Pfizer

Lethargy, chills, shaking, pale, slightly tachycardic. Afebrile initially then fever presented after about an hour to 103.3

PATIENT GOT HER FIRST COVID PFIZER VACCINE AT 12/31 IN THE AM. HAD GOTTEN FLU LIKE SYMPTOMS AND HAD BEEN SICK FOR A COUPLE OF DAYS. HAD NAUSEA AND VOMITTING DURING THIS TIME AS WELL. ON 1/3 THE CARE GIVER WENT TO CHECK ON HER PT AT HER LTC FACILITY WHERE SHE LIVES AND SHE WASN'T ACTING RIGHT. SHE WAS UNABLE TO DO A STROKE EXAM. PT HAD NO MOVEMNET IN ARMS OR LEGS AND WAS UNABLE TO SPEAK. PT WAS VITALLY STABLE AT THE TIME. EMS RECORDED THAT THEY THOUGHT DIAGNOSIS WOULD BE STROKE, PNEUMONIA OR SEPSIS. AFTER ARRIVAL AT THE HOSPITIAL DETERMED THAT SHE HAD A STORKE, ACUTE KIDNEY INJURY, ABNORMAL LFTS.

Presented with stroke like symptoms at 10:30, right sided weakness and slurred speach. 911 was call, patient was transported to hospital. Per ED note, patient experienced TIA which resolved, actue exacerbation of CHF. Patient was admitted. Discharge summary on 1/22 indicates same diagnosis, plan was home with hospice. Family notified hospital on 1/25 that patient had expired on 1/23 at home.

AS (aortic stenosis); Cardiac syncope; Pancytopenia; Severe aortic valve stenosis; Symptomatic anemia; Syncope; Syncope, unspecified syncope type

Abnormal chest x-ray; Altered mental status, unspecified altered mental status type; Arrhythmia; Bradycardia; CHF (congestive heart failure); Cardiac arrhythmia, unspecified cardiac arrhythmia type; Essential hypertension; Heart failure with preserved ejection fraction, unspecified HF chronicity; Hypothermia, initial encounter; Pneumonia of right middle lobe due to infectious organism; Right middle lobe pneumonia

On 2/5/2021 resident noted to be azotemic. Creatinine up to 3.8 and BUN in 80's. He was started on NS hydration. On 2/7/2021 he was noted without VS, per MD notes, possible VF arrest, renal failure; death unclear exact cause.

Temp 103.5 temporal, myalgia, SOB, loss of balance, SpO2 85% RA lying down Symptoms appear to be resolving this AM. Sp02 98% on 2L O2. Temp 98 temporal - at 7:45am

Uncle received vaccine on 2/9/21 at 11:30am. Had acute myocardial infarction on 2/10/21 at 08:30am where he proceeded to fall and fracture hip. Transported to emergency department and treated for AMI. Stabilized and taken for surgery to repair hip fracture. To be discharged on 2/15/21 to rehabilitation facility. Up until this point he was very healthy and active, despite his age, living unassisted at home.

emergency Room HPI This is a 90 y.o. male who presents presents in the emergency room by ambulance from local nursing home for complaint of fall with no localized pain but was said to have low blood pressure of 80/40 and low O2 sat of 77%. PCP said to send patient to the ER for evaluation. Patient is COVID positive but is said to have completed the vaccine on 19th of January 2021. In the ER blood pressure is 122/71, respiration 18, pulse is 68, temperature 98.7° F and O2 sat of 95% on 4 L. Patient is confused and not answering questions which is his baseline.

2/24/21 Patient Died. 02/23/21. Patient came to ED for weakness/falls. Patient had fallen on 02/21 and 02/23. UA was done in LTC, and he was started on ciprofloxacin 02/22/21. Treatment was to put patient on comfort cares (morphine + lorazepam)

Caller is nephew of patient. Patient was admitted to Hospital on 2/15/21 with Covid like symptoms and decreased O2 sat. He tested positive for Covid 2/15/21. Treated with Remdesivir. Patient status continued to decline and he passed away in hospital 2/22/21 0612.

Severe abdominal pain unable to eat or sleep for 36 hours. He went by ambulance to the Hospital emergency room. They tried to pump his stomach but he aspirated and and went into cardiac arrest. He was revived but never regained consciousness. (The ICU Dr said that he had blood clots in his abdomen from a recent stroke. We were unaware of him having a stroke other than in 2026. The same Dr. said that he had necrosis in his lungs from aspirating. The necrosis was from his bowel dying) He was put on a ventilator and given drugs to increase his heart rate. On 3-5-21 the heart drugs were reduced and he died. I was with him when he recieved the vaccination and he was healthy, just old. I think that the shot killed him.

Pt reported chest tightness similar to reaction after 1st vaccination. Vital signs were stable. Physical exam was within normal limits. Pt was observed in medical tent for 30 mins with symptom resolution

3/17/21 ER Nurses' Triage note: "To Er via EMS for eval of AMS and low oximetry as reported by nurse at the rehab and long-term care facility. States he has not been his "normal " self the last few days. Upon arrival here patient is alert and verbal. Laughing with staff, poor extremity circulation shows varying oximetry, but after warm blanket applied oxi 99-100% 2lpnc. Is bradycardic with cardiac monitor showing 3rd degree block"

Within 10 minutes my father developed shortness of breath, diaphoresis, elevated blood pressure, and elevated blood sugar. His blood sugar was 318. My father is a type ll diabetic and has never had a blood sugar over 200. His blood pressure was elevated at 160/90 and it normally runs 120/70. Symptoms resolved within about 2 hours.

Blood pressure dropped dangerously low, dizzy, weak, off balance, exhausted, achy, headache, nauseous

3/5 Patient presented to ED after being found on floor at home and complaining of neck pain. primary care giver noted that patient had had several recent falls, increasing weakness and decreased appetite for several days prior to presentation. Pt was found to have UE weakness in ED and cervical spine CT showed C2 fx and cord hematoma resulting in severe cervical stenosis. Screening nasal swab for admission was positive of SARS-CoV-2. Pt had no hypoxemia. 3/6 pt was intubated for acute hypoxic hypercapnia secondary to hypoventilation from medication. The was then found to have MRSA pneumonia. He was treated with both dexamethasone and IV vancomycin. 3/8 had C2-C6 laminectomy Progressed slowly and was extubated and worked with PT/OT/ST. Found to have occult sacral fx. Was eventually discharged to SNF on 3/17/21

@nd dose Pfizer on March 27 without immediate problems. Had sudden collapse on March 29, found to have large intracerebral hemorrhage; at local hospital after discussion placed on comfort measures only; died 04/02/2021

Death Hypokalemia LBBB (left bundle branch block) Pneumonia Anemia Hypoxia Fever Multifocal pneumonia Pneumonia due to COVID-19 virus2.82 Sepsis

Significant drop in blood pressure, nausea, dizziness, significant decline in functional capacity- fell x 2 , was independent now requires full hands on assist for Balance and fall prevention

After the second shot, my father began coughing worse and it appeared his COPD exacerbated, as well as progression in memory loss and confusion. His oxygen levels decreased and his blood work showed low platelets, so he was admitted to hospital on March22-23. Discharged with recommendations to see hematologist. Bone marrow biopsy indicated a very rare form of leukemia (Hairy Cell ). Cancer likely not a cause of vaccine of course, but suspected low blood platelets and exacerbation of COPD?

PFIZER-BIONTECH COVID-19 VACCINE EUA. PATIENT RECEIVED FIRST DOSE OF VACCINE ON 2/8/21. PATIENT REPORTEDLY PASSED AWAY ON 2/13/21 AT 7AM IN NURSING FACILITY. Record of death states CHF as principle cause of death and Stage IV CKD as contributory cause of death.

