Fever: APAP 1 IVPB x1 (4/18-4/19), APAP 650 mg PO x1 (4/20-4/21) Encephalitis: Methylprednisolone 125 mg IVPB x1 (4/18); Methylprednisolone 500 mg IVPB BID (4/19-4/23) ID: Acyclovir 700 mg IVPB q8h (HSV infection) [4/18-4/19]; Cefepime 2 g IVPB x1 (Sepsis) [4/18]; Ceftriaxone 2 g IVPB q12h (CNS infection) [4/18-4/19]; Vancomycin 2.25 g IVPB x1, 1.5 g IVPB q12h (CNS infection) [4/18-4/19]

Shot was on my left arm. My left side of the face felt like i came home from a brutal dentist appointment. The whole side of my face felt numb. My lymph node was also giving me pain..... It is now eight days after my shot, and I still feel a little numbness on the left side of my face. It is not as prevalent as it was, i am not taking any Tylenol or Advil because of it, although i did on day 1-3. (Tylenol)

Patient presented 5/5/21 with pain in Right deltoid area. Area slightly swollen. Suggested he ice area and take anti-inflammatory medication

Patient states he developed fatigue myalgias 8 hours after vaccine, then about two hours later, he became short of breath. He subsequently reported intermittent shortness of breath and leg swelling. May 5 noted to have atrial fibrillation/ flutter with rapid rate. Unclear if patient had atrial fibrillation at time of initial symptoms and unclear if related to the vaccine at all.

body and joint aches all over body. pain/swelling/hardness in left shoulder (continues into next day--injection site). cold hands and feet, chills, low-grade fever of 100.4., headache, sinus pressure, diarrhea. thirsty.

Noticed severe pain in right hand and wrist two days after receiving vaccine. I then began to have severe pain in both shoulders, both knees, both hips, and both elbows. The pain started on 4/10/2021, and became very severe over the course of that week. The pain started to lessen starting the week of 4/2/2021 and has seemed to improve but the right shoulder still has shooting pains when moved certain ways. My right hand is still swollen and I cannot make a full fist. I am unable to fully bend my knees. My left elbow still has shooting pains when moved into certain positions

I was vaccinated on 01/20/21. On 02/11/21 I started having stiffness in my neck. On 02/15/21 it got worse and could not turn my head as the neck was stiff and swollen. My neck got better after few days and the pain moved to both my biceps. They were also swollen and painful. After few days the pain was gone but I started having pain on both my thighs. They were also swollen and very painful. After few days the pain disappeared and it moved to both legs and feet. At that same time my skin was also getting inflamed and peeling off. I could not even take a shower or bath as the skin was very sensitive and painful. I also started developing some blisters on most parts of my body. It was diagnosed a Bullous Pemphigoid.

Suffered the following side effects starting at 2am on Sunday and ending around midnight on Sunday. Fever Sweating Tingling tongue Sore body to the touch - Almost like the nerve ending in my skin were hypersensitive Headache Swollen shoulder Diarrhea

Fever, nausea, headache, abdominal pain, sepsis upon admission with negative blood cultures, UA, fever to 104 F; diagnosed with proximal descending thoracic aorta thrombus

12/18/2020: ER visit showing Patient Chief complaint of Left lower leg pain; plt count 243x10^3 WNL; Given Clindamycin 600mg IV in the ER and discharged on Bactrim 800mg PO for Acute Cellulitis diagnosis. 1/2021: Follow-up at PCP office showed plt wnl on routine labs. Resolution of leg symptoms per patient. 3/15/21 & 4/15/21: Received Moderna vaccine one & two at Public health clinic (Additional Information for Item 12: Cigarette smoker 10.5 Pack years, hypertension) Additional information for Item 18: 4/19/2021-4/27/21: Presented to Medical Center ER with complaints of Left leg redness and weakness. Stated he felt weak and tired after receiving the second dose and has been feeling worse since. His friend brought him to the ER stating "he didn't seem like himself." Admitted for acute cellulitis of Left lower extremity, altered mental status, and started on IV Vancomycin (4/19/21-4/22/21) and Levaquin (4/19/21-4/26/21). Baseline plt 74 at admission. Rivaroxaban 10mg PO QD was given 4/19/21 until 4/21/21. Plt count continued to downtrend during admission. Hematology/Oncology service consulted on 4/22/21 who initially suggested thrombocytopenia possibly due to infection or DIC. Yet, worsening thrombocytopenia despite improvement of infection and clinical status was noted. The etiology was then suggested to be Vancomycin induced thrombocytopenia, so Vancomycin was stopped on 4/22/21. Platelet count Patient was discharged with p.o. prednisone and p.o. Levaquin on 4/27/21. Patient stated almost full resolution of LLE pain and redness. Plt count upon discharge was 51. Instructed to stop Rivaroxaban. 5/1/21:Patient presented to ER at Medical Center for Leg pain. US Doppler was negative and patient given Clindamycin IV 600mg in the ER and discharged with Bactrim 800mg qd to be continued until his PCP appointment. May 5, 2021: PCP placed patient on Clindamycin for recurrent cellulitis. 5/14/21-5/22/21: Patient presented to Medical Center ER with worsening left leg cellulitis. Patient was afebrile with a normal wbc count. Upon admission, Plt count was 36. Patient was started on Linezolid 600mg q12h and Ceftriaxone qd. Antibiotics were changed later to Tefalo 600mg Q12Hto be started on 5/15/21. ID consult recommended Daptomycin given patient's thrombocytopenia. Patient was continued on Daptomycin throughout admission and upon discharge, patient's leg was almost back to baseline. Plt count was 138. To rule out other causes of thrombocytopenia, patient medications were reviewed and imaging was done in addition to labs drawn during this admission. See above for the labs. All alternative causes during this admission were ruled out.

pain in his hands disappeared but now moved to the thighs,His thighs were painful,thighs were inflamed, pain moved to knee and legs, pain in feet; arms and biceps were swollen, thighs were swollen,His feet were swollen; his skin (entire body) started to peel off,The skin on his whole body was gone; his skin was very itchy; developed blisters all over the body; did not get a second shot; his whole body started to be inflamed, thighs were inflamed; could not shower for a few days; Rash,also given Prednisone for 2 weeks for the rash; skin test diagnosed him with Bullous pemphigoid; his neck got worse,he could not turn his head; his neck was swollen.; did not sleep well.; experienced stiffness in his neck; This spontaneous case was reported by an other health care professional and describes the occurrence of PEMPHIGOID (skin test diagnosed him with Bullous pemphigoid) in a 49-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 028L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. No Medical History information was reported. On 20-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 01-Feb-2021, the patient experienced MUSCULOSKELETAL STIFFNESS (experienced stiffness in his neck). On 11-Feb-2021, the patient experienced INSOMNIA (did not sleep well.). On 15-Feb-2021, the patient experienced MUSCULOSKELETAL DISCOMFORT (his neck got worse,he could not turn his head) and SWELLING (his neck was swollen.). On 16-Feb-2021, the patient experienced PEMPHIGOID (skin test diagnosed him with Bullous pemphigoid) (seriousness criterion medically significant), PAIN (pain in his hands disappeared but now moved to the thighs,His thighs were painful,thighs were inflamed, pain moved to knee and legs, pain in feet), PERIPHERAL SWELLING (arms and biceps were swollen, thighs were swollen,His feet were swollen), SKIN EXFOLIATION (his skin (entire body) started to peel off,The skin on his whole body was gone), PRURITUS (his skin was very itchy), BLISTER (developed blisters all over the body), INTENTIONAL PRODUCT USE ISSUE (did not get a second shot), INFLAMMATION (his whole body started to be inflamed, thighs were inflamed), IMPAIRED SELF-CARE (could not shower for a few days) and RASH (Rash,also given Prednisone for 2 weeks for the rash). The patient was treated with PREDNISONE for Adverse event, at a dose of 1 dosage form; ACETAMINOPHEN for Adverse event, at a dose of 1 dosage form; IBUPROFEN for Adverse event, at a dose of 1 dosage form; DOXYCYCLINE for Adverse event, at a dose of 1 dosage form; MESALAMINE for Adverse event, at a dose of 1 dosage form; CLOBETASOL PROPIONATE (CLOBETASOL [CLOBETASOL PROPIONATE]) (topical) for Adverse event, at a dose of 1 dosage form and HYDROXYZINE for Itching, at a dose of 1 dosage form. At the time of the report, PEMPHIGOID (skin test diagnosed him with Bullous pemphigoid), MUSCULOSKELETAL STIFFNESS (experienced stiffness in his neck), INSOMNIA (did not sleep well.), MUSCULOSKELETAL DISCOMFORT (his neck got worse,he could not turn his head), SWELLING (his neck was swollen.), PAIN (pain in his hands disappeared but now moved to the thighs,His thighs were painful,thighs were inflamed, pain moved to knee and legs, pain in feet), PERIPHERAL SWELLING (arms and biceps were swollen, thighs were swollen,His feet were swollen), SKIN EXFOLIATION (his skin (entire body) started to peel off,The skin on his whole body was gone), PRURITUS (his skin was very itchy), BLISTER (developed blisters all over the body), INTENTIONAL PRODUCT USE ISSUE (did not get a second shot), INFLAMMATION (his whole body started to be inflamed, thighs were inflamed), IMPAIRED SELF-CARE (could not shower for a few days) and RASH (Rash,also given Prednisone for 2 weeks for the rash) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Skin test: abnormal (abnormal) Skin test diagnosed him with bullous pemphigoid.. mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was withdrawn on an unknown date. For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments. No concomitant medications were reported. It was noted that the patient was being treated by a dermatologist. A "skin test" was completed and results indicate a diagnosis of bullous pemphigoid. It was advised that the patient not receive the second dose of the vaccine. Company Comment : Very limited information regarding these events has been provided at this time. Additional information required.; Sender's Comments: Very limited information regarding these events has been provided at this time. Additional information required.

Patient reported symptoms of chills brain fog and armpit swelling for full 24 hours started about 4 hours after vaccine administration.

Pt. states 04/28/2021 horrible headache, vision problems, muscle/joint pain, pain induced vomiting, rash throughout body. Still currently has signs of rash. Brain swelling, 05/02/2021 ER visit. 05/04/2021 Primary visit Ct scans, MRI, blood-work ran. Elevated white-blood count, nuero symptoms similar to ALS. Swelling around abdominal mid-section/ribs area, neuropathy in the legs and feet. Prescribed steroids for swelling 3x. Tramadol prescribed.

Severe swollwn face and lips, slurred speech and red hives all across the body. Mild breathing difficulty. Had to call 911 and was taken to the hospital

Cold sores on nose and mouth Tingling nerve sensation on face, scalp, and neck Minor first outbreak of shingles (painful bumps under right armpit) Tinnitus (from a 1 out of 10, to a 2 out of 10)

Myalgia, Arthralgia, Swelling/heat/redness/injection pain/ fatigue/lightheadedness/increased urination Narrative: Used OTC naproxen

WITHIN 24 HOURS OF SHOT: FATIGUE, MUSCLE ACHES, INJECTION SITE SORE, HEADACHE (LIKE SINUS PRESSURE) 24 HOURS AFTER SHOT: SWOLLEN LYMPH NODE, CHILLS, FEVER (100.4) 36 HOURS AFTER SHOT: LIKE NOTHING EVER HAPPENED

Chief Complaint Patient presents with ? Generalized Body Aches     Pt presents via EMS c/o DOE, dry non-productive cough, subjective fevers Tmax 101.9, decreased appetite, aches since testing + for COVID on 1/5.   Patient is a 50 year old male with PMH of Crohns/MS on fingolimod presenting to the Hospital for fevers, shortness of breath and weakness. Patient received COVID vaccine on 12/29. Patient had initial left arm discomfort though has had worsening weakness, cough, shortness of breath and fevers since that time. Patient tested positive for COVID19 on Patient has shortness of breath with exertion that is relieved by rest. Patient denies N/V/D. Patient has taken tylenol at home to attempt to alleviate symptoms.

MODERNA COVID-19 Vaccine. Lymph node swelling around 6pm day of vaccination, Jan 16th. Fever, headache, injection site pain, fatigue upon waking up around 10am on Jan 17th. Symptoms continued majority of the 17th and subsided by the morning of Jan 18th.

i had the usual aches after second dose after 24 hours i felt better but have a swollen lymph node under my arm out of the shoulder where got vaccine. is this a normal reaction?

Employee seen in clinic on 1/21/21 for severe headache (9 on 0-10 scale), severe neck pain (9 on 0-10 scale), lymph node involvement on left arm and left side of neck, bilateral leg cramps, nausea, vomiting, sensitivity to light, low grade fever (99.5), chills, upper and lower back pain (7 on 0-10 scale). Injection site; rash covering 3 x 4.5 inches on upper left arm above deltoid and below acromium process with 1/2 x 1/2 inch bulla. Gave ice pack for left arm, gauze for Bulla. Sent employee home with instructions to take NSAIDS after arriving home and before sleep. BP 143/96, Pulse 96, temp 99.5

First dose: headache, malaise Second dose: left arm sore, tender. Left arm swelled up to the size of a goose egg and I was unable to lift my left arm from my left side. Low grade fever, body aches, eyes looked sunken in, felt exhausted. I felt like I had the flu. I missed three days of work after the second dose. I took ibuprofen and iced the left arm and rested. I never had a reaction to the influenza vaccination in forty years. The first dose, I did not miss work. And the side effects went away the next day.

Felt his throat tingling, then noted (and confirmed by his wife) that his nose was swelling. Never had tongue, pharynx or lip swelling, only the nose.

1day after shot:Fever,chills, body ache. 2 days after shot: Symptoms from day before gone but noticed a Tennis ball sized lump under left arm/pit area. One week and one day after shot: slight swelling under left arm/pit area.

On day 5 armpits felt tender & sensitive, day 6 itching at injection site, day 7 rash at injection site and other parts of the body mainly upper torso area. Rash to the left and right of navel, armpit area, left & right side of chest were little more prevalent but some small red bumps on arms, should & back area as well

It began with severe chills and a low grade fever. The following morning, my fever increased and the highest level noted was 101.8. I had a loss of appetite, nausea, and no energy. My fever lasted for approximately 30 hours before subsiding. I alternated Tylenol and Alieve during my time with fever. On Sunday, February 7, I began having mouth sores and fever blister on my lips. For this, I used Lysine, both tablet and lip ointment.

Had vaccine and had a red spot and sore arm which went away after a couple days. Four days after the vaccine a blood vessel in my hand burst (I don't recall hitting it on anything at all). It puffed up about a centimeter and slowly went away over a few days. Then a little more than a week later the red spot came back and itched very badly and was sore again. It also faded after several days. then yesterday morning I woke up and my arm was sore at the injection site again only I started having the worst headache of my life that lasted 30 hours. I started shaking, sweating massively, I felt hot and cold at the same time, felt as if I had a very high fever but my temperature was 98.4 (totally normal). I was vomiting if I tried to eat or drink. I had severe body aches and EXTREME weakness throughout my body. My heart began to race at 150-160 bpm for several hours and I couldn't sleep. It has gotten about 50% better in the past few hours and will hopefully continue that way. I've never felt anything like it in my life. I need to know if it is safe for me to get the second shot.

Swelling of face/mouth. Rash and itchy all over body. lips are not as swollen as they were this am at 6:00am and Rash is still visible but not itchy, time I'm writing this is 12:33pm

On January 21, 2021 I started feeling pains in my right shoulder (1st shot was left shoulder) and the following day it had spread across my body, shoulders, chest, arms, legs and calves. I also had a severe headache along with the muscle pains and woke up each day since in a pool of sweat with the sheet soaked to this day. Due to the severe muscle pains, I started taking Tylenol and all the symptoms pointed to the virus itself. I was tested for the virus on Monday, January 25th with negative results on the morning of the 26th. I continued to self-medicate with Advil every four hours to remove the severe muscle pains noted above. To back track slightly, I had a colonoscopy on January 19, 2021 and one large polyp was removed without issue. Due to the full body muscles pains and taking the Advil, it likely caused bleeding from the polyp site of the colonoscopy and went to the ER and they transferred me back the hospital on January 28, 2021, the location of the colonoscopy, and hospital found nothing wrong with the colonoscopy during my 2.5 day stay there. The did an x-ray of my chest to test for the flu and related items and found everything to be clear. They also a CT of my abdomen to look for any abnormalities and found none. Through all this the muscle pains continued when I would move, the muscles would fire up and intense pain persisted until I could calm them down after about 30 mins of intense pain. Hospital also tested me twice for the COVID virus and each turned out negative. Overall, I?ve been tested for the virus nearly 12 times and all were negative. From the visit to Hospital, with the colonoscopy and no additional bleeding occurring, Hospital gave me a steroid called Prednisone to mask the pain on Saturday, January 30, 2021 at about 1pm and by 4pm they fully released me with no idea what was causing the severe muscle pain across my body when I moved. I literally just walked out of the hospital since the steroid masked the muscle pain issue. The steroids worked but I was still walking up in a pool of sweat and very clammy and wet each morning from 1am until I woke up. On February 2, 2021 I had 3 bowel movements that were all dark purple and full of blood clots which led me back to Hospital and the ER could not get in touch with the Hospital Doctors for transfer so they admitted me to the Hospital, thank God. On February 4, 2021 Methodist performed an emergency colonoscopy to clamp the polyp site, took two additional polyps out and did an endoscopy to ensure my upper and lower GI track were clear, and it was and the two additional polyps were benign. Through all this the serve muscle pains persisted and Hospital moved me to a patient room and out of the ER. Over the next several days, February 4 thru the 11th Hospital cleared me of everything they could test for, over 85 different tests were ran based on MyChart. All my blood counts were all over the place, WBC were 19,000, Platelets were nearly 700, my sedimentation rate reached 64+ and the server muscle pains persisted and I was basically incapacitated during my entire stay at Hospital. Hospital had several specialists seem me from Internal Medicine, Infectious Disease, Neurology to Rheumatoid ologist and none of them found anything wrong with me other than my COVID anti-bodies were enormously high with not signs of slowing down. The conclusion by each of the specialist is that my symptoms all point to an Adverse Level 3 Inflammatory Reaction to the first COVID Vaccine shot. The Infectious Disease specialists emphasized that I DO NOT get the second vaccine shot since it would like have killed me. (We had cancelled my 2nd shot, scheduled for February 3, 2021 via Cancer Center the week of January 30, 2021.) Hospital concluded that they could not do anything further for me since all their extensive testing all came up negative other then the COVID antibody levels and started me on the same steroid via IV on February 10, 2021 and on February 11, 2021 I was released from Hospital with a 28-day gradual reduction of the steroid over that timeframe to see if the COVID antibody production would simply stop. They had no other recourse or follow up with for any of the specialists. I?m on my own at this point and scared. To help with the inflammation the only thing my wife and I saw we could do is see a health and well Doctor to try and purge myself of the inflammation and assist my bowel and liver health with trying to rid me of the vaccine and hopefully the antibody production. I?m on a strict diet and taking supplements to assists in the reduction of inflammation and cleaning my system out. Starting today, February 18, 2021 I start stepping back on the steroids prescribed by Hospital and praying that the symptoms and pain simply go away but I?m still having night sweats, weak and shaky.

