Pfizer

Morning after vaccine the patient developed fever, myalgias and then developed abdominal pain and vomiting. Presented to emergency department where he was noted to have elevated inflammatory markers, gallbladder thickening, and decreased EF in the 40s. Patient met criteria for MIS-C and was treated with IVIG and steroids. Case was reported to a federal agency.

Patient is currently being treated for Guillain Barre syndrome, with symptoms of bilateral feet weakness that then extended up to his thighs, leading to difficulty walking and falling with attempts to stand. He has had no loss of sensation and also states that he had sensation of a full bladder but could not urinate and did experience urinary incontinence.

Fever, vomiting, rash, hepatitis with direct hyperbilirubinemia, acute kidney injury (resolving) Amoxicillin for strep throat, IVIG for possible Kawasaki disease,

Patient received his first dose of Pfizer Covid-19 vaccine on 5/15/2021 and the second dose of Pfizer Covid-19 vaccine on 6/5/2021. After an abrupt onset of mid thoracic back pain and leg weakness on 6/16/2021, the patient rested for the night. In the morning, he was unable to walk, characterized by dragging his feet and falling o the ground. He was unable to void. Mother sought care for him at the Emergency room on 6/17/2021. In the ER, he had an MRI scan of his spine which showed no significant central canal foraminal stennosis. He was catheterized and had urinary residual of 600ml after an episode of urinary incontinence. Neurology at the Clinic was consulted and patient was transferr

Situation: 14yo male came in for first dose Pfizer vaccine. Within 5 mins after receiving vaccine, patient had a seizure for approximately 1 minute. During seizure, patient was incontinent of urine. RN was able to get to patient's side before he fell. Background: Patient did not alert vaccinator or RNs that he had a history of seizure. Mom informed staff after the event that he had a febrile seizure when he was a young child. She did not disclose what age he was at the time of the previous seizure. Assessment: RN observed patient in an active seizure for 1 minute in which his body contracted out and his eyes rolled back. She was at his side to prevent him from falling. He was placed on a gurney and moved to room 6 for closer observation for 30 mins. Pfizer vaccine administered on 5/22/21 at 12:52PM 1255 vitals ? 121/64(83), 97.3F 1257 vitals ? 122/75(90) 1311 vitals ? 116/76, HR 68, 100% O2 1318 vitals ? 112/75, HR 68, 100% O2 1325 vitals ? 111/61, HR 68, 99% O2 Recommendation: MD on call, was called and notified of the event. Her recommendation was for the patient to go to the ED for evaluation and labs. RN called the ED to notify them of the patients intended arrival. The mom agreed to take the patient to ED for further evaluation. The patient was taken out via wheelchair.

Urinating blood. Took to the doctor on Wednesday 5/19/21, they confirmed that he has blood in his urine, and so far, they don't know what is causing it. All tests for infection, etc., with his urinalysis came back negative. has never urinated blood in his entire life. We took him in on Friday May 14th to get his 1st COVID shot (Pfizer), less than 3 days later he started peeing blood, and he still is, every single day since.

The patient was seen for well visit on 28May2021 and noted to have significant hypertension above normal limits for age (151/95). This was repeated and confirmed on manual reading. The patient was asymptomatic, and record review was noted to have had normal BPs for his entire life prior to this. Over the following week the family monitored home BPs and continued to be in hypertensive range (SBP 140s-130s) but slowly trending down over the next week.

Day 2 chest hurt to breathe in deeply gave Tylenol subsided 2 days later. Had UTI symptoms on day 3 gave cranberry juice also subsided 2 days later symptoms were frequent urination, pain and burning during and after, hurt when laying down. Never had any type of infection in urinary tract before. All symptoms were very treatable just didn't know he would experience these. All other symptoms he went through were expected. Fever never went above 101 and he had a temp and flu symptoms for 3 days with swelling under his arm

He received the second dose of his covid vaccine on 6/7, began to experience sharp chest pain with exertion on 6/11. Pain is central, to the right of the sternum, without radiation. The pain then became more dull, aching, and has been interfering with his sleep. It does seem to be worse when he is thinking about it, better when he is distracted. He went to basketball tryouts 6/15 and the pain has been more frequent since that episode of strenuous exercise. He has not taken anything for the pain. He also notes more frequent fatigue. He denies any prior covid infection. No recent illness or sick contacts. Denies cough, fever, GI upset, diarrhea. He is going to school in-person, they all wear masks.