Death Narrative: Patient was previously tested COVID-19 positive on 3/2/2021, but did not have any other predisposing factors(PMH, allergies, etc.) for experiencing an adverse drug event. The ADR did not occur at the time of the administration of the vaccine nor was there an ADR that occurred between the observation period and the date of death. Patient was admitted with afib with RVR on 2/17/21 and was having a HFrEF exacerbation. HR was controlled during admission and he was discharged on 2/19/21. Patient was hospitalized 4 more times over the next two months for cardiac symptoms with last hospitalization occurring 4/12/21 for hypotension/tachycardia and decompensated heart failure. Patient never recovered and transitioned to hospice before passing on 4/16/21. Patient had a PMH significant for afib s/p DCCV on eliquis, CKD, HFpEF on home O2 2L, PMR on prednisone, known R pleural effusion, Covid PNA in 11/2020 and chronic foley

Swollen left leg noticed on 3-19-2021 as a result of blood clots identified by ultra sound on 03-31-2021

Patient presented to the ED and was subsequently hospitalized with acute respiratory failure with hypoxia within 6 weeks of receiving COVID vaccination.

Patient was a healthy, active man, walked the dog 2x a day, wrote about classical music, etc. until 02/23-26/2021: Atrial fibrillation episodes that would not resolve themselves; 03/03/2021: Cardioversion at Hospital which did not work; medications were changed or adjusted over the next weeks, Metoprolo tartrate 25mg was added 03/10/2021. Patient was anxious, napped during the day, couldn't sleep at night, couldn't concentrate on anything for any length of time, breathing irregular, had no energy to walk; 03/11-16/2021: in Hospital 04-10-14/2021: in Medical Center, for ablation and pacemaker. Great improvement, had more energy, was ale to drive again but was not back to his active self pre- 02/23/2021. Medications as of 04/27/2021 were Allopurinal 300mg daily; Atorvastatin 10mg, daily; Eliquis 5mg 2x a day; Furosemide 20mg daily; Melatonin 10mg, daily; Metoprolol succinate ER 50mg daily; Valsartan 40mg, daily; Adult 50+ Eye Health, daily; multivitamin, 1 daily; Docusate sodium 50mg as needed. By 05/26/2021, the patient is once again sleeping off and on during the day, has no energy, coughs more, can't concentrate, has lost his appetite, is anxious and discouraged. His speech is often muffled instead of clearly enunciated as is his wont. The medications have been adjusted again: as of 06/07/2021, Metoprolol 200mg, daily; Furosemide 40mg daily; the other medications remain the same. The patient, over the more than 3 months, has had xrays, electrocardiagrams, CT scans; bloodwork done. The question is: is it possible that these seemingly uncontrolable atrial fibrillation episodes are an adverse reaction to the second Pfizer vaccine? Has research been done on the vaccine and cardiac problems?

Around 15 minutes after receiving vaccine, patient started to stare off into space(blank stare). He was sweating, pulse was very weak, and he started to drool at the mouth. Wife kept stating that he did this at home sometimes and it was not related to the shot. Epi was administered and ambulance was called. Before ambulance arrived, patient started to respond to wife and HD personnel. EMT's evaluated him and wife did not want him to go to the hospital. EMT's agreed.

Resident admitted to Hospital on 6/29/2021 for hemiplegia. Diagnosed with a cerebral infarct. Resulting aphasia and right hemiplegia.

SUSPECTED CVA; BRADYCARDIA; FACIAL DROOP; SLURRED SPEECH; WEAKNESS; DYSARTHRIA; ALTERED MENTAL STATUS; HYPERTENSION;HYPOKALEMIA; ISCHEMIC CARDIOMYOPATHY; LEFT BRANCH BUNDLE BLOCK; RHEUMATOID ARTHRITIS; RIGHT SIDED WEAKNESS; TYPE 2 DIABETES MELLITUS WITH DIABETIC NEUROPATHY STARTED ON 7/4/21 AND PATIENT WAS HOSPITALIZED UNTIL 7/8/21. CARDIAC ARREST; ACUTE ENCEPHALOPATHY; ALTERED MENTAL STATUS STARTED ON 7/9/21 AND PATIENT WAS HOSPITALIZED UNTIL 7/12/21.

Patient experienced a heart attack 5 days after Covid 19 Injection and then a Stroke. Hospitalized for 3 weeks and had 2 months of Rehab.

Patient developed hypoxia on 1/4/2021 and did not respond to maximal treatment and passed way on 1/5/2021

Patients wife called for help and said he seemed to be asleep. Staff helped hold him up so he did not fall out of his walker. He did have a pulse and appeared to be breathing. We removed his mask to make sure airway was not blocked. He was not responsive to verbal or physical cues. 911 was called. Patient was laid on ground and had bp checked by emergency services. He did wake up but was taken to hospital.

Patient stated he was feeling weak and sick at 1415. Reported problems with diabetes and hypotension. Blood glucose checked using patient's own machine and was 200. EMS called at 1430, arrived at 1435. HR 88, BP 78/40 (family states usual systolic in the 80s). EMS recommended transport to the ED for IV fluids, but family refused. Patient left site at 1445.

On 1/9/2021 observed with elevated respirations of 38-42 per minute, BP manually 72/50. pulse is jumping rapidly between 110-16 bpm. oxygen sat 76% RA, resident refusing oxygen at first attempt, allowed oxygen to be placed, is now 84% on 4L. resident shaking head yes that he is hurting, and yes that he would take medication for pain. Dr. notified, branch block. Received order for morphine 2mg per hr as needed for elevated respirations and pain. Dr. also gave orders to D/C Tamsulosin and finasteride. Resident continue with decreased O2 sats and elevated respirations. Absence of vital signs on 1/10/21 at 826PM.

I faint anf fell twice hurt my back once; I faint anf fell twice hurt my back once; hurt my back once; Dizzy spells; Constipation; This is a spontaneous report from a contactable consumer (patient). A 91-year-old male patient received the first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, lot number: EL1284) via an unspecified route of administration in Jan2021 (a week before reporting) at single dose in left shoulder for COVID-19 immunisation. Age at vaccination was 91 years. The patient's medical history and concomitant medications were not reported. About 24 hours after shot he started having some dizzy spells and then fainted and fell a couple of times and hurt his back once. He stated he also had had constipation since the shot and do not know if that is related or not. The patient wanted to talk to see if he could get his second shot. He is taking some pain killers for his back. With regards to Physician Office/ Emergency Room: patient stated, 'This for my back and nothing else of that'. The outcome of the events was unknown. The information on the lot/batch number has been requested.

DIAGNOSIS: #1. CVA #2. Aphasia, acute Number 3. Change in mental status, acute ASSESSMENT/PLAN/DECISION MAKING: Spoke with radiologist informed me that patient had a deep ischemic or infarct change in his corona radiata area which is common in patients with covid 19 infection or vaccination, which patient had a day and a half ago after lengthy discussion with wife, she informed me that patient would not want CPR and he had a stroke in the past and does not want to go to another city as he is 91 years old and therefore not a candidate for thrombolysis and also this was a wakeup stroke and so we do not know his exact time of onset, and she states that they simply want to be treated here for comfort care.