At 6pm on day of second vaccination the patient suddenly developed a fever, HA, and widespread myalgias. His fever has been from 100f to 104f. He has been alternating Tylenol and ibuprofen to bring down the fever, then it will go right back up. He was covid tested today and was negative with a rapid covid test.

Tongue and gland swelling, fatigue, joint pain, chills, nausea, redness, soreness at injection site. Symptoms started approximately an hour and a half to two hours after injection. Symptoms lasted approximately three days then tapered off.

Puffyness on upper right chest one day after. Subsided in a day and then a slight painful (like a sunburn feeing) point which seemed to be on a lymph node site near collar bone for a couple days. Then on the seventh day, redness and swelling on upper chest in same area. Got worse for two days then began to get better. Spot grew initially but then stopped growing. Slightly itchy, slightly painful, and very warm on second day.

delayed cutaneous hypersensitivity--red lesion, slightly swollen, itchy, some heat/tingling at site of injection

Moderna COVID-19 Vaccine Headache, body aches, chills, exhaustion, pain in left shoulder and arm pit, swelling in left armpit

Inflammation in my right hand, and rash in one finger. Not sure if the vaccine caused this. Also I felt bad for two days, and got mucus.

During the first and second day, my upper left arm was slightly tender from the shot. When that pain subsided during the second day after the shot, I started to get some swelling and pain in my left armpit. Discomfort was such that it interfered with my ability to sleep through that night. The following day (Day 3 after injection) the discomfort mostly subsided but still has not completely gone away. Currently on Day 6 after injection. No treatments or medications have been applied to alleviate the issue.

Skin below eye (near sinuses) was swollen, red, and tender to the touch Tuesday morning. On Wednesday morning it had spread down to his upper lip and across his nose to the right of his face.

Hives at neck and right side of back accompanied by extreme itching/burning-36 hours after, increased zyrtec dosage; swollen face-16 hours after; metallic taste-onset was 4 hours from inject and persisted for 7 days; pimples/white heads on left arm-16 hours after injection and persisted through day 12; intermittent tremors/shaking hands-6 hours after injection and persisted through 48 hours; mental confusion/fog-4 hours after injection and persisted through 48 hours; left arm numbness from injection site to wrist-4 hours after injection, episodic persistence through day 4.

Mother reports veteran received vaccine and they returned home. Drive is approximately 2 hours. Mother noticed that veteran had noticeable swelling to bilateral lower extremities, especially in ankles and feet. Mother reports there was no swelling prior to vaccine. No other side effects noted by veteran. As of today, 04/05/2021, mother reports he still has swelling to lower extremities.

"Moderna COVID-19 Vaccine EUA" Large Swelling and pain on left side of the face (Cheek). Swelling noticed about 5 hours after the vaccination, its about 20 hours passed swelling got increased and unable to chew. Took 50 mg Diphenhydramine HCl (allergy medication) and no improvement so far.

Eight days after first shot the right elbow has developed a warm, itchy rash. Topical hydrocortisone and Benadryl cream helps with the symptoms. There has been a red bump about 1 inch diameter as the center of the reaction, with lighter itching radiating about an inch or two from that location.

Received Moderna COVID vaccination 4/1/21. About 27 hours later, he felt muscle spasming across his chest. He then developed neck pain, tingling that goes into right and left arms/fingers. Was started on oral steroids by his PCP on 4/6/21. Given worsening symptoms and new development of urinary retention. Patient was admitted to Hospital 4/8-4/11. Suspected to have cervical transverse myelitis. Re-admitted 4/12 due to worsening generalized weakness, significant numbness, gait/coordination issues, and several falls. Differential diagnosis includes guillain barre syndrome vs. transverse myelitis. No MS on brain MRI. No cord lesion. Treatment included IVIG 0.5g/kg daily x 4 days, B12, 1 mg IM daily x 3 days. bilateral neural foraminal stenosis at L5-S1. 4/7: MRI cervical spine: Small focal area of increased T2 signal within the central cervical cord at the C2 level without associated postcontrast enhancement. A demyelinating disease is leading differential consideration. 4/11: MRI brain: normal, no de-myelinating disease; MRI C-spine: severe cervical stenosis with flattening of spinal cord but no cord edema/enhancement.

I had a flare of my arthritis symptoms. My right thumb was swollen and still is swollen, pain in both knees, both elbows, both wrists and both feet.

Fever, chills, aches, difficulty breathing, confusion, shaking, Swollen joints hands, neck, throat, and tongue lasting from 4/15-4/18. Convulsions began 4/16-4/17. Treated with benadryl and ibuprofen and Tylenol and albuteral inhaler.

CC: patient was watching TV as reported by his mother. started seizing and having difficulty breathing. EMS was called for transport. On arrival to ED, patient was breathing 60-70 BPM, tachy at 135-140 sinus rythym. B/P stable at 140's/90's. his pupils were equal and reactive to light. no response to aggressive sternal rub. slight seizure like activity with arm and leg jerking. Ativan IVP given Patient is on non-rebreather sao2 at 90-100 fluctuating. IV established. he desats to 80-85 on room air. Has frothy sputum from mouth. RSI performed with succs and versed to secure airway and ventilate patient. 7.5 tube placed with one attempt at 27/teeth. verified via direct auscultation and capnography. Tube secured. maintanence medications given to ensure sedation. transfer initiated and airmed launched. Dr. accepted. patient left building at 1940 via airmed. Patients labs (electrolytes WNL) normal wbc. D-dimer at 1500. suspect for PE or flash pulmonary edema although his breathsound are clear bilateral. 18:10 03/27/21. BP: 124/89. MAP: 100. HR: 135. RR: 54. O2 saturation: 94%. Temp: 99.2 F. Pain level now unable to obtain due to patient condition. --20:05 3/27/21 Weight: 81.6 kg estimated

Moderna COVID-19 Vaccine. I got a rash all over my body (legs, back, eye brows, arms, pelvic area. Very itchy, redness and some swelling. After 11 days it is mostly receding, but still itches some.

About 24 hours after receiving the shot I am experiencing some swelling and extreme itching in hands and fingers. As time has progressed the swelling has gone away entirely but I am now experiencing itching along with visible hives on both wrists, inner thighs, and inner arms at the elbow.

Patient's partner called reporting that the patient was experiencing severe nausea and facial swelling. Patient immediately instructed to go to emergency room ASAP and follow up with providers office ASAP. Called the patient today @04:05pm with no answer. Left voicemail asking patient to call me back ASAP. Provider and Practice Administrator notified of adverse reaction.

Swollen tongue and throat. Diagnosed as angioedema. Treated with epinephrine, benadryl, oxygen, and IV lines. Took a few days to recover.

Started with red rash which progressed to being warm to the touch. Initially managed by hydrocortisone cream and antihistamine. By day 3, progressed to whole arm swelling, rash, and hit to the touch. No pain. Went to ER for fear of cellulitis. IV vancomycin and ceftriaxone given (3 doses and 2 doses respectively). Discharged on oral doxycycline and cephalexin.

Patient reports that there was no pain at injection site the day of injection. Reports feeling a "crook in the neck" the evening of receiving the vaccine. States he woke up the next morning, 4/14/21 with a very painful L arm, couldn't lift it and no strength. Left arm is still painful and with reduced strength as of 4/28/2021. States arm is still swollen but has improved. Patient saw his primary care provider (not at our clinic) on 4/23/2021 and was given a shot of Toradol for pain. Patient also kept existing appointments with neurosurgery and pain management for failed back surgery. Neurosurgeon advised it could be nerve injury and that it will heal over time. Told patient that nerve in arm could be in a different location due to his history as a body builder. Patient states arm is better but still painful and weak.

On 4/13 Patient underwent aortic root replacement with saphenous vein graft reconstruction of the right coronary artery. He had no prior coronary disease. This operation was done for an enlarging aortic root aneurysm in the setting of Marfan syndrome. The right coronary was anomalous and needed vein extension for reimplantation. He recovered very well and was seen in our clinic on 4/23, with no unusual findings. He had a normal echo, EKG and DVT study performed. On 4/28 he had his first Moderna COVID19 dose. on 5/1, he developed malaise, myalgias, painful lymph nodes, chills, and chest pain. He called my clinic and was instructed to go to the ER, but then felt better and didn't go. He was then found unresponsive later that afternoon and was pronounced dead on arrival of EMS.

Visited ER on 5/3/21 with symptoms of shortness of breath, cough, fatigue, oxygen sats 90-91% on room air, tachycardia (HR 114), BP 182/127

About 5 days after injection i felt left lower leg swelling on the lateral side of my shin with 2 areas of point tenderness and muscle pain. The area still is sore after a lot of staying off my feet and using ice packs on the area. I do an extreme amount of walking at work and am wearing brand new running shoes so the footwear shouldn't be an issue.

Severe swelling and bruising of right arm started on day of injection. Pain and swelling increased following day, Then on Friday evening I had a heartache.

Left upper eye lid swelling Right cheek swelling Developed allergy from Peanuts after for Covid vaccine shot - Upper lip swelling stayed over 24 hrs.

I had no noticeable issues with my first dose of the Moderna Covid-19 vaccine. I had the following issues after my second dose (April 29, 2021): Day 2 (April 30), 28 hours following injection, I experienced an internal feeling of ?jitteriness?, shortness of breath, and accelerated pulse. Pulse oximeter showed my oxygen saturation dropped to 92 percent (my normal is 98-99) and my resting pulse rate increased to 120 bpm (my normal varies from 66 to 75). Aforementioned symptoms subsided after 6 hours. Day 3 (May 1) following injection, local swelling and pain in muscle at site of injection (upper left arm). Arm swelling and pain subsided by Day 7.) Day 4 (May 4), noticed two swollen lymph nodes (size of pea and small marble) near collar bone area of neck (same side as injection). Day 31 (May 29), both lymph node swellings still exists (as of this reporting) though not as prominent.

Tightness in chest. Shortness of breath. Sore jaw. Pain in left arm. Called 911 and paramedic took EKG and informed me I was having a heart attack on the way to the hospital. Once at the hospital they measured my TnT-Gen5 and the baseline was 2658 ng/L with another test taken an hour later showing 2873 ng/L which led to additional tests listed in box 19. Final diagnosis was perimyocarditis and I received a prescription of Colchicine 0.6 MG to be taken twice a day for 6 weeks and then follow up with a cardiologist.

One week after 2nd dose noticed left ankle and calf area swollen much larger than right ankle. Slight pain and tightness in left upper chest, upper back, and into left arm occurring often. Symptoms have persisted for over a month. Was checked for a blood clot in left leg but results were negative. Seeing my doctor for additional tests, probably an echo next. Symptoms have persisted daily since about one week after the 2nd dose. Concerned symptoms are consistent with myocarditis.

First injection no sides effects beyond a sore arm. Second Injection; Flu like symptoms starting at 5 hours post injection. Peaked with chills and sweats 16 hours post injections. Fatigue for the next two days. Cold sore appeared 2 days post injection. Tinnitus noticed (double pre-existing tinnitus levels) 20 hours post injection. Tinitus still present over 30 days later. Checked permanent damage box because I have no way to know if the tinnitus will subside. The tinnitus is what reminded me/prompted me to submit this.

Around 6:30 p.m. my skin started to burn all over my face begin to swell shortly after that my tongue and throat begin to swell I feel pressure on my chest I can barely breathe when I was put into the ambulance I passed out when I woke back up the symptoms seems to have gotten worse the EMT called in a head to the hospital and ask what to do she was told to give me an EpiPen as we got closer to the hospital I begin to shake and tremble uncontrollably that lasted for at least another 30 40 minutes after being admitted to the emergency room my diagnosis was anaphylaxis.

SOUGHT CARE AT ER WITH C/O VOMITING, NOT BEING ABLE TO WALK, CHILLS, FEVER, COUGH, CONGESTION. NEGATIVE FOR COVID-19. ADMITTED FOR IV ANTIBIOTICS AND SUPPORTIVE OXYGEN THERAPY. DISCHARGED 2 DAYS LATER. TREATED WITH ZITHROMAX IV, ROCEPHIN IV, O2, ACETAMINOPHEN, HIGH-FLOW NEBULIZERS

Patient presented to the ED and was subsequently hospitalized for severe sepsis and pneumonia within 6 weeks of receiving COVID vaccination.

On June 21, at approximately 8:30 a.m., my husband started with chest pain going thru to his back, he could not take the pain, saying that he felt very bad, which we had to take him to the nearest hospital to the emergency room. On the way he vomited, having sweats and arriving at the hospital he said that he could not walk, I brought him a wheelchair and he went into the hospital telling me that one foot felt cramp and numb that he could not move it, after the doctors checked him and two hours later he told me that he no longer feel both legs. Since that day he could not move from his stomach down to the tips of his feet, And after a few days and several tests they could not find any reason why he had paralysis, the doctor said that it was a syndrome called Guillen Barré and to date he is still hospitalized without being able to move his feet and waiting for help to receive therapy since we do not have the monetary resources for these services.

7/19/2021: Patient came to ER due to weakness, diarrhea and abdominal discomfort. One week prior he developed decreased appetite as well as abdominal cramping with increasing pain. Patient tested positive for COVID on 7/19/21. diagnosed with: sepsis due to COVID-19 infection, bilateral pneumonia 7.25.21: discharged home. Note: COVID-19 vaccinations status: S/P 2 doses of Moderna Vaccine in April of 2021

101.3 fever on and off overnight, chills, severe body aches, headache, injection site pain and swelling along with lymph node swelling left armpit. At 24 hrs no treatment, clinic closed for New Year?s Day. Intake of extra water, bananas for dehydration and acetaminophen for fever.

Abdominal cramps and bloating starting approx 24 hours after vaccine lasting 1-2 days, fatigue for 2 days, deltoid soreness with movement for 1 week, tender left axillary adenopathy noted Monday Jan 4th.

Injected in the right arm. Woke up this morning to the right underarm lymph node swollen and tender to the touch. No redness, no rash, not warn to the touch. Fatigue and body aches also accompany the adverse effects this morning.

Days 3 through 10: ipsilateral axillary lymphadenopathy and tenderness as well as tenderness over left chest well inferior to the axilla. No treatment. Day 8: Sudden onset of a localized 3 cm cutaneous rash (erythema, pruritis, induration) at injection site in shoulder. Rash lasted for 24 hours. No treatment. Day 11: Deltoid exercise induced 2cm cutaneous rash (erythema, pruritis) at injection site in shoulder. Rash lasted 10 minutes.

I have a red bump on my arm that is a knot and tender to the touch or painful when touched. It is very itchy and had a headache for the past few days

Headach, still neck and light sensitivity soon after injection. These symptoms lasted about 24 hours. After these abated then significant swelling of left arm pit and ringing in both ears for 10 days now.

I began with chills on Weds. morning around 10am that only got worse not matter what I did. My arm continued to hurt but I thought it was just the injection pain. I then began to exhibit a temperature (100.3) and to feel fatigued and had a bad headache by late Weds. afternoon and evening.(These symptoms were similar to those I suffered when I had Covid back at the beginning of August, minus the throat pain and breathing issues I suffered. By that night my arm was throbbing and I had fevers that ran as high as 102.7 and suffered multiple night sweats. My wife noticed swelling in my upper left arm and on Thurs. I contacted my Dr. who directed me to take tylenol and apply ice to the swelling. Which I did all day Thursday. The fatigue, fever and headache persisted all day Thursday and my arm began hurting more. I began to notice discomfort in my underarm (left) and my wife (a nurse) noticed it was swollen (softball size), warm to the touch and extending into my left pectoral muscle. I began applying ice to this area also but it had no impact. Contacting my Dr. on Friday about the new swelling, she examined me on Fri. afternoon and prescribed me Cephalexin, Medrol Dose Pack steroid, and over-the-counter Clariton allergy medicine, which I began Friday night. My fever began to subside and by Sat. morning my arm pain began to lessen and some of the swelling went down. Now Sunday morning, the fatigue, fevers and headache have gone, and most of my arm pain in gone (still tender to the touch), I still have some swelling in both upper left arm and Underarm pit. Dr. feels this was and allergic reaction and recommends I do not get the second injection.

On Friday, I had the second vaccine covid 19, at 9;00 am at the left shoulder and after 12hours at 10:00 I started to feel the symptoms was light fever ,chills, headaches, body aches. Symptoms that was high concern: shortness of breath, vision discomfort due to the light, high blood pressure, extremities(hand and feet) swelling accelerated pulse ,chest pressure. This lasted on an off proximally 3 to 4 hours. Saturday afternoon at 3pm once again heart rate went up and pulse lasted 1 hour .The entire Saturday was feel the primary symptoms with chest pain . Today Monday I woke up with pain at the left clavicle bone and found a lump that hurts and radiates to the chest and increasing in size .

Approximately 30 minutes after vaccine given to patient, patient c/o dizziness and flushing. Patient's arm warm to touch with significant swelling. Patients vitals immediately taken and within normal limits. Patient advised to wait 15 more minutes. Within 10 minutes, patient was no longer experiencing dizziness and states that he "feels much better". He also stated that he may have been "just having anxiety" Advised by PA to take antihistamine. Patient voiced understanding.

Pt several hours after vaccination experienced fatigued and malaise. Pt. went to sleep at home approximately 6 hours, upon waking had severe facial swelling, global itching, and continued malaise and fatigue. Pt took diphenhydramine, 50 mg. Resolved itching and swelling to a point where pt did not need to take additional antihistamines. Went back to sleep and slept for approximately 10 hours. 2nd day, called out sick from work, experienced malaise and fatigue, and slept for additional 6 hours during the day. Experienced fatigue and malaise for the next two additional days. Experiencing continued soreness in right shoulder, experienced with movement, not debilitating and does not affect activities of daily living.