Pt mother called and stated that pt is vomiting and has a fever of 101.9 pt mother state that pt received the second dose of COVID vaccine on 6/29/21 and now he is having these symptoms. Pt mother state that pt had these symptoms before with the first dose however they resolved on there own. Pt is now complaining of chest pain is unable to take a deep breath because it causes him pain. Patient Has not attempted treatment at home. CHIEF COMPLAINT: VOMITING (one episode of vomiting this morning) and FEVER (fever started on Wednesday) Assessment/Plan DIAGNOSIS at time of disposition: 1. Acute myocarditis, unspecified myocarditis type 2. Acute chest pain 3. COVID-19 virus not detected Patient presents with chest pain 2 days after 2nd COVID-19 vaccine. Labs were obtained and his troponin is elevated to 122 and his CRP is also elevated. I discussed case with ID, recommended admitting to Cardiology for workup for myocarditis. 14 y/o previously healthy male who presented to hospital after onset of chest pain, fever, chills, and vomiting this morning. Found to have elevated troponin and mild ST changes on EKG. Patient recently received 2nd Pfizer-BioNTech COVID vaccine on 6/29. Admitted for close monitoring and further work up of suspected myopericarditis following COVID vaccination.

6/29: usual state of health until Saturday 6/26/21 when he began to experience chest pain. Due to the pain persisting for 2 days, parents brought him to the ED. He describes the pain as "pounding" and lasting for up to "half an hour". He reports no recent illnesses or fevers, but does note that he received the second dose of the Pfizer vaccine 4 days ago (6/25/2021). In the ED he had a CXR, EKG and screening labs which showed elevated troponin. Secondary to this the decision was made to admit patient for continued evaluation and management of possible myocarditis. troponin up to 0.6 at 2100. SARS-CoV-2 PCR is negative. 6/30: IVIG administered overnight due to increasing troponin. troponin now 0.36. chest pain resolved. 7/1: troponin trending down to 0.06. No complaints of chest pain. discharged home.

typical Guillain-Barre syndrome; he could not walk; he cannot play any sport because he cant run/ no control from his waist down; he needed a catheter ,he was not able to pee or poop; he needed a catheter ,he was not able to pee or poop; This is a spontaneous report from a contactable consumer (parent). A 14-years-old male patient received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection; Batch/Lot Number: EW0179; Expiration Date: 31Aug2021; NDC number and UPC number: unknown) via intramuscular on 15May2021 (at the age of 14-years-old) in left arm (shoulder) as a DOSE 1, SINGLE for covid-19 immunization and second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, solution for injection; Batch/Lot Number: EW0182; Expiration Date: 31Aug2021; NDC number and UPC number: unknown) via intramuscular on 05Jun2021 (at the age of 14-years-old) in left arm (shoulder) as DOSE 2, SINGLE for covid-19 immunization. Medical history included papilloma viral infection from 06May2021 to 06May2021 and bowel movement irregularity from an unknown date and unknown if ongoing. The report was not related to a study or programme. Prior vaccinations (within 4 weeks) included HPV (human papilloma virus) vaccine on 06May2021. Concomitant medication included macrogol 3350 (MIRALAX) as he had trouble going to the bathroom because he didn't had control and had trouble with bowel movement, he started when he left the hospital, so he can get back to his bowel, but he stopped using it couple of days ago as he started to go to the bathroom on his own again. The patient received both doses of Pfizer covid vaccine. He had a serious reaction to the vaccine, he couldn't go to the bathroom on his own, he had no control from his waist down, he needed a catheter as he was not able to pee or poop. He was admitted to the emergency room on 16Jun2021 and spent 3 days in the ICU because he could not walk and move, spent 3 days in out the down rated version, total 6 days in the hospital. He was diagnosed with Guillain-Barre syndrome and he was in the hospital on his birthday in Jun2021 and was doing physical therapy to walk and run again. His mother was trying to deal with the covid compensation because they had work. She and her husband were alone in the hospital. She reported that their medical bills were going to be crazy because they had to go by ambulance from one hospital to other because they were afraid of Guillain-Barre syndrome. The patient didn't have any movement in his legs all the way up to his heart. He was not able to play any sport because he can't run. The patient was discharged from the hospital and was on physical therapy (water therapy). The patient underwent lab tests and procedures which included two MRI, spinal test, and blood work with unknown results in the emergency room as they weren't sure what was going on with him. The patient was treated with IVIG and blood thinner everyday two times a day. The outcome of all the events were unknown. Information on Lot/Batch number was available. Additional information has been requested. Follow-up attempts are completed. No further information is expected.