Patient (now deceased) received 1st dose of Pfizer-BioNTech vaccine around December 21, 2020 and was noticed to be scratching, fatigued, and unresponsive by a family member on December 24, 2020. He received the second dose of the same vaccine around January 22, 2021. Pockmarks and bleeding scratch marks were noted by a family member on the patient's face prior to this second dose. On January 28, 2021 a family member was alerted that the patient was suffering from severe bullous pemphigoid- a skin condition that has never been experienced by the patient, has been reported to be related to COVID-19 viral infection, and to T-cell responses promoted by vaccines. A corticosteroid was given, but did not work. Blisters developed to the point hands had to be dressed.

Patient was not seen at our facilities prior to or after COVID-19 vaccination. Patient received first dose on 1/23/2021 and as reported by the family member, patient expired on 2/5/21. Symptoms were reported to have stared on 2/1/2021, 9 days after receiving the first dose with a drop in oxygen levels and fever. He was reported to also have a history of chronic lung disease. Patient's family member to be contacted if necessary.

Emergency room HPI Patient is a 91 y.o. male who presents from nursing home with positive coronavirus a and flu A positive tests. Test was done yesterday. Patient sent to ER because of low oxygen saturation. Patient unable to answer or respond to questions. No fever or chills, no cough or shortness of breath and no complaint of pain when patient was moved around. Oxygen saturation on presentation was 89% on room air and went up to 93% on 4 L of oxygen admission: HPI: Patient is a 91 y.o. male with a history of severe dementia and severe COPD. He currently resides at Rehab. He had a routine coronavirus (COVID-19) test yesterday that was positive. Then, today he started having increasing oxygen requirement. He was not responding to his typical breathing treatments or oxygen and so they sent him in. In the ER he was found to be in some respiratory distress and did require increased oxygen concentration. Once they got him calm down, his oxygen saturation state over 90% with 4 L. His ABG did show an oxygen Saturation of 86% on 4 L. The patient reportedly had coronavirus (COVID-19) several months ago, but then did test positive for both coronavirus (COVID-19) and influenza on rapid testing at the nursing home yesterday. The patient is being admitted due to his increasing oxygen requirement and respiratory distress

Patient presented to ED for DVTs, currently being treated with warfarin and heparin bridge. Patient remains in the hospital at this time. Per the EUA, hospitalizations are to be reported irrespective of attribution to the vaccine

Pain in his lower extremities and torso. Pain on breathing inspiration, and observed with a nosebleed.

syncope; nausea; vomiting; This is a spontaneous report from a contactable consumer (patient). A 91-year-old male patient received the first dose of bnt162b2 (Lot/batch number and Expiration date were not provided), via an unspecified route of administration in right arm on 18Feb2021 13:00 at single dose for covid-19 immunization. Medical history included dementia, diabetes, chronic kidney failure, known allergies: pencillin. Concomitant medication included insulin, metoprolol, memantine, omeprazole (PROTONIX), apixaban (ELIQUIS). On 20Feb2021 21:00, the patient experienced syncope followed by nausea and vomiting lasting about 4 hrs. No treatment received. Events resulted in Doctor or other healthcare professional office/clinic visit. The outcome of the events was recovered on 21Feb2021 01:00. Information on the lot/batch number has been requested.

Patient fractured his hip and 2/22, underwent hip surgery, discharged to but readmitted with R lower DVT and bilateral pulmonary emboli.. Treated with IV heparin. Per EAU, hospitalizations are to be reported irrespective of attribution to the vaccine.

Client received Pfizer vaccine lot number EL9265 IM left deltoid on 2/1/21 and then received Moderna vaccine lot 03120A left deltoid on 2/20/21. His neice states he has not had any reactions initial reactions with the vaccine. She reports he was on hospice due to Congestive Heart Failure and died on 3/5/21

Only received 1st round dosage of COVID vaccination, he seemed to handle vaccination okay. On January 17, 2021, he tested COVID positive on a resident screening test done in response to an employee positive case in days previous to the residents testing. Fifteen days after his first innoculation,his AM nurse found him non-responsive on early vital checks. Vitals at that time were normal range. The facility physician was contacted and advised that he should be taken to Emergency Room at local hospital for further evaluation. Blood work was taken and ER DR diagnosed Heart enzymes elevated indicating a heart attack. Advised additional testing should be done, and that monoclonal antibody treatment wasn't an option due to time lapse since diagnosis of COVID, The option of comfort care was chosen as the treatment plan.

Severe pain in hip where he had a partial hip replacement. His blood pressure was extremely high from the pain. I thought he had broken his hip so I took him to the Orthopedic doctor who x-rayed the hip and said that there was arthritis flaring up causing this problem. A few days later, the pain was gone but he had developed a problem swallowing and aspirated leading to pneumonia. Even after the pneumonia was resolved, he was unable to drink or eat. He was placed on a diet with mush and honey liquid and died a week later.

Patient was seen and examined at the bedside. The patient is a 91 yr/o male with a history of CHF, NSVT, aortic stenosis, atrial fibrillation, HTN, hypothyroidism, DM2 who presents to the emergency room with complaints of chest pain and worsening shortness of breath. He reports he got his second Covid vaccine yesterday and was feeling well until about 1 AM when he woke up acutely short of breath. His wife checked his oxygen and reports he was 90% on his home 2 L. He felt he could not breathe unless he was sitting straight up. He changed over to his CPAP and was able to breathe and fall asleep comfortably. Today throughout the day his shortness of breath has persisted and he was due to see his cardiologist so they went to his appointment. While at the appointment he developed substernal chest pressure. It did not radiate. It resolved with 2 sublingual nitroglycerin. Patient was transferred to the emergency room for further evaluation. Patient denies any fever or chills. He has a chronic cough with clear sputum unchanged. He reports worsening lower extremity edema over the past few days. He reports he has been taking all of his cardiac medications as prescribed. Work-up in the emergency room concerning for acute on chronic CHF exacerbation. Troponins mildly elevated but are plateaued. No further chest pain while in the emergency room. Patient to be admitted for further evaluation and treatment

Patient tested positive for COVID 19 by PCR on 4/15/21; >2 weeks after 2nd dose Symptoms started 4/3/21; now w/ SOB w/ exertion, cough, chills, diarrhea, fatigue, chest pain/tightness, fever.

Death Narrative: Patient was not previously Covid positive and did not have any predisposing factors(PMH, allergies, etc.) for experiencing an adverse drug event. The ADR did not occur at the time of the administration of the vaccine nor was there an ADR that occurred between the observation period and the date of death. Patient was 90 and suffered cardiac arrest at home on 2/25/21. Patient had afib w/ a pacemaker, cardiomyopathy, CKD4, and PVD.

stroke with worse deficiency in right arm-weak, very little use in arm/hand as of 21May2021; right arm, soreness in arm; neck and shoulder pain began along with weakness in right arm; neck and shoulder pain began along with weakness in right arm; neck and shoulder pain began along with weakness in right arm/ with worse deficiency in right arm-weak, very little use in arm/hand as of 21May2021; General body weakness; This is a spontaneous report received from a contactable consumer (patient). A 91-year-old male patient received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), at the age of 91-year-old, via an unspecified route of administration, administered in arm right on 18Feb2021 at single dose for COVID-19 immunisation. Medical history included arthritis. Known allergies: amoxicillin. Concomitant medication included verapamil HCL; furosemide, potassium chloride (LASIX + K); colecalciferol (VIT.D3); magnesium oxide (MAGOX); atorvastatin calcium; warfarin. The patient previously received the first dose of BNT162B2 on 28Jan2021 at the age of 91-year-old for COVID-19 Immunisation, no issues whatsoever. The patient was not diagnosed with COVID-19 prior to vaccination. The patient had been tested for COVID-19 since the vaccination. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. The patient experienced stroke with worse deficiency in right arm-weak, very little use in arm/hand as of 21May2021 on 24Feb2021 02:00, right arm, soreness in arm on 21Feb2021 , neck and shoulder pain began along with weakness in right arm on 21Feb2021, general body weakness on 21Feb2021. Adverse events resulted in emergency room/department or urgent care, hospitalization (in 2021 for 3 days), life threatening, disability or permanent damage. It was unknown whether treatment received for the events. The patient underwent lab tests and procedures which included Covid test type post vaccination: blood test: negative in 2021. The outcome of the events was not recovered. No follow-up attempts are possible; information about lot/batch number cannot be obtained.