About 24 hours after receiving the vaccine, I started with a dull headache (scale of 1-5, 5 being the worst, it was a 1), and onset of chills (scale of 1-5, 5 being the worst, it was a 3 )and flushing. The chills lasted about 4 hours. About 36 hours after receiving the vaccine, I noticed swelling of my lymph nodes under my left arm. (scale of 1-5, 5 being the worst, it was a 4) It is about the size of tennis ball, it is causing discomfort and hard to sleep. It is painful. The flushing, headache and chills all went away.

I don't have lot number or dose number. It was a Moderna COVID 19 vaccine. I got my first dose on Jan 11, 2021, suffered light headedness the first day, and two days later, while at work I felt like I was going to pass out several times. I also suffered low grade fever and swelling of my lymph glands in my throat. I took my booster on Feb 8, 2021 at 1310, the next morning I was suffering nausea and overall malaise. I waited until fever started to take alternating tylenol and motrin. I was very weak, freezing to death, and fell asleep about 6 PM fully dressed with my coat on under covers. I woke up at 9 pm, still feeling horrible, wondering if it was 9 am or 9 pm, and went back to sleep until 715 am this morning with body feeling like it was ran through a hamburger grinder, no doubt a result of the shivering yesterday. I have not had fever today, but still feeling a little nauseous about eating anything.

Developed a fluid-like pocket under my left arm as well as in the area of my left collar bone. They were there for about 3-4 days and then slowly went away. The one on my collar bone was slightly tender, and that is what caused me to notice it. The one under my arm was not tender at all.

Injection site: pain and tenderness, swelling, lymph node swelling, redness General: Fatigue, headaches, muscle/joint pain, feverish and chills without an actual fever All side effects have been very manageable.

Acutely painful & swollen elbow after shoveling snow 2/2/21 that was drained 2/8/21 and labwork showed inflammatory process without infection. Severe and debilitating widespread muscle cramps, mostly legs /hamstrings, low grade fever, extreme fatigue. Antibiotics started 2/8/21 while lab for Lyme pending. Condition worsened until Lyme ruled out and prednisone started 2/16/21 providing some immediate relief. Onset of systemic inflammatory process remains mystery.

Extreme pain in left shoulder, inability to move left shoulder/arm, swelling in arm, extreme fatigue, extreme muscle pain in upper back.

Pneumonia, hypoxemia, Dyspnea, Tachycardia,SIRS, increased lactic acid level, dehydration,fever, HTN, hypomagnesemia

On Wednesday, February 24th I received the first dose of the Moderna vaccine. On Friday evening I developed joint pain and swelling in my left should blade, my right wrist and my left large toe. The pain in my shoulder and my wrist is excruciating and I have not been able to sleep properly. I have very limited mobility and cannot grip with or use my right hand. I started taking 200 mg of ibuprofen on Friday night with food but it did not seem to reduce the pain. Through the night that night I increased my dose to 400 mg and felt some relief in my shoulder but my hand is still very painful. My toe is uncomfortable but tolerable. I used tiger balm several times on my wrist but that did not help. I also put it on my back and it seemed to help as long as I did not move. If I moved a felt a very sharp pain under my shoulder blade. I used ice on my hand and it only benefited briefly. I couldn't apply it at night and therefore couldn't sleep. I am unable to move or function as I normally would due to the sharp pains in my back/shoulders and right hand. Unable to function without assistance and cannot go to work.

onset started as itchy around armpits around 10:15pm. Then hands, eyes and feet started to itch. Then feet and fingers started swelling, and about five minutes after swelling started, he states he was swollen all over. Nose, ears, eyes were all swollen. He states that after the swelling he started developing hives all over and redness all over. About 30 minutes later he became short of breath and went to the ER at around 1145 pm.

fever to 104, thrombocytopenia. Started 2/28/21. had leukocytosis, near syncope and high recurrent fever with all cultures negative. Is improving as of 3/2/21.

Fever of 102.4, treated with ibuprofen and acetaminophen since vaccination. Started on 3/6 Bone, joint, and muscle pain. Started on 3/6 Sore throat, swollen lymph nodes in neck, ear ache (left). Started on 3/7 Cough and chest pressure, breathing difficulty. Started on 3/7

angioedema; swollen glands below the jaw; dry mouth; canker sores; thrush; a metal taste in his mouth; swelling of lips, tongue and gums; Rash; A spontaneous report was received from a consumer concerning a 51-year-old, male patient, who received Moderna's COVID-19 vaccine and experienced angioedema, swollen glands below jaw, dry mouth, canker sores, thrush, metal taste in mouth, swelling of lips, tongue and gums. The patient's medical history was not provided. Concomitant product use was not provided by the reporter. 0n 06 Jan 2021, prior to the onset of symptoms, the patient received the first of two planned doses of mRNA-1273 (Batch number: unknown) for prophylaxis of COVID-19 infection. The patient developed symptoms after the first dose like dry mouth, canker sores, swollen glands below the jaw, swollen tongue, thrush, a metal taste in his mouth, and swollen lips. On 05 Feb 2021, the patient received the second dose of two planned doses of mRNA-1273 (Batch number: unknown) for prophylaxis of COVID-19 infection. Nothing new happened after the second dose. On 29 Feb 2021 (the date will be confirmed) he went to ER received steroids, Benadryl and Pepcid. They treated him for angioedema. Most of the symptoms went away except for the swelling of the gums, rash and metallic taste. The outcome of the events, angioedema, swollen glands below jaw, swollen tongue and lip, dry mouth, canker sores, thrush, swelling of lips, tongue and were resolved. The outcome of the events metal taste in mouth, gums and rash were unknown.; Reporter's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

51 y.o. male from Facility. The patient was seen at his primary care physician's office for some left facial swelling. Apparently, he started getting more short of breath while he was there. He was sent in by EMS. His sats were initially in the upper 80s at his primary care physician's office. He denies any symptoms of URI, but does state he has a long history of COPD. The patient was given some DuoNebs and supplemental oxygen in the emergency room and shortness of breath basically resolved. However, he did have very significant left facial swelling. His CT did show facial cellulitis with possible abscess, but no fluid collection. His white blood cell count was almost 25. He had been having fevers at home. Because of all this the decision was made to admit for IV antibiotics. When I saw the patient, he was willing to stay for IV antibiotics for a few days. 3/11/21 remains hospitalized

Immediate face redness and swelling. Later in evening no sleep and heart racing, next day no energy and body soreness. Day 2 heart racing at night and no sleep. Day 3 I was able to sleep through the night.

Severe swelling of left arm, all the way down slightly below the elbow and redness wrapped almost completely around to the front on my arm on both sides. Extremely hot to the touch, Extreme chills approximately 12 hours after getting the shot for roughly 12 hours. Slight headache and aches in my joints, knees , ankles, fingers, etc. this was during the second day and subsided by the evening. Swelling, redness, and hot to the touch lasted numerous days and got worse for two days but subsided significantly after taking Benadryl but redness and slight heat remained for approximately 5 days.

Minor tightness/swelling for 24 hrs after 1st shot. (Not what I?m reporting here.) Exactly one week following first shot, injection site became red, itchy and slightly swollen. Applied Eucerin skin lotion and no longer itchy, less red.

I received the shot Friday and early Saturday am around 3. I woke up with the chills, was warm etc.. Through out the next day all day and night , i was in bed, with muscles pain, chills and nausea and was so tired. The fever would come and go. I took Tylenol for treatment. I had no appetite until , i woke up Sunday morning around 9. Got up , ate and later Sunday felt much better. Monday, back to feeling my old self but i noticed a large swollen lump under my left armpit when i showered. In the left arm i was injected. Today , the large lump, its still there rather large.

The second evening after having my 2nd Moderna dose my left arm completely froze up. I was only able to lift my arm above my head with assistance from my right arm. Eventually I was able to lift my arm without assistance and the same phenomena happened the third evening where my shoulder was frozen and immobilized. The frozen shoulder has abated but there is still moving poi's of major swelling in the upper arm. There has been persistent but slowly abating symptoms of deep soreness, arm weakness and weak grip strength. Swelling persists in the upper front portion of left shoulder. I can not do extended tasks with the arm because it does not have strength nor stamina.

The only difference was fever blisters around mouth and in nose...regular side effects lasted about 24 hrs, fever blisters formed that evening through today 03/28/21

Facial swelling in eye, cheek, lips began on one side of face approximately 36 hours after vaccination and spread to other side of face throughout 2nd day after vaccination.

After approximately 12 hours I started feeling aches and pain of body, joints. Also, headache started developing at same time along with mild fever. All symptoms continued for approximately 36-40 hours. Then approximately 40 hours later my lymph glands under my left armpit and in my neck became swollen and painful. Sore throat accompanied this condition.

Fatigue, body aches, headaches, chills, lymph node soreness. Took Tylenol for the headaches and slept as much as possible for 2 days.

Itching, swelling and knots at the bottom of my feet and the back-side of both forearms. Small hives on my forehead. Excessive runny nose. - 3 days

reports enlarged lymph node, headache, and arm pain since the day after his immunization. He reports headache and arm pain have been intense at times, but reports some relief after taking acetaminophen. He reports these symptoms have disrupted daily activities at times.

I experienced "Moderna Arm" on the day following the injection, but it subsided after a couple of days. Eight days later, though, it returned (swelling/redness/milder pain) -- accompanied by swelling in my right ankle and tightness/some tingling/mild pain in my right ankle/upper calf. I suffered a blood clot for the first time in each leg in early November; the more serious of the two was in the vicinity of my upper calf in my right leg. In December, I began to experience sensations in my right ankle that were similar (albeit more intense) to what I later experienced after my vaccine; the post-vaccination symptom in my right calf was also similar (but milder) to what I had experienced from the DVT.

Extreme lymph Noyd swelling under arm approximately baseball size which then pushed in behind my chest muscle this happened 4 to 5 days after the shot and after the high fever went away

Pain starting in both legs the day after the vaccine(Tuesday) and fever of 100.6 Later that night the fever broke and the pain persisted in right leg . He took tylenol to ease pain. Wednesday the pain persisted and he continued with tylenol . Thursday am woke to find the leg was swollen and painful to the point of going to the er.

I developed chills 14 hrs after the 2nd dose of the Covid-19 vaccine, then later also experienced a low grade fever of 99 degrees F. Throughout the second day, I experienced headache and fatigue that did not alleviate until the morning of the third day. After the headache and fatigue alleviated, I noticed a large swollen gland under the left armpit. This slowly diminished over time and was mostly gone by the fourth morning.

Within five minutes of receiving vaccine I broke out in a cold sweat and was dizzy. That lasted for about ten minutes. The next day I woke up to pain running from the right side of my jaw to my right ear. The injection site in my right arm was more sore than any other vaccine shot I have ever had. The glands in my neck were swollen and my right side shoulder and neck area were sore. I experienced waves of fatigue over the next four days. The pain to my ear that seemed to mimic a really bad ear infection continued for six days. I went to the minute clinic at the Pharmacy where I received the shot and was checked out. There was nothing wrong with my ear and they could not find anything wrong with me other than my glands were swollen and I had a general amount of swelling on the right side of my next going into my shoulder. While the pain in my ear has lessened some it is still there now eight days after the vaccination. I have also experienced some GI issues. I am extremely regular and do not have issue going to the bathroom. My gut was not normal and I did not have normal bowl movements for more than a week. I also have had something akin to a rash on my arms that looks like prickly heat. It seemed to me that my immune system overreacted to the vaccine. I have contended for months now that I had Covid back in March of 2020 right before the shutdown. I believe I caught it during business travel at the very beginning of March 2020. My concern is whether I should get the second Moderna shot if my immune system is already this revved up with antibodies.

Previously submitted VAERS Report detailing disequalibrium and initiation of pronounced persistent ringing ears post Dose 1 (#028A21A) Moderna on 4/2/2021 Received Dose 2 Moderna (#003C21A) on 4/30/2021. Received Audiology Test 5/3/2021 on 5/10/2021 early AM - in additional to 40+ dB 12.5 kHz narrow band L ear, and 14 kHz narrow band R ear ("normal" hearing 2-8 kHz, and 18-20 kHz) emerging persistent subjective "Low Tone" - sound like deep machinery humming in distance/ through the walls. Grown incrementally louder last 2 days. Very significant experience. 100% persistent. Do not wish on anyone. 5 weeks of high-pitched ringing (as noted in prior VAERS, now this additional audio phenomenon of "low humming machine." Sudden onset. Very healthy, normal BP. No prior ringing ears. No ringing ears in 80+ year old parents, nor 5 siblings. Had subtle facial swelling (lymphatic) for 5+ days post Dose 2.

Approximately 4 hrs after vaccine administration, dark, red, raised rash appeared on torso, arms, buttocks, and legs. So severe that dexamethasone started. Rash did not improve for weeks and steroids continued during that time. Patient noted to then go into congestive heart failure, had 2-3+ pitting edema, "ground glass"/pulmonary congestion in lungs, rapid A-fib with RVR 170-180s. treated at Hospital with admission from 5/15-5/17/2021. Patient complained of chest pain and trouble breathing starting 5/13/2021. Patient has mostly recovered, and is at home now. Now on high dose beta-blockers and eliquis for the new onset A-Fib.

swelling in left arm, severe pain in neck, shoulder, and arm upper area. Not sure if its becausethe shot was given very low in the shoulder.

I woke up early in am with 3rd toe on left foot painfully swollen and red. I took ibuprofen for pain and continued to work Thursday, Friday, and Saturday. I came home Saturday night around 8pm. I could barely walk the pain was so bad. Took my boot off and saw that the redness was spreading to the top of my foot towards my ankle. My wife took me to the ER. I was diagnosed with cellulitis and prescribed Cephalexin 500mg 4 times a day for 10 days. The infection resolved after finishing the antibiotic.

Chills,,pain on the injection site, the day after I experienced facial swelling it got worst the fourth day after and went to emergency room . After being examined , I was given prednisone and sent to dermatologist same day for further examination of pustule development. The dermatologist took some culture of the puss and punch biopsy. The culture was negative for what they were looking for and the biopsy proved inconclusive and pathologist did not See any specific that would support reactions to the vaccine.

Patient was first diagnosed with bursitis at his pcp and sent home. Patients elbow was swollen and referred to urgent care by the pharmacist pharmacy. Patient was seen by Dr, and found to have a blood clot when doctor tried to aspirate the elbow. Patient has fully recovered at returned to work

Pt admitted for L lower extremity DVT and bilateral extensive PE's. No known medical history, family/personal history of clots, no known clotting risk factors. Pt noted swelling in his leg 2 days after getting second covid vaccine and later developed SOB leading to presentation.

Blood clot / deep vein thrombosis in left leg developed less than one month after 2nd dose. Acute pain behind left knee, muscle ache radiating through calf to foot. Swelling. Warm to touch. Felt like a pulled muscle for a week before doctor visit.

Inflammation of lymphglands along the neck. Possible myocarditisis. Uncontroled Hypertension , atypical chest pain.

Swollen glands, both ear drums are hurting, break out in hot sweats but cool down 20 mins later, have headaches and a slight fever

Eosinophilia, low grade leukocytosis, monocytosis, without neutrophilic predominance patient received vaccine on 6/17. These were normal when checked 6/3 monocytes and wbc normal when check 6/16 (eso not checked 6/16) Next time these labs were check was on 6/25 - WBC and eso - elevated eosinophils & monocytes remained elevated until 7/13 WBC still elevated more substantial now - maybe be increased for other reasons now Inpatient from 6/27- to present Patient admitted for other reasons -

?Moderna COVID- 19 Vaccine EUA? Patient received vaccine on 12/23/2020, complained of swollen lymph notes on 1/1/2021. Patient also experienced chills, fever 12 hours following vaccine administration.

Patient developed right facial swelling and right parotitis approximately 18 hours after vaccination.

Fever x 3 days 102.1 (highest temp) , chills, headache. Swelling of hands and feet with rash/redness on hands and feet. That started on Jan 27 2021 x2 days after vaccine. Hasn't subsided yet.

Severe myalgias, fatigue, headache, chills began 6 hrs post vaccine; by the next afternoon, fever to 103.1, extreme fatigue, headache, myalgias, altered mentation, right arm pain, swelling, redness; sought medical attention - prescribed prednisone 20 mg daily; fever defervesced late afternoon , but returned the next morning to 101.2, with improving headache, fatigue, myalgias; by 1/24/21, most symptoms except fatigue and local injection site pain had resolved; now still mild fatigue and mild arm pain

Day #1 minor pain in left shoulder Day #2 felt fatigued, headache, chills. Day #3 showered at 9:30 pm and noticed significant swelling under my left arm and into my left chest area. I had increase in neck pain on left side.

The patient had a very severe side effect profile from the second dose of vaccine: "worst I've ever felt" with myalgia, headache, fever and fatigue. This subsided and then on day 3 he developed severe substernal chest pain and came to ER where his hs-cTnI was > 2000 ng/L and peaked at 6700 ng/L. His ECG, echo and cardiac cath were normal but MRI showed evidence of myocarditis with mild left ventricular dysfunction. He is doing well clinically and we are managing expectantly. This appears to be immune mediated myocarditis from the Moderna vaccine

Patient within 5 minutes reported having tingling in his hands and swelling in his hands. Vitals at 9:19 am BP 132/80, O2 sat 96%, HR 102. Dr present in the hall and observed patient. We decided to watch and wait. A few minutes later, patient started clearing his throat. Patient stated "It feels like there is something in my throat and it is getting harder to breathe". Patient has allergy to bee venom, particularly ground wasps. Dr who was on-call called to the room. Ordered 0.3 mg Epi pen and 50 mg Benedryl IM at 9:37 AM. Given. Patient stated he felt better immediately. Hand swelling started going down. Sensation of throat discomfort and difficulty breathing subsided. Patient asked to wait another 30 minutes for observation. Patient continues to state he feels fine "just a little drousy from the benedryl".   Vitals at 10:33 am HR 100, BP 122/80, Pulse ox 98.   Dr is allowing to discharge to home right now where patient states he has more epipens.    

Patient with swelling to his L axillary and breast. Patient currently taking tylenol for discomfort. Informed to follow up with MD.