6/7 - patient received 2nd dose of Pfizer vaccine. 6/8 - patient developed tactile fevers (for 2-3 days), diarrhea (4-5 days of non-bloody diarrhea) 6/9 - developed chest pain and tightness and mild cough 6/12 - few episodes of NBNB emesis, cough with blood tinged sputum 6/13 - presented to urgent care, referred to hospital and admitted to floor. Patient found to have tachycardia and hypertension. CXR with pleural effusion, renal US with medical renal disease. Worsening renal function and concern for hyper coagulable state with worsening D-Dimer and possible pulmonary embolus but unable to obtain contrast images due to renal failure. 6/15 - transferred to ICU for heparin drip for worsening D-dimer. Nephrology, rheumatology and infectious disease consulted. Continued chest pain, cough with hemoptysis. Remains afebrile and otherwise hemodynamically stable. Started on ceftriaxone empirically. Concern for MIS-C, vaccine related adverse event vs autoimmune vasculitis.

15 yo male with myocarditis following 2nd dose of pfizer COVID-19 vaccine. He reports that he received the Pfizer COVID-19 vaccine on 6/16/21. In the 1-2 days following the vaccine he experienced fatigue, body aches, and fever to Tmax 101F. Family treated this with anti-pyretics. On 6/18 he started having a pain in his left chest. He was again febrile at that time. On the day of admission his chest pain was worse and he was experiencing pain all over his body. He was noted to be tachycardic in the ED. His initial labs showed a modestly elevated BNP to 593 with a markedly elevated troponin to 1233. CRP was mildly elevated at 3.8. Electrolytes were unremarkable as were LFTs. CBC w/ diff showed an absolute lymphopenia with ALC of 1000 but was otherwise unremarkable. D-Dimer was normal. He was admitted initially to hospital medicine and then was transferred to the ICU due to concern for risk of developing a cardiac arrhythmia. An echocardiogram done showed trace mitral regurgitation but was otherwise normal with normal LV function. CXR was fairly unremarkable. Coags are normal. Repeat electrolytes showed a slight bump in his creatinine. LFTs largely unchaged and procalcitonin of 0.16. He does have a past medical history of PCR proven COVID-19 disease in December 2020.

Admitted on 6/18 with fever, pain at injection site and chest pain. Evaluated at local ED, found to have an elevated troponin to 12 and ST elevation in anterolat leads by report on EKG. An ECHO was obtained and revealed decreased EF to 47% and he was transferred to our hospital, initially monitored with telemetry, troponin levels every 6 hours and started on scheduled ibuprofen. Troponin peaked at 22.82 first hospital night on 6/18, then down-trending. Telemetry was without any ectopy. Symptoms improved and hemodynamically stable throughout his PICU course. Transferred to the pediatric floor on 6/19, continued to do well. Discharged on 6/20 with troponin of 5.92 ng/mL and EF of 55-60% on ECHO.

Received 1st dose of Pfizer Covid Vaccine and started becoming increasingly manic within about an hour. Complained of stomach discomfort. Became increasingly anxious and manic and was only able to sleep for two hours (received at 4pm, slept from 12am to 2am). Awake and manic the day following. Complained of stomach pain. Eating normally with no other symptoms. Started complaining of being cold and chills. Applied rotating heated blankets until he feel asleep about 10pm. Woke up at 2am. Manic and anxious. Stomach started swelling more and becoming rigid. Gave him Miralax. No change in swelling. Increased stomach pain. Gave him a suppository. Immediate small bowel movement. After two more hours and no change in swelling, gave a second suppository. Immediate small bowel movement. Stomach becoming distended and complaining of increased pain. Took him to the ER. Pain amplified on the way. Admitted to PICU after EKG in ER. Quickly declined and went into respiratory failure. Right lung had no air exchange and left lung collapsed. Myocarditis, pleural effusion, kidney damage and new onset Type I diabetes. Unexplained pneumonia. No growth from fluid in lung.