Lungs filled up - CT scan looked like glass - similar to COVID19 patients Had multiple COVID 19 tests all negative o2 levels very low in hospital for 12 nights to stablezize

Patient admitted to hospital on 03/24/2021 for high fever and shortness of breath; these symptoms began in 3/17. Patient tested positive for COVID-19 on 03/21/2021 and again on 03/24/2021 despite being fully vaccinated against COVID-19. Patient died on 04/19/2021. COVID-19 is listed on the death certificate. Death Certificate Information: Part I Cause of Death: A. Acute Hypoxic Respiratory Failure B. Suspected pulmonary embolism Part II: Significant Other Conditions: COVID 19 subacutely

91 y/o male, BMI 38, PMHx CHF, dementia, HTN, and paroxysmal Afib, admitted for acute onset altered mental status, SOB, Covid19, and pulmonary edema on 4/12/21. No reports of fever but tested positive for Covid19. Chest x-ray presents cardiomegaly with bibasilar opacities suggesting atelectasis and/or pneumonia. Covid treated with supportive care. Discharged home with hospice on 4/14/21.

Resident returned to the memory support unit at 1500. Resident was than toileted and transferred in to bed per his request. At 1515 resident was observed face down beside bed, resident sustained a 1inX1in eccyhmotic/hematoma to the forehead. Neuro Checks with in normal limes Vital signs: 100/52, 100, 97.2, 28. Resident sent to ED for further medical evaluation via EMS.

Felt like his throat was closing. He was given 25mg benadryl and then developed dizziness, heart racing, chest pain, shortness of breath, jaw pain. Was in SVT on arrival to ED

Patient stated he wasn't feeling well on January 25, 2021, wasn't eating and complained of abdominal pain. Patient noted to have indigestion and was constipated. Meds provided and labs ordered. On morning of January 26, 2021, patient became weak, lethargic and hypoxic and was sent to emergency department around 0700 hours on January 26, 2021. At approximately 1100 hours, emergency physician notified this writer that patient was not going to overcome his illness and would be placed on comfort care. At approximately 1130 hours, this writer was notified that patient had passed away from multi-organ failure.

Client tested positive for COVID-19 by rapid test on 1/8/21. On 1/9/21 at 1405 his oxygen saturation dropped to 86% and oxygen was initiated at 2L per nasal cannula. A non-productive cough was noted on 1/10/21 and oxygen was increased to 3L. On 1/12/21 Client became non-responsive with 30 second periods of apnea. Dexamethasone was initiated on 1/13/21. Lung sounds were noted with crackles on 1/15/21 at 1158 and at 2120 Client was unresponsive and without vital signs. Orders were for DNR and CPR was not initiated.

Since receiving the COVID-19 vaccine, patient has been sleeping 20 hours a day with decreased oral intake. On 1/30, his mobility began decreasing and he was no longer able to use the walker he normally uses. He is also usually alert and oriented x 4, altered (including hallucinations) when admitted to the ICU on 2/1/21. Also with hypertension and AKI. Management: precedex for agitation, labetalol for hypertension, fluids and foley for AKI

Ischemic stroke on Saturday morning following vaccine Thursday. Symptoms were muscle weakness and inability to speak

Patient was referred to the ED by his cardiologist for bradycardia. Patient underwent a procedure to have pacemaker placed. He remains hospitalized at this time. Per the EUA, hospitalizations are to be reported irrespective of attribution to vaccine.

Experienced coughing and vomiting during post vaccination observation period. Slightly elevated BP and pulse oximetry 90% on room air. Transported to ED, at triage stated feeling better, no further nausea or vomiting. Pt left ED before receiving an care. Telephone call to home, wife reported pt feeling fine, no issues.

he is shrinking now; He collapse while he was in the shower; weak/been getting weaker and weaker; feeling more unwell every day; This is a spontaneous report from a contactable consumer. A 92-year-old male patient received first dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE; lot number and expiration date unspecified), via an unspecified route of administration, administered in left arm (also reported as left upper arm) on 05Mar2021 as single dose for COVID-19 immunisation. Medical history included Kidney cancer, bladder cancer, colon cancer, mantle cell lymphoma and was compromised health-wise. Concomitant medications included amlodipine, atorvastatin, losartan, sotalol, terazosin, and warfarin. On 08Mar2021, the patient was weak and feeling more unwell every day. On 09Mar2021, the patient collapse while he was in the shower. The wife of the patient reported regarding some possible side effects for her husband. He had been weak but on 09Mar2021, he collapse while he was in the shower and that was pretty dramatic but he has been getting weaker and weaker and feeling more unwell every day since 08Mar2021; at this point he was literally appointed for the second shot on the 26Mar2021, so wife was asking if it was advisable being he had what maybe side effects between the vaccine and his other health conditions, that he should take his second shot. On an unspecified date, the patient was shrinking now. The patient was due date for second shot on 26Mar2021. The reporter stated that the lot was EN6203, and it could be ENU203, the handwriting was very bad, and she don't know if it was U or 6. Outcome of events was unknown. Information about Lot/Batch number is requested.

Shingles and Hospitalization within 30 days of vaccination. 2/18/21 PCP ordered outpt wound for shingles and unstageable decubitis ulcer (unknown onset date of shingles). Seen in ER on 2/19 and admitted discharged to rehab unit on 2/23/21. reported 1-2 week history of generalized weakness and frequent falls, poor oral intake and shingles. 2/19/21 pt c/o heart racing and irregular. Found to be in Afib with RVR. 2nd dose of Pfizer given 3/19/2021 went to ER 3/24 for pneumonia.

respiratory arrest, cardiac arrest Narrative: Patient died 1 day after receiving 2nd dose of COVID vaccine in his bed at home. Paramedics arrived but were not able to resuscitate.

6 days after receiving the first dose of Pfizer Covid-19 vaccine, he developed severe disequilibrium to the point that he had severe difficulty sitting up and ambulating. The disequilibrium was severe for twelve days but then seemed to be largely resolved. The second Pfizer Covid -19 vaccine was received on 02/06/2021 (lot EN5318) and the severe disequilibrium began again February 12. complete evaluation with CT head, abdomen and pelvis, chest X-ray, lab , EKG and echocardiogram showed no explanation for symptoms. The second round of severe disequilibrium resolved by February 25.

Pulmonary Embolism in right lung; This is a spontaneous report from a contactable consumer (patient). A 92-year-old male patient received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection, Batch/Lot Number: EL9267), via an unspecified route of administration, administered in right arm on 16Feb2021 at 12:45 PM at the age of 92-years-old as single dose for COVID-19 immunization. Facility type vaccine was reported as Other. The patient had no other vaccine in four weeks. The patient's medical history included known allergies to penicillin and sulfa drugs. Concomitant medications included fluoxetine, cyanocobalamin (B12-VITAMIN), and fish oil (OMEGA 3); all taken for unspecified indications, start and stop dates were not reported (reported as other medications in two weeks). The patient previously took potassium iodate and experienced allergies. The patient previously received the first dose of BNT162B2 in the right arm on 26Jan2021 at 12:45 PM (lot number: EL9261) at the age of 92-years-old for COVID-19 immunization. The patient experienced pulmonary embolism in right lung on 07Mar2021 at 09:00 AM. The event resulted in emergency room/department or urgent care, hospitalization, life threatening illness (immediate risk of death from the event). The patient was hospitalized for pulmonary embolism in right lung for 2 days in 2021. The patient received treatment for the event which included heparin. The patient had no COVID prior the vaccination and was not tested for COVID post vaccination. The outcome of the event was recovering.