Lymph nodes of swollen where the ear meets the neck Next Day Sunday 2- 7 Monday 2-8 rash & Body covered in Hives

From OHS: Lymph nodes, pain in shoulder, lumps in groin area, is not sure if it is related. Noticed these symptoms since the injection. Did have a fever after the vaccine. Second dose was almost 2 weeks prior. Patient received #2 1/21. Had fever, fatigue, HA x24-48 hours post vaccine that have resolved. Localized injection site pain and induration L deltoid have decreased. PMH: R rotator cuff tear with surgical repair 2/2020. Since 1/27, c/o severe pain in R shoulder radiating to right neck w/ possible muscle spasms. Patient feels pain is localized to the trapezius muscle. Denies numbness, tingling, weakness in RUE. Patient spoke w/ PCP yesterday and was prescribed Flexeril. Patient has taken Flexeril without relief of pain. PCP rec MRI if no resolution of R shoulder symptoms. Patient has appt with Ortho surgeon 2/9. Rec patient f/u with PCP for medical management and try to get sooner appt with Ortho if possible. Denies f/c, chest pain, SOB, cough, fatigue, diarrhea, ansomia, sinus congestion, rhinorrhea, sneezing.

Tingling of the face Obvious swelling of the face Itchy throat ER visit- Benerdry & prednisone, 4 hours observation. Symptoms receded

Guillain-Barré syndrome. So far hospitalized =X 7 days, on day 3 of IV IG with ICC line, then planned 3 days of high dose soleumedrol, then plasmapheresis Auto-immune hepatitis

Fatigue, headache, muscle pain, joint pain, chills, nausea, fever (101 highest) fever maintained for 48 hours. Lymph node swelling left armpit onset 24 hours after injection, still swollen and sensitive at 72 hour mark. Other than lymph nodes, all other symptoms came on at the same time just as I felt when I had COVID 19 March 11, 2020, date of onset of symptoms. Sleep, Tylenol, Zinc, Vitamins C and D. Symptoms began to improve at 36 hour mark. 72 hours after injections only symptom that remains is lymph node inflammation.

pt had typical 2nd dose symptoms 2-3 days after vaccine (low-grade fever, body aches, fatigue) which resolved, but the joint aches worsened daily. Seen 9 days after vaccine administration, he has inflammatory polyarthritis, with R hand significantly swollen, L hand mildly so; bilateral shoulder pain with decreased ROM, bilateral hip pain and spine pain. saying he can feel every joint - difficult to move around (unusual for this 52 yo male). He increased his ibuprofen to 800 TID and increased his tylenol to 1 g TID without relief. Pt was given a shot of steroids (SoluMedrol) on 2/27 with some improvement by 3/1, but not completed resolution of swelling, grip strength or pain.

About 4 hours following the 1st part of the vaccination (i.e. around 8:30 pm), I felt the skin of both my cheeckbones swelling and flaring up. By the following morning, I felt that skin area, as well as the area around both of my eyes to feel as if I had sustained second degree burns. Additionally, the skin around my eyes particularly, presented with extreme dryness and geriatric symptoms, such as wrinkling and streched thinned skin, as if I were an elderly person (over 75 years old, and not 52). The flaring/burning subsided after 4-5 days. However, the skin dryness around the eyes has persisted to this day (i.e. 5 weeks past the 1st vaccination). A day after the 2nd part of the vaccination, I felt moderate dizziness and headache, which lasted for about 24 hours. Also, light soreness and skin stiffening were experienced at the arm location where the shot was adminmistered.

Painful left-sided axillary, supraclavicular and posterior cervical nodes - initially came 3 days after second dose vaccine on Feb 1st. Pain improved after 4 days. Then pain and swelling in same sites have increased past 8 days. It has been more than 4 weeks since the last shot and painful multiple lymph nodes on left axilla, supraclavicular and posterior cervical nodes are persistent. (I am an Infectious Diseases Physician).

signs of anaphylaxis after eating granola.. full body itching, lightheaded, wheezing, shortness of breath, sensation of throat swelling up

I woke up the following day and felt an itching or irritation on the inside of both elbows. I discovered to pink, bumpy and inflamed areas, mildly itchy. This is all that I have at this point, aside from injection site pain, and maybe some dizziness or fatigue.

5 days after shot, had extreme arm pain and reoccurrence of low grade fever. Also later experienced extreme pain in right calf and left thigh. 8 days after shot, saw nurse practitioner who prescribed keflex for the arm and rest/ice for the legs. Arm improved but continued to experience low grade fevers every afternoon/evening. Also showed increase in resting heart rate starting the day after the shot from 55 bpm to 70 bpm 12 days later. Blood pressure also above normal levels

I have had swelling in my lymph nodes above the right collar bone near the neck. The size is approximately 2 - 2.5 inches.

Patient reports getting a fever blister the day after receiving the vaccine. Patient states that this does not bother him and he did not seek medical attention.

No reaction to first shot. Received the second shot the morning of 18 Feb, noticed some minor joint stiffness, minor pain and tiredness mid morning 19 Feb. Laid down at 16:30 and remained asleep until 0530 the next day. Unusual to sleep 13 hours. Later that weekend I noticed a bruise on my leg. I rarely bruise and had not hit my leg on anything. I ignored the bruise a couple weeks, but as it did not heal, continued to hurt and had swelling I went to my primary doctor on 4 March who thought it was a blood clot and sent me for imaging. They determined it was superficial thrombophlebitis and treated with antibiotics and heat.

Left leg below the knee swallon twice the size as right li eg happened on 1st shot started to go down. Second shot on 3/10/21 swollen once again even worse also area is red

Site: Itching at Injection Site-Mild, Site: Pain at Injection Site-Medium, Site: Redness at Injection Site-Medium, Site: Swelling at Injection Site-Medium, Systemic: Lymph Node Swelling-Mild, Additional Details: Patient reports lymph node under armpit feels swollen. He noticed injection site reaction within 1-2 hours of receiving vaccine, but has not experienced any other systemic reactions.

4 Hours After: Severe Headache 6 Hours After: Fatigue 8 Hours After: Fever, Chills 24 Hours After: Severe Lower Back / Kidney Pain Right Side 48 Hours After: Severe Lower Back / Kidney Pain Right Side, Swollen Lymph-nodes 72 Hours After: Lower Back / Kidney Pain Right Side, Swollen Lymph-nodes

ANAPHYLACTIC REACTION THE EVENING VACCINE WAS RECEIVED: DIFFICULTY BREATHING, FEVER, DROWSINESS, DISORIENTATION. 7 DAYS LATER: FEVER, PLAQUE PSORIASIS, RASH, BURNING/ITCHING SKIN, FEVER

Pt received 2nd dose of COVID-19 vaccine. About 8-12 hours later pt develeopd vesicles/pustules near injection site. The maculopapular rash was a diameter of approximately 8 inches. Pt further reports other areas on his legs, and in the medial thigh which waxed and waned. Pt has had a 3 day history of facial swelling, and orbital edema. Further states nodules on trunk and groin area. Pt has taken diphenhydramine with minimal relief.

I started to retain water and eventually gained 26lbs in the next week and ended up in congestive heart failure. Doctor was able to get water retention reduced and all is back to normal

pt says he when he woke up his right arm pit was swollen and it is still like this 3 days later. He is waiting for his PCP to call him back.

52-year-old male with no significant past medical history presenting with acute hypoxic respiratory failure and pancreatitis. Admitted to hospital on March 1, 2021 at Medical Center, for presentation of abdominal pain, elevated lipase and pancreatitis. Was airlifted to Medical ICU unit at a Larger Hospital on March 6, 2021. Was in the hospital until March 17, 2021 and was sent to Rehabilitation until discharge on March 26, 2021.

SEVERE! Headache for approximately 2 hours causing incapacitation. Swelling of a lymph node near left collar bone for 4 days (swollen to approximately 3x normal size. Swelling in left harm and fever for 5 days (swelling occurred in the area of my first vaccine and was approximately 10" x 4"), Still having mild pain in collar bone area.

Day 1: Mild soreness at injection site, no symptoms otherwise for the next ~30 hours Day 2: At approximately 30 hours after injection: body aches, headache, chills, low fever, swollen lymph node under left arm pit which was the injection site. Day 3: Same as day 2, symptoms began to fade by evening except for swollen lymph node which was worse than day 2 Day 4-6 (today): Swollen lymph node continues, but is mostly subsided from peak swelling NOTES: This was my first injection I had covid starting Dec 27th. Mostly recovered after day 6 except for a lingering cough that lasted for over a month.

Instant funny taste in mouth. tongue swelling, lymph nodes under chin swollen, top of mouth mucousy. Swelling up to eyes. dizzy. dissipated within an hour. Still has swollen arm at injection site. Hard, feels like a golf ball. Headache.

tinnitus, potential hearing loss, severe rash, severe right hip pain debilitating movement, lump at injection site, lymphadenopathy

Both Moderna doses caused flare of gout. Reaction to second dose was worse. Joint pain, swelling, and redness. Treated with anti-inflammatories.

Sudden onset of extreme swelling, itching, heat & painful to touch of the left elbow & forearm, not the original shot location. After initial symptoms the swelling & pain got worse over next 36 hrs

At 5:00 pm yesterday he noticed his right arm was starting to develop some redness and swelling, now feels like a burning/cold sensation at the elbow and upper arm, feels like poor circulation and swollen fingers. Seen by MD who noted right upper extremity mildly erythematous and medial upper arm with no tenderness, r/o phlebitis of right upper extremity.

Fever up to 101.9 lasting 12hrs Joint pain: Hands, elbows, shoulders, neck Swollen Lymph nodes under left armpit Injection Site pain Headache

Per call with hospital infection control nurse, client reported lower extremity weakness at hospital 4/16/21 and was advised to follow up with family physician. Client admitted to hospital 4/18/21 with severe lower extremity weakness. Weakness progressed to upper extremities. Diagnosis of guillain-barre was made. No mechanical ventilation required. Client to be discharged to rehabilitation center.

TWO DAYS FOLLOWING THE INJECTION IN THE LEFT ARM, PATIENT STARTED TO EXPERIENCE LEFT HAND SWELLING AND STIFFNESS. HAS WEAKNESS INTO THE HAND, DROPS OBJECTS. THE HAND IS VERY PAINFUL ALSO. NO FEVERS OR CHILLS. NO OTHER JOINT OR MUSCLE PAINS. NO RASHED. HAS SOME NUMBNESS, NO TINGLING INTO THE HAND. NO TREATMENTS TRIED. NO CHANGE WITH POSITION. NO SIGNIFICANT CHANGE OVER TIME FROM WHEN THE SYMPTOMS FIRST STARTED TO PRESENT DAY TODAY 05/21/2021.

54 days after the first vaccination with Moderna Covid-19 Vaccine, and 25 days after the second vaccination, at approximately 0730 on Day 1, a 52 year old male, height 175.2cm, weight 95.5kg, without significant medical history or prodrome, had an acute onset of dyspnea manifesting as a small sigh at intervals of 4-6 minutes, which increased in frequency to intervals of 2-3 minutes over the course of the day. At approximately 1400 he had a one minute episode of tachycardia >120 bpm. At 1515, his forehead became diaphoretic. He had neither chest pain nor a pericardial friction rub at any time. He went directly to the local emergency department. Additional information for Item 18: Blood pressure at admission was 155/87, pulse 97, respiratory rate 22/minute, SpO2 98%, and Temperature 37.2. ECG at 1539 interpreted as: "NSR at 85, Lateral ST depressions; ST elevations in aVR, ischemia / Posterior wall MI". ECG at 1541 showed: NSR at 82, unchanged from prior ECG. ECG at 1552 interpreted as: "Sinus tachycardia at 102, ST depressions remain in lateral leads but now also in V3 and V4; persistent ST elevations in aVR CW evolving posterior wall MI". PR depression in leads II and V4-6, and reciprocal PR segment elevation in aVR (pericarditis ECG Stage 1) Atypically for pericarditis, ST depression, rather than ST elevation, was present in leads V3-V6. Owing to a working diagnosis of an evolving posterior wall myocardial infarction, an emergent cardiac catheterization was performed, which demonstrated non-obstructive CAD and a small myocardial bridge. Initial laboratory values were notable for a white blood cell count of 11.89 K/mm3 (4.5 - 11.5), monocytes 1.1 K/mm3 (0.0 -1.0), 9.4% (2.0 - 9.0), neutrophils 7.9 K/mm3 (1.5 - 6.6), 66.9% (40.0 - 75.0). Troponin was negative at admission and 18 hours later. D-Dimer was negative. Viral panels including SARS-CoV-2, Influenza A, Influenza B, and RSV were negative. He was admitted for overnight observation. On Day 2 an echocardiogram was normal with no effusion, and ECG was notable for the absence of PR depression and persistent ST depression in leads (PR segment normalization part of pericarditis ECG Stage 2)…... His dyspnea persisted, with a moderate sigh every 1-2 minutes at rest. He was discharged with a presumptive diagnosis of coronary vasospasm or a pulmonary etiology, and told to follow up with his pmd. Over the next several days, his dyspnea was continuous and progressively worsened, and he had diaphoresis of the forehead every morning approximately 0900 until Day 20. Sleep remained normal. On Day 5 he was sighing deeply more than once per minute at rest, causing him distress, and ECG showed (?persistent ST depression in V4-6 with reciprocal changes in aVR). On Day 12, ECG showed T-wave inversion in V1-6 and ST depression in V3-6 (ECG Stage 3); a computed tomography of the chest was normal; and blood tests notable for normal monocyte count .57 K/microliter (0.0 - 0.8), normal CRP 2.15 (1.0-3.0), and an ANA titer of 1:80 (elevated) described as a speckled pattern, which is associated with several autoimmune diseases. Repeat echocardiography on Day 26 showed a small, generalized pericardial effusion and was otherwise normal. Cardiac MRI on Day 29 showed delayed gadolinium uptake. Pulmonary function tests on Day 38 were normal. Stress echocardiography on Day 44 was normal. Cardiac CT angiogram on Day 46was normal. The patient was diagnosed with pericarditis of unknown origin and started on aspirin 650 mg p.o. b.i.d. An ECG on Day 80 showed PR depression in II and V4-6, continued ST depression in II and V3-6, without T wave inversion (T wave normalization c/w ECG Stage 4). Symptoms progressively worsened from onset to nadir around Day 12, on which he had continuous moderate dyspnea upon awakening with severe dyspnea with mild exertion. Symptoms then generally improved until after Day 47, he began to have alternating periods of several days without symptoms followed by several days of mild dyspnea. Clinical symptoms resolved on Day 85.

Adverse immune system response. Redness and swelling under arms for more than a month and has not ceased

Patient only had adverse events after the second dose of covid shot on 05/28/2021. Patient starting getting fever, headache, body aches and lethargy from 5/29-6/2. He woke up this morning (6/3) with cold sores on his lip and he broke out in hives from head to toe. Patient does not come a primary care doctor. Recommended patient to be seen at an urgent care.

a 52 y.o. male sent for evaluation due to symptoms which have now lasted for months and began occurring shortly after he received his second Materna vaccine. He had his first Madrona vaccine on 3/26/2021, and his second vaccine on 4/23/2021. Initially he noted headaches, neuralgia, chills and sweats, and just suspected these would dissipate as had been described in the media. His headaches and neuralgia did resolve, but he continued to have significant night sweats and fatigue. He had one episode where he passed out and struck his head. This has not recurred for over a month. He has had 2 episodes of vomiting bilious material these were significantly spread out. He has noted a 20 pound weight loss and difficulty sleeping. He does report that in the last few days his symptoms seem to have improved, and his appetite has improved as well, but he has not noticed any weight gain yet. He did have low-grade fevers the highest being in the 101 range. He had no visual, taste, pulmonary, genitourinary, rheumatological, or dermatological complaints. Apart from the 2 episodes of vomiting he has had no GI issues. His wife is present and concurs with his history. He has had a significant work-up from his primary care provider who included an LDH in late May that was normal, CBC with differential which was benign, a Monospot which was negative, CRP that was elevated at 85 with 0-10 being the reference range, a negative ANA, negative RA, and a sedimentation rate of 42, blood cultures were performed and were negative. Labs earlier in the month noted similar findings. His basic metabolic panel and liver enzymes were also normal. He was also reportedly screened for Lyme and was negative but I do not see this test result. He denies any childhood infections of significance. The also went to a safari in 2019. They traveled recently prior to the onset of his symptoms but he reports no known bites or scratches by ticks, insects, mosquitoes, or other animals. No one else in the household has been sick. He did receive the BCG vaccine as a child. They also report a chest x-ray was performed and was benign. He was given a 10-day course of amoxicillin and reports no significant improvement while on this.

06/01/2021 PATIENT EXPERIENCED LEG PAIN AND SWELLING, ON 06/05/2021 PATEINT WENT TO THE ER WITH SEVERE LEG PAIN AND WAS ADMITTED TO THE HOSPITAL WITH A DVT. ON 06/07/2021 PATIENT WAS RELEASED FROM THE HOSPITAL AFTER A VASCULAR DOCTOR REMOVED A SUBSTANTIAL CLOT. PATIENT IS CURRENTLY TAKING XARELTO.

Cellulitis in parotid gland; Jawline was swelling quite large; Swollen throat; Difficulty swallowing; Damage from surgery where my lip wont move in one part; Missing two teeth; Infection in my face; earache; Sore throat; Headache; Chills; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of CELLULITIS (Cellulitis in parotid gland), SWELLING FACE (Jawline was swelling quite large) and INFECTION (Infection in my face) in a 52-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. No Medical History information was reported. On 09-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 09-Mar-2021, the patient experienced CELLULITIS (Cellulitis in parotid gland) (seriousness criteria hospitalization and medically significant). On 10-Mar-2021, the patient experienced EAR PAIN (earache), OROPHARYNGEAL PAIN (Sore throat), HEADACHE (Headache) and CHILLS (Chills). On 12-Mar-2021, the patient experienced INFECTION (Infection in my face) (seriousness criterion hospitalization). On an unknown date, the patient experienced SWELLING FACE (Jawline was swelling quite large) (seriousness criterion hospitalization), PHARYNGEAL SWELLING (Swollen throat), DYSPHAGIA (Difficulty swallowing), LIP DISORDER (Damage from surgery where my lip wont move in one part) and TOOTH LOSS (Missing two teeth). The patient was hospitalized from 13-Mar-2021 to 20-Mar-2021 due to CELLULITIS. On 20-Mar-2021, CELLULITIS (Cellulitis in parotid gland) had resolved with sequelae. At the time of the report, SWELLING FACE (Jawline was swelling quite large), INFECTION (Infection in my face), PHARYNGEAL SWELLING (Swollen throat), EAR PAIN (earache), OROPHARYNGEAL PAIN (Sore throat), DYSPHAGIA (Difficulty swallowing), LIP DISORDER (Damage from surgery where my lip wont move in one part), TOOTH LOSS (Missing two teeth), HEADACHE (Headache) and CHILLS (Chills) outcome was unknown. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. Concomitant medications were not reported. On 11-Mar-2021, the patient consulted the doctor because his sore throat and earache on the side of the injection site was painful. He was sent to the emergency room on 12-Mar-2021, for infection in the face. The doctor told the patient that the swelling and pain was from the vaccine and prescribed Motrin. The patient reported that he was getting worse and developed jawline swelling, He went to the hospital on an unspecified date. He was advised admission as he had severe infection and was prescribed antibiotics. On an unspecified date, surgery was done to drain the infection. Drainage was minimal. The patient had surgery a second time, to drain the swelling. He was admitted for a week in the hospital. The patient reported damage from the surgery which included loss of movement of lip in one part and loss of two teeth. For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments. Company Comment Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.MR review complete. Most recent FOLLOW-UP information incorporated above includes: On 21-Jun-2021: Follow-up information received on 21-Jun-2021: Case was upgraded to serious, patient details were updated, additional events were added, hospitalization details and treatment details were updated.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.MR review complete.