Patient was a well and active 92 year old man, who walked 2 miles daily with a walker. He received Covid vaccine dose 1 on 11 Jan. On or before 30 Jan, he noted pains in one leg while walking. Newly dilated veins on the lower leg were noted. On feb 2 a doppler US revealed a superficial saphenous vein venous thrombosis, also new onset A flutter. Aspirin begun. On Feb 5 he woke with a cold foot (same side) and was found to have an arterial thrombus from SFA through distal posterial tibial. He underwent emergency thrombectomy, went to rehab for recovery, on Feb 23 suffered intracranial hemorrhage and died on Mar 10.

This 92 year old white male received the Covid shot on 2/23/21 and went to the ED and admitted on 5/3/21 and again to ED and admitted on 5/5/21 with the following diagnoses listed below. I21.4 - NSTEMI (non-ST elevated myocardial infarction) (CMS/HCC) CHEST PAIN

PER SPOUSE, HE HAD A CUT ON HIS LEG THAT DID NOT STOP BLEEDING. THEY WENT TO CLINIC TO GET IT CAUTERIZED. DAY LATER HIS BODY HAD MULTIPLE BRUISES, THEN HE WAS EVEN BLEEDING FROM HIS PENIS. AT HOSPITAL THEY TOLD HIM HE HAD LOW PLATELETS AND WAS BLEEDING OUT. HE WENT INTO HOSPICE AND PASSED AWAY ON 5/8/2021

abdominal pain; nausea; high blood pressure; This is a spontaneous report from a contactable consumer. A 93-year-old male patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, lot number: EL0140), via an unspecified route of administration on 22Dec2020 at a single dose for COVID-19 immunization. Medical history included diabetic and irritable bowel. The patient's concomitant medications were not reported. The patient received the COVID vaccine and had abdominal pain, nausea and high blood pressure within 12 to 18 hours of vaccine received. The events lead to nursing home to emergency room and admitted to hospital. The patient was hospitalized due to events since 23Dec2020. Outcome of the events was recovering.

Reporting per Pfizer that patient tested positive for COVID post-vaccination (1/21/2021) and was hospitalized (1/24/2021). Patient received Bamlanivimab treatment 1/22/2021, 2nd dose will be deferred 90 days per PCP. Patient admitted for hypoxia, improved SPO2 to >95% on room air, and was discharged back to ALF 1/25/2021.

general malaise , Fatigue, poor interest in activities , hypoactivity, pulmonary embolism Narrative: Patient transferred to ER for evaluation. Physician at facility reported marked deterioration, hypoactivity and slow mentation s/p COVID vaccine second dose 1/8/21. Cough also reported x 1 week. Patient evaluated at ER on 1/20/21 and admitted to internal medicine ward with diagnosis impression pulmonary emboli, aspiration pneumonia and urinary tract infection.

death Narrative: 92 yo male seen in clinic on 12/30/2020 for transfusion, hbg 6.9. PMH includes HLD, CKD, myelodysplastic syndrome, DM, prostate cancer, HTN. Pt also received COVID19 Pfizer vaccine the same day. The patient denied any prior severereaction to this vaccine or its components. Post-transfusion, patient had a mechanical fall (per patient he was seated and used the cane to help him stand. However the cane slipped on the floor causing the patient to fall, patient hit his head and injured his right hip, no loss of consciousness at the time). Rapid response team was called and patient was admitted to the ED. Pt was found to have subcapital right femoral neck fracture, scalp contusion, and TBI (per ED provider's note). Ortho evaluated and said patient wasn't a surgical candidate. During his hospitalization, patient tested positive for COVID19 on 1/12/2021, pt was asymptomatic at the time. On 1/13/2021, pt exhibited mild URI symptoms, no respiratory distress. He was started on cetirizine, Montelukast, albuterol, and inhaled steroids to manage his symptoms. Dexamethasone was started on 1/14/2021. Chest Xray was ordered on 1/17/2021, pt's respiratory was slowly getting worse, resting O2 sats were in the high 80s and low 90s with IS. On 1/18/2021, CXR shows patchy bilateral airspace opacities suspious for pneumonia of bacterial or viral etiology. Pt was started on remdesivir 01/18/2021 (5 doses, from 1/18-1/22/2021). Pt required 5-6 LPM of oxygen at rest. Pt was then transferred to the ICU. His oxygen demand continued to increase and his condition worsened. On 2/14/2021, pt started to desat into the 70s on max high flow. Patient/family agree to comfort care. Medical cause of death was listed as "acute hypoxic respiratory failure due to COVID19." Patient expired 1/24/2021.

right arm swelling immediately after injection. followed by bilateral lower leg edema, chills and body aches that continued daily at 2 weeks post immunization admin 2/4/21 treated with dexamethasone 6mg PO x 7 days- this resolved his s/s 2/13/21 patient passed away at facility

Patient received his second dose of the Pfizer vaccine. He was accompanied by his daughter. Per daughter prior to receiving his vaccine he was his "normal" self. He was sitting in a chair next to the vaccinator. He did walk in with a walker and minimal assistance from his daughter. He did have a gait belt on around his waist. When I came to patient he was looking straight ahead with his left eye open - right eye s/p surgery to his right eye per daughter. He did not respond to questions asked. His daughter stated mentally he is normally intact. His pulse was faint but palpable. His color was pale with slight dusky skin to hands. 911 was called. Undetectable blood pressure initially with his faint pulse. Initially his heart rate was 105. He was shallow breathing. BP was undetectable sitting - with oxygenation low 80's on room air. He was lifted to a bed/cart with legs elevated. He was given supplemental oxygen. After laying down with legs up he started to look around. He was able to tell me his name and respond to questions. His blood pressure was 117/68 with heart rate 55 and oxygenation on 6L nasal cannula 87-88%. Patient's daughter stated that patient was recently at hospital with low blood pressure and questionable seizure activity. No obvious seizure activity noted today. Parametics - updated with patient history and events. Blood sugar checked at 183. Patient neurologically improved with ability to state name, his daughters name and his age. No injury noted. Dr phoned and updated on patient condition and events. Patient transported without injury on oxygen. Two daughters with patient to emergency room. Pt being evaluated by cardio on admission for sycope/possible seizure. Still admitted

Patient received first dose of vaccine on 1/7/21 at a community Public Health clinic. On 1/29/21 he received a second dose at the community Public Health clinic. On 2/5/21, the patient presented to the ED with complaints of shortness of breath worsening over the last 2 weeks. Patient reported that he had decreased exercise capacity and increased coughing with sputum production intermittently. Patient reported that he had been feeling chilled, but no fevers. Patient was admitted and treated with Decadron and Remdesivir. Patient experienced increased oxygen requirement. Patient was a DNI and did not want to be on life support. After discussion with the patient and family, patient was moved to comfort care. passed away on 2/11/21.

hospitalized with extensive bilateral pulmonary emboli and right leg deep vein thrombosis after 1st vaccine dose. Required high-flow nasal canula for oxygen support. ultimately discharged on hospice

Disorientated; in a lot of pain in his chest and rib area; in a lot of pain in his chest and rib area; hurt to breathe and move; shaken up; Short of breath/It hurt to breathe; Concomitant medication:ongoing prednisone for immunotherapy; Concomitant medication:ongoing prednisone for immunotherapy; This is a spontaneous report from a contactable nurse. A 93-year-old male patient (reporter's father) received first does of BNT162B2 (Lot#: EN5318), via intramuscular on 28Jan2021 10:00 at single dose for COVID-19 immunization. Medical history included ongoing prostate cancer metastatic diagnosed a few years ago and immunotherapy. Concomitant medication included ongoing abiraterone acetate (ZYTIGA) at 1g, once a day for prostate cancer and ongoing prednisone at 5 mg, tablet, twice a day, by mouth for immunotherapy. The caller stated she is reporting a reaction her father had to Pfizer's COVID-19 vaccine. The patient experienced disorientated, in a lot of pain in his chest and rib area, hurt to breathe and move and short of breath/it hurt to breathe on 29Jan2021. The reporter seriousness for the events was medically significant. The events didn't require a visit to emergency room or physician office. The patient did go to urgent care. The caller explained her father became disoriented. He received the first vaccine on 28Jan2021. The next day, her father began to move his car around 12 pm and he became disoriented and stated he wasn't going to drive. Caller stated they were not aware of this disorientation until Friday, 29Jan2021. Her father was not sleeping and was up the night before because he was in a lot of pain in his chest and rib area. It hurt to breathe. He was short of breath. It hurt to move. Caller clarified further her woke up feeling so bad he thought he was going downhill. He thought his cancer got worse over night. He told the caller's brother after he became so disorientated that he was no longer going to drive because he was so shaken up. He was taken to urgent care on Friday, 29Jan2021. He was prescribed Naproxen, 500 mg Friday evening and he slept all night for the first night in years. He usually gets up in the middle of the night to use the bathroom. He woke up on Saturday morning, 30Jan2021, and he was feeling 100% better. He recovered completely. He was up moving around and in no pain. Caller verified she has no NDC, Lot number and expiry date for the Naproxen her father was prescribed. She didn't see any of that written on the discharge papers, that may be with the pharmacy. She wanted to put a chest x-ray was done. He has Metastatic Prostate Cancer and the pain was coming from the lesions on his lung and rib. Caller explained the Chest X-Ray showed the mets (metastasis) but no new lesions, no infiltrates or anything. It showed nothing related to the COVID-19 vaccine.The patient underwent lab tests and procedures which included Chest X-ray: showed the mets (metastasis) but no new lesions, no infiltrates or anything on 29Jan2021 and EKG: essentially normal on 29Jan2021. The outcome of the events disorientated, in a lot of pain in his chest and rib area, hurt to breathe, shaken up and move and short of breath/it hurt to breathe was recovered on 30Jan2021. The reporter's assessment for all the events was related.; Sender's Comments: Based on the compatible time association, the contribution of suspect vaccine BNT162B2 to all events disorientation, chest pain, musculoskeletal chest pain, movement disorder, shaking, and shortness of breath cannot be excluded. The ongoing prostate cancer metastatic status and immunotherapy may be major cofounders. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory Authorities, Ethics Committees and Investigators, as appropriate.

Low platelets, thrombocytopenia, bleeding from mouth, large bruising, purpura, petechiae, rash of pinpoint-sized reddish-purple spots on lower legs. Treated with at least 2x2 units of platelets, IVIG for several days (at least), diagnosed as ITP, immune thrombocytopenia. Developed aspirational pneumonia in hospital. Admitted with platelets at 1x10^9/L; discharged on day 5 with 79x10^9/L. Patient had ITP 10 years earlier and was recovered from it.

K62.89 - Rectal pain R42 - Dizziness R41.0 - Delirium R55 - Syncope R77.8 - Elevated troponin M25.552 - Left hip pain Z86.2 - Hx of thrombocytopenia M79.662 - Pain in left lower leg

Cause of death is believed to be a fatal arrhythmia resulting from advanced old age and aggravated by sepsis due to COVID-19 infection along with gastroenteritis. The death was natural and not unexpected. Tobacco is not believed to have contributed to t

Received 2nd shot on April 14. He was functioning normally until he woke up on April 25. Symptoms were chest pain, trouble breathing, lethargic, very pale, cold to the touch, vomiting with blood in vomit. PT was taken to the ER where he passed away later that night.

Systemic: Blood Disorder (diagnosed by MD)-Severe, Additional Details: Patient passed away on 4/23/21 and had blood clots throughout body. Patient did not have any other symptoms that were reported. Patients family requested a VAERS report be submitted.

Developed severe nosebleed 23 hours and 30 minutes after receiving vaccine. Bleeding time OK but platelet count on the low side (165,000)

N17.9 - Acute kidney failure, unspecified D69.6 - Thrombocytopenia, unspecified K92.2 - Acute lower GI bleeding K92.2 - GI bleed

ED to Hosp-Admission Discharged 3/31/2021 - 4/12/2021 (12 days) Last attending ? Treatment team Pneumonia due to COVID-19 virus Principal problem Date: 4/12/2021 DOB: 1/13/1928 Admission Date: 3/31/2021 MRN: 000452141 Length of stay: 12 Days Admission diagnosis: POA * (Principal) Pneumonia due to COVID-19 virus Yes HPI: Patient is an 93 y.o. male presenting to ED on 3/31/21 with worsening shortness of breath with fever occasional cough, and fatigue. He just received his second dose of his covid vaccination 3//26. Hospital Course: Patient was admitted to receive treatment for COVID 19 infection. On presentation he was hypoxic requiring supplemental oxygen, he was in Afib RVR. He received experimental treatment with plasma, remdesivir, and dexamethasone. He had a AKI in setting of infection that improved, and his lasix was added back. He has CKD3, would recommend re-check cr in 3 days after discharge. He did develop acute urinary retention that required a foley to be placed. Void trail in hospital was unsuccessful, suspect relatedd to weakness/poor endurance. Can considner ongoing voiding trails as his health improves and or outpatient urology consult. Paroxysmal Afib in the setting of viral infection, with fluids and increasing metoprolol rates improved. Once he recovers from Afib can consider MCOT to evaluate Afib burden, continue ASA Covid pneumonia Acute hypoxic respiratory failure, from COVID Pneumonia Received convalescent plasma Received Dexamethasone 10 day course Completed remdesivir 5-day course on 4/4/21 Oxygen Requirement continues at 2 L nasal cannula Inflammatory markers trended down He was vaccinated SECOND INJECTION on 3/26. Acute kidney injury on chronic kidney disease stage IV Creatinine improved with IVF did upwardly trend again likley from acute urine retention Cautiously watch Cr while on Lasix, consider checking CR/BUN in 3 days Monitor creatinine, avoid nephrotoxins Discharged with foley, continue Flomax. Consider voiding trails at SNF and/or urology consult Paroxysmal atrial fibrillation -new onset Metoprolol tartrate increased during hospitalization patient will benefit from outpatient event monitor to determine A. fib burden once he recovers from Covid, to be arranged by PCP continue aspirin

Had no immediate issues with the vaccine. He had returned from the hospital on 12/21 and had some concerns about his weight which were shared with his physician on 1/4/21. On 1/5/21 had a visit with his cardiologist for a pacemaker check. On 1/8/21 staff were called to his room, he was on the floor, bluish skin color. No vital signs found, no heart rhythm heard at 2200.