DVT - Cramp and Pain in right calf approximately 2 weeks after the 2nd dose of Moderna. Leg Swelling and rash 27 days after 2nd dose with diagnosed blood clot in right leg.

Patient is a 53 year old male who presented to Medical Center Emergency Department on 5/12/2021 with the chief complaint of fever. He is not under the care of a primary care provider and does not take any regular medications. On May 4th patient received his second Moderna COVID vaccine. Several hours later he developed a subjective fever with chills, body aches and a headache. These symptoms have been ongoing since onset. Since this time he has also developed a dry cough, generalized weakness and burning with urination. Denies any shortness of breath, chest pain, nausea, vomiting, or diarrhea. No bloody/dark stools. Wife is at the bedside who states that patient has recently developed "little red bumps" all over his body.

Adverse event: approximately one week after receiving the second Moderna dose (02/02/2021) hives were observed mostly on the chest, waist, back and thighs; also experienced occasional welts on stomach and arms. Noticed swelling appear in face, lips, eyes and cheeks. Denied experiencing trouble breathing and any other symptoms of a severe allergic reaction. Treatment: Seen by a doctor, was first prescribed "Pepcid," took it for about 1 week and saw the hives improve. After noticing a reappearance of episodes of hives and swelling occur, was given "bentimodine" that helped subdue symptoms. Now is on a prescribed regimen of Montelukast 10mg at night, famotidine 20mg BID, zyrtec BID. (continue on lower page)

2 days after injection , the injection site become painfull and resilve un 48 hours, but on 1/2/2021 started to get swollen redness and very hard and firm , also the ventral aspect of the arm felt swollen

Pain in right shoulder joint, pan In right hip joint,. Pain in lower pelvic area and leftlower leg swelling. Difficulty keeping balance at times. loss of strength to right shoulder and right hip

Moderna COVID?19 Vaccine EUA Dr. received Covid-19 vaccine on January 11, 2021 in his office. Dr. reported complaints of abdominal discomfort to his staff starting on January 13 or 14th. Pain and condition worsened. By January 19th, running fever 103.9 F, oral. Labs showed elevated white count. On January 20th, follow up labs and KUB done. Elevated white count and Appendicits diagnosed. Also on January 20th, emergency consult done and emergency surgery done to remove appendix. Reports of Appendicitis noted on follow-up research. Even though reports stated unknow correlations between Covid-19 vaccine and Appendicitis, VAERS report done as precaution.

A couple days after the vaccination I began to have redness, pain, swelling , and itchiness in toes on both feet. It is uncomfortable to wear shoes due to the tenderness and pain in my toes.

Right side upper face and lip mild angioedema. Lasted about 3-4 hours and resolved. Then a week later again in the early morning mild upper face and LEFT lip milder angioedema lasted 2-3 hours and resolved. Now today 4 days after second dose. Very mild angioedema of lower central lip starting early in the morning and lasting only a couple of hours.

pt stated that the night after the vax the left side of his face started drooping, he had severe headache behind left ear and some slurred speech. The next day his symptoms got worse so he took Benadryl since he thought he was having an allergic reaction but he continued to get worse. The third day his speech was getting worse, his face continued to swell and droop and he still had severe headache on the left side. Pt ended up going to the ER where they did a CT, EKG, Chest X-Ray, blood work, gave him IV fluids and steroids. The ER Dr. consulted a Neurologist which told him he had the symptoms of Bell Palsy so they did the stroke protocol but ended up telling him his symptoms were from taking the Covid Vaccine. He was told to finish his medicine that they prescribed which is steroid and antibiotic and if he did not get any better to come back for FU.

12 hours after injection, mild body aches and chills 24 hours after injection, rash on left arm, chest, back and neck; swollen lymph node in neck about the size of a grape, left side near clavicle, possible swelling in lymph nodes in arms pits. Rash felt warm, like a mild sunburn 36 hours after injection, rash disappeared. Lymph node in neck seems smaller.

Feb 12 left arm spelled up and was red and hot Feb 14 Low grade fever that woke me up at 2am Feb 14-15 fever persists off and on all day and sleep escapes me Feb 15 Diarrhea starts around 930 am and persists till 1230pm Feb 14-16 general aches and pains with fatigue

Bump under right armpit felt/noticed on 01/16/2021. It has almost disappeared. My psoriasis on arms/legs apparently temporarily cleared up. It apparently may unfortunately be returning. My white blood cell count had apparently gotten back to normal levels after the 1st vaccine injection on 01/16/2021.

over the course of the week following the vaccination, tiredness, swelling of hands/fingers/wrist/palms that moved to mouth/throat/eyes, itchiness, soreness

The 2nd day after the shot the Lymphnode on the left side of my neck began to swell. 5 days later it was the size of a baseball and was sensitive to the touch. Currently it is about the size of a golfball.

Progressive weakness and paresthesias in BLE and BUE over 3 weeks. Workup suggests guillain-barre syndrome.

A rash appeared around the injection site on my left upper arm and at my bicep, and the lymph node under my left armpit became sensitive. The rash was pink, slightly inflamed, and was slightly feverish. I had mild itching associated with the rash. The rash lasted approximately 48 hours. I would categorize the symptoms as mild. The fact that they appeared 6 days after the vaccination was administered was interesting to me.

Patient report to have been in A-fib for three days after receiving first dose of vaccine; Throat closure; Felt like anaphylaxis; A spontaneous report was received from a consumer who was a 53-year-old, male patient who received Moderna's COVID-19 Vaccine (mRNA-1273) and who developed atrial fibrillation and an anaphylactic reaction. The patient's medical history included heart failure and allergies to butter and NSAIDS. Products known to have been used by the patient, within two weeks prior to the event, included metoprolol, diltiazem, apixaban, lisinopril and loratadine. The patient received their first of two planned doses of mRNA-1273 (Batch number: 040A21A) on 11 Mar 2021 in the left arm for prophylaxis of COVID-19 infection. On 11 Mar 2021, the patient reported that he experienced a moderate reaction; throat closure (not complete). He stated that it felt like anaphylaxis. He also reported having a numb tongue. He reported that the reaction was not immediate and that it started about four hours after the vaccine. Treatment information was not provided. Action taken with mRNA-1273 in response to the events was not provided. The outcome of the event, atrial fibrillation, was considered recovered/resolved. The outcome of the event, anaphylactic reaction, was considered recovering/resolving.; Reporter's Comments: This case concerns a 53-year-old male who experienced a serious anaphylactic reaction with serious unexpected event of atrial fibrillation and throat closure. Event onset occurred the same day as the first dose of mRNA-1273. Treatment not reported. Atrial fibrillation resolved, and anaphylaxis resolving. Based on current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.

I began to breakout in hives on several soft tissue areas of my body and had angioedema in my lips approximately 36 hours post injection.

***16:40 Patient reported red rash and swelling on both arms, mildly itchy. L<R. Extends below shot injection site to finger tips. This occurred about 15 minutes after receiving the Moderna vaccine BP 155/81, Pulse 80. SpO2 98% . Denies respiratory difficulty. No trouble swallowing 16:55 Increased itching under left arm as well as mild itchy on torso. Red rash continues to be evident on arms. Arm swelling. "Feeling sleepy". Respirations easy and unlabored. BP 140/105, pulse 82. SpO2 96%. Alert and oriented. Continued to monitor while EMS contacted. Ambulance responded, transporting patient to ED at 1710.

shoulder pain; could not turn his neck for about 3 weeks; Fingers are really bad; fingers bent down at night and he had to pull them and straighten them up; Could not walk because his toes and fingers hurt; All his blood work for the rheumatoid markers were elevated; Severe neck pain; it aggravated his Rheumatoid Arthritis; sweats; low grade fever; A spontaneous report was received from a consumer concerning a- 53 Years old, Male patient who experienced aggravated Rheumatoid Arthritis. The patient's medical history included that he has had Rheumatoid Arthritis for a couple of years Products known to have been used by the patient, within two weeks prior to the event, included Prednisone and Leflunomide On 15 Jan 202, the patient received their first of two planned doses of mRNA-1273 (Batch number: [0126ZOA]) On 12 Feb 2021, the patient received their second of two planned doses of mRNA-1273 (Batch number: [013L20A]) for prophylaxis of COVID-19 infection. On 12 FEB 2021, the patient experienced low grade fever and sweats. On an unknown date, the patient experienced flare up of his Rheumatoid Arthritis with shoulder pain, severe neck pain and was unable to turn his neck for about 3 weeks, fingers were really bad, bent down at night and he had to pull to straighten them up and was not walk because his toes and fingers were hurting. Blood work for the rheumatoid markers were elevated. Treatment included prednisone and leflunomide. Action taken with the drug in response to the event(s) is not applicable. The outcome of the events, low grade fever, sweats were Recovered/Resolved. The outcome of the other events were were not known.; Reporter's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

After about 4 hours after the vaccine was administered, patient's arm swelled up and was swelling and hurting until 2-3 AM that night. Patient woke up and had hives all over body and was itchy. Body turned red and had small bumps. Patient took benadryl and symptoms cleared up. Hives would come back periodically and patient would take more benadryl every 6 to 8 hours. Patient went to his Dr's office and they prescribed him cetirizine with hydroxyzine. Symptoms resolved after a couple of hours.

History of Present Illness: This is a 53-year-old male with significant past medical history of cerebral palsy, mental retardation, decubitus ulcer, recent left loculated pleural effusion with empyema status post catheterization line placement by IR at outside hospital. Patient is A&O times 2-3 at baseline. This patient presents with recent fall associated with right shoulder pain, decreased range of movement and minor bruise to forehead. Per report from nursing home patient was also altered and slightly confused. Due to concern for intracranial process patient was transferred to the ED for further workup. In the ED, vitals were remarkable for mild tachycardia. Patient was noted to be hypoxic on room air an Additional information for Item 18: Patient was noted to be hypoxic on room air and placed on 3 L oxygen via nasal cannula. Initial labs show leukocytosis 28.6. For concern for sepsis blood cultures obtained patient initiated on antibiotics vanc and Zosyn. Status post 2 L IV fluid bolus. Inflammatory markers elevated patient tested for COVID-19 infection. CT brain negative for fracture. CT abdomen showed nonspecific thickening of the colonic wall may represent colitis in appropriate clinical setting.

staph infection around the same time as getting the vaccine; Skin Sores looking like Chickenpox (Majority on Torso and groin area); Painful and Swollen Lymph Nodes (Groin and Arm pit ); Malaise; Sore left shoulder; This spontaneous case was reported by a consumer and describes the occurrence of STAPHYLOCOCCAL INFECTION (staph infection around the same time as getting the vaccine) in a 53-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 045A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. The patient's past medical history included No adverse event (No medical history reported). On 20-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 20-Mar-2021, the patient experienced MALAISE (Malaise) and ARTHRALGIA (Sore left shoulder). On 26-Mar-2021, the patient experienced SKIN LESION (Skin Sores looking like Chickenpox (Majority on Torso and groin area)) and LYMPHADENOPATHY (Painful and Swollen Lymph Nodes (Groin and Arm pit )). On an unknown date, the patient experienced STAPHYLOCOCCAL INFECTION (staph infection around the same time as getting the vaccine) (seriousness criterion medically significant). On 23-Mar-2021, MALAISE (Malaise) and ARTHRALGIA (Sore left shoulder) had resolved. At the time of the report, STAPHYLOCOCCAL INFECTION (staph infection around the same time as getting the vaccine) outcome was unknown and SKIN LESION (Skin Sores looking like Chickenpox (Majority on Torso and groin area)) and LYMPHADENOPATHY (Painful and Swollen Lymph Nodes (Groin and Arm pit )) was resolving. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. No treatment information was provided. No concomitant medication was provided. Most recent FOLLOW-UP information incorporated above includes: On 30-Mar-2021: New adverse event; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

Felt weak for 1 and half days after the following day of vaccination. Arm was sore and red swelling for a week and gone now but this area still itches even after a week, I don't know when this will go away.

Almost 2 weeks after the shot, I have a lump under my left armpit. Shot in my left arm was 8/27 and lump appeared 4/8.

Treated for a tick bite with doxycycline on 3/26/2021 diagnosis of anaplasmosis. Developed Progressive focal motor weakness Reflex abnormality Leukocytosis, unspecified type Leg pain, bilateral Bell's palsy

Moderna 1st shot, left arm. Left arm pit swelled lymph node with soreness. It?s been 3 days, it is getting better.

Left armpit lymph node sore, soreness in left rib cage, and swelling on left side all the way down to hip.

Enlarged lymph node in left armpit, baseball size. Painful/bruised, appeared less than 24 hours after second injection of Moderna #2.

Acute itchy rash with raised welts starting on forearms and gradually moving to upper arm, chest, stomach and legs. Dr. prescribed Prednisone and Claritin during the day and Benadryl in the evenings. Took it for a week with no improvements. Today the Dr. prescribed Zyrtec and Pepcid

"Moderna Covid 19 vaccine Eua" Swelling in feet and legs. Turned serious very quickly went to ER skin was so tight that cracking occurred with sores. Intravenous antibiotic and oral antibiotics given for treatment

Moderna COVID-19 Vaccine EUA Around five days after receiving my first shot I started feeling aching and throbbing on my left side in my neck, shoulder blade, shoulder, bicep area down to my elbow, and a swollen lymph node in my left arm pit. My neck, bicep area, and shoulder is still producing a throbbing type pain. On April 18, 2021 I awoke to the tip of my left thumb being numb. It is still numb as of today, April 23, 2021..

patient reported facial swelling and L sided droop starting after the 2nd Moderna vaccine he received on Friday 4/23. Noted initially a headache, not localized to any area, and about 8-10 hours after noticed facial swelling bilaterally on eyes, lips, and down to his throat. His L side of the face was also noted to be drooping, the next day, including inability to raise his eyebrow on L, difficulty closing L eye, and a L sided mouth droop. Reports the swelling started to get better just prior to arrival in ED, however is still persistent and includes the lips and throat, says it feels like the inside is swollen. Was able to tolerate liquids but noted some difficulty. Denies any difficulty breathing. Also denies any extremity weakness, vision changes, balance issues, speech deficits other than what's related to lip swelling and mouth droop

Systemic: Allergic: Itch (specify: facial area, extremeties)-Mild, Additional Details: pt reported mild swelling and itching feeling of left hand only. evaluated by pharmd immunizer; no significant swelling noted by this writer when comparing L vs R hand. provided diphenhydramine 25mg po x 1 for itching per pt request (pt was not driving home). w/in 10 min of taking dose, pt stated he felt much better.

Patient received Moderna shot, during observation period he reported burning in the throat, metallic taste and left lower arm swelling and red. Blood pressure at 10:00 am 136/82, pulse 76, SaO2 97% on room air. Respirations normal, cardiac eval normal, throat normal, tongue normal, lips normal. No rash, swelling, redness or bruising noted at site of the injection. Denies any other symptoms. Diphen 25 mg given, after 20 minutes patient reports improvement of throat symptoms and decreased redness of left lower arm. second dose of Diphen 25 mg given and after 20 minutes patient reports metalic taste resolved, burning in throat resolved, redness of arm resolved. Only remaining symptom was mild hand swelling. Follow up blood pressure at 10:14 am 126/82. Follow up exam, no swelling or erythema of lips, tongue, throat. no shortness of breath, wheezing or difficulty breathing. Discharged ambulating.

patient came back to pharmacy today as his md advised him to report to us rash on upper left chest, swollen lymph nodes on left under arm, and lower right side stiffness

Bad sinus infection that took three rounds of antibiotics to clear. Swollen lymph nodes under both armpits.

24 hours after 2nd dose had 103 fever, swollen lymph node, lethargy for 48 hours. almost 3 months subsequent to 2nd dose, developed Bell's Palsey on left side of face (5/18/21)

Patient presented to the ED and was subsequently hospitalized within 6 weeks of receiving COVID vaccination. Diagnosis was severe sepsis.

Patient came in for swelling and pain to left calf, he also had a nodule to the medial posterior aspect of the calf. He reported the symptoms were since approx the 5/17/21. Pt said it possibly started sooner on the 15th. Pt came in today 5/21/21 because he received an ultrasound at a clinic by referral from his pmd and was dx with a DVT to the left calf. His pmd then referred him to come to ER where I triaged him in the triage department. He mentioned that began feeling bad after the Moderna Shot he received on 4/28/2020 and stated the now he has this new problem that he never had in the past. Only hx was mild htn he said.

The first 14 hours I had fevers with up to 102.9, rigors, fatigue, headache these symptoms lasted over 6 days. Significant swelling of tongue where I couldn't close my mouth. I also had a sore throat with pustules that were treated with antibiotics as well as swollen glands in my throat. Very similar to my symptoms from when I had COVID back in March 2020. I was prescribed antibiotics for the swollen tongue and pustules.