This is a 94-year-old male who is brought in by ambulance after being found on the floor with unknown downtime. He was in asystole upon EMS arrival. He remains in asystole. No advanced airway is in place. The patient is getting compressions from Lucas device upon arrival. It was reported that he was last talked to by family at 2 PM. The patient got his SARS-CoV-2 vaccination this morning. The patient is evaluated emergently. CPR was ongoing with 3 rounds of epinephrine given. The patient remains in asystole. He has rigor mortis. The patient's pupils are fixed and dilated. The patient has compressions paused and ultrasound is used to evaluate for cardiac activity. None is detected. The patient has no electrical activity on monitor. The patient's time of death is 2113.

Patient was discharged after receiving vaccine. patient presented with symptomatic AS to the hospital. Family declined intervention. Received vaccine prior to discharge. His wife reported that he was sluggish/unresponsive in the evening that self-resolved. Declined ED evaluation. Currently only experiencing dizziness. Given severity of underlying cardiac disease, unclear if vaccine was cause of symptoms.

2/12/2021 @ 5:30 started to develop rapid heartbeat, high pulse of 175, called 911, transported to hospital, treated by shocking(incorrect term) kept overnight discharged 2/13 afternoon. Next incident was 2/15 @ 5:00am same series of events and is still currently at hospital still being treated as of 2/16/21 afternoon.

Pt with underlying COPD and chronic respiratory failure requiring BIPAP. Pt had cardiopulmonary arrest on 2/24/21 and died as a result. Pt was overall palliative-focused plan of care.

started him on his oxygen; O2 went from 85 to 98; bp 155; notably shuffled; became non-responsive; looks like he is having a stroke; This is a spontaneous report from a contactable consumer (patient's daughter). A 94-year-old male patient received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE; lot number and expiry date: unknown), via an unspecified route of administration on 25Feb2021 13:45 (at 94-year-old) at single dose (Arm Right) for COVID-19 immunization. Vaccination facility type is clinic. Medical history included congestive heart failure, early stages dementia. The patient's concomitant medications were not reported. The patient previously took first dose of bnt162b2 on 04Feb2021 (at 93-year-old) on right arm for COVID-19 immunization. The patient had no covid prior vaccination. Patient has no known allergies. The patient (father) seemed to be doing fine until 19:45 on 26Feb2021 roughly 30 hours after vaccination. He has early stages dementia, so if he was feeling ill he didn't report anything, and they didn't notice anything. He got up from the table, notably shuffled the 10 feet to the bathroom, sat down on the toilet before we could "pull down his pants", and then became non-responsive. The reporter said to her son it looks like he is having a stroke. They got him onto the floor. started him on his oxygen concentrator (usually used only at night), O2 went from 85 to 98; bp 155 from an unspecified date. after a while he came to. he is dnr, dni, so they didn't call an ambulance. Eventually they got him up. no signs of stroke. He does have congestive heart failure. This has never happened before, and he has no history of falling. Daughter was reporting the next morning. He has not yet been awake since this occurred. it is now 8am 27Feb2021. Covid was not tested post vaccination. The outcome of the event o2 went from 85 to 98 was recovered, while for other events was unknown. Information on the lot/batch number has been requested.

Pt had long complicated course spanning almost a month. He was initially admitted for right intertrochanteric hip fracture (following a fall at home) for which he required surgery. Also had bacterial pneumonia and received Zosyn. He was close to discharge at 1 point but then had Covid testing done which came back positive. He gradually worsened from there with acute hypoxic respiratory failure and very poor oral intake. He had multiple episode of hypoglycemia and required D5. He was made care only but improved on his own and was back on medical Mx. It did not last long and he again became very tachypnic in 60s and hypoglycemic. He was made care again. Pt passed away peacefully with his daughter at the bedside on 3/11/21 at 11 AM Causes of Death: 1. Cardiopulmonary arrest due to reason #2 2. Failure to thrive due to reason #3 3. Old age and COVID-19 No autopsy performed.

Increased Fatigue, Bradycardia, unable to arouse pt. Sent to emergency room, admitted for observation and testing.

OX SATURATION AS LOW AS 74, TEMPERATURE OF 100.5, DYPHORETIC, SHAKING, HOT TO TOUCH, PALE, FEELS TERRIBLE COUGHING

Had a stroke 3 days after round one of Covid vaccine and subsequently died the next week due to complications of stroke. Upon admission to hospital, was in afib.

L hand edema, hematoma which burst and caused bleeding sending pt to the ER for pressure dressing and 2 stitches. L hand and arm progressively got more edematous and bruised looking (severely black/blue/purple) and the hand continued to bleed and swell on 2/6/21. Severe arterial and venous issues and apparent blood clots. On 2/7/21 there were also lumps noted on left inner thigh. Pt. stopped eating or drinking on 2/8/21 and expired on 2/12/21.

Patient continued to deteriorate after second dose of vaccine with progressive weakness and shortness of breath. When he presented to the emergency room he had new onset cardiomegaly and heart failure. Patient also developed new onset atrial flutter but had bradycardia due to AV heart block.

Came in ED due to a fall and rhabdo. Found to have NSTEMI Monitored symptoms. started on plavix and switched statin to atorvastatin and metoprolol tartrate to succinate discharged home

EM reported to emergency department on 3/29 with complaints of abdomianl pain, dirrhea, body aches , fatigue, weakness, hypoxia, headache and shortness of breath Admitted to Hospital 3/29 and discharged 4/1

PT REPORTED TO EMERGENCY DEPARTMENT WITH COMPLAINTS OF WEAKNESS AND FALL 2/15/21. PATIENT STATES THAT HE HAS BEEN FEELING WEAK AND TODAY IT SEEMS WORSE. HE REPORTS ATTEMPTING TO AMBULATE WHEN HIS LEGS GAVE OUT. HE STATES THAT HE DID NOT TRULY FALL BUT WAS ABLE TO LOWER HIMSELF TO THE GROUND. HE WAS UNABLE TO GET UP AND THEREFORE CALLED EMS. EMS WERE ABLE TO HELP PATIENT UP AND AMBULATING. EMS NOTED URINARY BAG HAD GROSS HEMATURIA. PT REPORTS BLOODY URINARY OUTPUT THE PREVIOUS NIGHT. PATIENT COMPLAINS OF PENILE PAIN. NO RECENT ILLNESS INCLUDING FEVERS, URI SYMPTOMS, VOMITING OR DIARRHEA. ASSESSMENT UPON ADMIT: *CONTINUATION SEE BELOW PT REPORTED TO EMERGENCY DEPARTMENT WITH COMPLAINTS OF WEAKNESS AND FALL 2/15/21. PATIENT STATES THAT HE HAS BEEN FEELING WEAK AND TODAY IT SEEMS WORSE. HE REPORTS ATTEMPTING TO AMBULATE WHEN HIS LEGS GAVE OUT. HE STATES THAT HE DID NOT TRULY FALL BUT WAS ABLE TO LOWER HIMSELF TO THE GROUND. HE WAS UNABLE TO GET UP AND THEREFORE CALLED EMS. EMS WERE ABLE TO HELP PATIENT UP AND AMBULATING. EMS NOTED URINARY BAG HAD GROSS HEMATURIA. PT REPORTS BLOODY URINARY OUTPUT THE PREVIOUS NIGHT. PATIENT COMPLAINS OF PENILE PAIN. NO RECENT ILLNESS INCLUDING FEVERS, URI SYMPTOMS, VOMITING OR DIARRHEA. ASSESSMENT UPON ADMIT: THROMBOCYTOPENIA (PRESUMED ITP, CAUSE? VACCINE?), DEXAMETHASONE 20MG PO DAILY. AMINOCAPROIC ACID 5GM IVPB X1 DOSE, 1 UNIT FFP, 2 UNITS PLTS PHERESED

Vaccine 1/10, 1/31. Admit 3/28. COVID PNA w/hypoxia. Treated w/dexa and zinc. UTD acute or "old" Covid infection per MD note. Still in hospital, palliative care to consult. Pending possible facility placement.