Patient manifested with flu-like symptoms (myalgias, fatigue, cough, abdominal discomfort, shortness of breath) with high-grade fevers (TMax 103F) approximately 4-6 hours following administration of 2nd Moderna vaccine on 5/4/2021 per patient's wife. The symptoms progressively worsened to the point that he presented to an outside hospital on 5/12/2021 at which time he was found to be tachycardic and febrile (T 103.1F). Labs at that time were notable for significant thrombocytopenia, elevated creatinine, elevated lactate, elevated procalcitonin. Chest imaging showed bilateral airspace disease. CT of the abdomen noted hepatosplenomegaly with no evidence of lymphadenopathy. Echocardiogram showed normal cardiac function. He was empirically started on broad-spectrum antibiotics. Labs on 5/13/2021 were notable for a markedly elevated ferritin level, fasting hypertriglyceridemia, elevated CRP, elevated transaminase levels, hyperbilirubinemia, markedly elevated CXCL-9 level, markedly elevated IL-18 level, normal natural killer cell function. Of note, while his blood and urine cultures were negative, he was found to have elevated EBV viral load on peripheral blood draw. He had a bone marrow biopsy which reportedly showed rare evidence of cells with what appeared to be erythrocytes within their cytoplasm, concerning for HLH. Given strong clinical and serological suspicion for HLH, he was transferred to our hospital for a higher level of care. Upon transfer to our facility on 5/18/2021, his inflammatory markers were persistently elevated. He unfortunately developed worsened renal and respiratory failure, and required both hemodialysis and intubation respectively. He was continued on empiric broad-spectrum antibiotics, however we additionally initiated high-dose steroids as well as anakinra for treatment of HLH. Given EBV viremia, we also began rituximab therapy. He was successfully extubated, however as of 5/26/2021 remains dialysis-dependent with continued improvement in urinary output. His post-intubation course has been complicated by encephalopathy of unknown etiology. We have consulted infectious disease to proceed with a diagnostic lumbar puncture to ascertain potential CNS pathogens explaining the cause of his altered mental status. MRI of the brain showed no evidence of pathology. CNS involvement by HLH remains on our differential.

Patient reported signs and symptoms of SOB/right leg pain 1 week after receiving the Moderna vaccine. He stated that he was "breathing fire" and woke up with an extremely painful and swollen leg. Upon coming to the ED, it was found to be bilateral PE and right leg DVT.

They diagnosed him with delayed (about 18 Hours) anaphylactic reaction due to the vaccine; His lungs were filled with fluid; After 2nd dose, next day morning at 9AM, he didn't feel well while at work; He had upset stomach; He started feeling light headed while driving/very light headed; When he walked in the house, he was short of breath; Turned gray/about a minute and half later, he turned purple and blue; His oxygen was dropped to low 70s; His BP dropped to 80/50; His entire torso was covered in a rash; Very nauseous; On the way home, he started vomiting; He felt little achy; This spontaneous case was reported by a consumer (subsequently medically confirmed) and describes the occurrence of ANAPHYLACTIC REACTION (They diagnosed him with delayed (about 18 Hours) anaphylactic reaction due to the vaccine) and PULMONARY OEDEMA (His lungs were filled with fluid) in a 53-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 043B21A and 007B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. No Medical History information was reported. On 14-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 12-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 13-May-2021, the patient experienced ANAPHYLACTIC REACTION (They diagnosed him with delayed (about 18 Hours) anaphylactic reaction due to the vaccine) (seriousness criteria hospitalization and medically significant), PULMONARY OEDEMA (His lungs were filled with fluid) (seriousness criteria hospitalization and medically significant), VACCINATION COMPLICATION (After 2nd dose, next day morning at 9AM, he didn't feel well while at work), ABDOMINAL DISCOMFORT (He had upset stomach), DIZZINESS (He started feeling light headed while driving/very light headed), DYSPNOEA (When he walked in the house, he was short of breath), SKIN DISCOLOURATION (Turned gray/about a minute and half later, he turned purple and blue), OXYGEN SATURATION DECREASED (His oxygen was dropped to low 70s), BLOOD PRESSURE DECREASED (His BP dropped to 80/50), RASH (His entire torso was covered in a rash), NAUSEA (Very nauseous), VOMITING (On the way home, he started vomiting) and MYALGIA (He felt little achy). The patient was hospitalized from 13-May-2021 to 14-May-2021 due to ANAPHYLACTIC REACTION and PULMONARY OEDEMA. At the time of the report, ANAPHYLACTIC REACTION (They diagnosed him with delayed (about 18 Hours) anaphylactic reaction due to the vaccine), PULMONARY OEDEMA (His lungs were filled with fluid), VACCINATION COMPLICATION (After 2nd dose, next day morning at 9AM, he didn't feel well while at work), ABDOMINAL DISCOMFORT (He had upset stomach), DIZZINESS (He started feeling light headed while driving/very light headed), DYSPNOEA (When he walked in the house, he was short of breath), SKIN DISCOLOURATION (Turned gray/about a minute and half later, he turned purple and blue), OXYGEN SATURATION DECREASED (His oxygen was dropped to low 70s), BLOOD PRESSURE DECREASED (His BP dropped to 80/50), RASH (His entire torso was covered in a rash), NAUSEA (Very nauseous), VOMITING (On the way home, he started vomiting) and MYALGIA (He felt little achy) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 13-May-2021, Blood pressure measurement: 80/50 (Low) 80/50. On 13-May-2021, Oxygen saturation: low 70s (Low) low 70s. Patient's concomitant medication included nasal spray. He was admitted to the hospital. They diagnosed him with delayed (about 18 Hours) anaphylactic reaction due to the vaccine. The patient was discharged from the hospital on 14-May-2021 evening. The patient was treated with Epi-pen and steroids. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

Dermatitis bullous; Erythema; Peripheral swelling; Pruritus; Somnolence; Hypertension; This case was received via FDA VAERS on 01-Jun-2021 and was forwarded to Moderna on 01-Jun-2021. This regulatory authority case was reported by an other health care professional and describes the occurrence of DERMATITIS BULLOUS (Dermatitis bullous) in a 53-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 018B21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. No Medical History information was reported. On 29-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 29-Mar-2021, the patient experienced DERMATITIS BULLOUS (Dermatitis bullous) (seriousness criterion medically significant), ERYTHEMA (Erythema), PERIPHERAL SWELLING (Peripheral swelling), PRURITUS (Pruritus), SOMNOLENCE (Somnolence) and HYPERTENSION (Hypertension). At the time of the report, DERMATITIS BULLOUS (Dermatitis bullous), ERYTHEMA (Erythema), PERIPHERAL SWELLING (Peripheral swelling), PRURITUS (Pruritus), SOMNOLENCE (Somnolence) and HYPERTENSION (Hypertension) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 29-Mar-2021, Blood pressure measurement (120-80): 140/105 (High) BP 140/105mmHg and 155/81 (High) 155/81mmHg. On 29-Mar-2021, Heart rate: 80 (normal) 80 bpm and 82 (normal) pulse 82 bpm. On 29-Mar-2021, Oxygen saturation: 98 % (normal) SpO2 98% and 96 % (normal) SpO2 96%. The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown. For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments. The patient had red rash and swelling on both arms, mildly itchy. Extended below shot injection site to finger tips. Increased itching under left arm as well as mild itchy on torso. Alert and oriented. No concomitant medication information was provided. No treatment medication information was provided. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded. Reporter did not allow further contact; Sender's Comments: Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.

Patient complained of burning, hot feeling running up his arm about 10 mins after receiving the IM vaccine. Also complained of "plastic" smelling and taste in his mouth at the same time. Patient then complained left arm and hand were more swollen than right arm. (Difficult to tell because patient was "heavy set with large thick arms"). He stated no difficulty breathing. Offered him Benadryl 25mg and water, which he accepted. After 30 mins he said he felt better.

Seizures; Bood clots; Stuggling to breathe; Struggling to walk; ARDS; Acute hypoxic respiratory failure; Acute exacerbation of heart failure and sepsis; Acute exacerbation of heart failure and sepsis; Cardiac arrest; Blood infection; Fever; This spontaneous case was reported by a patient family member or friend (subsequently medically confirmed) and describes the occurrence of ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS), ACUTE RESPIRATORY FAILURE (Acute hypoxic respiratory failure), SEPSIS (Acute exacerbation of heart failure and sepsis), CARDIAC FAILURE ACUTE (Acute exacerbation of heart failure and sepsis), CARDIAC ARREST (Cardiac arrest), SEIZURE (Seizures), THROMBOSIS (Bood clots), DYSPNOEA (Stuggling to breathe) and GAIT DISTURBANCE (Struggling to walk) in a 53-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below. Concurrent medical conditions included Obesity. On 16-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 15-May-2021 at 2:00 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 15-May-2021, the patient experienced ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) (seriousness criteria death and medically significant), ACUTE RESPIRATORY FAILURE (Acute hypoxic respiratory failure) (seriousness criteria death and medically significant), DYSPNOEA (Stuggling to breathe) (seriousness criterion hospitalization prolonged) and GAIT DISTURBANCE (Struggling to walk) (seriousness criterion hospitalization prolonged). In May 2021, the patient experienced SEPSIS (Acute exacerbation of heart failure and sepsis) (seriousness criteria death and medically significant), CARDIAC FAILURE ACUTE (Acute exacerbation of heart failure and sepsis) (seriousness criteria death and medically significant), CARDIAC ARREST (Cardiac arrest) (seriousness criteria death and medically significant), INFECTION (Blood infection) and PYREXIA (Fever). On 17-May-2021, the patient experienced SEIZURE (Seizures) (seriousness criteria hospitalization prolonged and medically significant) and THROMBOSIS (Bood clots) (seriousness criteria hospitalization prolonged and medically significant). The patient was hospitalized from 15-May-2021 to 25-May-2021 due to DYSPNOEA, GAIT DISTURBANCE, SEIZURE and THROMBOSIS. The patient died on 25-May-2021. The reported cause of death was Cardiac arrest, Acute hypoxic respiratory failure, ards and acute exacerbation of heart failure and sepsis. It is unknown if an autopsy was performed. At the time of death, SEIZURE (Seizures), THROMBOSIS (Bood clots), DYSPNOEA (Stuggling to breathe), GAIT DISTURBANCE (Struggling to walk), INFECTION (Blood infection) and PYREXIA (Fever) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 15-May-2021, Blood pressure measurement: elevated (High) Twice normal. On 15-May-2021, Glycosylated haemoglobin: elevated (High) High. On 15-May-2021, Oxygen saturation: low (Low) Required intubation and was placed on ventilator.. On 15-May-2021, SARS-CoV-2 antibody test: negative (Negative) 1 negative COVID antibody test. On 15-May-2021, SARS-CoV-2 test: negatie (Negative) 3 negative COVID antigen tests. No concomitant medications were provided. It was reported that within few hours after second dose of vaccine patient was struggling to walk and to breathe. The reporter and her husband went to see the patient and took him to an emergency room (ER). In the ER his blood pressure was markedly elevated (twice normal) and his oxygen level was low and by midnight he required intubation and was placed on a ventilator. His HbgA1c was noted to be elevated. Two days after admission (17-May-2021), he developed seizures which the medical team believed to be due to blood clots and he was anti-coagulated. It was determined that he did not have blood clots on his heart valves as the source of the clots. The source of the blood clots was never identified. He later developed fever and was diagnosed with a blood infection and treated with antibiotics. At one point his oxygen requirement on the ventilator went down to 65% but later returned and remained at 100%. He ultimately died on 25-May-2021 and as per copy of his death certificate he had 4 causes of death as cardiac arrest, acute hypoxic respiratory failure, acute respiratory distress syndrome (ARDS) and acute exacerbation of heart failure and sepsis. Treatment included, anticoagulants, antibiotics, intubation and ventilator. Very limited information regarding these events has been provided at this time. Further information has been requested. This case was linked to MOD-2021-219410 (Patient Link).; Sender's Comments: Very limited information regarding these events has been provided at this time. Further information has been requested.; Reported Cause(s) of Death: Cardiac arrest; Acute hypoxic respiratory failure; ARDS; Acute exacerbation of heart failure and sepsis

Pt reported syncope and collapse on 6.13.21, onset of LEFT leg swelling, chest pain and dizziness 6.17.21. Pt was diagnosed with extensive DVT of LLE and bilateral PE with significant clot burden on 6.22.21

I received my second dose on 4/24/21. On 4/29/21 I had a required annual EKG. The test indicated abnormal (inverted) T waves. This was very uncharacteristic. The abnormal EKG triggered a nuclear stress test and echocardiogram, conducted several weeks later. All normal. I'm fit and active for may age and in otherwise good health. I had an additional issue on the same date as the abnormal EKG. Foot pain and swelling in the right foot, and four weeks later, the left foot. The rheumatologist's diagnosis is gout with appropriate treatment plan, but tests are inconclusive.

Severe pain and swelling in ankles and legs that lasted for more than eight weeks. Lumps appeared under the skin that were extremely painful to touch. Substantial joint pain ankles, knees, elbows, and wrist was present and varied in location and severity.

Patient experienced Gout in his left foot 2 days after takin the vaccine. Patient has never had gout before. The gout was so painful that the patient had to crawl around the house. Patient has seen a DR. Patient says that he now has to watch what he eats. Patient said that foot swells at least once a month.

I had chest pains. My platelets cell was 543 and white blood cells count was 26000. I went in to the ER after 4 days and was diagnosis as having a heart attack. Cholesterol 203 results. triglycerides was 85.

Pt complained of knee and lower leg pain and swelling that has been going on for one month, but gradually lessening

Four days after receiving the vaccine - developed flu like symptoms: headache, temperature, body aches, chills. Following day developed pain and swelling in left armpit. Two days after that a large red welt developed on left deltoid (site of injection).

Day 1 Nausea- 4 hrs after Swollen face/neck- 3 to 5 hrs- benadryl Left eye extreme blurry vision- 3 x's 2 to 5 min each Mental fog and confusion- 3 days intense, 4th day trouble with recall without intense focus Headache- 3 days intense, 4th day- moderate Elevated heartrate- sporadic first day until 6 pm Highly irritable- 2 days Incessant talking and moving

Swelling and numbness in the right cheek/jaw area. Started 1/11/21 around 5pm. The patient notified us on 1/12/21 at 1545. He said that the swelling was "starting to go down, and seems like it is a little better." The patient reports he had a similar reaction to ace inhibitors last year, but on the opposite side of his face. He was advised to seek medical treatment if it gets worse or if he has any issues with breathing. Patient verbalized understanding.

1/16/2021 Pain to injection site upper arm, Slight swelling of Lymph nodes to that arm, Extreme fatigue resulting in sleeing most of the day and nausea without vomiting, loss of appetite. No fever 1/17/2021 pain and nausea subsided, fatigue improved but still not back to 100%

Saturday, 1/09/2021-Foggy, nasuea and tired. took 1-2 hoiur nap and symptoms went away. Thursday, 1/14/2021-Slight rash on right deltoid, around injection site. Applied topical bebdryl and rash went away by Monday, 1/18/2021. Thursday, 1/14/2021-Swelling in right armpit region medial to right pectoral muscle. no fever pain/tenderness around area affected. On Monday, 1/18/2021 swelling remains.

Initially there was soreness at injection site which lasted about a week, lessening with each day. I was incredibly fatigued for about three days after. Also, the entire right forearm felt sore for about a week, as well. The day after vaccine shot, my right testes was achey and sore (and still is uncomfortable) Also, the top side of my right foot was very tender. During the course of the week, that part of my foot became lightly swollen as did the front of my right leg, up to the top of the shin bone. Today?s date: 1/22/21 5:19 pm and leg and foot still tender and slightly swollen.

Following 2nd dose: Left chest swelling approx 7 inches in diameter near left axilla. Lymphadenopathy and tenderness of the left axilla. Back pain, "sand paper" skin with urticaria. Following 1st dose: back ache and urticaria x 2 weeks

Ten minutes after - headache for about 10 hours. About 26th, my back and neck - the joints were sore and I couldn't get out of bed. On 27th - felt better; but my foot (right ball, top of foot and big toe and toe right next to big toe) started swelling up. I went to the Dr. - gave me meds for the swelling (Prednisone)(I don't have a history of gout). It went away and I was fatigued for two weeks. That went away and then got my second dose (on January 19th) my toe swelled up again and they tested it this time and it was URIC acid for gout.

21st - swollen big toe and upper part of foot - I had swelling but not as bad as first dose of vaccine; some of my joints sore, too. On 26th of January, I had shortness of breath and a little dizzy. It was tolerable but was there. Toe/foot symptoms resolved around January 31st but I did still have shortness of breath up until the 2nd of February. Dr put me on Colchesine and Alloepurinal

Dizziness, Headache & Anemia Narrative: Received #1 dose of vaccine 12/28/21, noticed dizziness vertigo headache at the same time period, edema to lower extremities. Received #2 dose 1/20/21, within 4 days noticed headache, continues to have headache to present. Advised to follow up with pmd 2/18/21 as color was pale, Hgb 5.4, admitted and transfused with 2 u prbc.

Patients daughter called to inform us that her fathers arm became very swollen and red the day after vaccine administration. She also stated that although the patient was not in excruciating pain, the patient did express discomfort and a burning sensation on the arm. Patient contacted his doctor and followed prescribers instructions for treatment.

"s/p 2nd Moderna shot 02/24/2021. arm swelling, feverish, ache, w/o erythema. - f/c/ns, - myalgia, -cough/Wz/SOB, -n/v/d, Smell & taste intact, No rash. Eat/sleep well, BM/Urine OK."

At 5 days post vaccination, patient developed severe left shoulder pain, originally thought to be secondary to chronic shoulder pain and a recent fall, over the next three days it progressed to swelling, severe pain, and limited ROM. He ended up being admitted to the hospital and CT scan showed development of significant soft tissue infiltration around sternum and sternoclavicular joints. This was originally thought to be infectious, but he never developed a fever or leukocytosis and we feel this was most likely an inflammatory process. I have no idea if this was actually a vaccine side effect, but given the proximity in both time a location and the known complication of shoulder pain with the vaccine, it seems reasonable to give you the information to monitor for other similar cases.

24 hours after first vaccine administration I developed was has been described as 'Covud Toes.' Several Toes on right and left feet became swollen, red with visible signs of inflammation, and sore. I had a similar response after having an unconfirmed covid infection two months earlier. My symptoms have persisted for two weeks now, and I was advised by my PCP not to get the 2nd injection.