Death Narrative: Patient was not previously Covid positive and did not have any predisposing factors(PMH, allergies, etc.) for experiencing an adverse drug event. The ADR did not occur at the time of the administration of the vaccine nor was there an ADR that occurred between the observation period and the date of death. Patient was 95 and admitted to ED on 2/26/21 with leg edema and diarrhea. Had periods of bradycardia in the 40s during admission. Diagnosis was heart failure exacerbation which caused a significant decline in his condition resulting in eventual palliative care before his death. Notable comorbidities include CAD s/p cabg, T2DM, HFrEF, CKD, HTN, recurrent UTIs.

COVID-19; Chronic heart failure with preserved ejection fraction; Elevated brain natriuretic peptide (BNP) level; Fatigue; Hypokalemia; Hyponatremia; Need for vaccination

Early in the shift on January 31 resident was noticed to be more tired than usual and was not eating well. Lung sounds were crackly and resident was found to be hypotensive. He was evaluated in emergency department. He was diagnosed with pneumonia. Received a loading dose of antibiotic and returned to facility.

5/3/21 this gentleman reported several days of Left lower leg pain. Ultrasound completed positive for left lower leg DVT. Pt was on chronic Coumadin therapy at that time with therapeutic PT/INR 2.7. Symptoms progressed and ongoing despite initiation of Eliquis. On 6/8/21 he underwent placement of IVC filter to protect from further clotting injury.

Major Complex Seizure with post-ictal period of 2 hours, occurring 3 hours after receiving injection. 16 days later on March 6, 2021 was unable to void, sustained breathing difficulty with peripheral edema. Received diuretic from Nurse,. Indwelling Catheter was inserted. On day 17, after receiving Corvid Vaccine, DECEASED on March 7, 2021 at home. Sustained Complex Seizure 6 hours prior. Death Certificate ruling Cause of Death as Cardiac Arrhythmias.

Patient was brought into the ER with weakness, confusion and decreased appetite for days after testing positive for COVID19 on 2/6. Patient's wife had a fall on 2/2, patient helped his wife and again had recurrent fall and finally took to hospital on 2/5 where she was tested positive for COVID 19 and passed away on 2/5. Patient received his first dose of COVID-19 vaccine on 1/29/2021. Patient's daughter was concerned about patient's confusion, breathing and decreased energy levels and recommended to come to hospital for evaluation. Daughter report that she noticed mild fever, cough and some diarrhea on 2/6 when she came to check on him after her mother tested positive on 2/5. She thinks he might have symptoms 1-2

This is a 98y.o. male with past medical history of s/p covid on 4/20/21 and treated with antibodies and received pfizer x2, dementia, aortic aneurysm, MI s/p AICD, a fib hypothyroidism, presents to ED via EMS. Patient is alert and oriented to person and place but not time. He does not know why he is at the hospital or who called 911 or why they called. Most of history was obtained from son. He states that this morning the facility noticed that he was more confused than usual and that he seemed short of breath. When they checked his vitals his blood pressure was low an his oxygen saturation was low. Per EMS report he was short of breath while walking to the common area and his fingers turned blue. EMS sheet 104/54 and spo2 94% on room air. Patient states that he has no complaints. He denies any shortness of breath currently, chest pain, abdominal pain, diarrhea, melena, hematochezia, palpitations. He does admit to some back pain when laying too long. Son stated that he is supposed to see his cardiologist Dr. for his defibrillator having "weird signals". Son states that he usually aspirates once a meal when asked if patient has been coughing at all.

Patient received COVID-19 Vaccination at about 11am. About 1.5 hours later he stated did not feel well and o2 sats had dropped to 74%. The facility employees alerted the vaccination staff as they were still in the building. Vaccination team directed staff to call 9-1-1, but patient is on hospice so they called the hospice nurse instead. Vaccination team had staff lay patient back down in bed and raise feet above heart. o2 stats rose back up to 88%. Hospice nurse arrived and sat with patient. Patient's physician was contacted. Patient had returned to baseline within 3 hours and 15 minutes of vaccination.

Decedent had unwitnessed fall out of wheelchair 1/25/21 around 9:43am, denied head strike, pain, discomfort. Around 10:02pm, 1/25/21, decedent noted to have slurred speech and fluctuating HR, transported to Hospital and made cmo.

NA- patient refused second dose of vaccine - Patient condition at time of death Chronic Conditions Renal failure Advanced age 100 y/o Cardiopulmonary arrest secondary to Covid 19

Adverse reaction to the vaccine started with variable weakness beginning 1/29/2021. On 1/30/21 around 8:30pm, he needed assistance in the bathroom related to weakness and had what was later identified as a stroke with left side weakness and slurred speech. In accordance with his wishes, he had care at home. Due to his advanced age and frailty, a CT scan was not pursued. The 325 mg of aspirin that he was previously taking daily was discontinued. After the stroke, he needed total care. Hospice was established at home. Nursing assistant care was delivered by daughter. Death followed 9 days later (2/9/2021).

Patient is 102 years old history of hypertension hypothyroidism, patient presenting with altered mental status, hemoglobin of 4.6 with creatinine of 2.53, patient has lactic acidosis, anion gap metabolic acidosis. Stool Hemoccult is positive, platelet count of 23,000 noted. Patient is awake but confused, patient's son is by the bedside.Patient has diffuse oozing from multiple skin wounds,Patient has received 2 units of blood along with 2 units of platelets and 2 units of FFP. Fibrinogin of 209. Hematology service recommended starting dexamethasone for suspected ITP. Patient is a PMH of  spontaneous subdural > 20 years ago, surgically evacuated, HTN, Hypothyroidism ,pre-diabetes who presented to the ED with CC of AMS and slurred speech x 1 day. History obtained from son at bedside and chart review. At baseline patient is reportedly very independent and able to ambulate in the home without assistive devices. He handles his own ADLs. Patient reportedly received his 2nd dose of the COVID vaccine on Monday and since then has been experiencing fatigue and generalized weakness, in addition to decreased appetite. AMS started yesterday. He reportedly fell out of bed last night around 2 AM and family found him at 7 AM on the floor. Denied loss of consciousness. He was evaluated by Stroke team, CT of the head was un-revealing for an acute process and stable chronic changes, and CTA revealed some mild intracranial stenoses, Stroke team felt was unlikely to be an acute stroke. He was found to have Hb 4.6 on admission. Platelets were 23, He was transfused 1 unit of blood and 1 unit of platelets. Hematology was consulted and recommended dexamethasone 20 mg daily for 3 days. Rectal exam was done and he was found to be Guaiac positive was started on Protonix 40 BID.

Pt received his 2nd pfizer covid 19 vaccine on March 11 (the lot number was not written on the card unfortunately) and was hospitalized from 5/21-6/4 with new onset profound hypotension and new onset atrial fibrillation with a bradycardic rate.,requiring ICU admission and pressor support. He presented with a fall and was found to be profoundly hypotensive. Sepsis was ruled out and the cause was unclear. He was eventually started on midodrine . He did not require any rate controlling medication. His daughter did not want anticoagulation ordered due to risk outweighing benefit. He was diagnosed with new autonomic dysfunction and new atrial fibrillation and discharged home on 6/4/21

Patient presented to the ED and was subsequently hospitalized with CVA. This is within 6 weeks of receiving COVID vaccination.