Patient had usual post vaccination myalgias and lethargy for a few days after injection. These resolved spontaneously. However, about a week after vaccination he developed recurrent fevers 102°F. He also had complaints of body aches and bilateral jaw pain. He had extensive evaluation including laboratory testing for infectious etiologies of his fever and none was identified. He was noted to have very high sed rate and CRP. When no specific etiology for his fevers could be identified we decided to proceed with a short course of prednisone which did seem to help his fever and jaw pain. After prednisone was stopped he had recurrence of fever and developed worse jaw pain and pain at the base of his neck. I examined him in clinic and found that he had a tender swollen thyroid. I directed him to the emergency department where CT scanning of his neck confirmed evidence of thyroiditis. TSH was undetectable and free T4 was about 2 times higher than normal. He was diagnosed with subacute thyroiditis. However, his symptomatology seemed quite dramatic for subacute thyroiditis, and the timing in relation to his vaccination is concerning for possible adverse vaccine reaction.

First symptoms to appear were noticeably sore right arm and fatigue about six hours after injection. About eleven hours after shot I had headache, feeling of irregular body temperature, nausea, body aches.. I took Pepto-Bismol for the nausea which helped. About 24 hours after the injection I experienced sore armpit/lymph nodes of shot arm. All but the symptoms except the sore armpit/lymph nodes were mostly gone within 30 hours of the shot. The lymph nodes felt better a day or two later.

After 1st injection (1/11/21) experienced severe shortness of breath with minimal activity with accelerated heart rate and drop in O2 stat. within 2 days of injection then developed wheezing cough. Primary MD prescribed Augmentin nd prednisone with eventual success. With normal blood work, chest x-ray and negative Covid test all done by 1/15. On 3/9/21 (28) days after second dose (2/11/21) experienced burning and swelling on right leg. Went to Hospital, ER and found extensive blood clots in right leg and saddle pulmonary embolism . Also had 50% Platelet blood count decrese since the 1/15 bloodwork Admitted for 3 nights on heparin dip. Discharge on home Lovenox injections for 30days.

patient received dose one of Moderna on 3/16/21. On 3/17/21 the patient began feeling facial pain and a feeling of swelling over the right maxilla and upper lips. He did not notice any lesions. this continued until morning of 3/20/21 when he woke with a right lower facial droop and difficultly closing his right eye. Physical examination was consistent with a Bell's Palsy. No prior history of Bells Palsy in the patient.

Fatigue headache muscle pain nausea and lymph nodes under my right arm and I'm still sore and have headache I can't really hold up my right hand.

54 y ea rold male states he had swelling of left arm and breast and thinks he has a muscle twitch of left pectoralis muscle from vaccine. Has had sx for past four weeks . Mild but he has no other sx.

Injection site reactions: pain, tenderness, and swelling of the lymph notes in the same arm of the injection. General side effects: fatigue, headache, muscle pain, chills, nausea and fever of 101 degrees.

Swelling in both lower legs was first noticed while playing sports the day after the shot was taken. Legs still continue to swell when I am in a prolonged sitting position (+3 hours). Usually, legs become swollen to a point in which I feel the skin is very tight and they become hard. I have been lying with feet up to relieve the pressure. Q: how long will this continue? should I see a doctor? should I take the second Moderna shot? Advice would be appreciated.

Localized muscle soreness and mild skin tenderness. Localized mild edema. Reddish/ tan skin blotch below injection site and wrapping around the bicep but not the skin inside the bicep - gone by Day 4. Mild swelling and soreness of lymph nodes in the axilla of injection arm - gone by Day 4. Mild body aches and malaise which resolved fully within 24 hours.

Patient was given 2nd Moderna vaccine at about 7:30. Patient was pale and diaphoretic and was lowered to the floor by RN and another patient receiving the vaccine who was a cardiologist. He had several beats of clonus and then woke up. He was awake when his first vital signs were obtained. HR 110, BP 190/96, O2 sat 100%. When he was more awake he was assisted in to a reclining chair. BP monitored every few minutes and dropped as low as SBP 104, HR 70-80s. Pt reported that he periodically syncopizes, last 6mo ago. He reported feeling lightheaded after seeing his arm bleed and be swollen after vaccination. After about 1 hours the patient's vital signs were stable but he continued to have symptoms of lightheadedness which worsened when I sat him up (though BP was stable). EMS was called and he was transported to the ED.

Acute pain 2nd and 3rd day after vaccination.After a week red spot in arm, swollen, no pain. I think it will be get better.

Had swelling of that and numbness in lips and stomach started hurting and only took 10 mins after shot.Then the people admitted ephi into my leg..03mg.And then fire department got called and got 50 cc of liqard benadryl into me and iv and it was off to the hospital and got some prednisone and and was in hospital for 8 hrs

4/23/21 Severe headache began within 2 hours of receiving the vaccine. Body ache, chills and low grade fever into the evening and overnight. Sore right arm. 4/24/21 In the morning headache and body ache. Late afternoon severe body ache, chills, 101 degree fever. 800mgs of ibuprofen and 1000mgs of Tylenol every 6-8 hours did not bring the fever down. Sore right arm. 4/25/21 Headache and body ache all day. Late afternoon headache continued but with severe body ache, chills, 100 degree fever, swollen lymph nodes in right arm pit, red, hot and swollen rash between right shoulder and neck, sore arm. We called the emergency department and they stated it could take up to 3 weeks before the painful swollen lymph nodes in the arm pit would dissipate. They left it up to us whether to come in. We chose not to because we didn't feel there was anything more they could do for us.

Patient received Moderna #1 vaccine to left deltoid; the next day he had a grapefruit size swelling to his left axilla. He went to his PCP who obtained an ultrasound which showed lymph node swelling.

I awoke the morning of the 28th feeling slightly fatigued with some soreness at the injection site. By lunchtime, I am experiencing extreme fatigue, overall body soreness, loss of appetite, and increased pain at the injection site. By 3 pm I am home and in bed, dealing with chills/sweats as well. Couldn't find any comfort to sleep thru the night. In the morning of the 29th, I'm still displaying all the issues listed above. I stay home from work and go back to bed. I awake at noon to find all the listed issues greatly reduced, but feel soreness in my jaw and feel swelling in the lymph nodes under the jawbone, more so on the right than the left.

Superficial blood clot in right foot. Symptoms: pain in arch of right foot, red blotch and tender area on top of right food after about 2 days after 2nd shot. Area of pain gradually expanded and traveled up the right leg with some swelling and tender areas.

2 inch x 2 inch Raised red welt with severe itching turned into red hot swollen 6"x5" hot red area- treated with benadryl, cold compress, elevation

Event happened at home, patient was taken to ER where he was treated. Health Dept notified. Upper extremity edema right greater than left, facial edema right greater than left, slight heel edema right greater than left, Tingling sensation in tongue Treatment with IV Benadryl, Dexamethasone, and Pepcid. Discharged with new RX Epi pen, steroids, and Pepcid

Patient comes with bilateral burning thigh pain and weakness for 2 weeks that began 1 week after Moderna COVID vaccine. MRIs of T & L spine are non significant. Inflammatory markers are elevated and he has worsening kidney disease than his baseline. Also with anemia. 4/29 MRI thigh muscles show extensive edema R>L suggestive of myositis from some source. Nephrology considering renal biopsy for his progressive kidney failure. Patient may have autoimmune or inflammatory process affecting both muscle and kidneys. Have sent for autoimmune antibodies as well as other vasculitic markers and requested muscle biopsy by general surgery. He needs to be started on steroids.

5 mins after initial shot, rapid heart rate that subdued in approximately 15 min. About 12 hours after the shot, experienced swelling in face and closure of throat, excessive sweating, fatigue and disorientation/dizziness and muscle paralysis/weakness in the back of neck, needing to use my hand to lift my head up.

Admitted to ER on 4/17 with severe abdominal pains and diagnosed with pancreatitis and pseudocyst. Admitted to ER again with the same symptoms on 5/4. This time diagnosed with continued fluid on the pancreas and possible subsegmental portal vein thrombosis in the liver.

Had pain in my shoulder (and neck on my left side) as soon as the shot went in. At roughly three hours after the shot, I felt I was slurring my speech (I had to make a very concerted effort to make proper sentences and not slur) and was very dizzy. I also was having a hard time with lights. For example, I was unable to look in the mirror in my bathroom as the lights above the mirror were too bright for me. At three hours after the shot, I had severe pain in my left shoulder. Overall, I felt as I had been sedated or drugged. I tried walking to the nearest convenience store to get some food and I felt I was experiencing vertigo. Several days after the vaccine I had a slight cough and sore throat. I am still experiencing a slight cough on some day sand a slight sore throat. I had a subtle red patch in the left shoulder area a couple days after the shot. Eight or nine days after the shot, I had covid arm and had a very visible red patch on my left shoulder. I have pictures of this. I have been feeling very tired and dizzy ever since the first shot. My glands in my neck under my jaw line are also swollen. I do not know if it is either wise or safe for me to get the second shot, which is scheduled for this Friday as it seems that I still have not recovered from the first shot. Can my immune system really take another round of this? There are a couple other things that I have noticed. I don't seem to be thinking very clearly and I have noticed a remarkable number of type-os and poor syntax in emails that I send at work; this is not normal for me. Finally, after the shot, I noticed that my muscles, when doing a little exertion such as pushups, would build lactic acid quicker and more blood seemed to be delivered to my working muscles. I still have not regained my strength and tire more easierly when playing tennis or hitting against the tennis wall, for example. This is also not normal and not how I felt before the first injection.

It started with body weakness; feverish; progressed to chills and high fever; moderate to severe body aches. And headaches severe sinus congestion. These lasted for about one week. I did Augmentin (I'm a dentist). I took Mucinex and Vitamin C, Zinc, and Levothyroxine and Theraflu. These helped my symptoms. I got skin rashes towards end of first week of the symptoms and they still haven't gone away. They are on my hand back part of the palm. It's itchy and raised. And I have them on my lower legs, as well. I have recovered from flu like symptoms but not from skin rashes.

Woke up at 3:30am to extreme swelling in my left cheek, went to the bathroom to check it out and almost passed out. Went to the hospital and was checked for a stroke. No stroke detected. While during the exam, my tongue started to swell up and they decided to insert a tube for breathing. Woke up on Sunday after the swelling went down and the tube was removed. Was released from the hospital on Tuesday. Maintained a fever that week and on Friday, my fingers on my left hand and my left foot started to swell again, almost passed out. Went back to the hospital for observation and treatment for a staph infection from the first hospital visit.

Soreness in shoulder as if I had been punched hard, rash oval/circle approx 5 inches in diameter, mild swelling under the rash, moderate fatigue, swelling of lymph node in arm pit opposite injection site like a squishy hand ball, severe sweats and chills, extreme urination, general body aches, general joint aches, aching of sports injuries less than 3 years old, mild nausea, mild dizziness, severe headache, swollen lymph nodes in both sides of neck, loss of taste, mild skin numbness around and above the rash. Most symptoms resolved after 4 days.

I am still having persistent chills, sore joints, swollen face, and brain fog (cognitive impairment). These symptoms have been persisting since I got the second shot and it has been 6 weeks now. I NEVER had these symptoms prior to the vaccine.

Note: May 24, 2021 the pharmacy that administered the COVID vaccines contacted me with some billing questions. When I mentioned my severe reactions, they told me they were filing a report upon my behalf. When done they told me it was the VAERS system and gave me a reference number (Ref-531994). I decided that not enough information would be in that report so wanted to submit myself because of my severe reaction and hospitalization. My PCP was not involved until after hospital for a follow up and I was seen by numerous doctors there, so I have no easy single POC until I dig more. Mar 26, 2021 Received first Moderna COVID vaccine lot 018B21A. Apr 13, 2021 Pain in knees begins and over approx. 18 hrs. increase rapidly to point of pain walking. Compression of knees to sit worse. Apr 14, 2021 Irritation in throat that felt like large amount of dry bread stuck. Cannot get rid of feeling. Lasts for approx. 36 hrs. Apr 16, 2021 Fingers begin randomly swelling one digit at a time with overlapping between fingers. Sections of my palms also (not entire palm at a time, just an area). Each swelling last between 18 to 36 hours. This swelling takes place from 21 Apr to 27 Apr. When a finger swells it becomes red, hot to the touch, and extremely itchy. I have pictures. Apr 17, 2021 Wake to find tongue hugely swelled. Thought I'd bitten in my sleep. Unable to eat, hard to swallow fluid past tongue. Lasts for a bit over 36 hrs. Apr 19, 2021 Knee pain begins spreading up thighs down calves. Pain also beginning in feet toes and ankles. Apr 20, 2021 Knee pain when bending prevents me from entering truck to drive. Apr 27, 2021 Knee pain eases slightly. Able to sit in truck for short period of time until too much pain. Apr 28, 2021 Receive second Moderna COVID vaccine lot 043B21A at 1pm. Apr 28, 2021 Approx. 2:30 pm knee/overall leg pain begins increasing rapidly to higher than before level. Over next three days increases to point where I cannot stand/walk due to pain. Unable to sleep due to pain also. Apr 28, 2021 Same Day-Around 4:30 pm notice voice is becoming raspy. By 6 pm my voice is completely gone. I have no voice for next approx. 36 hrs. Apr 30, 2021 Upper lip begins swelling in early afternoon. Enormous as everything else has been. Lasts approx. 36 hrs. but extremely tender for next 12 hrs. I have pictures. May 2, 2021 Go to ER in morning. Bloodwork/tests done. No conclusive results. Remain in ER overnight waiting for available bed at a hospital. May 3, 2021 Transferred by ambulance in afternoon to hospital. May 4, 2021 Begin seeing multitude of Drs. More bloodwork and testing. Still major pain w no relief. May 4, 2021 Suspected diagnosis is gout. I have never had gout diagnosed for me before but so be. May 4-7, 2021 Receive daily shot of anakinra. May 6, 2021 Begin noticing decrease in pain. Unable to get out of bed without help but attempting to use a walker. May 7, 2021 Lower lip begins swelling. Hospital staff injects BENADRYL. Even with, becomes, you guessed it, enormous. I have pictures. May 8, 2021 Discharged from hospital with walker. May 8-13, 2021 Required use of walker. Started using cane partially towards end date. May 14-present 2021 Using cane to walk. Less each day but still need for stability. Still have knee pain. Have higher level of pain in feet. I had/have a major reaction to the Moderna vaccine. This should be investigated and reported on. Thank you.

Patient is here with left upper abdominal pain and left chest pain that started last night. Patient had his second MODERNA vaccine on May 20, 7 days ago, has not felt well since then. Initially had muscle aches back pain fever or chills. Reportedly stayed in the hot tub too long and he may have gotten dehydrated. Patient had onset of left upper abdominal pain and left-sided chest pain last night. He took some over-the-counter medications without any relief. He has had a history of some stomach problems and IBS in the past but they usually resolve on their own.

I had pericarditis 2 years ago and 4 days after my 2nd dose of Moderna I felt similar symptoms to when I?d had it. They subsided after a day but came back 3 weeks later. Because of my history of having had Pericarditis I had ultrasound and CT Scan and they showed some inflammation. Blood tests showed C-reactive Protein levels high (70). On my own I googled if pericarditis was a side effect from vaccine as it was odd to me that my symptoms started so soon after. I read that there have been rare cases reported recently but mostly in young people and they?ve subsided. Perhaps because I had it two years ago it triggered a recurrent effect. I was prescribed 600 mg ibuprofen as before by Cardiologist and colchicine as before. My PCP suggested I might want to notify you. I thought I should report this given what I read and that I'm 55, so it?s different than other reports you?ve received. I do not know if I have pericarditis again but the symptoms have been identical to when I did and the CRP level increase would suggest so. I had Echo and EKG and heart alright so it's not Myocarditis. Symptoms included: pain in abdomen chest area, pronounced in URQ this time but it migrated, increased when walking or lying down, difficulty sleeping in side, slightly elevated fever 98.9-95 when I?m usually in 96-98 range, breath hiccups, some nausea. Since taking colchicine and ibuprofen have been feeling better, just concerned that this seemed to have recurred, and started exactly 4 day after my 2nd shot.

On 6/19 patient had had mild fever, sore arm (as expected at injection site), and general fatigue (as expected). On 6/20 both of his feet were swollen and it felt as if he was walking on marbles. 6/21 feet had gone down and were normal but later in the day lymph nodes in neck were swollen and he developed a lump on the back of his neck. On 6/22 the neck swelling went away but he then developed left hand and lower left arm swelling. On 6/23 the left hand/arm had gone down but the right hand/arm was swollen. On 6/24 patient experienced swelling around the eyes.

Wife called to report that patient developed a generalized rash throughout the body the night after receiving Moderna Covid shot. She provided him with Benadryl. Next morning his face was swollen and she decided to call the pharmacy. I advised her to provided Benadryl again and to take him to emergency room. Difficult breathing was not reported.

12 hours after vaccine I had severe muscle pain, vomiting, severe headaches, and swollen arm, dizziness and blurry vision and that lasted about 24 hours. 2 days after the vaccine in the morning, I was at work and about 10 am I got very dizzy to the point of losing my balance dizzy. I drove home about a 1/2 hour later. I drove about 90 miles stopped at stop light and experienced vertigo, I went to ER. As, I got out of car, they sent a wheelchair and asked me my symptoms and they immediately told me I was having a stroke. They did cat scan and injected me with TPA. After that they then asked me when did the symptoms started, I told them after my vaccine. They admitted me into the ICU of hospital.

Fever, chills, body aches, headache. Lymph node in right armpit swollen to size of a baseball. Have not received treatment.

arm pain, chest pain,lethargy, headache, swollen lymph glands, throat pain Narrative: Employee states: day 1: felt injection and symptoms immediately following in arm and left part of chest. Within the first hour, got very tired and could not work. A few hours later a headache persisted and lasted through thenight. day 2: still had headache but it became less persistant over time- would come and go throughout the day. Continued to fall asleep (at least 5 times) and difficulty staying awake. Some stabbing pains in the throat area. day 3: awoke with left underarm pain. Lymph glands are now swollen. two episodes of stabbing pain in my throat today.

Day 1: dull headache Day 2: dull headache, injection site soreness, muscle soreness, joint pain, lower GI distress Day 3: intermittent dull headache, injection site soreness, muscle soreness, joint pain, lymph node pain under same arm of injection, fatigue Day 4: injection site soreness, joint pain, lymph node pain, fatigue Day 5: Lymph node soreness

Light fever ,whole body muscle pain,(for two days) Lymph nodes in the side of the vaccine are swollen and painfull to touch (still present)

Hands and arm dermatitis rash 3 weeks after vaccination, possibly a delayed reaction to vaccine. Has topical steroid cream to apply to dermatitis sites from doctor staff member visited as well as zyrtec tablet for allergies once a day. Dermatitis sites have pruritus and are red and raised patchy rash areas. Large patch on left hand, small "spot" like raised red bumps on arms and right hand - diffuse, not many bumps.

Two and half hour after the shot on the 20th of january at 1:20 PM by 3:30 PM I felt a very unusual sensation ... I had a contrast cat scan before with dye and right after i was injected with the dye I felt inside heat or burning sensation ..two and half hours after the vaccine I had the same exact sensation inner heat and pain in my right side where the liver is or golbladder . Also lympho gland pain under the left arm injection site area my temp at all time was 98.6 to 99.4 never passed that number.. on january 22nd early in the morning I woke up and all these symptoms are gone the inner heat , pain in the injection site and pain liver area all gone . I had to report this because it is unexpected and unusual reaction .... but i am fine now my temp is 98.4 normal

Serious anaphylaxis started at 630 PM the day after the Moderna dose was administered . I ended up at the Medical Center ICU for two days before conditions abated and I could be discharged .

Painful swelling of hands and fingers, and pain in finger tipis. He had sensation of rash on upper back and shoulders but was unable to see if there was a rash. This lasted for 10 minutes.

Multiple adverse events. Most serious is the Swelling of the left knee cap area starting on Day 4 (1/29/2021), extremely swelling and pain left knee 1/30/2021, 1/31/2021, 2/1/2021 and reduced swelling 2/2/2021. Went to PCP on 2/2/2021 was referred to hospital for x-rays of left knee. Also right foot and leg were swelled on 2/2/21 and 2/3/21 the same area of prior Achilles Tendon surgery May 2018 and history of DVT Blood Clots June 26, 2018. Still experiencing swelling to left knee and, left ankle now and right ankle swelling. 1/26/2021 at 4:05 pm had charley-horse pain at right posterior thigh area left of hamstring from 4:05 pm to 4:15 pm then it disappeared. 1/26/2021 8:00 pm to 10:00 pain to right quadricept area then disappeared. 1/26/2021 around 4:30 pm to 1/29/2021 10:00 pm had random Itchyness episodes for 15 seconds then ok for a minute then 15 seconds itchy someplace else. The worst of the itchyness was for the first 48 hours.

Patient received first COVID vaccine (Moderna) on 2/4. On 2/9, patient states he had fevers, chills, headaches, and loss of taste and smell. He was tested through his workplace via Saliva PCR on 2/11, which resulted positive on 2/14. Symptoms began to resolve around the date of 2/21 for about 2 days. On 2/23, he started experiencing numbness in his fingers and toes along with severe nausea, vomiting, and diarrhea. He became so weak and ill, he presented to the hospital and was admitted on 2/26. During his hospitalization, he was seen by neurology, completed several tests including a lumbar puncture, nerve conduction study/EMG who diagnosed him with "likely some variation of AIDP, very possible mixed demyelinating/axonal variant".

Patient stated that he saw small bulge like appearance 45mins after the vaccine administration, close to jaw/behind the ear one side of the face. Since the patient noticed this and while talking on the phone, pt stated that it was already getting better. Patient also stated that later he was feeling numb on that same side, which his pcp advised him to take Benadryl. Benadryl helped with the adverse event.

Arm hurt 1st like bad tetanus shot for 2 days Chills & sweats started the next day or so Left arm lymph node swollen/aching Lightheaded, nauseous, nearly passed out & vomit Thursday night Chills & sweats got worse, very lightheaded, heavy legs, fainted when having seizure Saturday Sunday things seemed to subside * Tinnitus was flaring most of the time **Chronic left jaw ache/pain flaring as well ***Mid back pain spot which has become chronic like jaw wrapped around torso and up/down spine, almost like a cross. This seems to be the lingering issue as of sunday night.

Patient had Moderna covid vaccine #1 on 3/21/21. Patient presented to the emergency dept on 3/23/21 complaining of a discolored right arm (turning purplish) and swollen. Patient had a blood clot in Sept 2020 and was on anticoagulation until Jan 2021. Ultrasound of the RUE found an occlusive thrombus, R subclavian and right axillary vein as well as a nonocclusvie thrombus within the inferior R internal jugular. Patient was initiated on apixaban anticoagulation. Patient was seen back in the office and had a repeat ultrasound due to lack of improvement on 3/26, thrombus was unchanged. Patient continued on apixaban. Patient called the office on 3/29 with no improvement in his arm. Patient to be re-evaluated

Day1, vaccine time 9:30am, 4:30 pm , Herpies flare up around gums, feeling very tired. Day2-3 soarness left shoulder and neck, mild soarness on past hernia surgery sight and past skin cancer surgery site, Day 4 to present muscles and joints achey, feeling lethargic. No fever, but achy ness is similar to how I would feel with the flu.. 7 days feeling crummy

Right supraclavicular lymph node swelled to the approx size of an emu egg. Currently twice the size of a large egg. Shot was in the left arm

Next day patient experienced localized red inflamed area at site of injection with pain, developing into lack of mobility in left upper extremity. Non responsive to ice or heat treatment. Patient seen by orthopedic surgeon 2 days later. Bursitis confirmed by xray below deltoid. Treatment includes sling for 1 week and physical therapy for 1 month (still ongoing).

Left arm started swelling one day after shot, three days after shot swelling seems to be more. Second day arm was very hot to the touch. Third day arm is slightly less hot to touch but swelling looks worse.

rcvd shot 3/25/2021, symptoms started 2 days after ... two days later swollen neck glands , higher bp than usual, numb face...Mar 30 th 6:am faceial numbness, thick tongue, anaphylaxis went to ER, could not breathe , trouble speaking...by the time got to er BP diastolic was about 200. discharged after 4 hrs. Multiple body symptoms since include all over numbness, balance, Balance issues, fatigue, loss of taste, Heat spikes, myoclonus and stare seizures, sense of Euphoria, infusion, many more symptoms, contact me

55 y/o male with PMHx of obesity, LLE cellulitis (hospitalized in 2018), and varicose veins seen in unit 4/19/21 due to LLE cellulitis not responding to bactrim DS. Patient reports remote history of bilateral cellulitis and hospitalized once for IV abx for 4 days in 2018. He denies DVT history. He was prescribed compression stockings, unsure of compression grade but he isn?t wearing them due to the ongoing pain. He was seen by nursing on 4/2/21 reported leg erythema and swelling starting that day. He was given Rocephin and had Bactrim ordered. The leg swelling/erythema/pain improved minimally with Bactrim DS but still had symptoms so he was seen today. He reports posterior calf tenderness. he denies fevers, chills, sweats, dyspnea, chest pain, SOB, palpitation, abdominal pain, N/V/D/C at this time. exam shows LLE with anterior erythema, tenderness, warmth, and (+) homan sign. 1-2+ BLE edema. He was COVID 19 positive on 11/10/20 and again on 3/15/21. Received moderna on 3/9/21 and 4/6/21. Labs sent to local hospital show D-Dimer >1000 and CBC with thrombocytopenia to 111K per lab with 3+clumping.

Pt is a 55 yr old male 2nd Moderna covid19 vaccine on 2/11/2021 presented to the ER on 4/24 with c/o rlq abd pain x 1 day. CT scan with acute appendicitis. Taken to the OR for appendectomy.

5 days after first dose of Moderna Covid-19 vaccine, pt noticed his leg was swelling and told his doctor that his leg was swollen at a routine doctor visit that was scheduled ahead of time prior to vaccine. The doctor told the patient to go next door to vascular clinic. They did an ultrasound and found an acute DVT and chronic deep vein thrombosis. Pt was put on Eliquis the same day (4/12/21) to treat the issue. Mild swelling is still present in leg, but pt was cleared by Dr. to receive second dose which he did on 5/5/21.

Engorgement/Swelling of lower right extremity from hamstring to foot, significant discomfort in right calf weight bearing, flexion of right foot/ankle, and to touch (e.g., massage).

High fever 104.5 the evening of shot along with chills. 1st trip to urgent care on 04/28/21. No testing, doc recommend Tynol for fever. Fever decreased with meds but would spike once meds wore off. 6 days later welts/hives appeared along backside with swelling in groin area & left side of lips. 2nd trip to urgent care 05/02/2021 doc treated for allergic reaction by administrating a steroid shot plus prescribed 10mg of Cetirizine, Prednisone along with an Epi pen. Fever was at bay for 2 days but then resummed

Site: Swelling at Injection Site-Mild, Systemic: Allergic: Swelling of Face / Eyes / Mouth / Tongue-Mild, Systemic: Dizziness / Lightheadness-Mild, Systemic: Visual Changes/Disturbances-Medium

Throat closed could not swallow water, violently threw up 2 min after vaccine was given for over a hour straight, feet welled and dizzy. . Kept on-site for 3 hours after vaccination. has been in bed with a headache and flue symptoms for 3 weeks , intentional severe cramping and constant diarrhea. Severe body aches requiringg pain medication. Still currently having side effects a month later

Red and swollen arm a week after injection. The redness spread to the whole top part of the arm. The swollenness was so severe that it looked like muscle. Nodule formed under skin in the arm pit.

Approximately 9 days after the vaccination, tender left axillary lymphadenopathy, malaise, chills, and high fever (to 104F) developed; followed several days later by development of marked erythema and warmth over the left chest wall, left axillary region, and onto left back. This presentation required brief hospitalization for treatment of a presumed cellulitis and further diagnostic workup of fevers and lymphadenopathy. The patient was treated with antibiotics for cellulitis and empirically for possible tick-borne illness (early Lyme, glandular tularemia) with notable improvement in the skin erythema and fevers.

Swelling of the feet (2x size on right leg). Sensation of heat and needles to the plant of the feet. Continued sensitivity and numbness in right foot, heel and toes. Currently treating of the edema by compression, icing and ibuprofen and suspending all physical activity to relieve stress on legs. Saw Dr. on June 4th.

Patient brought to ED 6/8 am with substernal chest pain onset 6/7 pm. Tests include EKG, chest xray, serial troponin, Chest CT, BNP, d dimer, labs. Patient admitted for further work up which ruled out PE, aortic dissection, pneumothorax. Initial EKG showed ST changes in inferior lead and repeat EKG consistent with pericarditis. CXR showed pulmonary vascular congestion and prominent interstitial markings. WBC showed leukocytosis. Elevated CRP. Patient started on aspirin and colchicine with improvement and discharged home.

Within 24 hours of the first dose of Moderna COVID-19 vaccine I developed a meibomian gland infection and injected conjunctiva in my right eye. This resolved within 5 days. Within 24 hours of receipt of the second dose of Moderna vaccine I developed identical signs and symptoms in my right eye as well as a stye in my left eye and massive lymphadenopathy and swelling in my left axilla (the arm of vaccine administration for both vaccinations). The eye conditions resolved within 10 days. However, the lymphadenoapthy persisted for at least 4 months, with moderate resolution. I continue to have some painless swelling in my left axilla.

Patient complains of shortness of breath, very sore arm, inflamed lymph node under left arm, chills, fever and heart arrhythmias, Patients states he was in perfect health before receiving the Moderna Vaccine. He refuses to go to a doctor for evaluation. The request that I complete VAERS

My arms swell and I had a fever. My glands were swollen and the fever lasted 4 days. On the 4th day, the swelling went down but it didn't look right so that's when I went to the Emergency room where they did the EKG. They let me go and got in touch with my doctor which I got an appointment on the 29th. I am experiencing heightened senses and pain. The pain is really bad in my forearm and elbow. It feels like it is weaker than what it was. I can't lift my arms over my head. It is more intense after the vaccine was administered.

On 6/2/21, patient c/o decreased range of motion and pain about 3-4 days after receiving 2nd dose of Moderna. Office visits on 6/4/21 and 6/10/21 for bursitis with Celebrex 200 mg capsules prescribed once daily on 6/4 and twice daily as needed on 6/10.

difficulty breathing during a regular exercise time and eventually even walking at all due to severe water retention, after visiting my doctor and having an exam as well as an ekg he determined that i was in afib/congestive heart failure. i was sent to a heart doctor who performed a cardio version which did not convert my heart, later i was hospitalized for the afib and water retention and another cardio version was performed and again it was not successful for more than a day. i am currently scheduled for a cardio ablation on 7-9-21.

beginning in the evening after the shot I noticed a red area starting to appear around the injection site. Early in the morning of June 24, approx 1:30 AM I awoke with severe joint and muscle pain over my entire body with a pain level of 10. I had tears uncontrollably running from my eyes due to the pain. Friday June 25, the muscle and joint pain had dropped to a level of 6 to 7. and I was able to realize that I also was having a severe migraine unlike any I have ever had before. I also notice that I had been having swelling in my hands and feet, dizziness and some cognitive issues. My hands hurt enough that I was unable to make a fist. The migraine after 4 days dropped down to a bad headache and that lasted 11 days. I still have been having off and on headaches with them intensifying to migraines and since the shot have had a total of 12 migraine days. My hands are still swelling and varies from day to day. It has also affected the migraines that I have suffered from and intensified them and changed the location of where I feel the pain. The Chronic Pain that I have been suffering prior to the shot that was 80% under control is now down to 40% controlled and I am having difficulty walking and being able to hold things in my hands. I am afraid that the vaccine has perinatally changed and intensified the migraines and pain issue and regret ever being pushed into receiving it.

Allergic reaction which came on without a known specific reason. face swelling and elevated blood pressure,

Swollen lymph nodes, chills, body aches, sore injection site No treatment, symptoms lasted over night

Itchiness starting with both hands front and back on day 7 progressing to itchiness to top of both feet and both elbows. Noticeable raised red lesions on day 9. Cortisone cream and lidocaine cream minimally effective. Will try one Benadryl cap before bed. Will consider pcp office visit if sx do not resolve by Monday (day 14).

approximately 40 minutes after the vaccine I developed a mild head ache that lasted about 1/2 hour. That night I woke up due to injection site pain that lasted through the night. Friday morning I realized my lymph node was swollen. By Saturday all symptoms had resolved.

left arm pain, swelling and redness fatique, headache, muscle pain, joint pain, chills, nausea and fever

This man developed fever (102 degrees, body aches, headache, joint pain, muscle pain, and a grapefruit size swelling in axilla area. His physician prescribed antibiotics and told him it was a reaction to the vaccine.

January 31-Feb1 Fever to 102.7, muscle rigidity, spasm and pain, bone pain over entire body lasting 7 hours overnight, tylenol 1000mg fever broke and pain subsided. Wanted to call 911. Feb 1st muscle pain increased during the morning and by noon fever of 102.5 with extreme fatigue, tylenol 1000 mg, unable to work. Injection site intense pain radiating down to wrist. Feb1st overnight sweats and bone pain, muscle pain tylenol 1000mg, injection site pain and redness appearing similar to a sunburn near injection site, swelling of lymph nodes under right arm with pain. Headache, moderate to intense. Feb 2nd fever to 100.5 with moderation of the above symptoms. Asthma chest tightness, asthma related productive cough. Tylenol 500mg every 3-4 hours, working from home. Headache continues moderate level. Feb 3rd, no fever all symptoms continue with injection site pain, new increased asthma related wheezing. Tylenol 500 mg every 4 hours. Headache continues with fatigue. Feb 4th, no fever, symptoms moderating, asthma and allergy symptoms increasing. Fatigue increasing. Itching of injection site. Feb 5-current. No fever pain in injection site and lymph node area is moderating, still with Fatigue, Headache, Asthma and allergy symptoms staying steady with period of increased levels. Tylenol 500 mg 6-8 times a day.

Moderna Covid-19 vaccine EUA. Rapid heartbeat, tingling and numbness in extremities, face, tongue, dizziness, swollen lymph node, blood taste in mouth. I?ve been to the ER three times and they can find nothing wrong with me but I am not well.

rash, hot, tingling, swollen face, given 50mg benedryl... this happen again on the 9 Febuary 2021 and again on 13 Febuary 2021 treated with 50 mg benedryl po.... symptoms relived within 90 minutes... there was no difficulty breathing, swallowing or talking at anytime rash, face swelling, itching, tingling, hot,

45 minutes later, developed angioedema of face and lips. Airway patent. Rash on left flank. Was given 50 mg of Benadryl PO and sent out 911. Returned with orders for Prednisone 50 mg for 5 days.

Patient developed lower extremity weakness, the weakness progressed and after few days he was not able to walk even with help of crutches. Guillain barre syndrome was suspected. He was sent to hospital. Lumbar puncture was performed on him showed elevation of CSF protein. He received IVIG and his weakness improved. He also received Vitamin B12 injection due to Vitamin B12 deficiency

Patient informed the clinic that he began feeling "itchy like bugs crawling all over" on 2/16/21. He proceeded to take Benadryl which was effective. On 2/20/21 he woke up with swelling on the left side of his face. On 2/21/21 he woke up with swelling on the right side of the mouth and reported "tingling like I just went to the dentist". Symptoms were resolved by 2/22/21.

Anaphylactic reaction; A spontaneous report was received from a physician concerning a 56-year-old, male patient, who received their first of two planned doses of mRNA-1273, and who developed anaphylactic reaction. The patient's medical history included blindness and severe allergies to shellfish. Products known to have been used by the patient, within two weeks prior to the event, included Losartan and Melatonin. On 28 JAN 2021, approximately 15 minutes prior to the onset of the symptoms, the patient received their first of two planned doses of mRNA-1273 (Batch number: 032L20A) intramuscularly in the left arm for prophylaxis of COVID-19 infection. Patient's wife called to indicate that her husband had an anaphylactic reaction to the mRNA-1273 vaccine. Patient received the vaccine on 28 JAN 2021 in his left arm. Patient's wife indicated that her husband texted her at 3.21 pm to let her know that he has gotten the shot, indicating that he must have received it around 3.19 pm. Patient's wife indicated that around 3.34 pm, patient said he'd had an anaphylactic reaction, that he had administered a shot of epinephrine and that an ambulance was on its way. The patient's wife noted that the reaction happened within 15 minutes or so. Once in the hospital, the patient was administered Pepcid and Steroid orally. Additional treatment medication for the event included the previously epinephrine and a shot of Benadryl. Action taken with mRNA-1273 in response to the event(s) was not provided/unknown. The outcome of the event was unknown.; Reporter's Comments: Based on the current available information and temporal association between the use of the product and the onset date of the event, a causal relationship cannot be excluded. Patient's significant medical history included severe allergies to shellfish.